
Overview
Background
Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 300 peer-reviewed articles, 60 conference abstracts, 14 book chapters and has delivered over 100 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.
Availability
- Professor Kiran Shekar is:
- Available for supervision
- Media expert
Research interests
-
Extracorporeal membrane oxygenation
-
Respiratory failure and minimising the burden of invasive mechanical ventilation
-
PK/PD on Extracorporeal membrane oxygenation support
-
Cardiogenic Shock and Mechanical Circulatory Support
-
Microcirculation on temporary Mechanical Circulatory Support
-
Building a budget intensive care unit to improve intensive care access in resource poor countries
-
Standardising ECMO education to bridge the variability in global ECMO outcomes
Works
Search Professor Kiran Shekar’s works on UQ eSpace
2025
Journal Article
The impact of a tailored nutrition intervention delivered for the duration of hospitalisation on daily energy delivery for patients with critical illness (INTENT): a phase II randomised controlled trial
Ridley, Emma J., Bailey, Michael, Chapman, Marianne J., Chapple, Lee-anne S., Deane, Adam M., Gojanovic, Marlene, Higgins, Alisa M., Hodgson, Carol L., King, Victoria L., Marshall, Andrea P., Miller, Eliza G., McGuinness, Shay P., Parke, Rachael L., Paul, Eldho, Udy, Andrew A., Trickey, Jemma, Salerno, Tania, Maiden, Matthew, Kakho, Nima, Horton, Michelle, Williams, Patricia, Thatcher, Amber, Peake, Sandra, Kurenda, Cathy, Hatzi, Martine, Direen, Tennealle, Whitmore, Emma, Vasudevan, Marion, Shekar, Kiran (Australian, New Zealand Intensive Care Society Clinical Trials Group member) ... Ridley, Emma J. (2025). The impact of a tailored nutrition intervention delivered for the duration of hospitalisation on daily energy delivery for patients with critical illness (INTENT): a phase II randomised controlled trial. Critical Care, 29 (1) 8. doi: 10.1186/s13054-024-05189-3
2025
Journal Article
Left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a target trial emulation of the ELSO registry
Ling, Ryan Ruiyang, Chen, Ying, Low, Christopher Jer Wei, Agerstrand, Cara, Jung, Jae-Seung, Lim, Shir-Lynn, Lorusso, Roberto, Müeller, Thomas, Okada, Yohei, Tonna, Joseph E., Shekar, Kiran, Brodie, Daniel, MacLaren, Graeme and Ramanathan, Kollengode (2025). Left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a target trial emulation of the ELSO registry. Critical Care, 29 (1) 186, 186-1. doi: 10.1186/s13054-025-05345-3
2025
Journal Article
Missing the target in target trial emulation: the authors reply
Ling, Ryan Ruiyang, Chen, Ying, Shekar, Kiran, Brodie, Daniel, MacLaren, Graeme and Ramanathan, Kollengode (2025). Missing the target in target trial emulation: the authors reply. Critical Care, 29 (1) 311, 1. doi: 10.1186/s13054-025-05567-5
2025
Journal Article
Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data
Thao, Le Thi Phuong, Buscher, Hergen, Nguyen, Tri-Long, Martucci, Gennaro, Gratz, Johannes, Trummer, Georg, Schmidt, Matthieu, Gautier, Melchior, Serra, Alexis, Takeda, Koji, Pooth, Jan-Steffen, Rahn, Kevin, Geismann, Florian, Lubnow, Matthias, Retter, Andrew, Nair, Priya, Vlok, Ruan, Siriwardena, Maithri, Winearls, James, Walsham, James, Gattas, David, Aneman, Anders, Fulcher, Bentley, Newman, Sally, Reynolds, Claire, Arcadipane, Anthonio, Shekar, Kiran, Hodgson, Carol, Pellegrino, Vincent ... International ECMO Network (ECMONet) (2025). Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data. Critical Care, 29 (1) 360, 1-10. doi: 10.1186/s13054-025-05606-1
2025
Journal Article
Extracorporeal life support for adult patients with ARDS
Combes, Alain, Supady, Alexander, Abrams, Darryl, Agerstrand, Cara, Badulak, Jenelle, Camporota, Luigi, Fan, Eddy, Ferguson, Niall D., Fraser, John F., Hodgson, Carol, Jaber, Samir, MacLaren, Graeme, Patel, Brijesh V., Peek, Giles J., Schmidt, Matthieu, Shekar, Kiran, Slutsky, Arthur S. and Brodie, Daniel (2025). Extracorporeal life support for adult patients with ARDS. Intensive Care Medicine, 51 (9), 1-13. doi: 10.1007/s00134-025-08070-1
2025
Journal Article
Acute kidney injury detection with additional point-of-care creatinine vs central laboratory serum creatinine measurement in critically ill patients
White, Kyle C., Meyer, Jason, Laupland, Kevin B., Senthuran, Siva, Shekar, Kiran, McCullough, James and Bellomo, Rinaldo (2025). Acute kidney injury detection with additional point-of-care creatinine vs central laboratory serum creatinine measurement in critically ill patients. Journal of Critical Care, 88 155050, 155050-88. doi: 10.1016/j.jcrc.2025.155050
2025
Conference Publication
Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study
Ashby, A., Anstey, C., Attokaran, A., Siriwarden, M., Mullany, D., Kumar, A., Pryke, C., Laupland, K., Tabah, A., Shekar, K., Blank, S., Whebell, S., Luke, S., Raman, S., Garrett, P., McCullough, J., White, K. and Ramanan, M. (2025). Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study. 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Sydney, NSW Australia, 14-17 August 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.06.237
2025
Journal Article
Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology network
Morales Castro, Diana, Al-Fares, Abdulrahman Abdullah, Paternoster, Gianluca, Lyster, Haifa, Hohlfelder, Benjamin, Arias Ortiz, Julian, Abdul-Aziz, Mohd Hafiz, Herr, Daniel, Alraish, Rawan, Ferre Contreras, Andrés, Palavecino, Marcela, Milella, Luigi, Watt, Kevin, Alkazemi, Afrah, Carini, Federico Carlos, Roberts, Jason A., Riera Del Brio, Jordi, Parra, Alba Pau, Kakar, Vivek, Dureau, Pauline, Duceppe, Marc-Alexandre, Alm, Mark, Cha, Stephanie, Shekar, Kiran, Dzierba, Amy L. and Extracorporeal Membrane Oxygenation Pharmacology Network (ECMOPharm Net) (2025). Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology network. Critical Care Medicine. doi: 10.1097/CCM.0000000000006806
2025
Journal Article
Metabolic alkalosis acquired in intensive care: a retrospective cohort study
Goh, Gordon, Blank, Sebastiaan, Doola, Ra’eesa, Alder, Nelson, Ahuja, Abhilasha, Laupland, Kevin B., Tabah, Alexis, Shekar, Kiran, Kumar, Aashish, White, Kyle, Attokaran, Antony, Luke, Stephen, Whebell, Stephen, Garrett, Peter, Nesbitt, Alexander, McCullough, James, McIlroy, Philippa and Ramanan, Mahesh (2025). Metabolic alkalosis acquired in intensive care: a retrospective cohort study. Anaesthesia Critical Care & Pain Medicine, 44 (6) 101591, 101591-6. doi: 10.1016/j.accpm.2025.101591
2025
Journal Article
Persistent critical illness and long-term survival in cardiac surgery: A multicentre cohort study
Subramaniam, Ashwin, Ling, Ryan Ruiyang, Bonavia, William, Ramanathan, Kollengode, Ramanan, Mahesh, Shekar, Kiran and Pilcher, David (2025). Persistent critical illness and long-term survival in cardiac surgery: A multicentre cohort study. Anaesthesia Critical Care & Pain Medicine, 44 (6) 101593, 101593. doi: 10.1016/j.accpm.2025.101593
2025
Journal Article
Storage duration of packed red blood cells transfused during veno-venous extracorporeal membrane oxygenation is associated with elevated pulmonary artery pressure and lung injury in a sheep model
Temple, Fergal T., Simonova, Gabriela, Passmore, Margaret R., Foley, Samuel R., Diab, Sara D., Dunster, Kimble R., McDonald, Charles I., Shekar, Kiran, Fung, Yoke-Lin, Tung, John-Paul and Fraser, John F. (2025). Storage duration of packed red blood cells transfused during veno-venous extracorporeal membrane oxygenation is associated with elevated pulmonary artery pressure and lung injury in a sheep model. Critical Care, 29 (1) 240, 1. doi: 10.1186/s13054-025-05438-z
2025
Journal Article
Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation
Blank, Sebastiaan Paul, Blank, Ruth Miriam, Laupland, Kevin B., Tabah, Alexis, Gill, Denzil, Kumar, Aashish, White, Kyle, Attokaran, Antony, Luke, Stephen, Whebell, Stephen, Garrett, Peter, McCullough, James, McIlroy, Philippa, Ramanan, Mahesh, Keogh, Sam, Tyack, Zephanie, Gatton, Michelle, Nash, Ben, Blank, Sebastiaan, Dash, Sananta, Senthuran, Siva, Smart, Christopher, Taylor, Jennifer, Paasilahti, Anni, Reoch, Josephine, Poggenpoel, Jaco, Attokaran, Antony G., Anderson, Cameron, Lutshaba, Langa ... Denny, Kerina J. (2025). Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation. Intensive Care Medicine, 51 (6), 1078-1086. doi: 10.1007/s00134-025-07979-x
2025
Journal Article
Right ventricular injury definition and management in veno-venous extracorporeal membrane oxygenation
Dugar, Siddharth Pawan, Sato, Ryota, Charlton, Matthew, Hasegawa, Daisuke, Antonini, Marta Velia, Nasa, Prashant, Yusuff, Hakeem, Schultz, Marcus J., Harnegie, Mary Pat, Ramanathan, Kollengode, Shekar, Kiran, Schmidt, Matthieu, Zochios, Vasileios, Duggal, Abhijit and on behalf of Protecting the Right Ventricle Network (PRORVnet) (2025). Right ventricular injury definition and management in veno-venous extracorporeal membrane oxygenation. ASAIO Journal, 71 (6), 482-491. doi: 10.1097/mat.0000000000002369
2025
Journal Article
Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study
Zimsen, Tarren, Quick, Lachlan, White, Gentry, Costa-Pinto, Rahul, Whebell, Stephen, Meyer, Jason, McCullough, James, Shekar, Kiran, Laupland, Kevin B., Ramanan, Mahesh, Blank, Sebastiaan, Tabah, Alexis, Luke, Stephen, Garrett, Peter, Attokaran, Antony G., Kumar, Aashish and White, Kyle C. (2025). Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study. Critical Care and Resuscitation, 27 (2) 100112, 100112-2. doi: 10.1016/j.ccrj.2025.100112
2025
Journal Article
Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study
White, Kyle C., Bellomo, Rinaldo, Laupland, Kevin B., Gatton, Michelle L., Ostermann, Marlies, McIlroy, Philipa, Luke, Stephen, Garrett, Peter, Tabah, Alexis, Whebell, Stephen, Marella, Prashanti, McCullough, James, Shekar, Kiran, Attokaran, Antony G., Kumar, Aashish, Meyer, Jason, Sanderson, Barnaby, Serpa-Neto, Ary, Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David, White, Hayden ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2025). Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study. Journal of Critical Care, 87 155016, 1-9. doi: 10.1016/j.jcrc.2025.155016
2025
Journal Article
Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation
White, Kyle C., Costa-Pinto, Rahul, Blank, Sebastiaan, Whebell, Stephen, Quick, Lachlan, Luke, Stephen, Attokaran, Antony G., Garrett, Peter, Ramanan, Mahesh, Tabah, Alexis, Shekar, Kiran, Laupland, Kevin B., Kumar, Aashish, McCullough, James, Udy, Andrew, Eastwood, Glenn, Bellomo, Rinaldo, Chaba, Anis, the Queensland Critical Care Research Network (QCCRN), Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David ... Keogh, Sam (2025). Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation. Critical Care, 29 (1) 188, 1-10. doi: 10.1186/s13054-025-05401-y
2025
Journal Article
Frailty and Long-Term Survival in Patients With Critical Illness After Nonhome Discharge: A Retrospective Cohort Study
Mehta, Hardik, Ling, Ryan Ruiyang, Ramanan, Mahesh, Bartlett, Catherine, Grewal, Jatinder, Gupta, Kshityj, Reynolds, James, Kumar, Aashish, Marella, Prashanti, Pilcher, David, Shah, Nilesh, Shekar, Kiran and Subramaniam, Ashwin (2025). Frailty and Long-Term Survival in Patients With Critical Illness After Nonhome Discharge: A Retrospective Cohort Study. Critical Care Medicine, 53 (7), e1402-e1415. doi: 10.1097/ccm.0000000000006684
2025
Journal Article
Kidney replacement therapy during extracorporeal membrane oxygenation: pathophysiology, technical considerations, and outcomes
Lau, Michele Petrova Xin Ling, Ling, Ryan Ruiyang, Ong, Brandon Jin An, Cho, Hwa Jin, Jeong, In-seok, Sahoo, Tapas Kumar, Chua, Horng Ruey, Shekar, Kiran and Ramanathan, Kollengode (2025). Kidney replacement therapy during extracorporeal membrane oxygenation: pathophysiology, technical considerations, and outcomes. Renal Failure, 47 (1) 2486557, 2486557. doi: 10.1080/0886022x.2025.2486557
2025
Journal Article
Preferences for thromboprophylaxis in the intensive care unit: An international survey
Heijkoop, emese Robin Helene, Keus, Frederik, Moller, Morten Hylander, Perner, Anders, Morgan, Matthew, Abdelhadi, Adel, al Shirawi, Nehad Nabeel Mohamed, Al-Fares, Abdulrahman A., Alshamsi, Fayez, Ananthan, Prakkash Parangi, Andreasen, Anne Sofie, Anstey, Matthew H., Arabi, Yaseen M., Aslam, Tayyba Naz, Attokaran, Antony George, Bestle, Morten H., Bhadange, Neeraj, Blaser, Annika Reintam, Brochner, Anne Craveiro, Cronhjort, Maria, Dabrowski, Wojciech, Elhoufi, Ashraf, Ergan, Begum, Ferrer, Ricard, Freebairn, Ross, Fujii, Tomoko, Greco, Massimiliano, van Haren, Frank M. P., Hildebrandt, Thomas ... Eck, Ruben Julius (2025). Preferences for thromboprophylaxis in the intensive care unit: An international survey. Acta Anaesthesiologica Scandinavica, 69 (4) e70009, e70009. doi: 10.1111/aas.70009
2025
Conference Publication
Staged ECMO Reconfiguration as a Bridge to Recovery Following Pulmonary Endarterectomy for CTEPH With Large Thrombus Burden in a Septuagenarian
Raza, S., Sharma, V., Shekar, K. and Thomson, B. (2025). Staged ECMO Reconfiguration as a Bridge to Recovery Following Pulmonary Endarterectomy for CTEPH With Large Thrombus Burden in a Septuagenarian. ANZSCTS Annual Scientific Meeting, Noosa, QLD Australia, 7–9 November 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.02.087
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kiran Shekar is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Single Hand Used inTubaTing Laryngoscope Evaluation (SHUTTLE) Project
Associate Advisor
Other advisors: Professor Jeffrey Lipman
Completed supervision
-
2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Associate Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Professor Jason Roberts
-
2019
Doctor Philosophy
Bioanalytical method development and validation to investigate cytochrome P450 mediated drug metabolism in patients receiving extracorporeal life support.
Associate Advisor
Other advisors: Emeritus Professor Maree Smith
Media
Enquiries
Contact Professor Kiran Shekar directly for media enquiries about their areas of expertise.
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: