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Dr Nick Hudson
Dr

Nick Hudson

Email: 
Phone: 
+61 7 54601 521

Overview

Background

Nick is interested in fostering efficient, environmentally friendly animal production enterprises. He uses the data and capabilities provided by modern 'omics technologies to help improve breeding decisions and to inform other types of 'on farm' intervention.

Nick has a parallel interest in the development, physiology, metabolism and conservation of native Australian species, particularly frogs and butterflies.

Nick is a metabolic biochemist by training with research expertise in a) the handling and biological interpretation of large, complex data sets b) molecular technologies c) mitochondrial physiology and d) metabolic flux.

Nick enjoys teaching various aspects of biochemistry and molecular biology to both undergraduate and postgraduate students. He highlights the main themes using the comparative method and illustrates their importance through applied examples from agriculture and other areas of human endeavour.

Before taking his current position as a Teaching and Research academic in the School of Agriculture and Food Sustainability (AGFS) Nick worked for the CSIRO in a research intensive multi-disciplinary Systems Biology group.

Through this group he helped develop and apply bioinformatic methods that used metabolite, protein, RNA and DNA biotech to understand, model and predict phenotypes of commercial importance in cattle, sheep, pigs and chickens.

A research highlight from this time was the co-invention of a universal method for inferring causal molecules from genome-wide gene expression data (Hudson et al 2009. PLoS Comp Biol e1000382). This method has been applied across a diverse range of model systems including human kidney cancer and commercial traits in various agricultural species.

Following an undergraduate degree in Animal Biology at the University of St.Andrews, Nick was awarded his PhD through what was then the Zoology department of the University of Queensland, after travelling from England on a Britain-Australia Society funded Northcote Scholarship.

Availability

Dr Nick Hudson is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, The University of Queensland

Research interests

  • Productive, efficient farm animals

  • Wildlife biology of butterflies and frogs

  • Mitochondrial physiology

  • Metabolism

  • Flux analysis

  • Agricultural resource utilisation

Research impacts

Nick is an active science communicator whose research has been disseminated through print, radio and television media.

He hopes to make an impact on agricultural resource utilisation through a better understanding of production animal feed efficiency, and to sustainable agriculture through an understanding of agro-ecology and wildlife biology.

Nick has a very active national and international network of collaborators from academe, government agencies and industry.

This collaborative network has provided stimulating insights into industrial problems and how novel technologies and innovative concepts may inspire creative solutions.

Works

Search Professor Nick Hudson’s works on UQ eSpace

91 works between 2000 and 2024

81 - 91 of 91 works

2006

Journal Article

Gene expression profiling of bovine skeletal muscle in response to and during recovery from chronic and severe undernutrition

Lehnert, S. A., Byrne, K. A., Reverter, A., Nattrass, G. S., Greenwood, P. L., Wang, Y. H., Hudson, N. J. and Harper, G. S. (2006). Gene expression profiling of bovine skeletal muscle in response to and during recovery from chronic and severe undernutrition. Journal of Animal Science, 84 (12), 3239-3250. doi: 10.2527/jas.2006-192

Gene expression profiling of bovine skeletal muscle in response to and during recovery from chronic and severe undernutrition

2006

Journal Article

Lessons from an estivating frog: sparing muscle protein despite starvation and disuse

Hudson, N. J., Lehnert, S. A., Ingham, A. B., Symonds, B., Franklin, C. E. and Harper, G. S. (2006). Lessons from an estivating frog: sparing muscle protein despite starvation and disuse. American Journal of Physiology-regulatory Integrative And Comparative Physiology, 290 (3), R836-R843. doi: 10.1152/ajpregu.00380.2005

Lessons from an estivating frog: sparing muscle protein despite starvation and disuse

2005

Journal Article

Validation of alternative methods of data normalization in gene co-expression studies

Reverter, A, Barris, W, McWilliam, S, Byrne, KA, Wang, YH, Tan, SH, Hudson, N and Dalrymple, BP (2005). Validation of alternative methods of data normalization in gene co-expression studies. Bioinformatics, 21 (7), 1112-1120. doi: 10.1093/bioinformatics/bti124

Validation of alternative methods of data normalization in gene co-expression studies

2005

Journal Article

Effect of prolonged inactivity on skeletal motor nerve terminals during aestivation in the burrowing frog, Cyclorana alboguttata

Hudson, N. J., Lavidis, N. A., Choy, P. T. and Franklin, C. E. (2005). Effect of prolonged inactivity on skeletal motor nerve terminals during aestivation in the burrowing frog, Cyclorana alboguttata. Journal of Comparative Physiology A-neuroethology Sensory Neural And Behavioral Physiology, 191 (4), 373-379. doi: 10.1007/s00359-004-0593-5

Effect of prolonged inactivity on skeletal motor nerve terminals during aestivation in the burrowing frog, Cyclorana alboguttata

2004

Journal Article

Effect of aestivation on long bone mechanical properties in the green-striped burrowing frog, Cyclorana alboguttata

Hudson, N. J., Bennett, M. B. and Franklin, C. E. (2004). Effect of aestivation on long bone mechanical properties in the green-striped burrowing frog, Cyclorana alboguttata. Journal of Experimental Biology, 207 (3), 475-482. doi: 10.1242/jeb.00787

Effect of aestivation on long bone mechanical properties in the green-striped burrowing frog, Cyclorana alboguttata

2004

Conference Publication

Modulation of transmitter release from neuromuscular terminals of green striped burrowing frog, Cyclorana alboguttata

Choy, P. T., Lan, M., Hudson, N. J., Franklin, C. and Lavidis, N. A. (2004). Modulation of transmitter release from neuromuscular terminals of green striped burrowing frog, Cyclorana alboguttata. Society for Neuroscience 34th Annual Meeting, San Diego, United States, 23–27 October 2004. San Diego, United States:

Modulation of transmitter release from neuromuscular terminals of green striped burrowing frog, Cyclorana alboguttata

2003

Journal Article

Preservation of three-dimensional capillary structure in frog muscle during aestivation

Hudson, Nicholas J. and Franklin, Craig E. (2003). Preservation of three-dimensional capillary structure in frog muscle during aestivation. Journal of Anatomy, 202 (5), 471-474. doi: 10.1046/j.1469-7580.2003.00178.x

Preservation of three-dimensional capillary structure in frog muscle during aestivation

2003

Other Outputs

The effect of aestivation on the musculo-skeletal system of the green striped burrowing frog, Cyclorana alboguttata

Hudson, Nicholas J. (2003). The effect of aestivation on the musculo-skeletal system of the green striped burrowing frog, Cyclorana alboguttata. PhD Thesis, School of Integrative Biology, The University of Queensland. doi: 10.14264/106234

The effect of aestivation on the musculo-skeletal system of the green striped burrowing frog, Cyclorana alboguttata

2002

Journal Article

Effect of aestivation on muscle characteristics and locomotor performance in the Green-striped burrowing frog, Cyclorana alboguttata

Hudson, N. J. and Franklin, C. E. (2002). Effect of aestivation on muscle characteristics and locomotor performance in the Green-striped burrowing frog, Cyclorana alboguttata. Journal of Comparative Physiology B-biochemical Systemic And Environmental Physiology, 172 (2), 177-182. doi: 10.1007/s00360-001-0242-z

Effect of aestivation on muscle characteristics and locomotor performance in the Green-striped burrowing frog, Cyclorana alboguttata

2002

Journal Article

Maintaining muscle mass during extended disuse: aestivating frogs as a model species

Hudson, Nicholas J. and Franklin, Craig E. (2002). Maintaining muscle mass during extended disuse: aestivating frogs as a model species. Journal of Experimental Biology, 205 (15), 2297-2303. doi: 10.1242/jeb.205.15.2297

Maintaining muscle mass during extended disuse: aestivating frogs as a model species

2000

Conference Publication

Waking up from aestivation in the green striped burrowing frog

Franklin, C. E., Hudson, N. and Cramp, R. L. (2000). Waking up from aestivation in the green striped burrowing frog. Experimental Biology 2000- Milestones and Goals, Cambridge, United Kingdom, 30 July - 3 August 2000. New York, NY United States: Elsevier.

Waking up from aestivation in the green striped burrowing frog

Funding

Current funding

  • 2023 - 2024
    Innate immune response to Ross River virus infection in horses
    Research Donation Generic
    Open grant
  • 2022 - 2026
    LESTR Low Emission Saliva Test for Ruminants
    Meat & Livestock Australia
    Open grant

Past funding

  • 2019 - 2020
    Understanding the Mechanisms of West Nile virus (WNV) induced lesions in the Australian saltwater crocodile (Crocodylus porosus)
    Research Donation Generic
    Open grant
  • 2019 - 2022
    How do brains become lateralised? (ARC Discovery Project administered by Macquarie University)
    Macquarie University
    Open grant
  • 2019 - 2022
    Increased pasture intake and reduced supplement requirements of sheep/cattle
    Meat & Livestock Australia
    Open grant
  • 2018 - 2020
    The gateway to selecting for nutrient efficient livestock - ''Better doers'' (Meat and Livestock Australia grant administered by NSW Department of Primary Industries)
    New South Wales Department of Primary Industries
    Open grant
  • 2017
    Towards a high-throughput metabolic phenotyping capability for production animals and plants
    UQ Major Equipment and Infrastructure
    Open grant

Supervision

Availability

Dr Nick Hudson is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Mitochondria and livestock feed efficiency

    Some production animals utilise feed more efficiently for production than others, while some are able to maintain muscle mass, liveweight and productivity under periods of nutritional and environmental stress.

    Why is this? The successful applicant will focus their research on the biology of the mitochondria and its role in determining metabolic efficiency in cattle.

  • Frog and butterfly ecology

    Projects regarding the fundamental biology and ecology of both frogs and butterflies are available.

    Fieldwork will be based at Hiddenvale Research Station (https://hiddenvalewildlife.uq.edu.au/). There is a lot of scope for flexibility in project development so if you have any ideas - or even just a passion for - these two groups of animals please get in touch.

  • Metabolism across species

    Are you interested in growth, development and metabolism? Students are encouraged to get in touch with any of their own ideas in the broad area of animal biology. Projects can be developed collaboratively with other academics within and beyond AGFS so there is lots of scope for diversity and inter-disciplinary research.

    We encourage students to develope their own ideas and projects. In our lab we use a range of metabolic and molecular tools such as gene expression, metabolic flux analysis and SNP genotyping that can be readily applied across species and biological circumstances.

    You can learn how to handle and quantitate DNA and RNA, run an agarose gel, estimate gene expression by quantitative PCR and phenotype animal and plant cells in the state of the art XFe24 Flux analyser.

    Remember, a new discovery is just round the corner!

  • The interface between genomes and diet in ruminant farm animals

    Livestock products provide a nutritious source of protein (and a range of other molecules including bioavailable iron and vitamin B12). More efficient production may be required to meet not only increasing demand but also greater awareness over welfare issues and environmental footprint.

    Breeds and individual cattle and sheep can show substantial differences in how they respond to diets, with some animals more productive than others. The proposed research will investigate which parts of the genome underpin productivity in cattle and sheep.

    Biochemical pathways relevant to the new science of nutrigenomics will be uncovered primarily through investigation of genome-wide gene expression data sets available for metabolically important tissues such as muscle, fat and liver.

    Cutting edge bioinformatics tools including the latest approaches from network science will be deployed. This knowledge may help us understand why some animals fare better than others under given nutritional circumstances and perhaps inform decisions regarding diet formulation.

Supervision history

Current supervision

  • Doctor Philosophy

    Cellular oxidative damage and ruminant feed efficiency

    Principal Advisor

    Other advisors: Associate Professor Marina Fortes

  • Doctor Philosophy

    Using Systems Biology to understand the genetic basis of bull fertility phenotypes and their covariance

    Associate Advisor

    Other advisors: Associate Professor Marina Fortes

Completed supervision

Media

Enquiries

Contact Dr Nick Hudson directly for media enquiries about:

  • feed efficiency
  • flux analysis
  • functional genomics
  • mitochondria
  • muscle growth
  • production animals

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au