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Professor Kiran Shekar
Professor

Kiran Shekar

Email: 

Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 300 peer-reviewed articles, 60 conference abstracts, 14 book chapters and has delivered over 100 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

308 works between 2008 and 2025

41 - 60 of 308 works

2024

Journal Article

Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study

Ling, Ryan Ruiyang, Ponnapa Reddy, Mallikarjuna, Subramaniam, Ashwin, Moran, Benjamin, Ramanathan, Kollengode, Ramanan, Mahesh, Burrell, Aidan, Pilcher, David and Shekar, Kiran (2024). Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study. Intensive Care Medicine, 50 (11), 1861-1872. doi: 10.1007/s00134-024-07609-y

Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study

2024

Journal Article

Post-cardiotomy extracorporeal life support: a cohort of cannulation in the general ward

Bari, Gabor, Mariani, Silvia, van Bussel, Bas C. T., Ravaux, Justine, Di Mauro, Michele, Schaefer, Anne, Khalil, Jawad, Pozzi, Matteo, Botta, Luca, Pacini, Davide, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Bunge, Jeroen J. H., Buscher, Hergen, Salazar, Leonardo, Meyns, Bart, Mazeffi, Michael, Matteucci, Sacha, Sponga, Sandro, MacLaren, Graeme, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo ... Lorusso, Roberto (2024). Post-cardiotomy extracorporeal life support: a cohort of cannulation in the general ward. Artificial Organs, 48 (11), 1355-1365. doi: 10.1111/aor.14818

Post-cardiotomy extracorporeal life support: a cohort of cannulation in the general ward

2024

Journal Article

Hypothermia and Influence of Rewarming Rates on Survival Among Patients Admitted to Intensive Care with Bloodstream Infection: A Multicenter Cohort Study

White, Kyle C., Quick, Lachlan, Ramanan, Mahesh, Tabah, Alexis, Shekar, Kiran, Senthuran, Siva, Edwards, Felicity, Attokaran, Antony G., Kumar, Aashish, Meyer, Jason, McCullough, James, Blank, Sebastiaan, Smart, Christopher, Garrett, Peter, Laupland, Kevin B. and on behalf of the Queensland Critical Care Research Network (QCCRN) (2024). Hypothermia and Influence of Rewarming Rates on Survival Among Patients Admitted to Intensive Care with Bloodstream Infection: A Multicenter Cohort Study. Therapeutic Hypothermia and Temperature Management, 15 (3), 1-6. doi: 10.1089/ther.2024.0047

Hypothermia and Influence of Rewarming Rates on Survival Among Patients Admitted to Intensive Care with Bloodstream Infection: A Multicenter Cohort Study

2024

Journal Article

Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation (vol 50, pg 1470, 2024)

Burrell, Aidan, Bailey, Michael J., Bellomo, Rinaldo, Buscher, Hergen, Eastwood, Glenn, Forrest, Paul, Fraser, John F., Fulcher, Bentley, Gattas, David, Higgins, Alisa M., Hodgson, Carol L., Litton, Edward, Martin, Emma-Leah, Nair, Priya, Ng, Sze J., Orford, Neil, Ottosen, Kelly, Paul, Eldho, Pellegrino, Vincent, Reid, Liadain, Shekar, Kiran, Totaro, Richard J., Trapani, Tony, Udy, Andrew, Ziegenfuss, Marc, Pilcher, David and on behalf of The BLENDER Trial Investigators, EXCEL Registry, ECMONet and the Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group and Centre for Outcomes and Resource Evaluation (2024). Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation (vol 50, pg 1470, 2024). Intensive Care Medicine, 50 (12), 2241-2242. doi: 10.1007/s00134-024-07677-0

Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation (vol 50, pg 1470, 2024)

2024

Journal Article

ECMO: more than just a bridge over troubled waters?

Ling, Ryan Ruiyang, Ramanathan, Kollengode and Shekar, Kiran (2024). ECMO: more than just a bridge over troubled waters?. The Lancet Respiratory Medicine, 12 (10), 756-758. doi: 10.1016/s2213-2600(24)00261-3

ECMO: more than just a bridge over troubled waters?

2024

Journal Article

Definitions of adverse events associated with extracorporeal membrane oxygenation in children: results of an international Delphi process from the ECMO-CENTRAL ARC

Alexander, Peta M. A., Di Nardo, Matteo, Combes, Alain, Vogel, Adam M, Antonini, Marta Velia, Barrett, Nicholas, Benedetti, Giulia M, Bettencourt, Amanda, Brodie, Daniel, Gómez-Gutiérrez, René, Gorga, Stephen M., Hodgson, Carol, Kapoor, Poonam Malhotra, Le, Jennifer, MacLaren, Graeme, O'Neil, Erika R., Ostermann, Marlies, Paden, Matthew L., Patel, Neil, Rojas-Peña, Alvaro, Said, Ahmed S., Sperotto, Francesca, Willems, Ariane, Vercaemst, Leen, Yoganathan, Ajit P., Lorts, Angela, del Nido, Pedro J., Barbaro, Ryan P., Abecasis, Francisco ... Society of Thoracic Surgeons (STS), Society of Critical Care Medicine (SCCM) (2024). Definitions of adverse events associated with extracorporeal membrane oxygenation in children: results of an international Delphi process from the ECMO-CENTRAL ARC. The Lancet Child and Adolescent Health, 8 (10), 773-780. doi: 10.1016/S2352-4642(24)00132-9

Definitions of adverse events associated with extracorporeal membrane oxygenation in children: results of an international Delphi process from the ECMO-CENTRAL ARC

2024

Journal Article

Epidemiology of hypophosphatemia in critical illness: a multicentre, retrospective cohort study

Attokaran, Antony George, White, Kyle C., Doola, Ra'eesa, McIlroy, Philippa, Senthuran, Siva, Luke, Stephen, Garrett, Peter, Tabah, Alexis, Shekar, Kiran, Edwards, Felicity, White, Hayden, McCullough, James P.A., Hurford, Rod, Clement, Pierre, Laupland, Kevin B. and Ramanan, Mahesh (2024). Epidemiology of hypophosphatemia in critical illness: a multicentre, retrospective cohort study. Anaesthesia Critical Care and Pain Medicine, 43 (5) 101410, 1-9. doi: 10.1016/j.accpm.2024.101410

Epidemiology of hypophosphatemia in critical illness: a multicentre, retrospective cohort study

2024

Book Chapter

Respiratory support in COVID-19-related respiratory failure: Lessons learnt

Ling, Ryan Ruiyang, Ramanathan, Kollengode, Subramaniam, Ashwin and Shekar, Kiran (2024). Respiratory support in COVID-19-related respiratory failure: Lessons learnt. The COVID-19 Aftermath Volume I: Ongoing Challenges. (pp. 97-109) edited by Nima Rezaei. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-61939-7_5

Respiratory support in COVID-19-related respiratory failure: Lessons learnt

2024

Book Chapter

Frailty in critically ill patients with COVID-19: The lessons learned

Subramaniam, Ashwin, Ling, Ryan Ruiyang and Shekar, Kiran (2024). Frailty in critically ill patients with COVID-19: The lessons learned. The COVID-19 Aftermath Volume I: Ongoing Challenges. (pp. 79-96) edited by Nima Rezaei. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-61939-7_4

Frailty in critically ill patients with COVID-19: The lessons learned

2024

Journal Article

Point-of-care creatinine vs. central laboratory creatinine in the critically ill

White, Kyle C., McCullough, James, Shekar, Kiran, Senthuran, Siva, Laupland, Kevin B., Dimeski, Goce, Serpa-Neto, Ary and Bellomo, Rinaldo (2024). Point-of-care creatinine vs. central laboratory creatinine in the critically ill. Critical Care and Resuscitation, 26 (3), 198-203. doi: 10.1016/j.ccrj.2024.07.002

Point-of-care creatinine vs. central laboratory creatinine in the critically ill

2024

Journal Article

Recommendations for the College of Intensive Care Medicine (CICM) trainee research project: A modified Delphi study

Ho, Ariel, Denny, Kerina J., Laupland, Kevin B., Ramanan, Mahesh, Tabah, Alexis, McCullough, James, Schults, Jessica A., Raman, Sainath, Apte, Yogesh, Attokaran, Antony, Baker, Stuart, Bartholdy, Roland, Bhadange, Neeraj, Brailsford, Jane, Cook, Katrina, David, Alexandre, Dhanani, Jayesh, Edwards, Felicity, Elkady, Hatem, Evans, Tess, Hutchinson, Jane, Lannon, Sean, Marshall, Andrea, McIlroy, Philippa, Milford, Elissa, Morrison, Lynette, Murray, Lauren, Serratore, Alyssa, Shah, Vikram ... Queensland Critical Care Research Network (2024). Recommendations for the College of Intensive Care Medicine (CICM) trainee research project: A modified Delphi study. Critical Care and Resuscitation, 26 (3), 169-175. doi: 10.1016/j.ccrj.2024.05.002

Recommendations for the College of Intensive Care Medicine (CICM) trainee research project: A modified Delphi study

2024

Conference Publication

Mechanical left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a propensity score-matched analysis of the ELSO registry

Ling, Ryan, Chen, Ying, Shekar, Kiran, Brodie, Daniel, MacLaren, Graeme and Ramanathan, Kollengode (2024). Mechanical left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a propensity score-matched analysis of the ELSO registry. 35th Annual ELSO Conference, Detroit, MI United States, 28 September-1 October 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mat.0001069772.13398.04

Mechanical left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a propensity score-matched analysis of the ELSO registry

2024

Conference Publication

Temporal trends in venovenous ECMO utilisation before and during the COVID-19 pandemic: an ELSO registry analysis

Ling, Ryan, Ramanathan, Kollengode, Chen, Ying, Barbaro, Ryan, Shekar, Kiran, Brodie, Daniel and MacLaren, Graeme (2024). Temporal trends in venovenous ECMO utilisation before and during the COVID-19 pandemic: an ELSO registry analysis. 35th Annual ELSO Conference, Detroit, MI United States, 28 September-1 October 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mat.0001070016.24292.ca

Temporal trends in venovenous ECMO utilisation before and during the COVID-19 pandemic: an ELSO registry analysis

2024

Journal Article

Associations between late lactate clearance and clinical outcomes in adults with hyperlactataemia in the setting of diabetic ketoacidosis

Kumar, Aashish, Anstey, Christopher, Doola, Ra’eesa, Mcllroy, Philippa, Whebell, Stephen, Shekar, Kiran, Attokaran, Antony, Marella, Prashanti, White, Kyle, Luke, Stephen, Tabah, Alexis, Laupland, Kevin, Ramanan, Mahesh and Queensland Critical Care Research Network (QCCRN) (2024). Associations between late lactate clearance and clinical outcomes in adults with hyperlactataemia in the setting of diabetic ketoacidosis. Journal of Clinical Medicine, 13 (16) 4933, 1-12. doi: 10.3390/jcm13164933

Associations between late lactate clearance and clinical outcomes in adults with hyperlactataemia in the setting of diabetic ketoacidosis

2024

Journal Article

Immunomodulators in patients receiving extracorporeal membrane oxygenation for COVID-19: a propensity-score adjusted analysis of the ELSO registry

Ling, Ryan Ruiyang, Ramanathan, Kollengode, Shen, Liang, Barbaro, Ryan P., Shekar, Kiran, Brodie, Daniel and MacLaren, Graeme (2024). Immunomodulators in patients receiving extracorporeal membrane oxygenation for COVID-19: a propensity-score adjusted analysis of the ELSO registry. Annals of Intensive Care, 14 (1) 128, 1-10. doi: 10.1186/s13613-024-01368-1

Immunomodulators in patients receiving extracorporeal membrane oxygenation for COVID-19: a propensity-score adjusted analysis of the ELSO registry

2024

Journal Article

Neurologic complications in patients receiving aortic versus subclavian versus femoral arterial cannulation for post-cardiotomy extracorporeal life support: results of the PELS observational multicenter study

Chiarini, Giovanni, Mariani, Silvia, Schaefer, Anne-Kristin, van Bussel, Bas C T, Di Mauro, Michele, Wiedemann, Dominik, Saeed, Diyar, Pozzi, Matteo, Botta, Luca, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Bunge, Jeroen J H, Buscher, Hergen, Salazar, Leonardo, Meyns, Bart, Herr, Daniel, Matteucci, Sacha, Sponga, Sandro, Ramanathan, Kollengode, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo, Wang, I-Wen ... Lorusso, Roberto (2024). Neurologic complications in patients receiving aortic versus subclavian versus femoral arterial cannulation for post-cardiotomy extracorporeal life support: results of the PELS observational multicenter study. Critical Care, 28 (1) 265, 1-14. doi: 10.1186/s13054-024-05047-2

Neurologic complications in patients receiving aortic versus subclavian versus femoral arterial cannulation for post-cardiotomy extracorporeal life support: results of the PELS observational multicenter study

2024

Journal Article

Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi method: a PRORVnet study. Expert position statements

Zochios, Vasileios, Nasa, Prashant, Yusuff, Hakeem, Schultz, Marcus, Antonini, Marta, Duggal, Abhijit, Dugar, Siddharth, Ramanathan, Kollengode, Shekar, Kiran and Schmidt, Matthieu (2024). Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi method: a PRORVnet study. Expert position statements. Intensive Care Medicine, 50 (9), 1411-1425. doi: 10.1007/s00134-024-07551-z

Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi method: a PRORVnet study. Expert position statements

2024

Journal Article

Characteristics and outcomes of prolonged venoarterial extracorporeal membrane oxygenation after cardiac surgery: the Post-Cardiotomy Extracorporeal Life Support (PELS-1) Cohort Study

Bunge, Jeroen J. H., Mariani, Silvia, Meuwese, Christiaan, van Bussel, Bas C. T., Di Mauro, Michele, Wiedeman, Dominik, Saeed, Diyar, Pozzi, Matteo, Loforte, Antonio, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Buscher, Hergen, Salazar, Leonardo, Meyns, Bart, Herr, Daniel, Matteucci, Sacha, Sponga, Sandro, MacLaren, Graeme, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo, Wang, I-wen, Jung, Jae-Seung ... on behalf of the Post-Cardiotomy Extracorporeal Life Support (PELS-1) Investigators (2024). Characteristics and outcomes of prolonged venoarterial extracorporeal membrane oxygenation after cardiac surgery: the Post-Cardiotomy Extracorporeal Life Support (PELS-1) Cohort Study. Critical Care Medicine, 52 (10), e490-e502. doi: 10.1097/ccm.0000000000006349

Characteristics and outcomes of prolonged venoarterial extracorporeal membrane oxygenation after cardiac surgery: the Post-Cardiotomy Extracorporeal Life Support (PELS-1) Cohort Study

2024

Journal Article

COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study

Dhanani, Jayesh A., Shekar, Kiran, Parmar, Dinesh, Lipman, Jeffrey, Bristow, Debra, Wallis, Steven C., Won, Hayoung, Sumi, Chandra D., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2024). COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study. ASAIO Journal, 70 (6), 546-552. doi: 10.1097/MAT.0000000000002120

COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study

2024

Conference Publication

Outcomes of Paracorporeal Ventricular Assist Device Implantation: A Single Centre Experience

Shahwar, D., Mohan, R., Thomson, B. and Shekar, K. (2024). Outcomes of Paracorporeal Ventricular Assist Device Implantation: A Single Centre Experience. ANZSCTS Annual Scientific Meeting, Wellington, New Zealand, 9–11 November 2023. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.04.008

Outcomes of Paracorporeal Ventricular Assist Device Implantation: A Single Centre Experience

Funding

Current funding

  • 2025 - 2030
    Integrating sequencing technologies for bloodstream infection and sepsis diagnostics in critically-ill patients
    NHMRC MRFF Genomics Health Futures Mission
    Open grant
  • 2025 - 2030
    ROAD RCT: Resistance Optimised Antibiotic Dosing in critically ill patients - a Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2023 - 2028
    A national critical care research platform to ensure high quality sepsis care in Australian ICUs (MRFF EMCR led by Monash University)
    Monash University
    Open grant
  • 2022 - 2026
    PRecision Ecmo in CardIogenic Shock Evaluation: PRECISE Study (MRFF grant administered by Monash University)
    Monash University
    Open grant

Past funding

  • 2019
    Establishing UQ Centre for Clinical Research as the centre for Aerosol therapy in critical care by optimising particle size of aerosols for effective drug delivery.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Single Hand Used inTubaTing Laryngoscope Evaluation (SHUTTLE) Project

    Associate Advisor

    Other advisors: Professor Jeffrey Lipman

Completed supervision

Media

Enquiries

Contact Professor Kiran Shekar directly for media enquiries about their areas of expertise.

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