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Professor Kiran Shekar
Professor

Kiran Shekar

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Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 350 peer-reviewed journal articles, 60 conference abstracts, 14 book chapters and has delivered over 150 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

332 works between 2008 and 2026

141 - 160 of 332 works

2022

Journal Article

Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers

Subramaniam, Ashwin, Reddy, Mallikarjuna, Kadam, Umesh, Zubarev, Alexander, Lim, Zheng, Anstey, Chris, Bihari, Shailesh, Haji, Jumana, Luo, Jinghang, Mitra, Saikat, Ramanathan, Kollengode, Rajamani, Arvind, Rubulotta, Francesca, Svensk, Erik and Shekar, Kiran (2022). Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers. Australian Critical Care, 35 (4), 415-423. doi: 10.1016/j.aucc.2021.06.015

Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers

2022

Journal Article

SARS-CoV-2 transmission risk to healthcare workers performing tracheostomies: a systematic review

Subramaniam, Ashwin, Lim, Zheng Jie, Ponnapa Reddy, Mallikarjuna, Mitchell, Hayden and Shekar, Kiran (2022). SARS-CoV-2 transmission risk to healthcare workers performing tracheostomies: a systematic review. ANZ Journal of Surgery, 92 (7-8), 1614-1625. doi: 10.1111/ans.17814

SARS-CoV-2 transmission risk to healthcare workers performing tracheostomies: a systematic review

2022

Journal Article

Reply Letter to the Editor Regarding the ELSO Interim Guidelines for Veno-Arterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients

Lorusso, Roberto, Bartlett, Robert H., Shekar, Kiran, MacLaren, Graeme, Schmidt, Matthieu, Pellegrino, Vincent, Meyns, Bart, Haft, Jonathan, Vercaemst, Leen, Pappalardo, Federico, Bermudez, Christian, Belohlavek, Jan, Hou, Xiaotong, Boeken, Udo, Castillo, Roberto, Donker, Dirk W., Abrams, Darryl, Ranucci, Marco, Hryniewicz, Kasia, Chavez, Ivan, Chen, Yih-Sharng, Salazar, Leonardo and Whitman, Glenn (2022). Reply Letter to the Editor Regarding the ELSO Interim Guidelines for Veno-Arterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients. ASAIO Journal, 68 (6), E111-E112. doi: 10.1097/MAT.0000000000001701

Reply Letter to the Editor Regarding the ELSO Interim Guidelines for Veno-Arterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients

2022

Journal Article

Development of a standardized assessment of simulation-based extracorporeal membrane oxygenation educational courses

Said, Ahmed S., Cooley, Elaine, Moore, Elizabeth A., Shekar, Kiran, Maul, Timothy M., Kollengode, Ramanathan and Zakhary, Bishoy (2022). Development of a standardized assessment of simulation-based extracorporeal membrane oxygenation educational courses. ATS Scholar, 3 (2), 242-257. doi: 10.34197/ats-scholar.2021-0068OC

Development of a standardized assessment of simulation-based extracorporeal membrane oxygenation educational courses

2022

Journal Article

Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Levkovich, Bianca J., Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Roberts, Jason A., Shekar, Kiran, Fraser, John F. and ASAP ECMO Investigators (2022). Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Anaesthesia Critical Care and Pain Medicine, 41 (3) 101080, 1-6. doi: 10.1016/j.accpm.2022.101080

Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

2022

Journal Article

Evolving outcomes of extracorporeal membrane oxygenation during the first 2 years of the COVID-19 pandemic: a systematic review and meta-analysis

Ling, Ryan Ruiyang, Ramanathan, Kollengode, Sim, Jackie Jia Lin, Wong, Suei Nee, Chen, Ying, Amin, Faizan, Fernando, Shannon M., Rochwerg, Bram, Fan, Eddy, Barbaro, Ryan P., MacLaren, Graeme, Shekar, Kiran and Brodie, Daniel (2022). Evolving outcomes of extracorporeal membrane oxygenation during the first 2 years of the COVID-19 pandemic: a systematic review and meta-analysis. Critical Care, 26 (1) 147, 1-13. doi: 10.1186/s13054-022-04011-2

Evolving outcomes of extracorporeal membrane oxygenation during the first 2 years of the COVID-19 pandemic: a systematic review and meta-analysis

2022

Journal Article

Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis

Li Bassi, Gianluigi, Gibbons, Kristen, Suen, Jacky Y., Dalton, Heidi J., White, Nicole, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Laffey, John G., Fan, Eddy, Fanning, Jonathon P., Panigada, Mauro, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Esperatti, Mariano, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Ogino, Mark, Pelosi, Paolo ... The COVID-19 Critical Care Consortium (2022). Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis. Critical Care, 26 (1) 141, 141. doi: 10.1186/s13054-022-03983-5

Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis

2022

Journal Article

Extracorporeal membrane oxygenation during pregnancy and peripartal. An international retrospective multicenter study

Malfertheiner, S. Fill, Brodie, D., Burrell, A., Taccone, F. S., Broman, L. M., Shekar, K., Agerstrand, C. L., Serra, A. L., Fraser, J. and Malfertheiner, M. V. (2022). Extracorporeal membrane oxygenation during pregnancy and peripartal. An international retrospective multicenter study. Perfusion, 38 (5), 1-7. doi: 10.1177/02676591221090668

Extracorporeal membrane oxygenation during pregnancy and peripartal. An international retrospective multicenter study

2022

Journal Article

Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study

Urner, Martin, Barnett, Adrian G., Bassi, Gianluigi Li, Brodie, Daniel, Dalton, Heidi J., Ferguson, Niall D., Heinsar, Silver, Hodgson, Carol L., Peek, Giles, Shekar, Kiran, Suen, Jacky Y., Fraser, John F., Fan, Eddy, COVID-19 Critical Care Consortium Investigators and Obonyo, Nchafatso (2022). Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study. BMJ, 377 e068723, e068723. doi: 10.1136/bmj-2021-068723

Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study

2022

Journal Article

Extracorporeal life support organization guidelines for fluid overload, acute kidney injury, and electrolyte management

Bridges, Brian C., Dhar, Archana, Ramanathan, Kollengode, Steflik, Heidi J., Schmidt, Matthieu and Shekar, Kiran (2022). Extracorporeal life support organization guidelines for fluid overload, acute kidney injury, and electrolyte management. ASAIO Journal, 68 (5), 611-618. doi: 10.1097/MAT.0000000000001702

Extracorporeal life support organization guidelines for fluid overload, acute kidney injury, and electrolyte management

2022

Journal Article

Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19: a randomized clinical trial

REMAP-CAP Writing Committee for the REMAP-CAP Investigators, Bradbury, Charlotte A., Lawler, Patrick R., Stanworth, Simon J., McVerry, Bryan J., McQuilten, Zoe, Higgins, Alisa M., Mouncey, Paul R., Al-Beidh, Farah, Rowan, Kathryn M., Berry, Lindsay R., Lorenzi, Elizabeth, Zarychanski, Ryan, Arabi, Yaseen M., Annane, Djillali, Beane, Abi, van Bentum-Puijk, Wilma, Bhimani, Zahra, Bihari, Shailesh, Bonten, Marc J. M., Brunkhorst, Frank M., Buzgau, Adrian, Buxton, Meredith, Carrier, Marc, Cheng, Allen C., Cove, Matthew, Detry, Michelle A., Estcourt, Lise J., Fitzgerald, Mark ... Gordon, Anthony C. (2022). Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19: a randomized clinical trial. JAMA: The Journal of the American Medical Association, 327 (13), 1247. doi: 10.1001/jama.2022.2910

Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19: a randomized clinical trial

2022

Journal Article

The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure

Shekar, Kiran and Ling, Ryan Ruiyang (2022). The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure. The Lancet Respiratory Medicine, 10 (6), 527-529. doi: 10.1016/S2213-2600(22)00051-0

The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure

2022

Journal Article

Population pharmacokinetics and dosing simulations of ceftriaxone in critically ill patients receiving extracorporeal membrane oxygenation (An ASAP ECMO Study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Gilder, Eileen, Kim, Hyung-Sook, Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Fraser, John F., Shekar, Kiran, Roberts, Jason A. and ASAP ECMO Investigators (2022). Population pharmacokinetics and dosing simulations of ceftriaxone in critically ill patients receiving extracorporeal membrane oxygenation (An ASAP ECMO Study). Clinical Pharmacokinetics, 61 (6), 847-856. doi: 10.1007/s40262-021-01106-x

Population pharmacokinetics and dosing simulations of ceftriaxone in critically ill patients receiving extracorporeal membrane oxygenation (An ASAP ECMO Study)

2022

Book Chapter

Challenges of antimicrobial therapy in ECMO patients

Cheng, Vesa, Abdul-Aziz, Mohd H. and Shekar, Kiran (2022). Challenges of antimicrobial therapy in ECMO patients. Extracorporeal membrane oxygenation: an interdisciplinary problem-based learning approach. (pp. 191-200) edited by Marc O. Maybauer. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780197521304.003.0018

Challenges of antimicrobial therapy in ECMO patients

2022

Book Chapter

Pharmacological considerations for analgesia and sedation of ECMO patients

Chew, Joshua, Cheng, Vesa and Shekar, Kiran (2022). Pharmacological considerations for analgesia and sedation of ECMO patients. Extracorporeal Membrane Oxygenation. (pp. 179-190) edited by Marc O. Maybauer. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780197521304.003.0017

Pharmacological considerations for analgesia and sedation of ECMO patients

2022

Journal Article

Colorectal surgery in critically unwell patients: a multidisciplinary approach

Subramaniam, Ashwin, Wengritzky, Robert, Skinner, Stewart and Shekar, Kiran (2022). Colorectal surgery in critically unwell patients: a multidisciplinary approach. Clinics in Colon and Rectal Surgery, 35 (03), 244-260. doi: 10.1055/s-0041-1740045

Colorectal surgery in critically unwell patients: a multidisciplinary approach

2022

Journal Article

Is intensive care unit mortality a valid survival outcome measure related to critical illness?

Laupland, Kevin B., Ramanan, Mahesh, Shekar, Kiran, Kirrane, Marianne, Clement, Pierre, Young, Patrick, Edwards, Felicity, Bushell, Rachel and Tabah, Alexis (2022). Is intensive care unit mortality a valid survival outcome measure related to critical illness?. Anaesthesia Critical Care and Pain Medicine, 41 (1) 100996, 100996. doi: 10.1016/j.accpm.2021.100996

Is intensive care unit mortality a valid survival outcome measure related to critical illness?

2022

Journal Article

Frailty and mortality associations in patients with COVID-19: a systematic review and meta-analysis

Subramaniam, Ashwin, Shekar, Kiran, Afroz, Afsana, Ashwin, Sushma, Billah, Baki, Brown, Hamish, Kundi, Harun, Lim, Zheng Jie, Ponnapa Reddy, Mallikarjuna and Curtis, J Randall (2022). Frailty and mortality associations in patients with COVID-19: a systematic review and meta-analysis. Internal Medicine Journal, 52 (5), 724-739. doi: 10.1111/imj.15698

Frailty and mortality associations in patients with COVID-19: a systematic review and meta-analysis

2022

Journal Article

Impact of unacceptable behaviour between healthcare workers on clinical performance and patient outcomes: a systematic review

Guo, Linda, Ryan, Benjamin, Leditschke, Isabel Anne, Haines, Kimberley J, Cook, Katrina, Eriksson, Lars, Olusanya, Olusegun, Selak, Tanya, Shekar, Kiran and Ramanan, Mahesh (2022). Impact of unacceptable behaviour between healthcare workers on clinical performance and patient outcomes: a systematic review. BMJ Quality and Safety, 31 (9) 013955, bmjqs-2021. doi: 10.1136/bmjqs-2021-013955

Impact of unacceptable behaviour between healthcare workers on clinical performance and patient outcomes: a systematic review

2022

Journal Article

Population pharmacokinetics of vancomycin in critically ill adult patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M., Kim, Hyung-Sook, Levkovich, Bianca J., Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Fraser, John F., Shekar, Kiran, Roberts, Jason A. and on behalf of ASAP ECMO Investigators (2022). Population pharmacokinetics of vancomycin in critically ill adult patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Antimicrobial Agents and Chemotherapy, 66 (1) AAC0137721, 1-10. doi: 10.1128/aac.01377-21

Population pharmacokinetics of vancomycin in critically ill adult patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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