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Dr Nick Hudson
Dr

Nick Hudson

Email: 
Phone: 
+61 7 54601 521

Overview

Background

Nick is interested in fostering efficient, environmentally friendly animal production enterprises. He uses the data and capabilities provided by modern 'omics technologies to help improve breeding decisions and to inform other types of 'on farm' intervention.

Nick has a parallel interest in the development, physiology, metabolism and conservation of native Australian species, particularly frogs and butterflies.

Nick is a metabolic biochemist by training with research expertise in a) the handling and biological interpretation of large, complex data sets b) molecular technologies c) mitochondrial physiology and d) metabolic flux.

Nick enjoys teaching various aspects of biochemistry and molecular biology to both undergraduate and postgraduate students. He highlights the main themes using the comparative method and illustrates their importance through applied examples from agriculture and other areas of human endeavour.

Before taking his current position as a Teaching and Research academic in the School of Agriculture and Food Sustainability (AGFS) Nick worked for the CSIRO in a research intensive multi-disciplinary Systems Biology group.

Through this group he helped develop and apply bioinformatic methods that used metabolite, protein, RNA and DNA biotech to understand, model and predict phenotypes of commercial importance in cattle, sheep, pigs and chickens.

A research highlight from this time was the co-invention of a universal method for inferring causal molecules from genome-wide gene expression data (Hudson et al 2009. PLoS Comp Biol e1000382). This method has been applied across a diverse range of model systems including human kidney cancer and commercial traits in various agricultural species.

Following an undergraduate degree in Animal Biology at the University of St.Andrews, Nick was awarded his PhD through what was then the Zoology department of the University of Queensland, after travelling from England on a Britain-Australia Society funded Northcote Scholarship.

Availability

Dr Nick Hudson is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, The University of Queensland

Research interests

  • Productive, efficient farm animals

  • Wildlife biology of butterflies and frogs

  • Mitochondrial physiology

  • Metabolism

  • Flux analysis

  • Agricultural resource utilisation

Research impacts

Nick is an active science communicator whose research has been disseminated through print, radio and television media.

He hopes to make an impact on agricultural resource utilisation through a better understanding of production animal feed efficiency, and to sustainable agriculture through an understanding of agro-ecology and wildlife biology.

Nick has a very active national and international network of collaborators from academe, government agencies and industry.

This collaborative network has provided stimulating insights into industrial problems and how novel technologies and innovative concepts may inspire creative solutions.

Works

Search Professor Nick Hudson’s works on UQ eSpace

96 works between 2000 and 2025

41 - 60 of 96 works

2017

Journal Article

A pathway-centered analysis of pig domestication and breeding in eurasia

Leno-Colorado, Jordi, Hudson, Nick J., Reverter, Antonio and Pérez-Enciso, Miguel (2017). A pathway-centered analysis of pig domestication and breeding in eurasia. G3: Genes, Genomes, Genetics, 7 (7), 2171-2184. doi: 10.1534/g3.117.042671

A pathway-centered analysis of pig domestication and breeding in eurasia

2017

Journal Article

Data compression can discriminate broilers by selection line, detect haplotypes, and estimate genetic potential for complex phenotypes

Hudson, N. J., Hawken, R. J., Okimoto, R., Sapp, R. L. and Reverter, A. (2017). Data compression can discriminate broilers by selection line, detect haplotypes, and estimate genetic potential for complex phenotypes. Poultry Science, 96 (9), 3031-3038. doi: 10.3382/ps/pex151

Data compression can discriminate broilers by selection line, detect haplotypes, and estimate genetic potential for complex phenotypes

2017

Journal Article

Proteogenomics reveals enriched ribosome assembly and protein translation in Pectoralis major of high feed efficiency pedigree broiler males

Bottje, Walter G., Lassiter, Kentu, Piekarski-Welsher, Alissa, Dridi, Sami, Reverter, Antonio, Hudson, Nicholas J. and Kong, Byung-Whi (2017). Proteogenomics reveals enriched ribosome assembly and protein translation in Pectoralis major of high feed efficiency pedigree broiler males. Frontiers in Physiology, 8 (MAY) 306. doi: 10.3389/fphys.2017.00306

Proteogenomics reveals enriched ribosome assembly and protein translation in Pectoralis major of high feed efficiency pedigree broiler males

2017

Journal Article

Progesterone signalling in broiler skeletal muscle is associated with divergent feed efficiency

Bottje, Walter, Kong, Byung-Whi, Reverter, Antonio, Waardenberg, Ashley J., Lassiter, Kentu and Hudson, Nicholas J. (2017). Progesterone signalling in broiler skeletal muscle is associated with divergent feed efficiency. BMC Systems Biology, 11 (1) 29. doi: 10.1186/s12918-017-0396-2

Progesterone signalling in broiler skeletal muscle is associated with divergent feed efficiency

2017

Journal Article

The 'heritability' of domestication and its functional partitioning in the pig

Perez-Enciso, M., De Los Campos, G., Hudson, N., Kijas, J. and Reverter, A. (2017). The 'heritability' of domestication and its functional partitioning in the pig. Heredity, 118 (2), 160-168. doi: 10.1038/hdy.2016.78

The 'heritability' of domestication and its functional partitioning in the pig

2017

Journal Article

Chicken muscle mitochondrial content appears co-ordinately regulated and is associated with performance phenotypes

Reverter, Antonio, Okimoto, Ron, Sapp, Robyn, Bottje, Walter G., Hawken, Rachel and Hudson, Nicholas J. (2017). Chicken muscle mitochondrial content appears co-ordinately regulated and is associated with performance phenotypes. Biology Open, 6 (1), 50-58. doi: 10.1242/bio.022772

Chicken muscle mitochondrial content appears co-ordinately regulated and is associated with performance phenotypes

2017

Journal Article

RNA sequencing for global gene expression associated with muscle growth in a single male modern broiler line compared to a foundational Barred Plymouth Rock chicken line

Kong, Byung-Whi, Hudson, Nicholas, Seo, Dongwon, Lee, Seok, Khatri, Bhuwan, Lassiter, Kentu, Cook, Devin, Piekarski, Alissa, Dridi, Sami, Anthony, Nicholas and Bottje, Walter (2017). RNA sequencing for global gene expression associated with muscle growth in a single male modern broiler line compared to a foundational Barred Plymouth Rock chicken line. BMC Genomics, 18 (1) 82. doi: 10.1186/s12864-016-3471-y

RNA sequencing for global gene expression associated with muscle growth in a single male modern broiler line compared to a foundational Barred Plymouth Rock chicken line

2017

Conference Publication

Mitochondrial metabolism: a driver of energy utilisation and product quality?

Hudson, N. J., Bottje, W. G., Hawken, R. J., Kong, ByungWhi, Okimoto, R. and Reverter, A. (2017). Mitochondrial metabolism: a driver of energy utilisation and product quality?. 2017 Recent Advances in Animal Nutrition, The University of New England, Armidale, NSW, Australia, 25-27 October 2017. Clayton, VIC Australia: CSIRO Publishing. doi: 10.1071/AN17322

Mitochondrial metabolism: a driver of energy utilisation and product quality?

2017

Journal Article

Enhanced expression of proteins involved in energy production and transfer in breast muscle of pedigree male broilers exhibiting high feed efficiency

Bottje, W. G. , Lassiter, K., Dridi, S., Hudson, N. and Kong, B. W. (2017). Enhanced expression of proteins involved in energy production and transfer in breast muscle of pedigree male broilers exhibiting high feed efficiency. Poultry Science, 96 (7), 2454-2458. doi: 10.3382/ps/pew453

Enhanced expression of proteins involved in energy production and transfer in breast muscle of pedigree male broilers exhibiting high feed efficiency

2016

Journal Article

Disorder of endoplasmic reticulum calcium channel components is associated with the increased apoptotic potential in pale, soft, exudative pork

Guo, Bing, Zhang, Wangang, Tume, Ron K., Hudson, Nicholas J., Huang, Feng, Yin, Yan and Zhou, Guanghong (2016). Disorder of endoplasmic reticulum calcium channel components is associated with the increased apoptotic potential in pale, soft, exudative pork. Meat Science, 115, 34-40. doi: 10.1016/j.meatsci.2016.01.003

Disorder of endoplasmic reticulum calcium channel components is associated with the increased apoptotic potential in pale, soft, exudative pork

2016

Journal Article

Proteomics of breast muscle tissue associated with the phenotypic expression of feed efficiency within a pedigree male broiler line: I. Highlight on mitochondria

Kong, Byung-Whi, Lassiter, Kentu, Piekarski-Welsher, Alissa, Dridi, Sami, Reverter-Gomez, Antonio, Hudson, Nicholas James and Bottje, Walter Gay (2016). Proteomics of breast muscle tissue associated with the phenotypic expression of feed efficiency within a pedigree male broiler line: I. Highlight on mitochondria. PloS One, 11 (5) e0159897, e0155679. doi: 10.1371/journal.pone.0155679

Proteomics of breast muscle tissue associated with the phenotypic expression of feed efficiency within a pedigree male broiler line: I. Highlight on mitochondria

2015

Journal Article

Compression distance can discriminate animals by genetic profile, build relationship matrices and estimate breeding values

Hudson, Nicholas J., Porto-Neto, Laercio, Kijas, James W. and Reverter, Antonio (2015). Compression distance can discriminate animals by genetic profile, build relationship matrices and estimate breeding values. Genetics Selection Evolution, 47 (1) 78. doi: 10.1186/s12711-015-0158-9

Compression distance can discriminate animals by genetic profile, build relationship matrices and estimate breeding values

2014

Journal Article

Longitudinal muscle gene expression patterns associated with differential intramuscular fat in cattle

Hudson, N. J., Reverter, A., Greenwood, P. L., Guo, B., Cafe, L. M. and Dalrymple, B. P. (2014). Longitudinal muscle gene expression patterns associated with differential intramuscular fat in cattle. Animal, 9 (4), 650-659. doi: 10.1017/S1751731114002754

Longitudinal muscle gene expression patterns associated with differential intramuscular fat in cattle

2014

Conference Publication

Upstream and Functional Analysis of Global Gene Expression Associated with Feed Efficiency in a Single Male Broiler Line

Kong, Byung-Whi, Dridi, Sami, Piekarski, Alissa, Lassiter, Kentu, Cook, Devin, Hudson, Nick and Bottje, Walt (2014). Upstream and Functional Analysis of Global Gene Expression Associated with Feed Efficiency in a Single Male Broiler Line. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.freeradbiomed.2014.10.255

Upstream and Functional Analysis of Global Gene Expression Associated with Feed Efficiency in a Single Male Broiler Line

2014

Journal Article

Sensory rewiring in an echolocator: genome-wide modification of retinogenic and auditory genes in the bat Myotis davidii

Hudson, Nicholas J., Baker, Michelle L., Hart, Nathan S., Wynne, James W., Gu, Quan, Huang, Zhiyong, Zhang, Guojie, Ingham, Aaron B., Wang, Linfa and Reverter, Antonio (2014). Sensory rewiring in an echolocator: genome-wide modification of retinogenic and auditory genes in the bat Myotis davidii. G3: Genes, Genomes, Genetics, 4 (10), 1825-1835. doi: 10.1534/g3.114.011262

Sensory rewiring in an echolocator: genome-wide modification of retinogenic and auditory genes in the bat Myotis davidii

2014

Journal Article

A marker-derived gene network reveals the regulatory role of PPARGC1A, HNF4G, and FOXP3 in intramuscular fat deposition of beef cattle

Ramayo-Caldas, Y., Fortes, M. R. S., Hudson, N. J., Porto-Neto, L. R., Bolormaa, S., Barendse, W., Kelly, M., Moore, S. S., Goddard, M. E., Lehnert, S. A. and Reverter, A. (2014). A marker-derived gene network reveals the regulatory role of PPARGC1A, HNF4G, and FOXP3 in intramuscular fat deposition of beef cattle. Journal of Animal Science, 92 (7), 2832-2845. doi: 10.2527/jas.2013-7484

A marker-derived gene network reveals the regulatory role of PPARGC1A, HNF4G, and FOXP3 in intramuscular fat deposition of beef cattle

2014

Journal Article

Differences in muscle transcriptome among pigs phenotypically extreme for fatty acid composition

Puig-Oliveras, Anna, Ramayo-Caldas, Yuliaxis, Corominas, Jordi, Estelle, Jordi, Perez-Montarelo, Dafne, Hudson, Nicholas J., Casellas, Joaquim, Folch, Josep M. and Ballester, Maria (2014). Differences in muscle transcriptome among pigs phenotypically extreme for fatty acid composition. PLoS ONE, 9 (6) e99720, e99720. doi: 10.1371/journal.pone.0099720

Differences in muscle transcriptome among pigs phenotypically extreme for fatty acid composition

2014

Journal Article

RNF14 is a regulator of mitochondrial and immune function in muscle

Ingham, Aaron B., Osborne, Simone A., Menzies, Moira, Briscoe, Suzie, Chen, Wei, Kongsuwan, Kritaya, Reverter, Antonio, Jeanes, Angela, Dalrymple, Brian P., Wijffels, Gene, Seymour, Robert and Hudson, Nicholas J. (2014). RNF14 is a regulator of mitochondrial and immune function in muscle. BMC Systems Biology, 8 (1) 10, 1-12. doi: 10.1186/1752-0509-8-10

RNF14 is a regulator of mitochondrial and immune function in muscle

2013

Journal Article

Gene expression phenotypes for lipid metabolism and intramuscular fat in skeletal muscle of cattle

De Jager, N., Hudson, N. J., Reverter, A., Barnard, R., Cafe, L. M., Greenwood, P. L. and Dalrymple, B. P. (2013). Gene expression phenotypes for lipid metabolism and intramuscular fat in skeletal muscle of cattle. Journal of Animal Science, 91 (3), 1112-1128. doi: 10.2527/jas2012-5409

Gene expression phenotypes for lipid metabolism and intramuscular fat in skeletal muscle of cattle

2013

Journal Article

Inferring the in vivo cellular program of developing bovine skeletal muscle from expression data

Hudson, Nicholas J., Lyons, Russell E., Reverter, Antonio, Greenwood, Paul L. and Dalrymple, Brian P. (2013). Inferring the in vivo cellular program of developing bovine skeletal muscle from expression data. Gene Expression Patterns, 13 (3-4), 109-125. doi: 10.1016/j.gep.2013.02.001

Inferring the in vivo cellular program of developing bovine skeletal muscle from expression data

Funding

Current funding

  • 2022 - 2026
    LESTR Low Emission Saliva Test for Ruminants
    Meat & Livestock Australia
    Open grant
  • 2019 - 2025
    How do brains become lateralised? (ARC Discovery Project administered by Macquarie University)
    Macquarie University
    Open grant

Past funding

  • 2023 - 2024
    Innate immune response to Ross River virus infection in horses
    Research Donation Generic
    Open grant
  • 2019 - 2020
    Understanding the Mechanisms of West Nile virus (WNV) induced lesions in the Australian saltwater crocodile (Crocodylus porosus)
    Research Donation Generic
    Open grant
  • 2019 - 2022
    Increased pasture intake and reduced supplement requirements of sheep/cattle
    Meat & Livestock Australia
    Open grant
  • 2018 - 2020
    The gateway to selecting for nutrient efficient livestock - ''Better doers'' (Meat and Livestock Australia grant administered by NSW Department of Primary Industries)
    New South Wales Department of Primary Industries
    Open grant
  • 2017
    Towards a high-throughput metabolic phenotyping capability for production animals and plants
    UQ Major Equipment and Infrastructure
    Open grant

Supervision

Availability

Dr Nick Hudson is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Mitochondria and livestock feed efficiency

    Some production animals utilise feed more efficiently for production than others, while some are able to maintain muscle mass, liveweight and productivity under periods of nutritional and environmental stress.

    Why is this? The successful applicant will focus their research on the biology of the mitochondria and its role in determining metabolic efficiency in cattle.

  • Frog and butterfly ecology

    Projects regarding the fundamental biology and ecology of both frogs and butterflies are available.

    Fieldwork will be based at Hiddenvale Research Station (https://hiddenvalewildlife.uq.edu.au/). There is a lot of scope for flexibility in project development so if you have any ideas - or even just a passion for - these two groups of animals please get in touch.

  • Metabolism across species

    Are you interested in growth, development and metabolism? Students are encouraged to get in touch with any of their own ideas in the broad area of animal biology. Projects can be developed collaboratively with other academics within and beyond AGFS so there is lots of scope for diversity and inter-disciplinary research.

    We encourage students to develope their own ideas and projects. In our lab we use a range of metabolic and molecular tools such as gene expression, metabolic flux analysis and SNP genotyping that can be readily applied across species and biological circumstances.

    You can learn how to handle and quantitate DNA and RNA, run an agarose gel, estimate gene expression by quantitative PCR and phenotype animal and plant cells in the state of the art XFe24 Flux analyser.

    Remember, a new discovery is just round the corner!

  • The interface between genomes and diet in ruminant farm animals

    Livestock products provide a nutritious source of protein (and a range of other molecules including bioavailable iron and vitamin B12). More efficient production may be required to meet not only increasing demand but also greater awareness over welfare issues and environmental footprint.

    Breeds and individual cattle and sheep can show substantial differences in how they respond to diets, with some animals more productive than others. The proposed research will investigate which parts of the genome underpin productivity in cattle and sheep.

    Biochemical pathways relevant to the new science of nutrigenomics will be uncovered primarily through investigation of genome-wide gene expression data sets available for metabolically important tissues such as muscle, fat and liver.

    Cutting edge bioinformatics tools including the latest approaches from network science will be deployed. This knowledge may help us understand why some animals fare better than others under given nutritional circumstances and perhaps inform decisions regarding diet formulation.

Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Dr Nick Hudson directly for media enquiries about:

  • feed efficiency
  • flux analysis
  • functional genomics
  • mitochondria
  • muscle growth
  • production animals

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au