Overview
Background
Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 350 peer-reviewed journal articles, 60 conference abstracts, 14 book chapters and has delivered over 150 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.
Availability
- Professor Kiran Shekar is:
- Available for supervision
- Media expert
Research interests
-
Extracorporeal membrane oxygenation
-
Respiratory failure and minimising the burden of invasive mechanical ventilation
-
PK/PD on Extracorporeal membrane oxygenation support
-
Cardiogenic Shock and Mechanical Circulatory Support
-
Microcirculation on temporary Mechanical Circulatory Support
-
Building a budget intensive care unit to improve intensive care access in resource poor countries
-
Standardising ECMO education to bridge the variability in global ECMO outcomes
Works
Search Professor Kiran Shekar’s works on UQ eSpace
2022
Journal Article
Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers
Subramaniam, Ashwin, Reddy, Mallikarjuna, Kadam, Umesh, Zubarev, Alexander, Lim, Zheng, Anstey, Chris, Bihari, Shailesh, Haji, Jumana, Luo, Jinghang, Mitra, Saikat, Ramanathan, Kollengode, Rajamani, Arvind, Rubulotta, Francesca, Svensk, Erik and Shekar, Kiran (2022). Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers. Australian Critical Care, 35 (4), 415-423. doi: 10.1016/j.aucc.2021.06.015
2022
Journal Article
SARS-CoV-2 transmission risk to healthcare workers performing tracheostomies: a systematic review
Subramaniam, Ashwin, Lim, Zheng Jie, Ponnapa Reddy, Mallikarjuna, Mitchell, Hayden and Shekar, Kiran (2022). SARS-CoV-2 transmission risk to healthcare workers performing tracheostomies: a systematic review. ANZ Journal of Surgery, 92 (7-8), 1614-1625. doi: 10.1111/ans.17814
2022
Journal Article
Reply Letter to the Editor Regarding the ELSO Interim Guidelines for Veno-Arterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients
Lorusso, Roberto, Bartlett, Robert H., Shekar, Kiran, MacLaren, Graeme, Schmidt, Matthieu, Pellegrino, Vincent, Meyns, Bart, Haft, Jonathan, Vercaemst, Leen, Pappalardo, Federico, Bermudez, Christian, Belohlavek, Jan, Hou, Xiaotong, Boeken, Udo, Castillo, Roberto, Donker, Dirk W., Abrams, Darryl, Ranucci, Marco, Hryniewicz, Kasia, Chavez, Ivan, Chen, Yih-Sharng, Salazar, Leonardo and Whitman, Glenn (2022). Reply Letter to the Editor Regarding the ELSO Interim Guidelines for Veno-Arterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients. ASAIO Journal, 68 (6), E111-E112. doi: 10.1097/MAT.0000000000001701
2022
Journal Article
Development of a standardized assessment of simulation-based extracorporeal membrane oxygenation educational courses
Said, Ahmed S., Cooley, Elaine, Moore, Elizabeth A., Shekar, Kiran, Maul, Timothy M., Kollengode, Ramanathan and Zakhary, Bishoy (2022). Development of a standardized assessment of simulation-based extracorporeal membrane oxygenation educational courses. ATS Scholar, 3 (2), 242-257. doi: 10.34197/ats-scholar.2021-0068OC
2022
Journal Article
Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)
Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Levkovich, Bianca J., Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Roberts, Jason A., Shekar, Kiran, Fraser, John F. and ASAP ECMO Investigators (2022). Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Anaesthesia Critical Care and Pain Medicine, 41 (3) 101080, 1-6. doi: 10.1016/j.accpm.2022.101080
2022
Journal Article
Evolving outcomes of extracorporeal membrane oxygenation during the first 2 years of the COVID-19 pandemic: a systematic review and meta-analysis
Ling, Ryan Ruiyang, Ramanathan, Kollengode, Sim, Jackie Jia Lin, Wong, Suei Nee, Chen, Ying, Amin, Faizan, Fernando, Shannon M., Rochwerg, Bram, Fan, Eddy, Barbaro, Ryan P., MacLaren, Graeme, Shekar, Kiran and Brodie, Daniel (2022). Evolving outcomes of extracorporeal membrane oxygenation during the first 2 years of the COVID-19 pandemic: a systematic review and meta-analysis. Critical Care, 26 (1) 147, 1-13. doi: 10.1186/s13054-022-04011-2
2022
Journal Article
Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis
Li Bassi, Gianluigi, Gibbons, Kristen, Suen, Jacky Y., Dalton, Heidi J., White, Nicole, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Laffey, John G., Fan, Eddy, Fanning, Jonathon P., Panigada, Mauro, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Esperatti, Mariano, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Ogino, Mark, Pelosi, Paolo ... The COVID-19 Critical Care Consortium (2022). Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis. Critical Care, 26 (1) 141, 141. doi: 10.1186/s13054-022-03983-5
2022
Journal Article
Extracorporeal membrane oxygenation during pregnancy and peripartal. An international retrospective multicenter study
Malfertheiner, S. Fill, Brodie, D., Burrell, A., Taccone, F. S., Broman, L. M., Shekar, K., Agerstrand, C. L., Serra, A. L., Fraser, J. and Malfertheiner, M. V. (2022). Extracorporeal membrane oxygenation during pregnancy and peripartal. An international retrospective multicenter study. Perfusion, 38 (5), 1-7. doi: 10.1177/02676591221090668
2022
Journal Article
Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study
Urner, Martin, Barnett, Adrian G., Bassi, Gianluigi Li, Brodie, Daniel, Dalton, Heidi J., Ferguson, Niall D., Heinsar, Silver, Hodgson, Carol L., Peek, Giles, Shekar, Kiran, Suen, Jacky Y., Fraser, John F., Fan, Eddy, COVID-19 Critical Care Consortium Investigators and Obonyo, Nchafatso (2022). Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study. BMJ, 377 e068723, e068723. doi: 10.1136/bmj-2021-068723
2022
Journal Article
Extracorporeal life support organization guidelines for fluid overload, acute kidney injury, and electrolyte management
Bridges, Brian C., Dhar, Archana, Ramanathan, Kollengode, Steflik, Heidi J., Schmidt, Matthieu and Shekar, Kiran (2022). Extracorporeal life support organization guidelines for fluid overload, acute kidney injury, and electrolyte management. ASAIO Journal, 68 (5), 611-618. doi: 10.1097/MAT.0000000000001702
2022
Journal Article
Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19: a randomized clinical trial
REMAP-CAP Writing Committee for the REMAP-CAP Investigators, Bradbury, Charlotte A., Lawler, Patrick R., Stanworth, Simon J., McVerry, Bryan J., McQuilten, Zoe, Higgins, Alisa M., Mouncey, Paul R., Al-Beidh, Farah, Rowan, Kathryn M., Berry, Lindsay R., Lorenzi, Elizabeth, Zarychanski, Ryan, Arabi, Yaseen M., Annane, Djillali, Beane, Abi, van Bentum-Puijk, Wilma, Bhimani, Zahra, Bihari, Shailesh, Bonten, Marc J. M., Brunkhorst, Frank M., Buzgau, Adrian, Buxton, Meredith, Carrier, Marc, Cheng, Allen C., Cove, Matthew, Detry, Michelle A., Estcourt, Lise J., Fitzgerald, Mark ... Gordon, Anthony C. (2022). Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19: a randomized clinical trial. JAMA: The Journal of the American Medical Association, 327 (13), 1247. doi: 10.1001/jama.2022.2910
2022
Journal Article
The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure
Shekar, Kiran and Ling, Ryan Ruiyang (2022). The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure. The Lancet Respiratory Medicine, 10 (6), 527-529. doi: 10.1016/S2213-2600(22)00051-0
2022
Journal Article
Population pharmacokinetics and dosing simulations of ceftriaxone in critically ill patients receiving extracorporeal membrane oxygenation (An ASAP ECMO Study)
Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Gilder, Eileen, Kim, Hyung-Sook, Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Fraser, John F., Shekar, Kiran, Roberts, Jason A. and ASAP ECMO Investigators (2022). Population pharmacokinetics and dosing simulations of ceftriaxone in critically ill patients receiving extracorporeal membrane oxygenation (An ASAP ECMO Study). Clinical Pharmacokinetics, 61 (6), 847-856. doi: 10.1007/s40262-021-01106-x
2022
Book Chapter
Challenges of antimicrobial therapy in ECMO patients
Cheng, Vesa, Abdul-Aziz, Mohd H. and Shekar, Kiran (2022). Challenges of antimicrobial therapy in ECMO patients. Extracorporeal membrane oxygenation: an interdisciplinary problem-based learning approach. (pp. 191-200) edited by Marc O. Maybauer. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780197521304.003.0018
2022
Book Chapter
Pharmacological considerations for analgesia and sedation of ECMO patients
Chew, Joshua, Cheng, Vesa and Shekar, Kiran (2022). Pharmacological considerations for analgesia and sedation of ECMO patients. Extracorporeal Membrane Oxygenation. (pp. 179-190) edited by Marc O. Maybauer. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780197521304.003.0017
2022
Journal Article
Colorectal surgery in critically unwell patients: a multidisciplinary approach
Subramaniam, Ashwin, Wengritzky, Robert, Skinner, Stewart and Shekar, Kiran (2022). Colorectal surgery in critically unwell patients: a multidisciplinary approach. Clinics in Colon and Rectal Surgery, 35 (03), 244-260. doi: 10.1055/s-0041-1740045
2022
Journal Article
Is intensive care unit mortality a valid survival outcome measure related to critical illness?
Laupland, Kevin B., Ramanan, Mahesh, Shekar, Kiran, Kirrane, Marianne, Clement, Pierre, Young, Patrick, Edwards, Felicity, Bushell, Rachel and Tabah, Alexis (2022). Is intensive care unit mortality a valid survival outcome measure related to critical illness?. Anaesthesia Critical Care and Pain Medicine, 41 (1) 100996, 100996. doi: 10.1016/j.accpm.2021.100996
2022
Journal Article
Frailty and mortality associations in patients with COVID-19: a systematic review and meta-analysis
Subramaniam, Ashwin, Shekar, Kiran, Afroz, Afsana, Ashwin, Sushma, Billah, Baki, Brown, Hamish, Kundi, Harun, Lim, Zheng Jie, Ponnapa Reddy, Mallikarjuna and Curtis, J Randall (2022). Frailty and mortality associations in patients with COVID-19: a systematic review and meta-analysis. Internal Medicine Journal, 52 (5), 724-739. doi: 10.1111/imj.15698
2022
Journal Article
Impact of unacceptable behaviour between healthcare workers on clinical performance and patient outcomes: a systematic review
Guo, Linda, Ryan, Benjamin, Leditschke, Isabel Anne, Haines, Kimberley J, Cook, Katrina, Eriksson, Lars, Olusanya, Olusegun, Selak, Tanya, Shekar, Kiran and Ramanan, Mahesh (2022). Impact of unacceptable behaviour between healthcare workers on clinical performance and patient outcomes: a systematic review. BMJ Quality and Safety, 31 (9) 013955, bmjqs-2021. doi: 10.1136/bmjqs-2021-013955
2022
Journal Article
Population pharmacokinetics of vancomycin in critically ill adult patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)
Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M., Kim, Hyung-Sook, Levkovich, Bianca J., Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Fraser, John F., Shekar, Kiran, Roberts, Jason A. and on behalf of ASAP ECMO Investigators (2022). Population pharmacokinetics of vancomycin in critically ill adult patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Antimicrobial Agents and Chemotherapy, 66 (1) AAC0137721, 1-10. doi: 10.1128/aac.01377-21
Supervision
Availability
- Professor Kiran Shekar is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Single Hand Used inTubaTing Laryngoscope Evaluation (SHUTTLE) Project
Associate Advisor
Other advisors: Emeritus Professor Jeffrey Lipman
Completed supervision
-
2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Associate Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Professor Jason Roberts
-
2019
Doctor Philosophy
Bioanalytical method development and validation to investigate cytochrome P450 mediated drug metabolism in patients receiving extracorporeal life support.
Associate Advisor
Other advisors: Emeritus Professor Maree Smith
Media
Enquiries
Contact Professor Kiran Shekar directly for media enquiries about their areas of expertise.
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: