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Professor Kiran Shekar
Professor

Kiran Shekar

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Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 350 peer-reviewed journal articles, 60 conference abstracts, 14 book chapters and has delivered over 150 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

332 works between 2008 and 2026

161 - 180 of 332 works

2022

Journal Article

Characteristics and outcomes of patients with frailty admitted to ICU with Coronavirus disease 2019: An individual patient data meta-analysis

Subramaniam, Ashwin, Anstey, Christopher, Curtis, J Randall, Ashwin, Sushma, Ponnapa Reddy, Mallikarjuna, Aliberti, Márlon Juliano Romero, Avelino-Silva, Thiago Junqueira, Welch, Carly, Koduri, Gouri, Prowle, John R, Wan, Yize I, Laurent, Michaël R, Marengoni, Alessandra, Lim, Jun Pei, Pilcher, David and Shekar, Kiran (2022). Characteristics and outcomes of patients with frailty admitted to ICU with Coronavirus disease 2019: An individual patient data meta-analysis. Critical Care Explorations, 4 (1) e0616, e0616. doi: 10.1097/CCE.0000000000000616

Characteristics and outcomes of patients with frailty admitted to ICU with Coronavirus disease 2019: An individual patient data meta-analysis

2022

Journal Article

Hyperoxia on venoarterial extracorporeal membrane oxygenation: a modifiable risk?

Joyce, Christopher J., Anderson, Cameron and Shekar, Kiran (2022). Hyperoxia on venoarterial extracorporeal membrane oxygenation: a modifiable risk?. Critical Care Medicine, 50 (1), e99-e100. doi: 10.1097/CCM.0000000000005252

Hyperoxia on venoarterial extracorporeal membrane oxygenation: a modifiable risk?

2021

Journal Article

Erratum: A systematic review of the incidence and outcomes of in-hospital cardiac arrests in patients with coronavirus disease 2019 (Critical Care Medicine (2019) 49 (901-911) DOI: 10.1097/CCM.0000000000004950)

Lim, Zheng Jie, Reddy, Mallikarjuna Ponnapa, Randall Curtis, J., Afroz, Afsana, Billah, Baki, Hayek, Salim S., Leaf, David E., Miles, Jeremy A., Yuriditsky, Eugene, Jones, Daryl, Shekar, Kiran and Subramaniam, Ashwin (2021). Erratum: A systematic review of the incidence and outcomes of in-hospital cardiac arrests in patients with coronavirus disease 2019 (Critical Care Medicine (2019) 49 (901-911) DOI: 10.1097/CCM.0000000000004950). Critical Care Medicine, 49 (12). doi: 10.1097/CCM.0000000000005384

Erratum: A systematic review of the incidence and outcomes of in-hospital cardiac arrests in patients with coronavirus disease 2019 (Critical Care Medicine (2019) 49 (901-911) DOI: 10.1097/CCM.0000000000004950)

2021

Journal Article

Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis

Ramanathan, Kollengode, Shekar, Kiran, Ling, Ryan Ruiyang, Barbaro, Ryan P., Wong, Suei Nee, Tan, Chuen Seng, Rochwerg, Bram, Fernando, Shannon M., Takeda, Shinhiro, MacLaren, Graeme, Fan, Eddy and Brodie, Daniel (2021). Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis. Critical Care, 25 (1) 211, 211. doi: 10.1186/s13054-021-03634-1

Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis

2021

Journal Article

Population pharmacokinetics of cefepime in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Jakob, Stephan M., Levkovich, Bianca J., Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Roberts, Jason A., Shekar, Kiran, Fraser, John F. and on behalf ofASAP ECMO Investigators (2021). Population pharmacokinetics of cefepime in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). International Journal of Antimicrobial Agents, 58 (6) 106466, 1-8. doi: 10.1016/j.ijantimicag.2021.106466

Population pharmacokinetics of cefepime in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

2021

Journal Article

Erratum: Trends in 28-Day mortality of critical care patients with coronavirus disease 2019 in the United Kingdom: A National Cohort Study, March 2020 to January 2021 (Critical Care Medicine (2021) 49 (1895-1900) DOI: 10.1097/CCM.0000000000005184)

Lim, Zheng Jie, Reddy, Mallikarjuna Ponnapa, Randall Curtis, J., Afroz, Afsana, Billah, Baki, Hayek, Salim S., Leaf, David E., Miles, Jeremy A., Yuriditsky, Eugene, Jones, Daryl, Shekar, Kiran and Subramaniam, Ashwin (2021). Erratum: Trends in 28-Day mortality of critical care patients with coronavirus disease 2019 in the United Kingdom: A National Cohort Study, March 2020 to January 2021 (Critical Care Medicine (2021) 49 (1895-1900) DOI: 10.1097/CCM.0000000000005184). Critical Care Medicine, 49 (12). doi: 10.1097/CCM.0000000000005385

Erratum: Trends in 28-Day mortality of critical care patients with coronavirus disease 2019 in the United Kingdom: A National Cohort Study, March 2020 to January 2021 (Critical Care Medicine (2021) 49 (1895-1900) DOI: 10.1097/CCM.0000000000005184)

2021

Journal Article

Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis

Poon, Wynne Hsing, Ramanathan, Kollengode, Ling, Ryan Ruiyang, Yang, Isabelle Xiaorui, Tan, Chuen Seng, Schmidt, Matthieu and Shekar, Kiran (2021). Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis. Critical Care, 25 (1) 292, 292. doi: 10.1186/s13054-021-03723-1

Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis

2021

Journal Article

Reconciling the obesity paradox: obese patients suffer the highest critical illness associated mortality rates

Laupland, Kevin B., Edwards, Felicity, Ramanan, Mahesh, Shekar, Kiran and Tabah, Alexis (2021). Reconciling the obesity paradox: obese patients suffer the highest critical illness associated mortality rates. Journal of Critical Care, 66, 75-77. doi: 10.1016/j.jcrc.2021.08.005

Reconciling the obesity paradox: obese patients suffer the highest critical illness associated mortality rates

2021

Journal Article

Non-home discharge after cardiac surgery in Australia and New Zealand: a cross-sectional study

Ramanan, Mahesh, Kumar, Aashish, Anstey, Chris and Shekar, Kiran (2021). Non-home discharge after cardiac surgery in Australia and New Zealand: a cross-sectional study. BMJ Open, 11 (12) e049187, e049187. doi: 10.1136/bmjopen-2021-049187

Non-home discharge after cardiac surgery in Australia and New Zealand: a cross-sectional study

2021

Journal Article

The association of oxygenation, carbon dioxide removal, and mechanical ventilation practices on survival during venoarterial extracorporeal membrane oxygenation

Justus, Angelo, Burrell, Aidan, Anstey, Chris, Cornmell, George, Brodie, Daniel and Shekar, Kiran (2021). The association of oxygenation, carbon dioxide removal, and mechanical ventilation practices on survival during venoarterial extracorporeal membrane oxygenation. Frontiers in Medicine, 8 756280, 756280. doi: 10.3389/fmed.2021.756280

The association of oxygenation, carbon dioxide removal, and mechanical ventilation practices on survival during venoarterial extracorporeal membrane oxygenation

2021

Journal Article

What determines the arterial partial pressure of carbon dioxide on venovenous extracorporeal membrane oxygenation?

Joyce, Christopher J., Udy, Andrew, Weeden, Mark, Shekar, Kiran and Cook, David A. (2021). What determines the arterial partial pressure of carbon dioxide on venovenous extracorporeal membrane oxygenation?. ASAIO Journal, 68 (8), 1093-1103. doi: 10.1097/mat.0000000000001604

What determines the arterial partial pressure of carbon dioxide on venovenous extracorporeal membrane oxygenation?

2021

Journal Article

Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M, Kim, Hyung-Sook, Levkovich, Bianca J., Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Zacharias, David, Fraser, John F., Shekar, Kiran, Roberts, Jason A. and on behalf of ASAP ECMO Investigators (2021). Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Antimicrobial Agents and Chemotherapy, 65 (11) e01438-21, 1-11. doi: 10.1128/aac.01438-21

Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

2021

Journal Article

Systematic review and meta-analysis of the characteristics and outcomes of readmitted COVID-19 survivors

Subramaniam, Ashwin, Lim, Zheng Jie, Ponnapa Reddy, Mallikarjuna and Shekar, Kiran (2021). Systematic review and meta-analysis of the characteristics and outcomes of readmitted COVID-19 survivors. Internal Medicine Journal, 51 (11), 1773-1780. doi: 10.1111/imj.15350

Systematic review and meta-analysis of the characteristics and outcomes of readmitted COVID-19 survivors

2021

Journal Article

Feasibility of non-invasive nitric oxide gas inhalation to prevent endotracheal intubation in patients with acute hypoxemic respiratory failure: a single-centre experience

Shekar, Kiran, Varkey, Sneha, Cornmell, George, Parsons, Leanne, Tol, Maneesha, Siuba, Matthew and Ramanan, Mahesh (2021). Feasibility of non-invasive nitric oxide gas inhalation to prevent endotracheal intubation in patients with acute hypoxemic respiratory failure: a single-centre experience. Nitric Oxide, 116, 35-37. doi: 10.1016/j.niox.2021.08.005

Feasibility of non-invasive nitric oxide gas inhalation to prevent endotracheal intubation in patients with acute hypoxemic respiratory failure: a single-centre experience

2021

Journal Article

Correction to: Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis

Ramanathan, Kollengode, Shekar, Kiran, Ling, Ryan Ruiyang, Barbaro, Ryan P, Wong, Suei Nee, Tan, Chuen Seng, Rochwerg, Bram, Fernando, Shannon M, Takeda, Shinhiro, MacLaren, Graeme, Fan, Eddy and Brodie, Daniel (2021). Correction to: Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis. Critical Care, 25 (1) 375, 375. doi: 10.1186/s13054-021-03714-2

Correction to: Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis

2021

Journal Article

Fluid resuscitation after cardiac surgery in the intensive care unit: a bi-national survey of clinician practice. (The FRACS-ICU clinician survey)

Ramanan, Mahesh, Roberts, Shaun, Adrian McCullough, James, Naidoo, Rishendran, Rapchuk, Ivan, Matebele, Mbakise, Tabah, Alexis, Kruger, Peter, Smith, Julian and Shekar, Kiran (2021). Fluid resuscitation after cardiac surgery in the intensive care unit: a bi-national survey of clinician practice. (The FRACS-ICU clinician survey). Annals of Cardiac Anaesthesia, 24 (4), 441-446. doi: 10.4103/aca.ACA_190_20

Fluid resuscitation after cardiac surgery in the intensive care unit: a bi-national survey of clinician practice. (The FRACS-ICU clinician survey)

2021

Journal Article

Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications

Abrams, Darryl, MacLaren, Graeme, Lorusso, Roberto, Price, Susanna, Yannopoulos, Demetris, Vercaemst, Leen, Bělohlávek, Jan, Taccone, Fabio S., Aissaoui, Nadia, Shekar, Kiran, Garan, A. Reshad, Uriel, Nir, Tonna, Joseph E., Jung, Jae Seung, Takeda, Koji, Chen, Yih-Sharng, Slutsky, Arthur S., Combes, Alain and Brodie, Daniel (2021). Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications. Intensive Care Medicine, 48 (1), 1-15. doi: 10.1007/s00134-021-06514-y

Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications

2021

Journal Article

Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial

Arabi, Yaseen M., Gordon, Anthony C., Derde, Lennie P. G., Nichol, Alistair D., Murthy, Srinivas, Beidh, Farah Al, Annane, Djillali, Swaidan, Lolowa Al, Beane, Abi, Beasley, Richard, Berry, Lindsay R., Bhimani, Zahra, Bonten, Marc J. M., Bradbury, Charlotte A., Brunkhorst, Frank M., Buxton, Meredith, Buzgau, Adrian, Cheng, Allen, De Jong, Menno, Detry, Michelle A., Duffy, Eamon J., Estcourt, Lise J., Fitzgerald, Mark, Fowler, Rob, Girard, Timothy D., Goligher, Ewan C., Goossens, Herman, Haniffa, Rashan, Higgins, Alisa M. ... on behalf of the REMAP-CAP Investigators (2021). Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial. Intensive Care Medicine, 47 (8), 867-886. doi: 10.1007/s00134-021-06448-5

Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial

2021

Journal Article

ELSO interim guidelines for venoarterial extracorporeal membrane oxygenation in adult cardiac patients

Lorusso, Roberto, Shekar, Kiran, MacLaren, Graeme, Schmidt, Matthieu, Pellegrino, Vincent, Meyns, Bart, Haft, Jonathan, Vercaemst, Leen, Pappalardo, Federico, Bermudez, Christian, Belohlavek, Jan, Hou, Xiaotong, Boeken, Udo, Castillo, Roberto, Donker, Dirk W, Abrams, Darryl, Ranucci, Marco, Hryniewicz, Kasia, Chavez, Ivan, Chen, Yih-Sharng, Salazar, Leonardo and Whitman, Glenn (2021). ELSO interim guidelines for venoarterial extracorporeal membrane oxygenation in adult cardiac patients. ASAIO Journal, 67 (8), 827-844. doi: 10.1097/MAT.0000000000001510

ELSO interim guidelines for venoarterial extracorporeal membrane oxygenation in adult cardiac patients

2021

Journal Article

Assessing need for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest using Power BI for data visualisation

Ramanan, Mahesh, Gill, Denzil, Doan, Tan, Bosley, Emma, Rashford, Stephen, Dennis, Mark and Shekar, Kiran (2021). Assessing need for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest using Power BI for data visualisation. Emergency Medicine Australasia, 33 (4), 685-690. doi: 10.1111/1742-6723.13704

Assessing need for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest using Power BI for data visualisation

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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