
Overview
Background
Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 300 peer-reviewed articles, 60 conference abstracts, 14 book chapters and has delivered over 100 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.
Availability
- Professor Kiran Shekar is:
- Available for supervision
- Media expert
Research interests
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Extracorporeal membrane oxygenation
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Respiratory failure and minimising the burden of invasive mechanical ventilation
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PK/PD on Extracorporeal membrane oxygenation support
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Cardiogenic Shock and Mechanical Circulatory Support
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Microcirculation on temporary Mechanical Circulatory Support
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Building a budget intensive care unit to improve intensive care access in resource poor countries
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Standardising ECMO education to bridge the variability in global ECMO outcomes
Works
Search Professor Kiran Shekar’s works on UQ eSpace
2024
Journal Article
Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study
Ling, Ryan Ruiyang, Ponnapa Reddy, Mallikarjuna, Subramaniam, Ashwin, Moran, Benjamin, Ramanathan, Kollengode, Ramanan, Mahesh, Burrell, Aidan, Pilcher, David and Shekar, Kiran (2024). Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study. Intensive Care Medicine, 50 (11), 1861-1872. doi: 10.1007/s00134-024-07609-y
2024
Journal Article
Post-cardiotomy extracorporeal life support: a cohort of cannulation in the general ward
Bari, Gabor, Mariani, Silvia, van Bussel, Bas C. T., Ravaux, Justine, Di Mauro, Michele, Schaefer, Anne, Khalil, Jawad, Pozzi, Matteo, Botta, Luca, Pacini, Davide, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Bunge, Jeroen J. H., Buscher, Hergen, Salazar, Leonardo, Meyns, Bart, Mazeffi, Michael, Matteucci, Sacha, Sponga, Sandro, MacLaren, Graeme, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo ... Lorusso, Roberto (2024). Post-cardiotomy extracorporeal life support: a cohort of cannulation in the general ward. Artificial Organs, 48 (11), 1355-1365. doi: 10.1111/aor.14818
2024
Journal Article
Hypothermia and Influence of Rewarming Rates on Survival Among Patients Admitted to Intensive Care with Bloodstream Infection: A Multicenter Cohort Study
White, Kyle C., Quick, Lachlan, Ramanan, Mahesh, Tabah, Alexis, Shekar, Kiran, Senthuran, Siva, Edwards, Felicity, Attokaran, Antony G., Kumar, Aashish, Meyer, Jason, McCullough, James, Blank, Sebastiaan, Smart, Christopher, Garrett, Peter, Laupland, Kevin B. and on behalf of the Queensland Critical Care Research Network (QCCRN) (2024). Hypothermia and Influence of Rewarming Rates on Survival Among Patients Admitted to Intensive Care with Bloodstream Infection: A Multicenter Cohort Study. Therapeutic Hypothermia and Temperature Management, 15 (3), 1-6. doi: 10.1089/ther.2024.0047
2024
Journal Article
Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation (vol 50, pg 1470, 2024)
Burrell, Aidan, Bailey, Michael J., Bellomo, Rinaldo, Buscher, Hergen, Eastwood, Glenn, Forrest, Paul, Fraser, John F., Fulcher, Bentley, Gattas, David, Higgins, Alisa M., Hodgson, Carol L., Litton, Edward, Martin, Emma-Leah, Nair, Priya, Ng, Sze J., Orford, Neil, Ottosen, Kelly, Paul, Eldho, Pellegrino, Vincent, Reid, Liadain, Shekar, Kiran, Totaro, Richard J., Trapani, Tony, Udy, Andrew, Ziegenfuss, Marc, Pilcher, David and on behalf of The BLENDER Trial Investigators, EXCEL Registry, ECMONet and the Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group and Centre for Outcomes and Resource Evaluation (2024). Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation (vol 50, pg 1470, 2024). Intensive Care Medicine, 50 (12), 2241-2242. doi: 10.1007/s00134-024-07677-0
2024
Journal Article
ECMO: more than just a bridge over troubled waters?
Ling, Ryan Ruiyang, Ramanathan, Kollengode and Shekar, Kiran (2024). ECMO: more than just a bridge over troubled waters?. The Lancet Respiratory Medicine, 12 (10), 756-758. doi: 10.1016/s2213-2600(24)00261-3
2024
Journal Article
Definitions of adverse events associated with extracorporeal membrane oxygenation in children: results of an international Delphi process from the ECMO-CENTRAL ARC
Alexander, Peta M. A., Di Nardo, Matteo, Combes, Alain, Vogel, Adam M, Antonini, Marta Velia, Barrett, Nicholas, Benedetti, Giulia M, Bettencourt, Amanda, Brodie, Daniel, Gómez-Gutiérrez, René, Gorga, Stephen M., Hodgson, Carol, Kapoor, Poonam Malhotra, Le, Jennifer, MacLaren, Graeme, O'Neil, Erika R., Ostermann, Marlies, Paden, Matthew L., Patel, Neil, Rojas-Peña, Alvaro, Said, Ahmed S., Sperotto, Francesca, Willems, Ariane, Vercaemst, Leen, Yoganathan, Ajit P., Lorts, Angela, del Nido, Pedro J., Barbaro, Ryan P., Abecasis, Francisco ... Society of Thoracic Surgeons (STS), Society of Critical Care Medicine (SCCM) (2024). Definitions of adverse events associated with extracorporeal membrane oxygenation in children: results of an international Delphi process from the ECMO-CENTRAL ARC. The Lancet Child and Adolescent Health, 8 (10), 773-780. doi: 10.1016/S2352-4642(24)00132-9
2024
Journal Article
Epidemiology of hypophosphatemia in critical illness: a multicentre, retrospective cohort study
Attokaran, Antony George, White, Kyle C., Doola, Ra'eesa, McIlroy, Philippa, Senthuran, Siva, Luke, Stephen, Garrett, Peter, Tabah, Alexis, Shekar, Kiran, Edwards, Felicity, White, Hayden, McCullough, James P.A., Hurford, Rod, Clement, Pierre, Laupland, Kevin B. and Ramanan, Mahesh (2024). Epidemiology of hypophosphatemia in critical illness: a multicentre, retrospective cohort study. Anaesthesia Critical Care and Pain Medicine, 43 (5) 101410, 1-9. doi: 10.1016/j.accpm.2024.101410
2024
Book Chapter
Respiratory support in COVID-19-related respiratory failure: Lessons learnt
Ling, Ryan Ruiyang, Ramanathan, Kollengode, Subramaniam, Ashwin and Shekar, Kiran (2024). Respiratory support in COVID-19-related respiratory failure: Lessons learnt. The COVID-19 Aftermath Volume I: Ongoing Challenges. (pp. 97-109) edited by Nima Rezaei. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-61939-7_5
2024
Book Chapter
Frailty in critically ill patients with COVID-19: The lessons learned
Subramaniam, Ashwin, Ling, Ryan Ruiyang and Shekar, Kiran (2024). Frailty in critically ill patients with COVID-19: The lessons learned. The COVID-19 Aftermath Volume I: Ongoing Challenges. (pp. 79-96) edited by Nima Rezaei. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-61939-7_4
2024
Journal Article
Point-of-care creatinine vs. central laboratory creatinine in the critically ill
White, Kyle C., McCullough, James, Shekar, Kiran, Senthuran, Siva, Laupland, Kevin B., Dimeski, Goce, Serpa-Neto, Ary and Bellomo, Rinaldo (2024). Point-of-care creatinine vs. central laboratory creatinine in the critically ill. Critical Care and Resuscitation, 26 (3), 198-203. doi: 10.1016/j.ccrj.2024.07.002
2024
Journal Article
Recommendations for the College of Intensive Care Medicine (CICM) trainee research project: A modified Delphi study
Ho, Ariel, Denny, Kerina J., Laupland, Kevin B., Ramanan, Mahesh, Tabah, Alexis, McCullough, James, Schults, Jessica A., Raman, Sainath, Apte, Yogesh, Attokaran, Antony, Baker, Stuart, Bartholdy, Roland, Bhadange, Neeraj, Brailsford, Jane, Cook, Katrina, David, Alexandre, Dhanani, Jayesh, Edwards, Felicity, Elkady, Hatem, Evans, Tess, Hutchinson, Jane, Lannon, Sean, Marshall, Andrea, McIlroy, Philippa, Milford, Elissa, Morrison, Lynette, Murray, Lauren, Serratore, Alyssa, Shah, Vikram ... Queensland Critical Care Research Network (2024). Recommendations for the College of Intensive Care Medicine (CICM) trainee research project: A modified Delphi study. Critical Care and Resuscitation, 26 (3), 169-175. doi: 10.1016/j.ccrj.2024.05.002
2024
Conference Publication
Mechanical left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a propensity score-matched analysis of the ELSO registry
Ling, Ryan, Chen, Ying, Shekar, Kiran, Brodie, Daniel, MacLaren, Graeme and Ramanathan, Kollengode (2024). Mechanical left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a propensity score-matched analysis of the ELSO registry. 35th Annual ELSO Conference, Detroit, MI United States, 28 September-1 October 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mat.0001069772.13398.04
2024
Conference Publication
Temporal trends in venovenous ECMO utilisation before and during the COVID-19 pandemic: an ELSO registry analysis
Ling, Ryan, Ramanathan, Kollengode, Chen, Ying, Barbaro, Ryan, Shekar, Kiran, Brodie, Daniel and MacLaren, Graeme (2024). Temporal trends in venovenous ECMO utilisation before and during the COVID-19 pandemic: an ELSO registry analysis. 35th Annual ELSO Conference, Detroit, MI United States, 28 September-1 October 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mat.0001070016.24292.ca
2024
Journal Article
Associations between late lactate clearance and clinical outcomes in adults with hyperlactataemia in the setting of diabetic ketoacidosis
Kumar, Aashish, Anstey, Christopher, Doola, Ra’eesa, Mcllroy, Philippa, Whebell, Stephen, Shekar, Kiran, Attokaran, Antony, Marella, Prashanti, White, Kyle, Luke, Stephen, Tabah, Alexis, Laupland, Kevin, Ramanan, Mahesh and Queensland Critical Care Research Network (QCCRN) (2024). Associations between late lactate clearance and clinical outcomes in adults with hyperlactataemia in the setting of diabetic ketoacidosis. Journal of Clinical Medicine, 13 (16) 4933, 1-12. doi: 10.3390/jcm13164933
2024
Journal Article
Immunomodulators in patients receiving extracorporeal membrane oxygenation for COVID-19: a propensity-score adjusted analysis of the ELSO registry
Ling, Ryan Ruiyang, Ramanathan, Kollengode, Shen, Liang, Barbaro, Ryan P., Shekar, Kiran, Brodie, Daniel and MacLaren, Graeme (2024). Immunomodulators in patients receiving extracorporeal membrane oxygenation for COVID-19: a propensity-score adjusted analysis of the ELSO registry. Annals of Intensive Care, 14 (1) 128, 1-10. doi: 10.1186/s13613-024-01368-1
2024
Journal Article
Neurologic complications in patients receiving aortic versus subclavian versus femoral arterial cannulation for post-cardiotomy extracorporeal life support: results of the PELS observational multicenter study
Chiarini, Giovanni, Mariani, Silvia, Schaefer, Anne-Kristin, van Bussel, Bas C T, Di Mauro, Michele, Wiedemann, Dominik, Saeed, Diyar, Pozzi, Matteo, Botta, Luca, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Bunge, Jeroen J H, Buscher, Hergen, Salazar, Leonardo, Meyns, Bart, Herr, Daniel, Matteucci, Sacha, Sponga, Sandro, Ramanathan, Kollengode, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo, Wang, I-Wen ... Lorusso, Roberto (2024). Neurologic complications in patients receiving aortic versus subclavian versus femoral arterial cannulation for post-cardiotomy extracorporeal life support: results of the PELS observational multicenter study. Critical Care, 28 (1) 265, 1-14. doi: 10.1186/s13054-024-05047-2
2024
Journal Article
Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi method: a PRORVnet study. Expert position statements
Zochios, Vasileios, Nasa, Prashant, Yusuff, Hakeem, Schultz, Marcus, Antonini, Marta, Duggal, Abhijit, Dugar, Siddharth, Ramanathan, Kollengode, Shekar, Kiran and Schmidt, Matthieu (2024). Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi method: a PRORVnet study. Expert position statements. Intensive Care Medicine, 50 (9), 1411-1425. doi: 10.1007/s00134-024-07551-z
2024
Journal Article
Characteristics and outcomes of prolonged venoarterial extracorporeal membrane oxygenation after cardiac surgery: the Post-Cardiotomy Extracorporeal Life Support (PELS-1) Cohort Study
Bunge, Jeroen J. H., Mariani, Silvia, Meuwese, Christiaan, van Bussel, Bas C. T., Di Mauro, Michele, Wiedeman, Dominik, Saeed, Diyar, Pozzi, Matteo, Loforte, Antonio, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Buscher, Hergen, Salazar, Leonardo, Meyns, Bart, Herr, Daniel, Matteucci, Sacha, Sponga, Sandro, MacLaren, Graeme, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo, Wang, I-wen, Jung, Jae-Seung ... on behalf of the Post-Cardiotomy Extracorporeal Life Support (PELS-1) Investigators (2024). Characteristics and outcomes of prolonged venoarterial extracorporeal membrane oxygenation after cardiac surgery: the Post-Cardiotomy Extracorporeal Life Support (PELS-1) Cohort Study. Critical Care Medicine, 52 (10), e490-e502. doi: 10.1097/ccm.0000000000006349
2024
Journal Article
COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study
Dhanani, Jayesh A., Shekar, Kiran, Parmar, Dinesh, Lipman, Jeffrey, Bristow, Debra, Wallis, Steven C., Won, Hayoung, Sumi, Chandra D., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2024). COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study. ASAIO Journal, 70 (6), 546-552. doi: 10.1097/MAT.0000000000002120
2024
Conference Publication
Outcomes of Paracorporeal Ventricular Assist Device Implantation: A Single Centre Experience
Shahwar, D., Mohan, R., Thomson, B. and Shekar, K. (2024). Outcomes of Paracorporeal Ventricular Assist Device Implantation: A Single Centre Experience. ANZSCTS Annual Scientific Meeting, Wellington, New Zealand, 9–11 November 2023. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.04.008
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kiran Shekar is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Single Hand Used inTubaTing Laryngoscope Evaluation (SHUTTLE) Project
Associate Advisor
Other advisors: Professor Jeffrey Lipman
Completed supervision
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2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Associate Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Professor Jason Roberts
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2019
Doctor Philosophy
Bioanalytical method development and validation to investigate cytochrome P450 mediated drug metabolism in patients receiving extracorporeal life support.
Associate Advisor
Other advisors: Emeritus Professor Maree Smith
Media
Enquiries
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