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Dr Nick Hudson
Dr

Nick Hudson

Email: 
Phone: 
+61 7 54601 521

Overview

Background

Nick’s research focuses on improving the efficiency and environmental sustainability of animal production systems. He uses modern omics technologies and quantitative analysis to support genetic improvement, inform management decisions, and enhance on-farm interventions that improve productivity while reducing environmental impact.

In parallel, he studies the physiology, metabolism and conservation of native Australian fauna, with particular interest in frogs and butterflies. His work applies comparative and systems-based approaches to understand how animals function across diverse ecological contexts.

Trained as a metabolic biochemist, Nick’s expertise spans the interpretation of large and complex biological datasets, molecular technologies, mitochondrial physiology, and metabolic flux. His research integrates molecular data with whole-animal function to better understand how biological systems convert energy and information into phenotypic outcomes.

Before joining the School of Agriculture and Food Sustainability (AGFS) as a Teaching and Research academic, Nick worked within a multidisciplinary Systems Biology group at CSIRO. There he helped develop and apply bioinformatic approaches that integrate metabolite, protein, RNA and DNA data to model and predict phenotypes of commercial importance in cattle, sheep, pigs and poultry.

A highlight of this work was the co-development of a universal method for inferring causal regulatory molecules from genome-wide gene expression data (Hudson et al., 2009, PLoS Computational Biology). This approach has since been applied across diverse systems, including human kidney cancer and commercially important traits in livestock species.

Nick’s broader research contributions reflect an interest in complex biological function across scales. His publications have addressed mitochondrial systems biology, metabolic adaptation and hibernation physiology, population genetics methodology, and the physiological basis of economically important traits such as beef marbling and feed conversion efficiency. He has also contributed to interdisciplinary work exploring information processing in biological and cognitive systems and the interpretation of educational data.

Nick completed his undergraduate degree in Animal Biology at the University of St Andrews and was awarded his PhD through the Zoology Department at The University of Queensland after travelling from England on a Britain–Australia Society Northcote Scholarship.

He teaches biochemistry and molecular biology to undergraduate and postgraduate students using a comparative approach that draws on both wildlife and production species. Core biochemical principles are illustrated through applied examples from agriculture, biomedicine, sports science and environmental systems, helping students understand how molecular processes scale to whole-organism function and real-world outcomes.

Availability

Dr Nick Hudson is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, The University of Queensland

Research interests

  • Productive, efficient farm animals

  • Wildlife biology of butterflies and frogs

  • Mitochondrial physiology

  • Metabolism

  • Flux analysis

  • Agricultural resource utilisation

Research impacts

Nick is an active science communicator whose research has been disseminated through print, radio and television media.

He hopes to make an impact on agricultural resource utilisation through a better understanding of production animal feed efficiency, and to sustainable agriculture through an understanding of agro-ecology and wildlife biology.

Nick has a very active national and international network of collaborators from academe, government agencies and industry.

This collaborative network has provided stimulating insights into industrial problems and how novel technologies and innovative concepts may inspire creative solutions.

Works

Search Professor Nick Hudson’s works on UQ eSpace

97 works between 2000 and 2025

61 - 80 of 97 works

2013

Journal Article

Gene expression phenotypes for lipid metabolism and intramuscular fat in skeletal muscle of cattle

De Jager, N., Hudson, N. J., Reverter, A., Barnard, R., Cafe, L. M., Greenwood, P. L. and Dalrymple, B. P. (2013). Gene expression phenotypes for lipid metabolism and intramuscular fat in skeletal muscle of cattle. Journal of Animal Science, 91 (3), 1112-1128. doi: 10.2527/jas2012-5409

Gene expression phenotypes for lipid metabolism and intramuscular fat in skeletal muscle of cattle

2013

Journal Article

Effect of opioids on tissue metabolism in aestivating and active Green-Striped Burrowing Frogs, Cyclorana alboguttata

Kayes, Sara M., Cramp, Rebecca L., Hudson, Nicholas J. and Franklin, Craig E. (2013). Effect of opioids on tissue metabolism in aestivating and active Green-Striped Burrowing Frogs, Cyclorana alboguttata. Journal of Herpetology, 47 (2), 369-377. doi: 10.1670/12-039

Effect of opioids on tissue metabolism in aestivating and active Green-Striped Burrowing Frogs, Cyclorana alboguttata

2012

Journal Article

An Always Correlated gene expression landscape for ovine skeletal muscle, lessons learnt from comparison with an "equivalent" bovine landscape

Sun, Wei, Hudson, Nicholas J., Reverter, Antonio, Waardenberg, Ashley J., Tellam, Ross L., Vuocolo, Tony, Byrne, Keren and Dalrymple, Brian P. (2012). An Always Correlated gene expression landscape for ovine skeletal muscle, lessons learnt from comparison with an "equivalent" bovine landscape. BMC Research Notes, 5 (1) 632. doi: 10.1186/1756-0500-5-632

An Always Correlated gene expression landscape for ovine skeletal muscle, lessons learnt from comparison with an "equivalent" bovine landscape

2012

Journal Article

Porcine tissue-specific regulatory networks derived from meta-analysis of the transcriptome

Perez-Montarelo, Dafne, Hudson, Nicholas J., Fernandez, Ana I., Ramayo-Caldas, Yuliaxis, Dalrymple, Brian P. and Reverter, Antonio (2012). Porcine tissue-specific regulatory networks derived from meta-analysis of the transcriptome. PLoS ONE, 7 (9) e46159, e46159. doi: 10.1371/journal.pone.0046159

Porcine tissue-specific regulatory networks derived from meta-analysis of the transcriptome

2012

Journal Article

Mitochondrial treason: a driver of pH decline rate in post-mortem muscle?

Hudson, Nicholas J. (2012). Mitochondrial treason: a driver of pH decline rate in post-mortem muscle?. Animal Production Science, 52 (12), 1107-1110. doi: 10.1071/AN12171

Mitochondrial treason: a driver of pH decline rate in post-mortem muscle?

2012

Journal Article

Beyond differential expression: the quest for causal mutations and effector molecules

Hudson, Nicholas J., Dalrymple, Brian P. and Reverter, Antonio (2012). Beyond differential expression: the quest for causal mutations and effector molecules. BMC Genomics, 13 (1) 356. doi: 10.1186/1471-2164-13-356

Beyond differential expression: the quest for causal mutations and effector molecules

2011

Journal Article

Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins

Hudson, Nicholas J., Gu, Quan, Nagaraj, Shivashankar H., Ding, Yong-Sheng, Dalrymple, Brian P. and Reverter, Antonio (2011). Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins. PLoS ONE, 6 (9) e25457, e25457. doi: 10.1371/journal.pone.0025457

Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins

2011

Journal Article

Chronic exposure to anabolic steroids induces the muscle expression of oxytocin and a more than fiftyfold increase in circulating oxytocin in cattle

De Jager, Nadia, Hudson, Nicolas J., Reverter, Antonio, Wang, Yong-Hong, Nagaraj, Shivashankar H., Cafe, Linda M., Greenwood, Paul L., Barnard, Ross T., Kongsuwan, Kritaya P. and Dalrymple, Brian P. (2011). Chronic exposure to anabolic steroids induces the muscle expression of oxytocin and a more than fiftyfold increase in circulating oxytocin in cattle. Physiological Genomics, 43 (9), 467-478. doi: 10.1152/physiolgenomics.00226.2010

Chronic exposure to anabolic steroids induces the muscle expression of oxytocin and a more than fiftyfold increase in circulating oxytocin in cattle

2011

Journal Article

Musical beauty and information compression: complex to the ear but simple to the mind?

Hudson, Nicholas J. (2011). Musical beauty and information compression: complex to the ear but simple to the mind?. BMC Research Notes, 4 (1) 9. doi: 10.1186/1756-0500-4-9

Musical beauty and information compression: complex to the ear but simple to the mind?

2011

Journal Article

Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle

Gu, Quan, Nagaraj, Shivashankar H., Hudson, Nicholas J., Dalrymple, Brian P. and Reverter, Antonio (2011). Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle. BMC Genomics, 12 (1) 23, 23.1-23.13. doi: 10.1186/1471-2164-12-23

Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle

2010

Journal Article

Enzyme activity in the aestivating Green-striped burrowing frog (Cyclorana alboguttata)

Mantle, Beth L., Guderley, Helga, Hudson, Nicholas J. and Franklin, Craig E. (2010). Enzyme activity in the aestivating Green-striped burrowing frog (Cyclorana alboguttata). Journal of Comparative Physiology B-biochemical Systemic And Environmental Physiology, 180 (7), 1033-1043. doi: 10.1007/s00360-010-0471-0

Enzyme activity in the aestivating Green-striped burrowing frog (Cyclorana alboguttata)

2010

Journal Article

Activity, abundance, distribution and expression of Na+/K+-ATPase in the salt glands of Crocodylus porosus following chronic saltwater acclimation

Cramp, Rebecca L., Hudson, Nicholas J. and Franklin, Craig E. (2010). Activity, abundance, distribution and expression of Na+/K+-ATPase in the salt glands of Crocodylus porosus following chronic saltwater acclimation. Journal of Experimental Biology, 213 (8), 1301-1308. doi: 10.1242/jeb.039305

Activity, abundance, distribution and expression of Na+/K+-ATPase in the salt glands of Crocodylus porosus following chronic saltwater acclimation

2010

Journal Article

Regulatory impact factors: unraveling the transcriptional regulation of complex traits from expression data

Reverter, Antonio, Hudson, Nicholas J., Nagaraj, Shivashankar H., Perez-Enciso, Miguel and Dalrymple, Brian P. (2010). Regulatory impact factors: unraveling the transcriptional regulation of complex traits from expression data. Bioinformatics, 26 (7) btq051, 896-904. doi: 10.1093/bioinformatics/btq051

Regulatory impact factors: unraveling the transcriptional regulation of complex traits from expression data

2009

Journal Article

Skeletal muscle atrophy occurs slowly and selectively during prolonged aestivation in Cyclorana alboguttata (Gunther 1867)

Mantle, Beth L., Hudson, Nicholas J., Harper, Gregory S., Cramp, Rebecca L. and Franklin, Craig E. (2009). Skeletal muscle atrophy occurs slowly and selectively during prolonged aestivation in Cyclorana alboguttata (Gunther 1867). Journal of Experimental Biology, 212 (22), 3664-3672. doi: 10.1242/jeb.033688

Skeletal muscle atrophy occurs slowly and selectively during prolonged aestivation in Cyclorana alboguttata (Gunther 1867)

2009

Journal Article

Inferring the transcriptional landscape of bovine skeletal muscle by integrating co-expression networks

Hudson, Nicholas J., Reverter, Antonio, Wang, YongHong, Greenwood, Paul L. and Dalrymple, Brian P. (2009). Inferring the transcriptional landscape of bovine skeletal muscle by integrating co-expression networks. PLoS ONE, 4 (10) e7249, e7249. doi: 10.1371/journal.pone.0007249

Inferring the transcriptional landscape of bovine skeletal muscle by integrating co-expression networks

2009

Journal Article

Surviving the drought: Burrowing frogs save energy by increasing mitochondrial coupling

Kayes, Sara M., Cramp, Rebecca L., Hudson, Nicholas J. and Franklin, Craig E. (2009). Surviving the drought: Burrowing frogs save energy by increasing mitochondrial coupling. Journal of Experimental Biology, 212 (14), 2248-2253. doi: 10.1242/jeb.028233

Surviving the drought: Burrowing frogs save energy by increasing mitochondrial coupling

2009

Journal Article

Symmorphosis and livestock bioenergetics: production animal muscle has low mitochondrial volume fractions

Hudson, Nicholas J. (2009). Symmorphosis and livestock bioenergetics: production animal muscle has low mitochondrial volume fractions. Journal of Animal Physiology and Animal Nutrition, 93 (1), 1-6. doi: 10.1111/j.1439-0396.2007.00791.x

Symmorphosis and livestock bioenergetics: production animal muscle has low mitochondrial volume fractions

2009

Conference Publication

Burrowing frog metabolism: maximising energy savings during dormancy

Kayes, Sara M., Cramp, Rebecca L., Hudson, Nicholas J. and Franklin, Craig E. (2009). Burrowing frog metabolism: maximising energy savings during dormancy. Annual Meeting of the Society for Experimental Biology, Glasgow Scotland, 28June-01 July 2009. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.cbpa.2009.04.126

Burrowing frog metabolism: maximising energy savings during dormancy

2008

Journal Article

Epigenetic silencers are enriched in dormant desert frog muscle

Hudson, Nicholas J., Lonhienne, T. G. A,, Franklin, Craig E., Harper, Gregory S. and Lehnert, S. A. (2008). Epigenetic silencers are enriched in dormant desert frog muscle. Journal of Comparative Physiology B Biochemical, Systems, and Environmental Physiology, 178 (6), 729-734. doi: 10.1007/s00360-008-0261-0

Epigenetic silencers are enriched in dormant desert frog muscle

2008

Conference Publication

Opioids as triggers for metabolic depression in the frog, Cyclorana alboguttata

Kayes, S., Hudson, N. and Franklin, C. (2008). Opioids as triggers for metabolic depression in the frog, Cyclorana alboguttata. Annual Meeting of the Society-for-Experimental-Biology, Marseille, France, 6-10 July, 2008. New York, U.S.: Elsevier. doi: 10.1016/j.cbpa.2008.04.202

Opioids as triggers for metabolic depression in the frog, Cyclorana alboguttata

Funding

Current funding

  • 2022 - 2026
    LESTR Low Emission Saliva Test for Ruminants
    Meat & Livestock Australia
    Open grant

Past funding

  • 2023 - 2024
    Innate immune response to Ross River virus infection in horses
    Research Donation Generic
    Open grant
  • 2019 - 2020
    Understanding the Mechanisms of West Nile virus (WNV) induced lesions in the Australian saltwater crocodile (Crocodylus porosus)
    Research Donation Generic
    Open grant
  • 2019 - 2025
    How do brains become lateralised? (ARC Discovery Project administered by Macquarie University)
    Macquarie University
    Open grant
  • 2019 - 2022
    Increased pasture intake and reduced supplement requirements of sheep/cattle
    Meat & Livestock Australia
    Open grant
  • 2018 - 2020
    The gateway to selecting for nutrient efficient livestock - ''Better doers'' (Meat and Livestock Australia grant administered by NSW Department of Primary Industries)
    New South Wales Department of Primary Industries
    Open grant
  • 2017
    Towards a high-throughput metabolic phenotyping capability for production animals and plants
    UQ Major Equipment and Infrastructure
    Open grant

Supervision

Availability

Dr Nick Hudson is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Available projects

  • Mitochondria and livestock feed efficiency

    Some production animals utilise feed more efficiently for production than others, while some are able to maintain muscle mass, liveweight and productivity under periods of nutritional and environmental stress.

    Why is this? The successful applicant will focus their research on the biology of the mitochondria and its role in determining metabolic efficiency in cattle.

  • Frog and butterfly ecology

    Projects regarding the fundamental biology and ecology of both frogs and butterflies are available.

    Fieldwork will be based at Hiddenvale Research Station (https://hiddenvalewildlife.uq.edu.au/). There is a lot of scope for flexibility in project development so if you have any ideas - or even just a passion for - these two groups of animals please get in touch.

  • Metabolism across species

    Are you interested in growth, development and metabolism? Students are encouraged to get in touch with any of their own ideas in the broad area of animal biology. Projects can be developed collaboratively with other academics within and beyond AGFS so there is lots of scope for diversity and inter-disciplinary research.

    We encourage students to develope their own ideas and projects. In our lab we use a range of metabolic and molecular tools such as gene expression, metabolic flux analysis and SNP genotyping that can be readily applied across species and biological circumstances.

    You can learn how to handle and quantitate DNA and RNA, run an agarose gel, estimate gene expression by quantitative PCR and phenotype animal and plant cells in the state of the art XFe24 Flux analyser.

    Remember, a new discovery is just round the corner!

  • The interface between genomes and diet in ruminant farm animals

    Livestock products provide a nutritious source of protein (and a range of other molecules including bioavailable iron and vitamin B12). More efficient production may be required to meet not only increasing demand but also greater awareness over welfare issues and environmental footprint.

    Breeds and individual cattle and sheep can show substantial differences in how they respond to diets, with some animals more productive than others. The proposed research will investigate which parts of the genome underpin productivity in cattle and sheep.

    Biochemical pathways relevant to the new science of nutrigenomics will be uncovered primarily through investigation of genome-wide gene expression data sets available for metabolically important tissues such as muscle, fat and liver.

    Cutting edge bioinformatics tools including the latest approaches from network science will be deployed. This knowledge may help us understand why some animals fare better than others under given nutritional circumstances and perhaps inform decisions regarding diet formulation.

Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Dr Nick Hudson directly for media enquiries about:

  • feed efficiency
  • flux analysis
  • functional genomics
  • mitochondria
  • muscle growth
  • production animals

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au