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Professor Kiran Shekar
Professor

Kiran Shekar

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Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 350 peer-reviewed journal articles, 60 conference abstracts, 14 book chapters and has delivered over 150 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

332 works between 2008 and 2026

21 - 40 of 332 works

2025

Journal Article

Missing the target in target trial emulation: the authors reply

Ling, Ryan Ruiyang, Chen, Ying, Shekar, Kiran, Brodie, Daniel, MacLaren, Graeme and Ramanathan, Kollengode (2025). Missing the target in target trial emulation: the authors reply. Critical Care, 29 (1) 311, 311-1. doi: 10.1186/s13054-025-05567-5

Missing the target in target trial emulation: the authors reply

2025

Journal Article

High-flow Oxygen and Nitric Oxide inhalation versus high-flow oxygen alone to prevent intubation in hypoxaemic Respiratory failure (HONOR): a pilot randomised controlled trial protocol

Churchill, Luke, Tronstad, Oystein, Hay, Karen, Thomas, Peter J. and Shekar, Kiran (2025). High-flow Oxygen and Nitric Oxide inhalation versus high-flow oxygen alone to prevent intubation in hypoxaemic Respiratory failure (HONOR): a pilot randomised controlled trial protocol. Pilot and Feasibility Studies, 11 (1) 149, 149. doi: 10.1186/s40814-025-01726-1

High-flow Oxygen and Nitric Oxide inhalation versus high-flow oxygen alone to prevent intubation in hypoxaemic Respiratory failure (HONOR): a pilot randomised controlled trial protocol

2025

Journal Article

Predictive Models for Mortality in Cardiogenic Shock: A Systematic Review and Meta-Analysis

Ng, Gwyneth Weng Yi, Low, Christopher Jer Wei, Ng, Kai Jie, Ling, Ryan Ruiyang, Chan, Siew Pang, Anbalakan, Kamalesh, Jung, Christian, Lin, Weiqin, Pilcher, David, Shekar, Kiran, Ramanathan, Kollengode and Lim, Shir Lynn (2025). Predictive Models for Mortality in Cardiogenic Shock: A Systematic Review and Meta-Analysis. Critical Care Medicine, 54 (1), 142-153. doi: 10.1097/ccm.0000000000006937

Predictive Models for Mortality in Cardiogenic Shock: A Systematic Review and Meta-Analysis

2025

Journal Article

Mortality trends for sepsis and septic shock among critically ill adults in Australia and New Zealand

Poole, Alexis P., Chaba, Anis, Bellomo, Rinaldo, Bailey, Michael, Deane, Adam, Delaney, Anthony, Eastwood, Glenn, Haines, Kimberley, Hammond, Naomi, Hensman, Tamishta, Higgins, Alisa, Jones, Daryl, McQuilten, Zoe, Mendis, Champ, Serpa Neto, Ary, Pilcher, David, Saxena, Manoj, Shekar, Kiran, Thompson, Kelly, Young, Paul J., Litton, Edward, Udy, Andrew A., Campbell, Lewis, Litton, Edward, Young, Paul, Cohen, Jeremy, Webb, Steve, Udy, Andrew, Poole, Alexis ... Cooper, David J. (2025). Mortality trends for sepsis and septic shock among critically ill adults in Australia and New Zealand. Intensive Care Medicine, 51 (12), 2318-2328. doi: 10.1007/s00134-025-08162-y

Mortality trends for sepsis and septic shock among critically ill adults in Australia and New Zealand

2025

Journal Article

Metabolic alkalosis acquired in intensive care: a retrospective cohort study

Goh, Gordon, Blank, Sebastiaan, Doola, Ra’eesa, Alder, Nelson, Ahuja, Abhilasha, Laupland, Kevin B., Tabah, Alexis, Shekar, Kiran, Kumar, Aashish, White, Kyle, Attokaran, Antony, Luke, Stephen, Whebell, Stephen, Garrett, Peter, Nesbitt, Alexander, McCullough, James, McIlroy, Philippa and Ramanan, Mahesh (2025). Metabolic alkalosis acquired in intensive care: a retrospective cohort study. Anaesthesia Critical Care and Pain Medicine, 44 (6) 101591, 1-6. doi: 10.1016/j.accpm.2025.101591

Metabolic alkalosis acquired in intensive care: a retrospective cohort study

2025

Journal Article

Persistent critical illness and long-term survival in cardiac surgery: a multicentre cohort study

Subramaniam, Ashwin, Ling, Ryan Ruiyang, Bonavia, William, Ramanathan, Kollengode, Ramanan, Mahesh, Shekar, Kiran and Pilcher, David (2025). Persistent critical illness and long-term survival in cardiac surgery: a multicentre cohort study. Anaesthesia Critical Care and Pain Medicine, 44 (6) 101593, 1-8. doi: 10.1016/j.accpm.2025.101593

Persistent critical illness and long-term survival in cardiac surgery: a multicentre cohort study

2025

Journal Article

The Association Between Frailty, Pao2/Fio2 Ratio, and Hospital Mortality: A Retrospective Registry-Based Cohort Study

Subramaniam, Ashwin, Ling, Ryan Ruiyang, Burrell, Aidan, Moran, Benjamin, Ramanan, Mahesh, Ramanathan, Kollengode, Reddy, Mallikarjuna Ponnapa, Pilcher, David and Shekar, Kiran (2025). The Association Between Frailty, Pao2/Fio2 Ratio, and Hospital Mortality: A Retrospective Registry-Based Cohort Study. Critical Care Medicine, 53 (12), 1-11. doi: 10.1097/ccm.0000000000006917

The Association Between Frailty, Pao2/Fio2 Ratio, and Hospital Mortality: A Retrospective Registry-Based Cohort Study

2025

Journal Article

Association between postoperative acute hypoxaemic respiratory failure and hospital mortality in patients undergoing cardiac surgery: a multicenter registry-based retrospective study

Subramaniam, Ashwin, Ling, Ryan Ruiyang, Raza, Samad, Pilcher, David and Shekar, Kiran (2025). Association between postoperative acute hypoxaemic respiratory failure and hospital mortality in patients undergoing cardiac surgery: a multicenter registry-based retrospective study. Anaesthesia Critical Care & Pain Medicine 101659, 101659. doi: 10.1016/j.accpm.2025.101659

Association between postoperative acute hypoxaemic respiratory failure and hospital mortality in patients undergoing cardiac surgery: a multicenter registry-based retrospective study

2025

Journal Article

Hemodynamics of veno-pulmonary extracorporeal membrane oxygenation with varying right ventricular function in a mock circulatory loop

Chand, Prashant, Yusuff, Hakeem, Zochios, Vasileios, Wickramarachchi, Avishka, Joyce, Christopher, Gregory, Shaun, Stephens, Andrew and Shekar, Kiran (2025). Hemodynamics of veno-pulmonary extracorporeal membrane oxygenation with varying right ventricular function in a mock circulatory loop. ASAIO Journal, 71 (9) 10.1097/MAT.0000000000002410, 727-735. doi: 10.1097/MAT.0000000000002410

Hemodynamics of veno-pulmonary extracorporeal membrane oxygenation with varying right ventricular function in a mock circulatory loop

2025

Journal Article

Anticoagulation strategy in veno-arterial extracorporeal membrane oxygenation in lung transplantation

Sandstrom, Timothy and Shekar, Kiran (2025). Anticoagulation strategy in veno-arterial extracorporeal membrane oxygenation in lung transplantation. Current Challenges in Thoracic Surgery, 7 7, 28-28. doi: 10.21037/ccts-25-7

Anticoagulation strategy in veno-arterial extracorporeal membrane oxygenation in lung transplantation

2025

Journal Article

Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data

Thao, Le Thi Phuong, Buscher, Hergen, Nguyen, Tri-Long, Martucci, Gennaro, Gratz, Johannes, Trummer, Georg, Schmidt, Matthieu, Gautier, Melchior, Serra, Alexis, Takeda, Koji, Pooth, Jan-Steffen, Rahn, Kevin, Geismann, Florian, Lubnow, Matthias, Retter, Andrew, Nair, Priya, Vlok, Ruan, Siriwardena, Maithri, Winearls, James, Walsham, James, Gattas, David, Aneman, Anders, Fulcher, Bentley, Newman, Sally, Reynolds, Claire, Arcadipane, Anthonio, Shekar, Kiran, Hodgson, Carol, Pellegrino, Vincent ... International ECMO Network (ECMONet) (2025). Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data. Critical Care, 29 (1) 360, 1-10. doi: 10.1186/s13054-025-05606-1

Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data

2025

Journal Article

Extracorporeal life support for adult patients with ARDS

Combes, Alain, Supady, Alexander, Abrams, Darryl, Agerstrand, Cara, Badulak, Jenelle, Camporota, Luigi, Fan, Eddy, Ferguson, Niall D., Fraser, John F., Hodgson, Carol, Jaber, Samir, MacLaren, Graeme, Patel, Brijesh V., Peek, Giles J., Schmidt, Matthieu, Shekar, Kiran, Slutsky, Arthur S. and Brodie, Daniel (2025). Extracorporeal life support for adult patients with ARDS. Intensive Care Medicine, 51 (9), 1674-1686. doi: 10.1007/s00134-025-08070-1

Extracorporeal life support for adult patients with ARDS

2025

Conference Publication

Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study

Ashby, A., Anstey, C., Attokaran, A., Siriwarden, M., Mullany, D., Kumar, A., Pryke, C., Laupland, K., Tabah, A., Shekar, K., Blank, S., Whebell, S., Luke, S., Raman, S., Garrett, P., McCullough, J., White, K. and Ramanan, M. (2025). Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study. 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Sydney, NSW Australia, 14-17 August 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.06.237

Epidemiology and Outcomes of Patients With Adult Congenital Heart Disease in Queensland Intensive Care Units: A Multicentre Retrospective Observational Study

2025

Journal Article

Acute kidney injury detection with additional point-of-care creatinine vs central laboratory serum creatinine measurement in critically ill patients

White, Kyle C., Meyer, Jason, Laupland, Kevin B., Senthuran, Siva, Shekar, Kiran, McCullough, James and Bellomo, Rinaldo (2025). Acute kidney injury detection with additional point-of-care creatinine vs central laboratory serum creatinine measurement in critically ill patients. Journal of Critical Care, 88 155050, 155050. doi: 10.1016/j.jcrc.2025.155050

Acute kidney injury detection with additional point-of-care creatinine vs central laboratory serum creatinine measurement in critically ill patients

2025

Journal Article

Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology network

Morales Castro, Diana, Al-Fares, Abdulrahman Abdullah, Paternoster, Gianluca, Lyster, Haifa, Hohlfelder, Benjamin, Arias Ortiz, Julian, Abdul-Aziz, Mohd Hafiz, Herr, Daniel, Alraish, Rawan, Ferre Contreras, Andrés, Palavecino, Marcela, Milella, Luigi, Watt, Kevin, Alkazemi, Afrah, Carini, Federico Carlos, Roberts, Jason A., Riera Del Brio, Jordi, Parra, Alba Pau, Kakar, Vivek, Dureau, Pauline, Duceppe, Marc-Alexandre, Alm, Mark, Cha, Stephanie, Shekar, Kiran, Dzierba, Amy L. and Extracorporeal Membrane Oxygenation Pharmacology Network (ECMOPharm Net) (2025). Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology network. Critical Care Medicine, 53 (11), e2246-e2260. doi: 10.1097/CCM.0000000000006806

Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology network

2025

Journal Article

Storage duration of packed red blood cells transfused during veno-venous extracorporeal membrane oxygenation is associated with elevated pulmonary artery pressure and lung injury in a sheep model

Temple, Fergal T., Simonova, Gabriela, Passmore, Margaret R., Foley, Samuel R., Diab, Sara D., Dunster, Kimble R., McDonald, Charles I., Shekar, Kiran, Fung, Yoke-Lin, Tung, John-Paul and Fraser, John F. (2025). Storage duration of packed red blood cells transfused during veno-venous extracorporeal membrane oxygenation is associated with elevated pulmonary artery pressure and lung injury in a sheep model. Critical Care, 29 (1) 240. doi: 10.1186/s13054-025-05438-z

Storage duration of packed red blood cells transfused during veno-venous extracorporeal membrane oxygenation is associated with elevated pulmonary artery pressure and lung injury in a sheep model

2025

Journal Article

Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation

Blank, Sebastiaan Paul, Blank, Ruth Miriam, Laupland, Kevin B., Tabah, Alexis, Gill, Denzil, Kumar, Aashish, White, Kyle, Attokaran, Antony, Luke, Stephen, Whebell, Stephen, Garrett, Peter, McCullough, James, McIlroy, Philippa, Ramanan, Mahesh, Keogh, Sam, Tyack, Zephanie, Gatton, Michelle, Nash, Ben, Blank, Sebastiaan, Dash, Sananta, Senthuran, Siva, Smart, Christopher, Taylor, Jennifer, Paasilahti, Anni, Reoch, Josephine, Poggenpoel, Jaco, Attokaran, Antony G., Anderson, Cameron, Lutshaba, Langa ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2025). Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation. Intensive Care Medicine, 51 (6), 1078-1086. doi: 10.1007/s00134-025-07979-x

Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation

2025

Journal Article

Right ventricular injury definition and management in veno-venous extracorporeal membrane oxygenation

Dugar, Siddharth Pawan, Sato, Ryota, Charlton, Matthew, Hasegawa, Daisuke, Antonini, Marta Velia, Nasa, Prashant, Yusuff, Hakeem, Schultz, Marcus J., Harnegie, Mary Pat, Ramanathan, Kollengode, Shekar, Kiran, Schmidt, Matthieu, Zochios, Vasileios, Duggal, Abhijit and on behalf of Protecting the Right Ventricle Network (PRORVnet) (2025). Right ventricular injury definition and management in veno-venous extracorporeal membrane oxygenation. ASAIO Journal, 71 (6), 482-491. doi: 10.1097/mat.0000000000002369

Right ventricular injury definition and management in veno-venous extracorporeal membrane oxygenation

2025

Journal Article

Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study

Zimsen, Tarren, Quick, Lachlan, White, Gentry, Costa-Pinto, Rahul, Whebell, Stephen, Meyer, Jason, McCullough, James, Shekar, Kiran, Laupland, Kevin B., Ramanan, Mahesh, Blank, Sebastiaan, Tabah, Alexis, Luke, Stephen, Garrett, Peter, Attokaran, Antony G., Kumar, Aashish and White, Kyle C. (2025). Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study. Critical Care and Resuscitation, 27 (2) 100112, 100112. doi: 10.1016/j.ccrj.2025.100112

Prevalence and characteristics of metaraminol usage in a large intensive care patient cohort. A multicentre, retrospective, observational study

2025

Journal Article

Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study

White, Kyle C., Bellomo, Rinaldo, Laupland, Kevin B., Gatton, Michelle L., Ostermann, Marlies, McIlroy, Philipa, Luke, Stephen, Garrett, Peter, Tabah, Alexis, Whebell, Stephen, Marella, Prashanti, McCullough, James, Shekar, Kiran, Attokaran, Antony G., Kumar, Aashish, Meyer, Jason, Sanderson, Barnaby, Serpa-Neto, Ary, Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David, White, Hayden ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2025). Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study. Journal of Critical Care, 87 155016, 1-9. doi: 10.1016/j.jcrc.2025.155016

Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: a multicentre, international study

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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