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Professor Kiran Shekar
Professor

Kiran Shekar

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Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 350 peer-reviewed journal articles, 60 conference abstracts, 14 book chapters and has delivered over 150 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

332 works between 2008 and 2026

221 - 240 of 332 works

2020

Journal Article

Position paper on global extracorporeal membrane oxygenation education and educational agenda for the future: a statement from the Extracorporeal Life Support Organization ECMOed Taskforce

Zakhary, Bishoy, Shekar, Kiran, Diaz, Rodrigo, Badulak, Jenelle, Johnston, Lindsay, Roeleveld, Peter Paul, Alinier, Guillaume, Lai, Peter Chi Keung, Ramanathan, Kollengode, Moore, Elizabeth, Hassan, Ibrahim, Agerstrand, Cara, Ngai, Wallace Chun-Wai, Salazar, Leonardo, Raman, Lakshmi, Bembea, Melania M., Davidson, Mark, Gomez-Gutierrez, Rene D., Mateo-Sidrón, Jose Alfonso Rubio, Kukutschka, Jeannie, Antonini, Marta V., Dickstein, Marc L., Schmidt, Matthieu, Abrams, Darryl and Ogino, Mark T. (2020). Position paper on global extracorporeal membrane oxygenation education and educational agenda for the future: a statement from the Extracorporeal Life Support Organization ECMOed Taskforce. Critical Care Medicine, 48 (3), 406-414. doi: 10.1097/CCM.0000000000004158

Position paper on global extracorporeal membrane oxygenation education and educational agenda for the future: a statement from the Extracorporeal Life Support Organization ECMOed Taskforce

2020

Journal Article

Mechanical ventilation for acute respiratory distress syndrome during extracorporeal life support research and practice

Abrams, Darryl, Schmidt, Matthieu, Pham, Tái, Beitler, Jeremy R., Fan, Eddy, Goligher, Ewan C., McNamee, James J., Patroniti, Nicoló, Wilcox, M. Elizabeth, Combes, Alain, Ferguson, Niall D., McAuley, Danny F., Pesenti, Antonio, Quintel, Michael, Fraser, John, Hodgson, Carol L., Hough, Catherine L., Mercat, Alain, Mueller, Thomas, Pellegrino, Vin, Ranieri, V. Marco, Rowan, Kathy, Shekar, Kiran, Brochard, Laurent and Brodie, Daniel (2020). Mechanical ventilation for acute respiratory distress syndrome during extracorporeal life support research and practice. American Journal of Respiratory and Critical Care Medicine, 201 (5), 514-525. doi: 10.1164/rccm.201907-1283CI

Mechanical ventilation for acute respiratory distress syndrome during extracorporeal life support research and practice

2020

Journal Article

Assessment of the Clinical Pulmonary Infection Scores for prediction of ventilator associated pneumonia in patients with out of hospital cardiac arrest

Manchal, Naveen, Siriwardena, Maithri, Hay, Karen, Shekar, Kiran and McNamara, John F. (2020). Assessment of the Clinical Pulmonary Infection Scores for prediction of ventilator associated pneumonia in patients with out of hospital cardiac arrest. Infection, Disease and Health, 26 (1), 48-54. doi: 10.1016/j.idh.2020.09.001

Assessment of the Clinical Pulmonary Infection Scores for prediction of ventilator associated pneumonia in patients with out of hospital cardiac arrest

2020

Journal Article

Clinical care of pregnant and postpartum women with COVID-19: living recommendations from the National COVID-19 Clinical Evidence Taskforce

Vogel, Joshua P., Tendal, Britta, Giles, Michelle, Whitehead, Clare, Burton, Wendy, Chakraborty, Samantha, Cheyne, Saskia, Downton, Teena, Fraile Navarro, David, Gleeson, Glenda, Gordon, Adrienne, Hunt, Jenny, Kitschke, Jackie, McDonald, Steven, McDonnell, Nolan, Middleton, Philippa, Millard, Tanya, Murano, Melissa, Oats, Jeremy, Tate, Rhiannon, White, Heath, Elliott, Julian, Roach, Vijay, Homer, Caroline S.E., McGowan, Sharon, Ballenden, Nicola, Barrett, Terri-Lee, Beavis, Vanessa, Saunders, James Beckford ... National COVID-19 Clinical Evidence Taskforce (2020). Clinical care of pregnant and postpartum women with COVID-19: living recommendations from the National COVID-19 Clinical Evidence Taskforce. Australian and New Zealand Journal of Obstetrics and Gynaecology, 60 (6) ajo.13270, 840-851. doi: 10.1111/ajo.13270

Clinical care of pregnant and postpartum women with COVID-19: living recommendations from the National COVID-19 Clinical Evidence Taskforce

2019

Journal Article

Risk factors for mortality in patients undergoing cardiothoracic surgery for infective endocarditis

Kumar, Aashish, Anstey, Chris, Tesar, Peter and Shekar, Kiran (2019). Risk factors for mortality in patients undergoing cardiothoracic surgery for infective endocarditis. Annals of Thoracic Surgery, 108 (4), 1101-1106. doi: 10.1016/j.athoracsur.2019.05.029

Risk factors for mortality in patients undergoing cardiothoracic surgery for infective endocarditis

2019

Journal Article

Antimicrobial therapy during ECMO – customised dosing with therapeutic drug monitoring: the way to go?

Abdul-Aziz, Mohd H., Shekar, Kiran and Roberts, Jason A. (2019). Antimicrobial therapy during ECMO – customised dosing with therapeutic drug monitoring: the way to go?. Anaesthesia Critical Care and Pain Medicine, 38 (5), 451-453. doi: 10.1016/j.accpm.2019.07.005

Antimicrobial therapy during ECMO – customised dosing with therapeutic drug monitoring: the way to go?

2019

Journal Article

Should Patients With Acute Respiratory Distress Syndrome on Venovenous Extracorporeal Membrane Oxygenation Have Ventilatory Support Reduced to the Lowest Tolerable Settings? No

Shekar, Kiran and Brodie, Daniel (2019). Should Patients With Acute Respiratory Distress Syndrome on Venovenous Extracorporeal Membrane Oxygenation Have Ventilatory Support Reduced to the Lowest Tolerable Settings? No. Critical Care Medicine, 47 (8), 1147-1149. doi: 10.1097/CCM.0000000000003865

Should Patients With Acute Respiratory Distress Syndrome on Venovenous Extracorporeal Membrane Oxygenation Have Ventilatory Support Reduced to the Lowest Tolerable Settings? No

2019

Journal Article

ECMO for immunosuppressed patients with acute respiratory distress syndrome: drawing a line in the sand

Schmidt, Matthieu, Combes, Alain and Shekar, Kiran (2019). ECMO for immunosuppressed patients with acute respiratory distress syndrome: drawing a line in the sand. Intensive Care Medicine, 45 (8), 1140-1142. doi: 10.1007/s00134-019-05632-y

ECMO for immunosuppressed patients with acute respiratory distress syndrome: drawing a line in the sand

2019

Journal Article

Integrating mechanical ventilation and extracorporeal membrane oxygenation in severe acute respiratory distress syndrome

Shekar, Kiran and Schmidt, Matthieu (2019). Integrating mechanical ventilation and extracorporeal membrane oxygenation in severe acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine, 200 (2), 265-266. doi: 10.1164/rccm.201903-0594LE

Integrating mechanical ventilation and extracorporeal membrane oxygenation in severe acute respiratory distress syndrome

2019

Journal Article

Awake extracorporeal membrane oxygenation in immunosuppressed patients with severe respiratory failure-a stretch too far?

Shekar, Kiran, Abrams, Darryl and Schmidt, Matthieu (2019). Awake extracorporeal membrane oxygenation in immunosuppressed patients with severe respiratory failure-a stretch too far?. Journal of Thoracic Disease, 11 (7), 2656-2659. doi: 10.21037/jtd.2019.05.58

Awake extracorporeal membrane oxygenation in immunosuppressed patients with severe respiratory failure-a stretch too far?

2019

Journal Article

Steps to enhance safety of tracheostomy on ECMO

Grewal, Jatinder, Sutt, Anna-Liisa, Shekar, Kiran and Fraser, John F. (2019). Steps to enhance safety of tracheostomy on ECMO. Journal of Intensive Care Medicine, 2019, 088506661985107-2. doi: 10.1177/0885066619851074

Steps to enhance safety of tracheostomy on ECMO

2019

Journal Article

Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy

Adiraju, Santosh Kumar Sreevatsav, Shekar, Kiran, Tesar, Peter, Naidoo, Rishendran, Rapchuk, Ivan, Belz, Stephen, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2019). Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy. Methods and Protocols, 2 (2) 38, 38-12. doi: 10.3390/mps2020038

Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy

2019

Journal Article

Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation

Shekar, Kiran, Grewal, Jatinder, Sutt, Anna Lisa and Fraser, John (2019). Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation. ASAIO journal (American Society for Artificial Internal Organs : 1992), 65 (4), e44-e45. doi: 10.1097/MAT.0000000000000969

Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation

2019

Journal Article

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock

Passmore, Margaret R., Obonyo, Nchafatso G., Byrne, Liam, Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Fung, Yoke L., Spanevello, Michelle M., Fauzi, Mohd H., Pedersen, Sanne E., Simonova, Gabriela, Anstey, Chris M., Shekar, Kiran, Tung, John-Paul, Maitland, Kathryn and Fraser, John F. (2019). Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock. Thrombosis Research, 176, 39-45. doi: 10.1016/j.thromres.2019.02.015

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock

2019

Journal Article

Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience

Grewal, Jatinder, Sutt, Anna-Liisa, Cornmell, George, Shekar, Kiran and Fraser, John (2019). Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience. Journal of Intensive Care Medicine, 35 (11), 1153-1161. doi: 10.1177/0885066619837939

Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience

2019

Journal Article

Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients

Cheng, Vesa, Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2019). Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients. Expert Opinion on Drug Metabolism & Toxicology, 15 (2), 103-112. doi: 10.1080/17425255.2019.1563596

Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients

2019

Journal Article

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

Obonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

2018

Journal Article

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

Passmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

2018

Conference Publication

Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation. American Heart Association's 2018 Scientific Sessions, Chicago, IL United States, 10-12 November 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1161/circ.138.suppl_1.17116

Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation

2018

Journal Article

Oscillating between prone ventilation and ECMO?

Lavana, Jayshree and Shekar, Kiran (2018). Oscillating between prone ventilation and ECMO?. Journal of Thoracic Disease, 10 (S33), S4144-S4146. doi: 10.21037/jtd.2018.10.71

Oscillating between prone ventilation and ECMO?

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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