
Overview
Background
Nick is interested in fostering efficient, environmentally friendly animal production enterprises. He uses the data and capabilities provided by modern 'omics technologies to help improve breeding decisions and to inform other types of 'on farm' intervention.
Nick has a parallel interest in the development, physiology, metabolism and conservation of native Australian species, particularly frogs and butterflies.
Nick is a metabolic biochemist by training with research expertise in a) the handling and biological interpretation of large, complex data sets b) molecular technologies c) mitochondrial physiology and d) metabolic flux.
Nick enjoys teaching various aspects of biochemistry and molecular biology to both undergraduate and postgraduate students. He highlights the main themes using the comparative method and illustrates their importance through applied examples from agriculture and other areas of human endeavour.
Before taking his current position as a Teaching and Research academic in the School of Agriculture and Food Sustainability (AGFS) Nick worked for the CSIRO in a research intensive multi-disciplinary Systems Biology group.
Through this group he helped develop and apply bioinformatic methods that used metabolite, protein, RNA and DNA biotech to understand, model and predict phenotypes of commercial importance in cattle, sheep, pigs and chickens.
A research highlight from this time was the co-invention of a universal method for inferring causal molecules from genome-wide gene expression data (Hudson et al 2009. PLoS Comp Biol e1000382). This method has been applied across a diverse range of model systems including human kidney cancer and commercial traits in various agricultural species.
Following an undergraduate degree in Animal Biology at the University of St.Andrews, Nick was awarded his PhD through what was then the Zoology department of the University of Queensland, after travelling from England on a Britain-Australia Society funded Northcote Scholarship.
Availability
- Dr Nick Hudson is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, The University of Queensland
Research interests
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Productive, efficient farm animals
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Wildlife biology of butterflies and frogs
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Mitochondrial physiology
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Metabolism
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Flux analysis
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Agricultural resource utilisation
Research impacts
Nick is an active science communicator whose research has been disseminated through print, radio and television media.
He hopes to make an impact on agricultural resource utilisation through a better understanding of production animal feed efficiency, and to sustainable agriculture through an understanding of agro-ecology and wildlife biology.
Nick has a very active national and international network of collaborators from academe, government agencies and industry.
This collaborative network has provided stimulating insights into industrial problems and how novel technologies and innovative concepts may inspire creative solutions.
Works
Search Professor Nick Hudson’s works on UQ eSpace
2021
Journal Article
Movement and dispersal of a habitat specialist in human-dominated landscapes: a case study of the red panda
Bista, Damber, Baxter, Greg S., Hudson, Nicholas J., Lama, Sonam Tashi, Weerman, Janno and Murray, Peter John (2021). Movement and dispersal of a habitat specialist in human-dominated landscapes: a case study of the red panda. Movement Ecology, 9 (1) 62, 62. doi: 10.1186/s40462-021-00297-z
2021
Journal Article
Effect of disturbances and habitat fragmentation on an arboreal habitat specialist mammal using GPS telemetry: a case of the red panda
Bista, Damber, Baxter, Greg S., Hudson, Nicholas J., Lama, Sonam Tashi and Murray, Peter John (2021). Effect of disturbances and habitat fragmentation on an arboreal habitat specialist mammal using GPS telemetry: a case of the red panda. Landscape Ecology, 37 (3), 1-15. doi: 10.1007/s10980-021-01357-w
2021
Journal Article
First record of Bengal Tiger, Panthera tigris tigris Linnaeus, 1758 (Felidae), in eastern Nepal
Bista, Damber, Lama, Sonam Tashi, Shrestha, Janam, Rumba, Yam Bahadur, Weerman, Janno, Thapa, Madhuri, Acharya, Haribhadra, Sherpa, Ang Phuri, Hudson, Nicholas J., Baxter, Greg S. and Murray, Peter John (2021). First record of Bengal Tiger, Panthera tigris tigris Linnaeus, 1758 (Felidae), in eastern Nepal. Check List, 17 (5), 1249-1253. doi: 10.15560/17.5.1249
2021
Journal Article
A conserved haplotype in Wagyu cattle contains RAB4A whose encoded protein regulates glucose trafficking in muscle and fat cells
Hudson, N. J., Porto-Neto, L., Naval-Sanchez, M., Lyons, R. E. and Reverter, Antonio (2021). A conserved haplotype in Wagyu cattle contains RAB4A whose encoded protein regulates glucose trafficking in muscle and fat cells. Animal Genetics, 52 (3), 275-283. doi: 10.1111/age.13054
2021
Journal Article
Improved trapping and handling of an arboreal, montane mammal: Red panda Ailurus fulgens
Bista, Damber, Lama, Sonam Tashi, Weerman, Janno, Sherpa, Ang Phuri, Pandey, Purushotam, Thapa, Madhuri Karki, Acharya, Haribhadra, Hudson, Nicholas J., Baxter, Greg S. and Murray, Peter John (2021). Improved trapping and handling of an arboreal, montane mammal: Red panda Ailurus fulgens. Animals, 11 (4) 921, 1-13. doi: 10.3390/ani11040921
2021
Conference Publication
Feed intake is regulated by metabolic mechanisms in young wethers fed diets deficient in crude protein and phosphorus
Innes, D. J., Hudson N. J., Anderson, S. T., Poppi, D. P. and Quigley, S. P. (2021). Feed intake is regulated by metabolic mechanisms in young wethers fed diets deficient in crude protein and phosphorus. 33rd Biennial Conference of the Australian Association of Animal Sciences, Fremantle, WA Australia, 1-3 Febraury 2021. Orange, NSW Australia: Australian Association of Animal Sciences.
2021
Journal Article
Upstream Regulator Analysis of Wooden Breast Myopathy Proteomics in Commercial Broilers and Comparison to Feed Efficiency Proteomics in Pedigree Male Broilers
Bottje, Walter G., Lassiter, Kentu R., Kuttappan, Vivek A., Hudson, Nicholas J., Owens, Casey M., Abasht, Behnam, Dridi, Sami and Kong, Byungwhi C. (2021). Upstream Regulator Analysis of Wooden Breast Myopathy Proteomics in Commercial Broilers and Comparison to Feed Efficiency Proteomics in Pedigree Male Broilers. Foods (Basel, Switzerland), 10 (1) 104, 104. doi: 10.3390/foods10010104
2021
Journal Article
Space use, interaction and recursion in a solitary specialized herbivore: a red panda case study
Bista, Damber, Baxter, Greg S., Hudson, Nicholas J., Lama, Sonam Tashi, Weerman, Janno and Murray, Peter J. (2021). Space use, interaction and recursion in a solitary specialized herbivore: a red panda case study. Endangered Species Research, 47, 131-143. doi: 10.3354/esr01171
2020
Journal Article
A low-density SNP genotyping panel for the accurate prediction of cattle breeds
Reverter, Antonio, Hudson, Nicholas J., McWilliam, Sean, Alexandre, Pamela A., Li, Yutao, Barlow, Robert, Welti, Nina, Daetwyler, Hans, Porto-Neto, Laercio R. and Dominik, Sonja (2020). A low-density SNP genotyping panel for the accurate prediction of cattle breeds. Journal of Animal Science, 98 (11) skaa337, 1-10. doi: 10.1093/jas/skaa337
2020
Journal Article
Genome-wide co-expression distributions as a metric to prioritize genes of functional importance
Alexandre, Pâmela A., Hudson, Nicholas J., Lehnert, Sigrid A., Fortes, Marina R. S., Naval-Sánchez, Marina, Nguyen, Loan T., Porto-Neto, Laercio R. and Reverter, Antonio (2020). Genome-wide co-expression distributions as a metric to prioritize genes of functional importance. Genes, 11 (10) 1231, 1231-13. doi: 10.3390/genes11101231
2020
Journal Article
Dynamics of gene co-expression networks in time-series data: a case study in Drosophila melanogaster embryogenesis
Lau, Li Yieng, Reverter, Antonio, Hudson, Nicholas J., Naval-Sanchez, Marina, Fortes, Marina R. S. and Alexandre, Pâmela A. (2020). Dynamics of gene co-expression networks in time-series data: a case study in Drosophila melanogaster embryogenesis. Frontiers in Genetics, 11 517, 517. doi: 10.3389/fgene.2020.00517
2020
Journal Article
The efficacy of sunitinib treatment of renal cancer cells is associated with the protein PHAX in vitro
Al-Lamki, Rafia S., Hudson, Nicholas J., Bradley, John R., Warren, Anne Y., Eisen, Tim, Welsh, Sarah J., Riddick, Antony C. P., O’Mahony, Fiach C., Turnbull, Arran, Powles, Thomas, SCOTRRCC Collaborative, Reverter, Antonio, Harrison, David J. and Stewart, Grant D. (2020). The efficacy of sunitinib treatment of renal cancer cells is associated with the protein PHAX in vitro. Biology, 9 (4) 74, 1-21. doi: 10.3390/biology9040074
2020
Journal Article
Association analysis of loci implied in 'buffering' epistasis
Reverter, Antonio, Vitezica, Zulma G., Naval-Sánchez, Marina, Henshall, John, Raidan, Fernanda, Li, Yutao, Meyer, Karin, Hudson, Nicholas J., Porto-Neto, Laercio R. and Legarra, Andrés (2020). Association analysis of loci implied in 'buffering' epistasis. Journal of Animal Science, 98 (3) skaa045. doi: 10.1093/jas/skaa045
2020
Journal Article
Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle
Hudson, Nicholas J., Reverter, Antonio, Griffiths, William J., Yutuc, Eylan, Wang, Yuqin, Jeanes, Angela, McWilliam, Sean, Pethick, David W. and Greenwood, Paul L. (2020). Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle. BMC Genomics, 21 (1) 77, 77. doi: 10.1186/s12864-020-6505-4
2019
Journal Article
Visual opsin diversity in sharks and rays
Hart, Nathan S., Lamb, Trevor D., Patel, Hardip R., Chuah, Aaron, Natoli, Riccardo C., Hudson, Nicholas J., Cutmore, Scott C., Davies, Wayne I. L., Collin, Shaun P. and Hunt, David M. (2019). Visual opsin diversity in sharks and rays. Molecular Biology and Evolution, 37 (3), 811-827. doi: 10.1093/molbev/msz269
2019
Conference Publication
Development of a molecular assay to estimate mitochondrial content in cattle tissues
Mahmoudi, M., Jeanes, A., Kidd, L., Poppi, D., Quigley, S. and Hudson, N. J. (2019). Development of a molecular assay to estimate mitochondrial content in cattle tissues. 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition, Belo Horizonte, Minas Gerais, Brazil, 9-12 September 2019. The Netherlands: Wageningen Academic Publishers. doi: 10.3920/978-90-8686-891-9_122
2019
Conference Publication
Differential gene expression in three regions of the hypothalamus of steers with different protein and energy intake
Innes, David, Poppi, Dennis, Anderson, Stephen, Hudson, Nicholas, Kidd, Lisa, Antari, Risa and Quigley, Simon (2019). Differential gene expression in three regions of the hypothalamus of steers with different protein and energy intake. International Symposium on Ruminant Physiology, Leipzig, Germany, 6-9 September 2019. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/S2040470019000037
2018
Journal Article
MicroRNA profiling associated with muscle growth in modern broilers compared to an unselected chicken breed
Khatri, Bhuwan, Seo, Dongwon, Shouse, Stephanie, Pan, Jeong Hoon, Hudson, Nicholas J., Kim, Jae Kyeom, Bottje, Walter and Kong, Byungwhi C. (2018). MicroRNA profiling associated with muscle growth in modern broilers compared to an unselected chicken breed. BMC Genomics, 19 (1) 683, 683. doi: 10.1186/s12864-018-5061-7
2018
Journal Article
A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs
Hudson, Nicholas J., Naval-Sánchez, Marina, Porto-Neto, Laercio, Pérez-Enciso, Miguel and Reverter, Antonio (2018). A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs. Journal of Animal Science, 96 (8), 3064-3069. doi: 10.1093/jas/sky225
2017
Journal Article
Molecular regulation of muscle mass in developing Blonde d’Aquitaine foetuses compared to Charolais
Cassar-Malek, Isabelle , Boby, Céline , Picard, Brigitte, Reverter, Antonio and Hudson, Nicholas J. (2017). Molecular regulation of muscle mass in developing Blonde d’Aquitaine foetuses compared to Charolais. Biology Open, 6 (10), 1483-1492. doi: 10.1242/bio.024950
Funding
Current funding
Past funding
Supervision
Availability
- Dr Nick Hudson is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Mitochondria and livestock feed efficiency
Some production animals utilise feed more efficiently for production than others, while some are able to maintain muscle mass, liveweight and productivity under periods of nutritional and environmental stress.
Why is this? The successful applicant will focus their research on the biology of the mitochondria and its role in determining metabolic efficiency in cattle.
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Frog and butterfly ecology
Projects regarding the fundamental biology and ecology of both frogs and butterflies are available.
Fieldwork will be based at Hiddenvale Research Station (https://hiddenvalewildlife.uq.edu.au/). There is a lot of scope for flexibility in project development so if you have any ideas - or even just a passion for - these two groups of animals please get in touch.
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Metabolism across species
Are you interested in growth, development and metabolism? Students are encouraged to get in touch with any of their own ideas in the broad area of animal biology. Projects can be developed collaboratively with other academics within and beyond AGFS so there is lots of scope for diversity and inter-disciplinary research.
We encourage students to develope their own ideas and projects. In our lab we use a range of metabolic and molecular tools such as gene expression, metabolic flux analysis and SNP genotyping that can be readily applied across species and biological circumstances.
You can learn how to handle and quantitate DNA and RNA, run an agarose gel, estimate gene expression by quantitative PCR and phenotype animal and plant cells in the state of the art XFe24 Flux analyser.
Remember, a new discovery is just round the corner!
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The interface between genomes and diet in ruminant farm animals
Livestock products provide a nutritious source of protein (and a range of other molecules including bioavailable iron and vitamin B12). More efficient production may be required to meet not only increasing demand but also greater awareness over welfare issues and environmental footprint.
Breeds and individual cattle and sheep can show substantial differences in how they respond to diets, with some animals more productive than others. The proposed research will investigate which parts of the genome underpin productivity in cattle and sheep.
Biochemical pathways relevant to the new science of nutrigenomics will be uncovered primarily through investigation of genome-wide gene expression data sets available for metabolically important tissues such as muscle, fat and liver.
Cutting edge bioinformatics tools including the latest approaches from network science will be deployed. This knowledge may help us understand why some animals fare better than others under given nutritional circumstances and perhaps inform decisions regarding diet formulation.
Supervision history
Current supervision
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Doctor Philosophy
Cellular oxidative damage and ruminant feed efficiency
Principal Advisor
Other advisors: Associate Professor Marina Fortes
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Doctor Philosophy
Developing genomic resources to enable better breeding decisions for Rufous bettongs, Aepyprymnus rufescens.
Principal Advisor
Other advisors: Dr Loan Nguyen
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Doctor Philosophy
Investigating the genetics of industry-relevant indicator traits for bull fertility
Associate Advisor
Other advisors: Associate Professor Marina Fortes
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Doctor Philosophy
Genome wide association and machine learning approaches for the understanding of the genetic basis of bull fertility traits.
Associate Advisor
Other advisors: Associate Professor Marina Fortes
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Doctor Philosophy
Maternal-foetal programming of stress resilience in Merino sheep
Associate Advisor
Other advisors: Professor Alan Tilbrook
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Doctor Philosophy
Using Systems Biology to understand the genetic basis of bull fertility phenotypes and their covariance
Associate Advisor
Other advisors: Associate Professor Marina Fortes
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Doctor Philosophy
Extrinsic and intrinsic factors that influence the meat quality of goat fresh meat and products.
Associate Advisor
Other advisors: Dr Angela Lees, Dr Anne Beasley, Associate Professor Daniel Cozzolino, Professor Louw Hoffman
Completed supervision
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2022
Doctor Philosophy
Disturbance and fragmentation impacts movement ecology of a habitat specialist: conservation implications for red pandas
Principal Advisor
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2025
Doctor Philosophy
Investigating the genetics of industry-relevant indicator traits for bull fertility
Associate Advisor
Other advisors: Associate Professor Marina Fortes
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2024
Doctor Philosophy
Pathogenesis and Epidemiology of Zoonotic Mosquito-borne Diseases in Horses
Associate Advisor
Other advisors: Dr Lee McMichael, Professor Joerg Henning, Dr Albert Sole Guitart
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2022
Doctor Philosophy
Unpacking food systems: A systems approach to food packaging reduction
Associate Advisor
Other advisors: Dr Russell Richards, Professor Ammar Abdul Aziz
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2021
Doctor Philosophy
Intake regulation in ruminants consuming nutrient deficient diets
Associate Advisor
Other advisors: Associate Professor Stephen Anderson
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2012
Doctor Philosophy
GENE EXPRESSION STUDIES IN BOVINE SKELETAL MUSCLE: INVESTIGATIONS INTO THE EFFECTS OF HORMONE GROWTH PROMOTANT TREATMENT, ENVIRONMENT AND TENDERNESS GENOTYPE ASSOCIATED WITH TENDERNESS AND MARBLING
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard
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2010
Doctor Philosophy
Metabolic depression in Cyclorana alboguttata and the potential role of the endogenous opioid system and thyroid axis as regulators of aestivation
Associate Advisor
Other advisors: Professor Craig Franklin
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2008
Doctor Philosophy
Effect of Prolonged Aestivation on Muscle Morphology and Biochemistry in the Green-Striped Burrowing Frog, Cyclorana Alboguttata
Associate Advisor
Other advisors: Professor Craig Franklin
Media
Enquiries
Contact Dr Nick Hudson directly for media enquiries about:
- feed efficiency
- flux analysis
- functional genomics
- mitochondria
- muscle growth
- production animals
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: