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Dr Nick Hudson
Dr

Nick Hudson

Email: 
Phone: 
+61 7 54601 521

Overview

Background

Nick is interested in fostering efficient, environmentally friendly animal production enterprises. He uses the data and capabilities provided by modern 'omics technologies to help improve breeding decisions and to inform other types of 'on farm' intervention.

Nick has a parallel interest in the development, physiology, metabolism and conservation of native Australian species, particularly frogs and butterflies.

Nick is a metabolic biochemist by training with research expertise in a) the handling and biological interpretation of large, complex data sets b) molecular technologies c) mitochondrial physiology and d) metabolic flux.

Nick enjoys teaching various aspects of biochemistry and molecular biology to both undergraduate and postgraduate students. He highlights the main themes using the comparative method and illustrates their importance through applied examples from agriculture and other areas of human endeavour.

Before taking his current position as a Teaching and Research academic in the School of Agriculture and Food Sustainability (AGFS) Nick worked for the CSIRO in a research intensive multi-disciplinary Systems Biology group.

Through this group he helped develop and apply bioinformatic methods that used metabolite, protein, RNA and DNA biotech to understand, model and predict phenotypes of commercial importance in cattle, sheep, pigs and chickens.

A research highlight from this time was the co-invention of a universal method for inferring causal molecules from genome-wide gene expression data (Hudson et al 2009. PLoS Comp Biol e1000382). This method has been applied across a diverse range of model systems including human kidney cancer and commercial traits in various agricultural species.

Following an undergraduate degree in Animal Biology at the University of St.Andrews, Nick was awarded his PhD through what was then the Zoology department of the University of Queensland, after travelling from England on a Britain-Australia Society funded Northcote Scholarship.

Availability

Dr Nick Hudson is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, The University of Queensland

Research interests

  • Productive, efficient farm animals

  • Wildlife biology of butterflies and frogs

  • Mitochondrial physiology

  • Metabolism

  • Flux analysis

  • Agricultural resource utilisation

Research impacts

Nick is an active science communicator whose research has been disseminated through print, radio and television media.

He hopes to make an impact on agricultural resource utilisation through a better understanding of production animal feed efficiency, and to sustainable agriculture through an understanding of agro-ecology and wildlife biology.

Nick has a very active national and international network of collaborators from academe, government agencies and industry.

This collaborative network has provided stimulating insights into industrial problems and how novel technologies and innovative concepts may inspire creative solutions.

Works

Search Professor Nick Hudson’s works on UQ eSpace

91 works between 2000 and 2024

21 - 40 of 91 works

2021

Conference Publication

Feed intake is regulated by metabolic mechanisms in young wethers fed diets deficient in crude protein and phosphorus

Innes, D. J., Hudson N. J., Anderson, S. T., Poppi, D. P. and Quigley, S. P. (2021). Feed intake is regulated by metabolic mechanisms in young wethers fed diets deficient in crude protein and phosphorus. 33rd Biennial Conference of the Australian Association of Animal Sciences, Fremantle, WA Australia, 1-3 Febraury 2021. Orange, NSW Australia: Australian Association of Animal Sciences.

Feed intake is regulated by metabolic mechanisms in young wethers fed diets deficient in crude protein and phosphorus

2021

Journal Article

Upstream Regulator Analysis of Wooden Breast Myopathy Proteomics in Commercial Broilers and Comparison to Feed Efficiency Proteomics in Pedigree Male Broilers

Bottje, Walter G., Lassiter, Kentu R., Kuttappan, Vivek A., Hudson, Nicholas J., Owens, Casey M., Abasht, Behnam, Dridi, Sami and Kong, Byungwhi C. (2021). Upstream Regulator Analysis of Wooden Breast Myopathy Proteomics in Commercial Broilers and Comparison to Feed Efficiency Proteomics in Pedigree Male Broilers. Foods (Basel, Switzerland), 10 (1) 104, 104. doi: 10.3390/foods10010104

Upstream Regulator Analysis of Wooden Breast Myopathy Proteomics in Commercial Broilers and Comparison to Feed Efficiency Proteomics in Pedigree Male Broilers

2021

Journal Article

Space use, interaction and recursion in a solitary specialized herbivore: a red panda case study

Bista, Damber, Baxter, Greg S., Hudson, Nicholas J., Lama, Sonam Tashi, Weerman, Janno and Murray, Peter J. (2021). Space use, interaction and recursion in a solitary specialized herbivore: a red panda case study. Endangered Species Research, 47, 131-143. doi: 10.3354/esr01171

Space use, interaction and recursion in a solitary specialized herbivore: a red panda case study

2020

Journal Article

A low-density SNP genotyping panel for the accurate prediction of cattle breeds

Reverter, Antonio, Hudson, Nicholas J., McWilliam, Sean, Alexandre, Pamela A., Li, Yutao, Barlow, Robert, Welti, Nina, Daetwyler, Hans, Porto-Neto, Laercio R. and Dominik, Sonja (2020). A low-density SNP genotyping panel for the accurate prediction of cattle breeds. Journal of Animal Science, 98 (11) skaa337, 1-10. doi: 10.1093/jas/skaa337

A low-density SNP genotyping panel for the accurate prediction of cattle breeds

2020

Journal Article

Genome-wide co-expression distributions as a metric to prioritize genes of functional importance

Alexandre, Pâmela A., Hudson, Nicholas J., Lehnert, Sigrid A., Fortes, Marina R. S., Naval-Sánchez, Marina, Nguyen, Loan T., Porto-Neto, Laercio R. and Reverter, Antonio (2020). Genome-wide co-expression distributions as a metric to prioritize genes of functional importance. Genes, 11 (10) 1231, 1231-13. doi: 10.3390/genes11101231

Genome-wide co-expression distributions as a metric to prioritize genes of functional importance

2020

Journal Article

Dynamics of gene co-expression networks in time-series data: a case study in Drosophila melanogaster embryogenesis

Lau, Li Yieng, Reverter, Antonio, Hudson, Nicholas J., Naval-Sanchez, Marina, Fortes, Marina R. S. and Alexandre, Pâmela A. (2020). Dynamics of gene co-expression networks in time-series data: a case study in Drosophila melanogaster embryogenesis. Frontiers in Genetics, 11 517, 517. doi: 10.3389/fgene.2020.00517

Dynamics of gene co-expression networks in time-series data: a case study in Drosophila melanogaster embryogenesis

2020

Journal Article

The efficacy of sunitinib treatment of renal cancer cells is associated with the protein PHAX in vitro

Al-Lamki, Rafia S., Hudson, Nicholas J., Bradley, John R., Warren, Anne Y., Eisen, Tim, Welsh, Sarah J., Riddick, Antony C. P., O’Mahony, Fiach C., Turnbull, Arran, Powles, Thomas, SCOTRRCC Collaborative, Reverter, Antonio, Harrison, David J. and Stewart, Grant D. (2020). The efficacy of sunitinib treatment of renal cancer cells is associated with the protein PHAX in vitro. Biology, 9 (4) 74, 1-21. doi: 10.3390/biology9040074

The efficacy of sunitinib treatment of renal cancer cells is associated with the protein PHAX in vitro

2020

Journal Article

Association analysis of loci implied in 'buffering' epistasis

Reverter, Antonio, Vitezica, Zulma G., Naval-Sánchez, Marina, Henshall, John, Raidan, Fernanda, Li, Yutao, Meyer, Karin, Hudson, Nicholas J., Porto-Neto, Laercio R. and Legarra, Andrés (2020). Association analysis of loci implied in 'buffering' epistasis. Journal of Animal Science, 98 (3) skaa045. doi: 10.1093/jas/skaa045

Association analysis of loci implied in 'buffering' epistasis

2020

Journal Article

Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle

Hudson, Nicholas J., Reverter, Antonio, Griffiths, William J., Yutuc, Eylan, Wang, Yuqin, Jeanes, Angela, McWilliam, Sean, Pethick, David W. and Greenwood, Paul L. (2020). Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle. BMC Genomics, 21 (1) 77, 77. doi: 10.1186/s12864-020-6505-4

Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle

2019

Journal Article

Visual opsin diversity in sharks and rays

Hart, Nathan S., Lamb, Trevor D., Patel, Hardip R., Chuah, Aaron, Natoli, Riccardo C., Hudson, Nicholas J., Cutmore, Scott C., Davies, Wayne I. L., Collin, Shaun P. and Hunt, David M. (2019). Visual opsin diversity in sharks and rays. Molecular Biology and Evolution, 37 (3), 811-827. doi: 10.1093/molbev/msz269

Visual opsin diversity in sharks and rays

2019

Conference Publication

Differential gene expression in three regions of the hypothalamus of steers with different protein and energy intake

Innes, David, Poppi, Dennis, Anderson, Stephen, Hudson, Nicholas, Kidd, Lisa, Antari, Risa and Quigley, Simon (2019). Differential gene expression in three regions of the hypothalamus of steers with different protein and energy intake. International Symposium on Ruminant Physiology, Leipzig, Germany, 6-9 September 2019. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/S2040470019000037

Differential gene expression in three regions of the hypothalamus of steers with different protein and energy intake

2019

Conference Publication

Development of a molecular assay to estimate mitochondrial content in cattle tissues

Mahmoudi, M., Jeanes, A., Kidd, L., Poppi, D., Quigley, S. and Hudson, N. J. (2019). Development of a molecular assay to estimate mitochondrial content in cattle tissues. 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition, Belo Horizonte, Minas Gerais, Brazil, 9-12 September 2019. The Netherlands: Wageningen Academic Publishers. doi: 10.3920/978-90-8686-891-9_122

Development of a molecular assay to estimate mitochondrial content in cattle tissues

2018

Journal Article

MicroRNA profiling associated with muscle growth in modern broilers compared to an unselected chicken breed

Khatri, Bhuwan, Seo, Dongwon, Shouse, Stephanie, Pan, Jeong Hoon, Hudson, Nicholas J., Kim, Jae Kyeom, Bottje, Walter and Kong, Byungwhi C. (2018). MicroRNA profiling associated with muscle growth in modern broilers compared to an unselected chicken breed. BMC Genomics, 19 (1) 683, 683. doi: 10.1186/s12864-018-5061-7

MicroRNA profiling associated with muscle growth in modern broilers compared to an unselected chicken breed

2018

Journal Article

A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs

Hudson, Nicholas J., Naval-Sánchez, Marina, Porto-Neto, Laercio, Pérez-Enciso, Miguel and Reverter, Antonio (2018). A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs. Journal of Animal Science, 96 (8), 3064-3069. doi: 10.1093/jas/sky225

A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs

2017

Journal Article

Molecular regulation of muscle mass in developing Blonde d’Aquitaine foetuses compared to Charolais

Cassar-Malek, Isabelle , Boby, Céline , Picard, Brigitte, Reverter, Antonio and Hudson, Nicholas J. (2017). Molecular regulation of muscle mass in developing Blonde d’Aquitaine foetuses compared to Charolais. Biology Open, 6 (10), 1483-1492. doi: 10.1242/bio.024950

Molecular regulation of muscle mass in developing Blonde d’Aquitaine foetuses compared to Charolais

2017

Journal Article

A pathway-centered analysis of pig domestication and breeding in eurasia

Leno-Colorado, Jordi, Hudson, Nick J., Reverter, Antonio and Pérez-Enciso, Miguel (2017). A pathway-centered analysis of pig domestication and breeding in eurasia. G3: Genes, Genomes, Genetics, 7 (7), 2171-2184. doi: 10.1534/g3.117.042671

A pathway-centered analysis of pig domestication and breeding in eurasia

2017

Journal Article

Data compression can discriminate broilers by selection line, detect haplotypes, and estimate genetic potential for complex phenotypes

Hudson, N. J., Hawken, R. J., Okimoto, R., Sapp, R. L. and Reverter, A. (2017). Data compression can discriminate broilers by selection line, detect haplotypes, and estimate genetic potential for complex phenotypes. Poultry Science, 96 (9), 3031-3038. doi: 10.3382/ps/pex151

Data compression can discriminate broilers by selection line, detect haplotypes, and estimate genetic potential for complex phenotypes

2017

Journal Article

Proteogenomics reveals enriched ribosome assembly and protein translation in Pectoralis major of high feed efficiency pedigree broiler males

Bottje, Walter G., Lassiter, Kentu, Piekarski-Welsher, Alissa, Dridi, Sami, Reverter, Antonio, Hudson, Nicholas J. and Kong, Byung-Whi (2017). Proteogenomics reveals enriched ribosome assembly and protein translation in Pectoralis major of high feed efficiency pedigree broiler males. Frontiers in Physiology, 8 (MAY) 306. doi: 10.3389/fphys.2017.00306

Proteogenomics reveals enriched ribosome assembly and protein translation in Pectoralis major of high feed efficiency pedigree broiler males

2017

Journal Article

Progesterone signalling in broiler skeletal muscle is associated with divergent feed efficiency

Bottje, Walter, Kong, Byung-Whi, Reverter, Antonio, Waardenberg, Ashley J., Lassiter, Kentu and Hudson, Nicholas J. (2017). Progesterone signalling in broiler skeletal muscle is associated with divergent feed efficiency. BMC Systems Biology, 11 (1) 29. doi: 10.1186/s12918-017-0396-2

Progesterone signalling in broiler skeletal muscle is associated with divergent feed efficiency

2017

Journal Article

The 'heritability' of domestication and its functional partitioning in the pig

Perez-Enciso, M., De Los Campos, G., Hudson, N., Kijas, J. and Reverter, A. (2017). The 'heritability' of domestication and its functional partitioning in the pig. Heredity, 118 (2), 160-168. doi: 10.1038/hdy.2016.78

The 'heritability' of domestication and its functional partitioning in the pig

Funding

Current funding

  • 2023 - 2024
    Innate immune response to Ross River virus infection in horses
    Research Donation Generic
    Open grant
  • 2022 - 2026
    LESTR Low Emission Saliva Test for Ruminants
    Meat & Livestock Australia
    Open grant

Past funding

  • 2019 - 2020
    Understanding the Mechanisms of West Nile virus (WNV) induced lesions in the Australian saltwater crocodile (Crocodylus porosus)
    Research Donation Generic
    Open grant
  • 2019 - 2022
    How do brains become lateralised? (ARC Discovery Project administered by Macquarie University)
    Macquarie University
    Open grant
  • 2019 - 2022
    Increased pasture intake and reduced supplement requirements of sheep/cattle
    Meat & Livestock Australia
    Open grant
  • 2018 - 2020
    The gateway to selecting for nutrient efficient livestock - ''Better doers'' (Meat and Livestock Australia grant administered by NSW Department of Primary Industries)
    New South Wales Department of Primary Industries
    Open grant
  • 2017
    Towards a high-throughput metabolic phenotyping capability for production animals and plants
    UQ Major Equipment and Infrastructure
    Open grant

Supervision

Availability

Dr Nick Hudson is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Mitochondria and livestock feed efficiency

    Some production animals utilise feed more efficiently for production than others, while some are able to maintain muscle mass, liveweight and productivity under periods of nutritional and environmental stress.

    Why is this? The successful applicant will focus their research on the biology of the mitochondria and its role in determining metabolic efficiency in cattle.

  • Frog and butterfly ecology

    Projects regarding the fundamental biology and ecology of both frogs and butterflies are available.

    Fieldwork will be based at Hiddenvale Research Station (https://hiddenvalewildlife.uq.edu.au/). There is a lot of scope for flexibility in project development so if you have any ideas - or even just a passion for - these two groups of animals please get in touch.

  • Metabolism across species

    Are you interested in growth, development and metabolism? Students are encouraged to get in touch with any of their own ideas in the broad area of animal biology. Projects can be developed collaboratively with other academics within and beyond AGFS so there is lots of scope for diversity and inter-disciplinary research.

    We encourage students to develope their own ideas and projects. In our lab we use a range of metabolic and molecular tools such as gene expression, metabolic flux analysis and SNP genotyping that can be readily applied across species and biological circumstances.

    You can learn how to handle and quantitate DNA and RNA, run an agarose gel, estimate gene expression by quantitative PCR and phenotype animal and plant cells in the state of the art XFe24 Flux analyser.

    Remember, a new discovery is just round the corner!

  • The interface between genomes and diet in ruminant farm animals

    Livestock products provide a nutritious source of protein (and a range of other molecules including bioavailable iron and vitamin B12). More efficient production may be required to meet not only increasing demand but also greater awareness over welfare issues and environmental footprint.

    Breeds and individual cattle and sheep can show substantial differences in how they respond to diets, with some animals more productive than others. The proposed research will investigate which parts of the genome underpin productivity in cattle and sheep.

    Biochemical pathways relevant to the new science of nutrigenomics will be uncovered primarily through investigation of genome-wide gene expression data sets available for metabolically important tissues such as muscle, fat and liver.

    Cutting edge bioinformatics tools including the latest approaches from network science will be deployed. This knowledge may help us understand why some animals fare better than others under given nutritional circumstances and perhaps inform decisions regarding diet formulation.

Supervision history

Current supervision

  • Doctor Philosophy

    Cellular oxidative damage and ruminant feed efficiency

    Principal Advisor

    Other advisors: Associate Professor Marina Fortes

  • Doctor Philosophy

    Using Systems Biology to understand the genetic basis of bull fertility phenotypes and their covariance

    Associate Advisor

    Other advisors: Associate Professor Marina Fortes

Completed supervision

Media

Enquiries

Contact Dr Nick Hudson directly for media enquiries about:

  • feed efficiency
  • flux analysis
  • functional genomics
  • mitochondria
  • muscle growth
  • production animals

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au