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Professor Kiran Shekar
Professor

Kiran Shekar

Email: 

Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 300 peer-reviewed articles, 60 conference abstracts, 14 book chapters and has delivered over 100 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

308 works between 2008 and 2025

81 - 100 of 308 works

2023

Journal Article

Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest in Australia: a narrative review

Dennis, Mark, Shekar, Kiran, Burrell, Aidan J. C., Austin, Danielle, Anderson, David, Bernard, Stephen, Burns, Brian, Buscher, Hergen, Christie, Gayle, Collett, Luke, Coggins, Andrew, Doan, Tan, Dhanani, Jayesh, Finn, Judith, Fisher, Caleb, Ferguson, Ian, Forrest, Paul, Gill, Denzil, Granger, Emily, Higgins, Lisa, Hodgson, Carol, Jones, Daryl, Kruit, Natalie, La Gerche, Andre, Marasco, Silvana, Maruno, Kevin, McCanny, Peter, Moylan, Emily, Nanjayya, Vinod ... Winearls, James (2023). Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest in Australia: a narrative review. Medical Journal of Australia, 220 (1), 46-53. doi: 10.5694/mja2.52130

Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest in Australia: a narrative review

2023

Journal Article

Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with cardiac arrest: a comparative meta-analysis and trial sequential analysis

Low, Christopher Jer Wei, Ramanathan, Kollengode, Ling, Ryan Ruiyang, Ho, Maxz Jian Chen, Chen, Ying, Lorusso, Roberto, MacLaren, Graeme, Shekar, Kiran and Brodie, Daniel (2023). Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with cardiac arrest: a comparative meta-analysis and trial sequential analysis. The Lancet Respiratory Medicine, 11 (10), 883-893. doi: 10.1016/s2213-2600(23)00137-6

Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with cardiac arrest: a comparative meta-analysis and trial sequential analysis

2023

Journal Article

Heterogeneity in clinical practices for post‐cardiotomy extracorporeal life support: a pilot survey from the PELS‐1 multicenter study

Mariani, Silvia, Bari, Gabor, Ravaux, Justine M., van Bussel, Bas C. T., De Piero, Maria Elena, Schaefer, Ann‐Kristin, Jawad, Khalil, Pozzi, Matteo, Loforte, Antonio, Kalampokas, Nikolaos, Jankuviene, Agne, Flecher, Erwan, Hou, Xiaotong, Bunge, Jeroen J. H., Sriranjan, Kogulan, Salazar, Leonardo, Meyns, Bart, Mazzeffi, Michael A., Matteucci, Sacha, Sponga, Sandro, Ramanathan, Kollengode, Costetti, Alessandro, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Schmid, Chistof, Raffa, Giuseppe Maria, Castillo, Roberto, Wang, I‐wen ... Roberto Lorusso1, the PELS‐1 Investigators (2023). Heterogeneity in clinical practices for post‐cardiotomy extracorporeal life support: a pilot survey from the PELS‐1 multicenter study. Artificial Organs, 47 (10), 1641-1653. doi: 10.1111/aor.14601

Heterogeneity in clinical practices for post‐cardiotomy extracorporeal life support: a pilot survey from the PELS‐1 multicenter study

2023

Journal Article

Determinants of 90-day case fatality among older patients admitted to intensive care units: A retrospective cohort study

Marella, Prashanti, Ramanan, Mahesh, Shekar, Kiran, Tabah, Alexis and Laupland, Kevin B. (2023). Determinants of 90-day case fatality among older patients admitted to intensive care units: A retrospective cohort study. Australian Critical Care, 37 (1), 18-24. doi: 10.1016/j.aucc.2023.07.039

Determinants of 90-day case fatality among older patients admitted to intensive care units: A retrospective cohort study

2023

Journal Article

Blend to limit oxgyen in ECMO: a randomised controlled registry trial: study protocol and statistical analysis plan

Burrell, Aidan, Ng, Sze, Ottosen, Kelly, Bailey, Michael, Buscher, Hergen, Fraser, John, Udy, Andrew, Gattas, David, Totaro, Richard, Bellomo, Rinaldo, Forrest, Paul, Martin, Emma, Reid, Liadain, Ziegenfuss, Marc, Eastwood, Glenn, Higgins, Alisa, Hodgson, Carol, Litton, Edward, Nair, Priya, Orford, Neil, Pellegrino, Vince, Shekar, Kiran, Trapani, Tony and Pilcher, David (2023). Blend to limit oxgyen in ECMO: a randomised controlled registry trial: study protocol and statistical analysis plan. Critical Care and Resuscitation, 25 (3), 118-125. doi: 10.1016/j.ccrj.2023.06.001

Blend to limit oxgyen in ECMO: a randomised controlled registry trial: study protocol and statistical analysis plan

2023

Conference Publication

Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomised controlled trials and propensity score matched studies

Wei Low, Christopher Jer, Ruiyang Ling, Ryan, Xin Ling Lau, Michele Petrova, Hui Liu, Nigel Sheng, Tan, Melissa, Seng Tan, Chuen, Lynn Lim, Shir, Rochwerg, Bram, Combes, Alain, Brodie, Daniel, Shekar, Kiran, Price, Susanna, MacLaren, Graeme and Ramanathan, Kollengode (2023). Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomised controlled trials and propensity score matched studies. 34th Annual ELSO Conference, Seattle, WA United States, 28 September - 1 October 2023. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mat.0000990548.99398.1d

Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomised controlled trials and propensity score matched studies

2023

Conference Publication

Early versus late extracorporeal cardiopulmonary resuscitation for in-hospital cardiac arrest (RAPID): a target-trial emulation of the ELSO registry

Ruiyang Ling, Ryan, Gu, Tianyuan, Choo Tai, Bee, Seung Jung, Jae, Anders, Marc, Shekar, Kiran, Brodie, Daniel, MacLaren, Graeme and Ramanathan, Kollengode (2023). Early versus late extracorporeal cardiopulmonary resuscitation for in-hospital cardiac arrest (RAPID): a target-trial emulation of the ELSO registry. 34th Annual ELSO Conference, Seattle, WA United States, 27 September - 1 October 2023. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mat.0000990716.55505.ec

Early versus late extracorporeal cardiopulmonary resuscitation for in-hospital cardiac arrest (RAPID): a target-trial emulation of the ELSO registry

2023

Journal Article

Sepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter, observational study

White, Kyle C., Serpa-Neto, Ary, Hurford, Rod, Clement, Pierre, Laupland, Kevin B., See, Emily, McCullough, James, White, Hayden, Shekar, Kiran, Tabah, Alexis, Ramanan, Mahesh, Garrett, Peter, Attokaran, Antony G., Luke, Stephen, Senthuran, Siva, McIlroy, Philippa, Bellomo, Rinaldo, Ramanan, Mahesh, Marella, Prashanti, Young, Patrick, McIlroy, Pip, Nash, Ben, McCullough, James, Tallott, Mandy, Marshall, Andrea, Moore, David, White, Hayden, Sane, Sunil, Morrison, Lynette ... on behalf of the Queensland Critical Care Research Network (QCCRN) (2023). Sepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter, observational study. Intensive Care Medicine, 49 (9), 1079-1089. doi: 10.1007/s00134-023-07138-0

Sepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter, observational study

2023

Journal Article

Patient and management variables associated with survival after postcardiotomy extracorporeal membrane oxygenation in adults: The PELS‐1 Multicenter Cohort Study

Mariani, Silvia, Heuts, Samuel, van Bussel, Bas C. T., Di Mauro, Michele, Wiedemann, Dominik, Saeed, Diyar, Pozzi, Matteo, Loforte, Antonio, Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Bunge, Jeroen J. H., Buscher, Hergen, Salazar, Leonardo, Meyns, Bart, Herr, Daniel, Matteucci, Marco L. Sacha, Sponga, Sandro, MacLaren, Graeme, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo, Wang, I‐wen, Jung, Jae‐Seung ... on behalf of the PELS-1 Investigators (2023). Patient and management variables associated with survival after postcardiotomy extracorporeal membrane oxygenation in adults: The PELS‐1 Multicenter Cohort Study. Journal of the American Heart Association, 12 (14) e029609, e029609. doi: 10.1161/jaha.123.029609

Patient and management variables associated with survival after postcardiotomy extracorporeal membrane oxygenation in adults: The PELS‐1 Multicenter Cohort Study

2023

Journal Article

Is it time to put low-flow extracorporeal carbon dioxide removal to REST?*

Worku, Elliott, Schmidt, Matthieu and Shekar, Kiran (2023). Is it time to put low-flow extracorporeal carbon dioxide removal to REST?*. Critical Care Medicine, 51 (7), 973-976. doi: 10.1097/ccm.0000000000005889

Is it time to put low-flow extracorporeal carbon dioxide removal to REST?*

2023

Journal Article

Venovenous extracorporeal CO2 removal to support ultraprotective ventilation in moderate-severe acute respiratory distress syndrome: a systematic review and meta-analysis of the literature

Worku, Elliott, Brodie, Daniel, Ling, Ryan Ruiyang, Ramanathan, Kollengode, Combes, Alain and Shekar, Kiran (2023). Venovenous extracorporeal CO2 removal to support ultraprotective ventilation in moderate-severe acute respiratory distress syndrome: a systematic review and meta-analysis of the literature. Perfusion, 38 (5), 1062-1079. doi: 10.1177/02676591221096225

Venovenous extracorporeal CO2 removal to support ultraprotective ventilation in moderate-severe acute respiratory distress syndrome: a systematic review and meta-analysis of the literature

2023

Journal Article

Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation

Lyster, Haifa, Shekar, Kiran, Watt, Kevin, Reed, Anna, Roberts, Jason A. and Abdul-Aziz, Mohd-Hafiz (2023). Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation. Clinical Pharmacokinetics, 62 (7), 931-942. doi: 10.1007/s40262-023-01264-0

Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation

2023

Journal Article

Expert consensus statement on venovenous extracorporeal membrane oxygenation ECMO for COVID-19 severe ARDS: an international Delphi study

Rabie, Ahmed A., Elhazmi, Alyaa, Azzam, Mohamed H., Abdelbary, Akram, Labib, Ahmed, Combes, Alain, Zakhary, Bishoy, MacLaren, Graeme, Barbaro, Ryan P., Peek, Giles J., Antonini, Marta Velia, Shekar, Kiran, Al‐Fares, Abdulrahman, Oza, Pranay, Mehta, Yatin, Alfoudri, Huda, Ramanathan, Kollengode, Ogino, Mark, Raman, Lakshmi, Paden, Matthew, Brodie, Daniel and Bartlett, Robert (2023). Expert consensus statement on venovenous extracorporeal membrane oxygenation ECMO for COVID-19 severe ARDS: an international Delphi study. Annals of Intensive Care, 13 (1) 36, 1-12. doi: 10.1186/s13613-023-01126-9

Expert consensus statement on venovenous extracorporeal membrane oxygenation ECMO for COVID-19 severe ARDS: an international Delphi study

2023

Journal Article

Excess burden of critical illness related to inflammatory bowel disease

Laupland, Kevin B, Shekar, Kiran, Tabah, Alexis, Clement, Pierre, Edwards, Felicity and Ramanan, Mahesh (2023). Excess burden of critical illness related to inflammatory bowel disease. Internal Medicine Journal, 53 (5), 812-818. doi: 10.1111/imj.15672

Excess burden of critical illness related to inflammatory bowel disease

2023

Journal Article

Veno-Pulmonary Arterial Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Distress Syndrome: Should We Consider Mechanical Support of the Pulmonary Circulation From the Outset?

Zochios, Vasileios, Yusuff, Hakeem, Antonini, Marta Velia, Schmidt, Matthieu, Shekar, Kiran and for Protecting the Right Ventricle Network (PRORVnet) (2023). Veno-Pulmonary Arterial Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Distress Syndrome: Should We Consider Mechanical Support of the Pulmonary Circulation From the Outset?. ASAIO Journal, 69 (6), 511-518. doi: 10.1097/mat.0000000000001930

Veno-Pulmonary Arterial Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Distress Syndrome: Should We Consider Mechanical Support of the Pulmonary Circulation From the Outset?

2023

Journal Article

The Relation between Obesity and Mortality in Postcardiotomy Veno-arterial Membrane Oxygenation

Heuts, Samuel, Mariani, Silvia, van Bussel, C.T., Boeken, Udo, Samalavicius, Robertas, Bounader, Karl, Hou, Xiaotong, Bunge, Jeroen J.H., Sriranjan, Kogulan, Wiedeman, Dominik, Saeed, Diyar, Pozzi, Matteo, Loforte, Antonio, Salazar, Leonardo, Meyns, Bart, Mazzeffi, Michael A., Matteucci, Sacha, Sponga, Sandro, Sorokin, Vitaly, Russo, Claudio, Formica, Francesco, Sakiyalak, Pranya, Fiore, Antonio, Camboni, Daniele, Raffa, Giuseppe Maria, Diaz, Rodrigo, Wang, I-wen, Jung, Jae-Seung, Belohlavek, Jan ... on behalf of the PELS-1 Investigators (2023). The Relation between Obesity and Mortality in Postcardiotomy Veno-arterial Membrane Oxygenation. The Annals of Thoracic Surgery, 116 (1), 147-154. doi: 10.1016/j.athoracsur.2023.03.025

The Relation between Obesity and Mortality in Postcardiotomy Veno-arterial Membrane Oxygenation

2023

Journal Article

Institution-free days after critical illness: A multicenter retrospective study

Marella, Prashanti, Laupland, Kevin B., Shekar, Kiran, Tabah, Alexis, Edwards, Felicity and Ramanan, Mahesh (2023). Institution-free days after critical illness: A multicenter retrospective study. Journal of Critical Care, 74 154253, 1-7. doi: 10.1016/j.jcrc.2023.154253

Institution-free days after critical illness: A multicenter retrospective study

2023

Journal Article

Haematological trends and transfusion during adult extracorporeal membrane oxygenation: a single centre study

Worku, Elliott T., Win, April M., Parmar, Dinesh, Anstey, Chris and Shekar, Kiran (2023). Haematological trends and transfusion during adult extracorporeal membrane oxygenation: a single centre study. Journal of Clinical Medicine, 12 (7) 2629, 1-18. doi: 10.3390/jcm12072629

Haematological trends and transfusion during adult extracorporeal membrane oxygenation: a single centre study

2023

Journal Article

90-day case-fatality in critically ill patients with chronic liver disease influenced by presence of portal hypertension, results from a multicentre retrospective cohort study

White, Kyle, Tabah, Alexis, Ramanan, Mahesh, Shekar, Kiran, Edwards, Felicity and Laupland, Kevin B. (2023). 90-day case-fatality in critically ill patients with chronic liver disease influenced by presence of portal hypertension, results from a multicentre retrospective cohort study. Journal of Intensive Care Medicine, 38 (1), 1-10. doi: 10.1177/08850666221100408

90-day case-fatality in critically ill patients with chronic liver disease influenced by presence of portal hypertension, results from a multicentre retrospective cohort study

2023

Book Chapter

Ethical challenges and quality assurance of extracorporeal membrane oxygenation

Ramanathan, Kollengode, Shekar, Kiran and Dhundi, Ujwal (2023). Ethical challenges and quality assurance of extracorporeal membrane oxygenation. Cardiopulmonary bypass: advances in extracorporeal life support. (pp. 1023-1031) Amsterdam: Academic Press. doi: 10.1016/b978-0-443-18918-0.00065-6

Ethical challenges and quality assurance of extracorporeal membrane oxygenation

Funding

Current funding

  • 2025 - 2030
    Integrating sequencing technologies for bloodstream infection and sepsis diagnostics in critically-ill patients
    NHMRC MRFF Genomics Health Futures Mission
    Open grant
  • 2025 - 2030
    ROAD RCT: Resistance Optimised Antibiotic Dosing in critically ill patients - a Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2023 - 2028
    A national critical care research platform to ensure high quality sepsis care in Australian ICUs (MRFF EMCR led by Monash University)
    Monash University
    Open grant
  • 2022 - 2026
    PRecision Ecmo in CardIogenic Shock Evaluation: PRECISE Study (MRFF grant administered by Monash University)
    Monash University
    Open grant

Past funding

  • 2019
    Establishing UQ Centre for Clinical Research as the centre for Aerosol therapy in critical care by optimising particle size of aerosols for effective drug delivery.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Single Hand Used inTubaTing Laryngoscope Evaluation (SHUTTLE) Project

    Associate Advisor

    Other advisors: Professor Jeffrey Lipman

Completed supervision

Media

Enquiries

Contact Professor Kiran Shekar directly for media enquiries about their areas of expertise.

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