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Professor Kiran Shekar
Professor

Kiran Shekar

Email: 

Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 300 peer-reviewed articles, 60 conference abstracts, 14 book chapters and has delivered over 100 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

308 works between 2008 and 2025

1 - 20 of 308 works

2025

Journal Article

The impact of a tailored nutrition intervention delivered for the duration of hospitalisation on daily energy delivery for patients with critical illness (INTENT): a phase II randomised controlled trial

Ridley, Emma J., Bailey, Michael, Chapman, Marianne J., Chapple, Lee-anne S., Deane, Adam M., Gojanovic, Marlene, Higgins, Alisa M., Hodgson, Carol L., King, Victoria L., Marshall, Andrea P., Miller, Eliza G., McGuinness, Shay P., Parke, Rachael L., Paul, Eldho, Udy, Andrew A., Trickey, Jemma, Salerno, Tania, Maiden, Matthew, Kakho, Nima, Horton, Michelle, Williams, Patricia, Thatcher, Amber, Peake, Sandra, Kurenda, Cathy, Hatzi, Martine, Direen, Tennealle, Whitmore, Emma, Vasudevan, Marion, Shekar, Kiran (Australian, New Zealand Intensive Care Society Clinical Trials Group member) ... Ridley, Emma J. (2025). The impact of a tailored nutrition intervention delivered for the duration of hospitalisation on daily energy delivery for patients with critical illness (INTENT): a phase II randomised controlled trial. Critical Care, 29 (1) 8. doi: 10.1186/s13054-024-05189-3

The impact of a tailored nutrition intervention delivered for the duration of hospitalisation on daily energy delivery for patients with critical illness (INTENT): a phase II randomised controlled trial

2025

Journal Article

Left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a target trial emulation of the ELSO registry

Ling, Ryan Ruiyang, Chen, Ying, Low, Christopher Jer Wei, Agerstrand, Cara, Jung, Jae-Seung, Lim, Shir-Lynn, Lorusso, Roberto, Müeller, Thomas, Okada, Yohei, Tonna, Joseph E., Shekar, Kiran, Brodie, Daniel, MacLaren, Graeme and Ramanathan, Kollengode (2025). Left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a target trial emulation of the ELSO registry. Critical Care, 29 (1) 186, 186-1. doi: 10.1186/s13054-025-05345-3

Left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a target trial emulation of the ELSO registry

2025

Journal Article

Missing the target in target trial emulation: the authors reply

Ling, Ryan Ruiyang, Chen, Ying, Shekar, Kiran, Brodie, Daniel, MacLaren, Graeme and Ramanathan, Kollengode (2025). Missing the target in target trial emulation: the authors reply. Critical Care, 29 (1) 311, 1. doi: 10.1186/s13054-025-05567-5

Missing the target in target trial emulation: the authors reply

2025

Journal Article

Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data

Thao, Le Thi Phuong, Buscher, Hergen, Nguyen, Tri-Long, Martucci, Gennaro, Gratz, Johannes, Trummer, Georg, Schmidt, Matthieu, Gautier, Melchior, Serra, Alexis, Takeda, Koji, Pooth, Jan-Steffen, Rahn, Kevin, Geismann, Florian, Lubnow, Matthias, Retter, Andrew, Nair, Priya, Vlok, Ruan, Siriwardena, Maithri, Winearls, James, Walsham, James, Gattas, David, Aneman, Anders, Fulcher, Bentley, Newman, Sally, Reynolds, Claire, Arcadipane, Anthonio, Shekar, Kiran, Hodgson, Carol, Pellegrino, Vincent ... International ECMO Network (ECMONet) (2025). Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data. Critical Care, 29 (1) 360, 1-10. doi: 10.1186/s13054-025-05606-1

Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data

2025

Journal Article

Extracorporeal life support for adult patients with ARDS

Combes, Alain, Supady, Alexander, Abrams, Darryl, Agerstrand, Cara, Badulak, Jenelle, Camporota, Luigi, Fan, Eddy, Ferguson, Niall D., Fraser, John F., Hodgson, Carol, Jaber, Samir, MacLaren, Graeme, Patel, Brijesh V., Peek, Giles J., Schmidt, Matthieu, Shekar, Kiran, Slutsky, Arthur S. and Brodie, Daniel (2025). Extracorporeal life support for adult patients with ARDS. Intensive Care Medicine, 51 (9), 1-13. doi: 10.1007/s00134-025-08070-1

Extracorporeal life support for adult patients with ARDS

2025

Journal Article

Acute kidney injury detection with additional point-of-care creatinine vs central laboratory serum creatinine measurement in critically ill patients

White, Kyle C., Meyer, Jason, Laupland, Kevin B., Senthuran, Siva, Shekar, Kiran, McCullough, James and Bellomo, Rinaldo (2025). Acute kidney injury detection with additional point-of-care creatinine vs central laboratory serum creatinine measurement in critically ill patients. Journal of Critical Care, 88 155050, 155050-88. doi: 10.1016/j.jcrc.2025.155050

Acute kidney injury detection with additional point-of-care creatinine vs central laboratory serum creatinine measurement in critically ill patients

2025

Conference Publication

Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study

Ashby, A., Anstey, C., Attokaran, A., Siriwarden, M., Mullany, D., Kumar, A., Pryke, C., Laupland, K., Tabah, A., Shekar, K., Blank, S., Whebell, S., Luke, S., Raman, S., Garrett, P., McCullough, J., White, K. and Ramanan, M. (2025). Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study. 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Sydney, NSW Australia, 14-17 August 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.06.237

Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study

2025

Journal Article

Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology network

Morales Castro, Diana, Al-Fares, Abdulrahman Abdullah, Paternoster, Gianluca, Lyster, Haifa, Hohlfelder, Benjamin, Arias Ortiz, Julian, Abdul-Aziz, Mohd Hafiz, Herr, Daniel, Alraish, Rawan, Ferre Contreras, Andrés, Palavecino, Marcela, Milella, Luigi, Watt, Kevin, Alkazemi, Afrah, Carini, Federico Carlos, Roberts, Jason A., Riera Del Brio, Jordi, Parra, Alba Pau, Kakar, Vivek, Dureau, Pauline, Duceppe, Marc-Alexandre, Alm, Mark, Cha, Stephanie, Shekar, Kiran, Dzierba, Amy L. and Extracorporeal Membrane Oxygenation Pharmacology Network (ECMOPharm Net) (2025). Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology network. Critical Care Medicine. doi: 10.1097/CCM.0000000000006806

Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology network

2025

Journal Article

Metabolic alkalosis acquired in intensive care: a retrospective cohort study

Goh, Gordon, Blank, Sebastiaan, Doola, Ra’eesa, Alder, Nelson, Ahuja, Abhilasha, Laupland, Kevin B., Tabah, Alexis, Shekar, Kiran, Kumar, Aashish, White, Kyle, Attokaran, Antony, Luke, Stephen, Whebell, Stephen, Garrett, Peter, Nesbitt, Alexander, McCullough, James, McIlroy, Philippa and Ramanan, Mahesh (2025). Metabolic alkalosis acquired in intensive care: a retrospective cohort study. Anaesthesia Critical Care & Pain Medicine, 44 (6) 101591, 101591-6. doi: 10.1016/j.accpm.2025.101591

Metabolic alkalosis acquired in intensive care: a retrospective cohort study

2025

Journal Article

Persistent critical illness and long-term survival in cardiac surgery: A multicentre cohort study

Subramaniam, Ashwin, Ling, Ryan Ruiyang, Bonavia, William, Ramanathan, Kollengode, Ramanan, Mahesh, Shekar, Kiran and Pilcher, David (2025). Persistent critical illness and long-term survival in cardiac surgery: A multicentre cohort study. Anaesthesia Critical Care & Pain Medicine, 44 (6) 101593, 101593. doi: 10.1016/j.accpm.2025.101593

Persistent critical illness and long-term survival in cardiac surgery: A multicentre cohort study

2025

Journal Article

Storage duration of packed red blood cells transfused during veno-venous extracorporeal membrane oxygenation is associated with elevated pulmonary artery pressure and lung injury in a sheep model

Temple, Fergal T., Simonova, Gabriela, Passmore, Margaret R., Foley, Samuel R., Diab, Sara D., Dunster, Kimble R., McDonald, Charles I., Shekar, Kiran, Fung, Yoke-Lin, Tung, John-Paul and Fraser, John F. (2025). Storage duration of packed red blood cells transfused during veno-venous extracorporeal membrane oxygenation is associated with elevated pulmonary artery pressure and lung injury in a sheep model. Critical Care, 29 (1) 240, 1. doi: 10.1186/s13054-025-05438-z

Storage duration of packed red blood cells transfused during veno-venous extracorporeal membrane oxygenation is associated with elevated pulmonary artery pressure and lung injury in a sheep model

2025

Journal Article

Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation

Blank, Sebastiaan Paul, Blank, Ruth Miriam, Laupland, Kevin B., Tabah, Alexis, Gill, Denzil, Kumar, Aashish, White, Kyle, Attokaran, Antony, Luke, Stephen, Whebell, Stephen, Garrett, Peter, McCullough, James, McIlroy, Philippa, Ramanan, Mahesh, Keogh, Sam, Tyack, Zephanie, Gatton, Michelle, Nash, Ben, Blank, Sebastiaan, Dash, Sananta, Senthuran, Siva, Smart, Christopher, Taylor, Jennifer, Paasilahti, Anni, Reoch, Josephine, Poggenpoel, Jaco, Attokaran, Antony G., Anderson, Cameron, Lutshaba, Langa ... Denny, Kerina J. (2025). Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation. Intensive Care Medicine, 51 (6), 1078-1086. doi: 10.1007/s00134-025-07979-x

Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation

2025

Journal Article

Right ventricular injury definition and management in veno-venous extracorporeal membrane oxygenation

Dugar, Siddharth Pawan, Sato, Ryota, Charlton, Matthew, Hasegawa, Daisuke, Antonini, Marta Velia, Nasa, Prashant, Yusuff, Hakeem, Schultz, Marcus J., Harnegie, Mary Pat, Ramanathan, Kollengode, Shekar, Kiran, Schmidt, Matthieu, Zochios, Vasileios, Duggal, Abhijit and on behalf of Protecting the Right Ventricle Network (PRORVnet) (2025). Right ventricular injury definition and management in veno-venous extracorporeal membrane oxygenation. ASAIO Journal, 71 (6), 482-491. doi: 10.1097/mat.0000000000002369

Right ventricular injury definition and management in veno-venous extracorporeal membrane oxygenation

2025

Journal Article

Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study

Zimsen, Tarren, Quick, Lachlan, White, Gentry, Costa-Pinto, Rahul, Whebell, Stephen, Meyer, Jason, McCullough, James, Shekar, Kiran, Laupland, Kevin B., Ramanan, Mahesh, Blank, Sebastiaan, Tabah, Alexis, Luke, Stephen, Garrett, Peter, Attokaran, Antony G., Kumar, Aashish and White, Kyle C. (2025). Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study. Critical Care and Resuscitation, 27 (2) 100112, 100112-2. doi: 10.1016/j.ccrj.2025.100112

Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study

2025

Journal Article

Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study

White, Kyle C., Bellomo, Rinaldo, Laupland, Kevin B., Gatton, Michelle L., Ostermann, Marlies, McIlroy, Philipa, Luke, Stephen, Garrett, Peter, Tabah, Alexis, Whebell, Stephen, Marella, Prashanti, McCullough, James, Shekar, Kiran, Attokaran, Antony G., Kumar, Aashish, Meyer, Jason, Sanderson, Barnaby, Serpa-Neto, Ary, Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David, White, Hayden ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2025). Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study. Journal of Critical Care, 87 155016, 1-9. doi: 10.1016/j.jcrc.2025.155016

Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study

2025

Journal Article

Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation

White, Kyle C., Costa-Pinto, Rahul, Blank, Sebastiaan, Whebell, Stephen, Quick, Lachlan, Luke, Stephen, Attokaran, Antony G., Garrett, Peter, Ramanan, Mahesh, Tabah, Alexis, Shekar, Kiran, Laupland, Kevin B., Kumar, Aashish, McCullough, James, Udy, Andrew, Eastwood, Glenn, Bellomo, Rinaldo, Chaba, Anis, the Queensland Critical Care Research Network (QCCRN), Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David ... Keogh, Sam (2025). Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation. Critical Care, 29 (1) 188, 1-10. doi: 10.1186/s13054-025-05401-y

Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation

2025

Journal Article

Frailty and Long-Term Survival in Patients With Critical Illness After Nonhome Discharge: A Retrospective Cohort Study

Mehta, Hardik, Ling, Ryan Ruiyang, Ramanan, Mahesh, Bartlett, Catherine, Grewal, Jatinder, Gupta, Kshityj, Reynolds, James, Kumar, Aashish, Marella, Prashanti, Pilcher, David, Shah, Nilesh, Shekar, Kiran and Subramaniam, Ashwin (2025). Frailty and Long-Term Survival in Patients With Critical Illness After Nonhome Discharge: A Retrospective Cohort Study. Critical Care Medicine, 53 (7), e1402-e1415. doi: 10.1097/ccm.0000000000006684

Frailty and Long-Term Survival in Patients With Critical Illness After Nonhome Discharge: A Retrospective Cohort Study

2025

Journal Article

Kidney replacement therapy during extracorporeal membrane oxygenation: pathophysiology, technical considerations, and outcomes

Lau, Michele Petrova Xin Ling, Ling, Ryan Ruiyang, Ong, Brandon Jin An, Cho, Hwa Jin, Jeong, In-seok, Sahoo, Tapas Kumar, Chua, Horng Ruey, Shekar, Kiran and Ramanathan, Kollengode (2025). Kidney replacement therapy during extracorporeal membrane oxygenation: pathophysiology, technical considerations, and outcomes. Renal Failure, 47 (1) 2486557, 2486557. doi: 10.1080/0886022x.2025.2486557

Kidney replacement therapy during extracorporeal membrane oxygenation: pathophysiology, technical considerations, and outcomes

2025

Journal Article

Preferences for thromboprophylaxis in the intensive care unit: An international survey

Heijkoop, emese Robin Helene, Keus, Frederik, Moller, Morten Hylander, Perner, Anders, Morgan, Matthew, Abdelhadi, Adel, al Shirawi, Nehad Nabeel Mohamed, Al-Fares, Abdulrahman A., Alshamsi, Fayez, Ananthan, Prakkash Parangi, Andreasen, Anne Sofie, Anstey, Matthew H., Arabi, Yaseen M., Aslam, Tayyba Naz, Attokaran, Antony George, Bestle, Morten H., Bhadange, Neeraj, Blaser, Annika Reintam, Brochner, Anne Craveiro, Cronhjort, Maria, Dabrowski, Wojciech, Elhoufi, Ashraf, Ergan, Begum, Ferrer, Ricard, Freebairn, Ross, Fujii, Tomoko, Greco, Massimiliano, van Haren, Frank M. P., Hildebrandt, Thomas ... Eck, Ruben Julius (2025). Preferences for thromboprophylaxis in the intensive care unit: An international survey. Acta Anaesthesiologica Scandinavica, 69 (4) e70009, e70009. doi: 10.1111/aas.70009

Preferences for thromboprophylaxis in the intensive care unit: An international survey

2025

Conference Publication

Staged ECMO Reconfiguration as a Bridge to Recovery Following Pulmonary Endarterectomy for CTEPH With Large Thrombus Burden in a Septuagenarian

Raza, S., Sharma, V., Shekar, K. and Thomson, B. (2025). Staged ECMO Reconfiguration as a Bridge to Recovery Following Pulmonary Endarterectomy for CTEPH With Large Thrombus Burden in a Septuagenarian. ANZSCTS Annual Scientific Meeting, Noosa, QLD Australia, 7–9 November 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.02.087

Staged ECMO Reconfiguration as a Bridge to Recovery Following Pulmonary Endarterectomy for CTEPH With Large Thrombus Burden in a Septuagenarian

Funding

Current funding

  • 2025 - 2030
    Integrating sequencing technologies for bloodstream infection and sepsis diagnostics in critically-ill patients
    NHMRC MRFF Genomics Health Futures Mission
    Open grant
  • 2025 - 2030
    ROAD RCT: Resistance Optimised Antibiotic Dosing in critically ill patients - a Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2023 - 2028
    A national critical care research platform to ensure high quality sepsis care in Australian ICUs (MRFF EMCR led by Monash University)
    Monash University
    Open grant
  • 2022 - 2026
    PRecision Ecmo in CardIogenic Shock Evaluation: PRECISE Study (MRFF grant administered by Monash University)
    Monash University
    Open grant

Past funding

  • 2019
    Establishing UQ Centre for Clinical Research as the centre for Aerosol therapy in critical care by optimising particle size of aerosols for effective drug delivery.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Single Hand Used inTubaTing Laryngoscope Evaluation (SHUTTLE) Project

    Associate Advisor

    Other advisors: Professor Jeffrey Lipman

Completed supervision

Media

Enquiries

Contact Professor Kiran Shekar directly for media enquiries about their areas of expertise.

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