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Professor Kiran Shekar
Professor

Kiran Shekar

Email: 

Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 300 peer-reviewed articles, 60 conference abstracts, 14 book chapters and has delivered over 100 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

308 works between 2008 and 2025

21 - 40 of 308 works

2025

Journal Article

Mean arterial pressure in critically ill adults receiving vasopressors: a multicentre, observational study

White, Kyle C., Quick, Lachlan, Durkin, Zachary, McCullough, James, Laupland, Kevin B., Blank, Sebastiaan, Attokaran, Antony G., Kumar, Aashish, Shekar, Kiran, Garrett, Peter, Meyer, Jason, Tabah, Alexis, Ramanan, Mahesh, Luke, Stephen, Chaba, Anis, Bellomo, Rinaldo, Lamontagne, François, Young, Paul J., Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Phillipa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David, White, Hayden ... Keogh, Sam (2025). Mean arterial pressure in critically ill adults receiving vasopressors: a multicentre, observational study. Critical Care and Resuscitation, 27 (1) 100103, 1-8. doi: 10.1016/j.ccrj.2025.100103

Mean arterial pressure in critically ill adults receiving vasopressors: a multicentre, observational study

2025

Journal Article

Correction: Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults

Badulak, Jenelle, Abrams, Darryl, Luks, Andrew M., Zakhary, Bishoy, Conrad, Steven A., Bartlett, Robert, MacLaren, Graeme, Vercaemst, Leen, Lorusso, Roberto, Broman, Lars Mikael, Agerstrand, Cara, Price, Susanna, Combes, Alain, Peek, Giles, Fan, Eddy, Shekar, Kiran, Fraser, John, Brodie, Daniel and on behalf of the Extracorporeal Life Support Organization (ELSO) (2025). Correction: Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults. Intensive Care Medicine, 51 (3), 1-2. doi: 10.1007/s00134-025-07809-0

Correction: Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults

2025

Journal Article

Major psychiatric comorbidity among the critically ill: a multi-centred cohort study in Queensland

Flaws, Dylan, White, Kyle, Edwards, Felicity, Baker, Stuart, Senthuran, Siva, Ramanan, Mahesh, Attokaran, Antony G, Kumar, Aashish, McCullough, James, Shekar, Kiran, McIlroy, Philippa, Tabah, Alexis, Luke, Stephen, Garrett, Peter, Laupland, Kevin B, on behalf of the Queensland Critical Care Research Network (QCCRN), Denny, Kerina J, Tallott, Mandy, Marshall, Andrea, Moore, David, Sane, Sunil, Morrison, Lynette, Dipplesman, Pam, Nasser, Ahmad, Stewart, David, Shah, Vikram, Suliman, Adam, Meyer, Jason, Doola, Ra’eesa ... Keogh, Sam (2025). Major psychiatric comorbidity among the critically ill: a multi-centred cohort study in Queensland. BMC Psychiatry, 25 (1) 118, 1-8. doi: 10.1186/s12888-025-06520-0

Major psychiatric comorbidity among the critically ill: a multi-centred cohort study in Queensland

2025

Journal Article

Monitoring Hemostatic Function during Cardiac Surgery with Point-of-Care Viscoelastic Assays: A Narrative Review

Ong, Brandon Jin An, See Tow, Hui Xin, Fong, Alyssa Tze Wei, Ling, Ryan Ruiyang, Shekar, Kiran, Teoh, Kristine, Ti, Lian Kah, MacLaren, Graeme, Fan, Bingwen Eugene and Ramanathan, Kollengode (2025). Monitoring Hemostatic Function during Cardiac Surgery with Point-of-Care Viscoelastic Assays: A Narrative Review. Seminars in Thrombosis and Hemostasis. doi: 10.1055/s-0045-1802573

Monitoring Hemostatic Function during Cardiac Surgery with Point-of-Care Viscoelastic Assays: A Narrative Review

2025

Journal Article

Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study

Abdul-Aziz, Mohd H., Diehl, Arne, Liu, Xin, Cheng, Vesa, Corley, Amanda, Gilder, Eileen, Levkovich, Bianca, McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Pellegrino, Vincent, Wallis, Steven C., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2025). Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 69 (2) e0143524, 1-15. doi: 10.1128/aac.01435-24

Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study

2025

Journal Article

Impact of mild hypercapnia in critically ill patients with metabolic acidosis

Serpa Neto, Ary, Nasser, Ahmad, Marella, Prashanti, Fujii, Tomoko, Takahashi, Kazunari, Laupland, Kevin, Tabah, Alexis, Attokaran, Antony G., Kumar, Aashish, McCullough, James, Shekar, Kiran, Garrett, Peter, Blank, Sebastiaan, Senthuran, Siva, Luke, Stephen, McNamara, Mairead, Bellomo, Rinaldo and White, Kyle (2025). Impact of mild hypercapnia in critically ill patients with metabolic acidosis. Journal of Critical Care, 85 154936, 154936. doi: 10.1016/j.jcrc.2024.154936

Impact of mild hypercapnia in critically ill patients with metabolic acidosis

2025

Journal Article

Extracorporeal Life Support Organization 2024 Guideline for early rehabilitation or mobilization of adult patients on extracorporeal membrane oxygenation

Ramsey, Stephen, Shehatta, Ahmed Labib, Ramanathan, Kollengode, Shekar, Kiran, Brodie, Daniel, Diaz, Rodrigo, Roberts, Abigail, Cruz, Sherene, Hodgson, Carol, Zakhary, Bishoy, Reviewers:, Herr, Daniel, Ramanan, Raj, Broman, Lars, Riera, Jordi, O’Neil, Erika and Peek, Giles (2025). Extracorporeal Life Support Organization 2024 Guideline for early rehabilitation or mobilization of adult patients on extracorporeal membrane oxygenation. ASAIO Journal, 71 (3), 187-199. doi: 10.1097/mat.0000000000002375

Extracorporeal Life Support Organization 2024 Guideline for early rehabilitation or mobilization of adult patients on extracorporeal membrane oxygenation

2025

Journal Article

Hemodynamics of Veno-Pulmonary Extracorporeal Membrane Oxygenation with Varying Right Ventricular Function in a Mock Circulatory Loop

Chand, Prashant, Yusuff, Hakeem, Zochios, Vasileios, Wickramarachchi, Avishka, Joyce, Christopher, Gregory, Shaun, Stephens, Andrew and Shekar, Kiran (2025). Hemodynamics of Veno-Pulmonary Extracorporeal Membrane Oxygenation with Varying Right Ventricular Function in a Mock Circulatory Loop. ASAIO Journal, 71 (9) 10.1097/MAT.0000000000002410, 727-735. doi: 10.1097/MAT.0000000000002410

Hemodynamics of Veno-Pulmonary Extracorporeal Membrane Oxygenation with Varying Right Ventricular Function in a Mock Circulatory Loop

2025

Conference Publication

Postcardiotomy extracorporeal membrane oxygenation in patients older than 70 years: Characteristics, outcomes, and variables associated with mortality

Makhoul, Maged, Mariani, Silvia, van Bussel, Bas C.T., Wiedeman, Dominik, Saeed, Diyar, Di Mauro, Michele, Pozzi, Matteo, Botta, Luca, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Bunge, Jeroen J.H., Buscher, Hergen, Salazar, Leonardo, Meyns, Bart, Mazzeffi, Michael A., Sacha Matteucci, Marco L., Sponga, Sandro, MacLaren, Graeme, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo, Wang, I-wen, Jung, Jae-Seung ... Lorusso, Roberto (2025). Postcardiotomy extracorporeal membrane oxygenation in patients older than 70 years: Characteristics, outcomes, and variables associated with mortality. Elsevier B.V.. doi: 10.1016/j.xjon.2025.04.004

Postcardiotomy extracorporeal membrane oxygenation in patients older than 70 years: Characteristics, outcomes, and variables associated with mortality

2025

Journal Article

Postcardiotomy extracorporeal membrane oxygenation after elective, urgent, and emergency cardiac operations: Insights from the PELS observational study

Mariani, Silvia, Perazzo, Alvaro, De Piero, Maria Elena, van Bussel, Bas C.T., Di Mauro, Michele, Wiedemann, Dominik, Lehmann, Sven, Pozzi, Matteo, Loforte, Antonio, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Bunge, Jeroen J.H., Sriranjan, Kogulan, Salazar, Leonardo, Meyns, Bart, Mazzeffi, Michael A., Matteucci, Sacha, Sponga, Sandro, MacLaren, Graeme, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo, Wang, I-wen ... Lorusso, Roberto (2025). Postcardiotomy extracorporeal membrane oxygenation after elective, urgent, and emergency cardiac operations: Insights from the PELS observational study. JTCVS Open, 24, 280-310. doi: 10.1016/j.xjon.2025.01.018

Postcardiotomy extracorporeal membrane oxygenation after elective, urgent, and emergency cardiac operations: Insights from the PELS observational study

2025

Journal Article

Propofol and fentanyl pharmacokinetics and pharmacodynamics in extracorporeal membrane oxygenation

Morales Castro, Diana, Balzani, Eleonora, Abdul-Aziz, M. Hafiz, Hernandez-Mitre, Maria Patricia, Wong, Irene, Turgeon, Julien, Tisminetzky, Manuel, Jurado-Camacho, Felipe, Morris, Idunn, Dresser, Linda, Granton, John, Uetrecht, Jack, Pang, K. Sandy, Chen, Eric, Shekar, Kiran and Fan, Eddy (2025). Propofol and fentanyl pharmacokinetics and pharmacodynamics in extracorporeal membrane oxygenation. Annals of the American Thoracic Society, 22 (1), 121-129. doi: 10.1513/annalsats.202407-795oc

Propofol and fentanyl pharmacokinetics and pharmacodynamics in extracorporeal membrane oxygenation

2024

Journal Article

Intensive care unit-onset bloodstream infections represent a distinct category of hospital-onset infections: A multicentre, retrospective cohort study. Queensland Critical Care Network (QCCRN)

Tabah, Alexis, Edwards, Felicity, Ramanan, Mahesh, White, Kyle C., Shekar, Kiran, Mcilroy, Philippa, Attokaran, Antony, Senthuran, Siva, Mccullough, James, Kumar, Aashish, Luke, Stephen, Bhadange, Neeraj, Garrett, Peter and Laupland, Kevin B. (2024). Intensive care unit-onset bloodstream infections represent a distinct category of hospital-onset infections: A multicentre, retrospective cohort study. Queensland Critical Care Network (QCCRN). Journal of the Association of Medical Microbiology and Infectious Disease Canada (Jammi), 9 (4), 229-238. doi: 10.3138/jammi-2024-0023

Intensive care unit-onset bloodstream infections represent a distinct category of hospital-onset infections: A multicentre, retrospective cohort study. Queensland Critical Care Network (QCCRN)

2024

Journal Article

Rapid uptake of adjunctive corticosteroids for critically ill adults with septic shock following publication of ADRENAL trial. a multicenter, retrospective analysis of prescribing practices in Queensland Intensive Care Units

White, Kyle C., Chaba, Anis, Meyer, Jason, Ramanan, Mahesh, Tabah, Alexis, Attokaran, Antony G., Kumar, Aashish, McCullough, James, Shekar, Kiran, Garrett, Peter, McIlroy, Philippa, Senthuran, Siva, Luke, Stephen, Laupland, Kevin B. and on behalf of the Queensland Critical Care Research Network (QCCRN) (2024). Rapid uptake of adjunctive corticosteroids for critically ill adults with septic shock following publication of ADRENAL trial. a multicenter, retrospective analysis of prescribing practices in Queensland Intensive Care Units. Anaesthesia Critical Care and Pain Medicine, 43 (6) 101435, 1-11. doi: 10.1016/j.accpm.2024.101435

Rapid uptake of adjunctive corticosteroids for critically ill adults with septic shock following publication of ADRENAL trial. a multicenter, retrospective analysis of prescribing practices in Queensland Intensive Care Units

2024

Journal Article

Outcomes of adult patients With COVID-19 transitioning from venovenous to venoarterial or hybrid extracorporeal membrane oxygenation in the extracorporeal life support organization registry

Nguyen, Khoa, Altibi, Ahmed, Prasad, Pooja, Mukundan, Srini, Shekar, Kiran, Ramanathan, Kollengode and Zakhary, Bishoy (2024). Outcomes of adult patients With COVID-19 transitioning from venovenous to venoarterial or hybrid extracorporeal membrane oxygenation in the extracorporeal life support organization registry. ASAIO Journal, 70 (12), 1040-1045. doi: 10.1097/mat.0000000000002243

Outcomes of adult patients With COVID-19 transitioning from venovenous to venoarterial or hybrid extracorporeal membrane oxygenation in the extracorporeal life support organization registry

2024

Journal Article

ICU-acquired hypernatremia: prevalence, patient characteristics, trajectory, risk factors, and outcomes

Nasser, Ahmad, Chaba, Anis, Laupland, Kevin B., Ramanan, Mahesh, Tabah, Alexis, Attokaran, Antony G., Kumar, Aashish, McCullough, James, Shekar, Kiran, Garrett, Peter, McIlroy, Philippa, Luke, Stephen, Senthuran, Siva, Bellomo, Rinaldo, White, Kyle C., Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Philippa, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David, Sane, Sunil, Kumar, Aashish, Morrison, Lynette, Dipplesman, Pam ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2024). ICU-acquired hypernatremia: prevalence, patient characteristics, trajectory, risk factors, and outcomes. Critical Care and Resuscitation, 26 (4), 303-310. doi: 10.1016/j.ccrj.2024.09.003

ICU-acquired hypernatremia: prevalence, patient characteristics, trajectory, risk factors, and outcomes

2024

Journal Article

Timing of adjunctive vasopressin initiation for septic shock patients and hospital mortality: a multicentre observational study

White, Kyle C., Costa-Pinto, Rahul, Chaba, Anis, McIlroy, Philippa, Senthuran, Siva, Luke, Stephen, Attokaran, Antony G., Garrett, Peter, Ramanan, Mahesh, Tabah, Alexis, Shekar, Kiran, Laupland, Kevin B., White, Hayden, McCullough, James, Udy, Andrew, Eastwood, Glenn, Bellomo, Rinaldo, Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Pip, Nash, Ben, McCullough, James, Denny, Kerina J., Tallott, Mandy, Marshall, Andrea, Moore, David, White, Hayden, Sane, Sunil ... Keogh, Sam (2024). Timing of adjunctive vasopressin initiation for septic shock patients and hospital mortality: a multicentre observational study. Critical Care and Resuscitation, 26 (4), 295-302. doi: 10.1016/j.ccrj.2024.09.002

Timing of adjunctive vasopressin initiation for septic shock patients and hospital mortality: a multicentre observational study

2024

Journal Article

Features and outcomes of females and males requiring postcardiotomy extracorporeal life support

Mariani, Silvia, Ravaux, Justine Mafalda, van Bussel, Bas C.T., De Piero, Maria Elena, van Kruijk, Sander M.J., Schaefer, Anne-Kristin, Wiedemann, Dominik, Saeed, Diyar, Pozzi, Matteo, Loforte, Antonio, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Bunge, Jeroen J.H., Buscher, Hergen, Salazar, Leonardo, Meyns, Bart, Mazzeffi, Michael A., Matteucci, Sacha, Sponga, Sandro, Sorokin, Vitaly, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo ... Solinas, Marco (2024). Features and outcomes of females and males requiring postcardiotomy extracorporeal life support. The Journal of Thoracic and Cardiovascular Surgery, 168 (6), 1701-1711.e30. doi: 10.1016/j.jtcvs.2024.04.033

Features and outcomes of females and males requiring postcardiotomy extracorporeal life support

2024

Journal Article

Sepsis‐associated acute kidney injury in patients with chronic kidney disease: patient characteristics, prevalence, timing, trajectory, treatment and associated outcomes

White, Kyle C., Bellomo, Rinaldo, Tabah, Alexis, Attokaran, Antony G., White, Hayden, McCullough, James, Shekar, Kiran, Ramanan, Mahesh, Garrett, Peter, McIlroy, Philippa, Senthuran, Siva, Luke, Stephen, Serpa‐Neto, Ary, Larsen, Tom, Laupland, Kevin B. and the Queensland Critical Care Research Network (QCCRN) (2024). Sepsis‐associated acute kidney injury in patients with chronic kidney disease: patient characteristics, prevalence, timing, trajectory, treatment and associated outcomes. Nephrology, 29 (12), 838-848. doi: 10.1111/nep.14392

Sepsis‐associated acute kidney injury in patients with chronic kidney disease: patient characteristics, prevalence, timing, trajectory, treatment and associated outcomes

2024

Journal Article

Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults

Badulak, Jenelle, Abrams, Darryl, Luks, Andrew M., Zakhary, Bishoy, Conrad, Steven A., Bartlett, Robert, MacLaren, Graeme, Vercaemst, Leen, Lorusso, Roberto, Broman, Lars Mikael, Agerstrand, Cara, Price, Susanna, Combes, Alain, Peek, Giles, Fan, Eddy, Shekar, Kiran, Fraser, John and Brodie, Daniel (2024). Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults. Intensive Care Medicine, 50 (12), 1994-2004. doi: 10.1007/s00134-024-07645-8

Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults

2024

Journal Article

Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study

Ling, Ryan Ruiyang, Ponnapa Reddy, Mallikarjuna, Subramaniam, Ashwin, Moran, Benjamin, Ramanathan, Kollengode, Ramanan, Mahesh, Burrell, Aidan, Pilcher, David and Shekar, Kiran (2024). Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study. Intensive Care Medicine, 50 (11), 1861-1872. doi: 10.1007/s00134-024-07609-y

Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study

Funding

Current funding

  • 2025 - 2030
    Integrating sequencing technologies for bloodstream infection and sepsis diagnostics in critically-ill patients
    NHMRC MRFF Genomics Health Futures Mission
    Open grant
  • 2025 - 2030
    ROAD RCT: Resistance Optimised Antibiotic Dosing in critically ill patients - a Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2023 - 2028
    A national critical care research platform to ensure high quality sepsis care in Australian ICUs (MRFF EMCR led by Monash University)
    Monash University
    Open grant
  • 2022 - 2026
    PRecision Ecmo in CardIogenic Shock Evaluation: PRECISE Study (MRFF grant administered by Monash University)
    Monash University
    Open grant

Past funding

  • 2019
    Establishing UQ Centre for Clinical Research as the centre for Aerosol therapy in critical care by optimising particle size of aerosols for effective drug delivery.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Single Hand Used inTubaTing Laryngoscope Evaluation (SHUTTLE) Project

    Associate Advisor

    Other advisors: Professor Jeffrey Lipman

Completed supervision

Media

Enquiries

Contact Professor Kiran Shekar directly for media enquiries about their areas of expertise.

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