Overview
Background
Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 350 peer-reviewed journal articles, 60 conference abstracts, 14 book chapters and has delivered over 150 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.
Availability
- Professor Kiran Shekar is:
- Available for supervision
- Media expert
Research interests
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Extracorporeal membrane oxygenation
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Respiratory failure and minimising the burden of invasive mechanical ventilation
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PK/PD on Extracorporeal membrane oxygenation support
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Cardiogenic Shock and Mechanical Circulatory Support
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Microcirculation on temporary Mechanical Circulatory Support
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Building a budget intensive care unit to improve intensive care access in resource poor countries
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Standardising ECMO education to bridge the variability in global ECMO outcomes
Works
Search Professor Kiran Shekar’s works on UQ eSpace
2020
Journal Article
Will not breathing on extracorporeal membrane oxygenation help one survive acute respiratory distress syndrome?*
Shekar, Kiran, McAuley, Daniel F. and Brodie, Daniel (2020). Will not breathing on extracorporeal membrane oxygenation help one survive acute respiratory distress syndrome?*. Critical Care Medicine, 48 (12), 1901-1904. doi: 10.1097/ccm.0000000000004647
2020
Journal Article
Extracorporeal life support for adults with acute respiratory distress syndrome
Combes, Alain, Schmidt, Matthieu, Hodgson, Carol L., Fan, Eddy, Ferguson, Niall D., Fraser, John F., Jaber, Samir, Pesenti, Antonio, Ranieri, Marco, Rowan, Kathryn, Shekar, Kiran, Slutsky, Arthur S. and Brodie, Daniel (2020). Extracorporeal life support for adults with acute respiratory distress syndrome. Intensive Care Medicine, 46 (12), 2464-2476. doi: 10.1007/s00134-020-06290-1
2020
Journal Article
Protocol-driven daily optimisation of venovenous extracorporeal membrane oxygenation blood flows: an alternate paradigm?
Shekar, Kiran, Buscher, Hergen and Brodie, Daniel (2020). Protocol-driven daily optimisation of venovenous extracorporeal membrane oxygenation blood flows: an alternate paradigm?. Journal of Thoracic Disease, 12 (11), 6854-6860. doi: 10.21037/jtd-20-1515
2020
Journal Article
Incidence and outcome of out-of-hospital cardiac arrests in the COVID-19 era: A systematic review and meta-analysis
Lim, Zheng Jie, Ponnapa Reddy, Mallikarjuna, Afroz, Afsana, Billah, Baki, Shekar, Kiran and Subramaniam, Ashwin (2020). Incidence and outcome of out-of-hospital cardiac arrests in the COVID-19 era: A systematic review and meta-analysis. Resuscitation, 157, 248-258. doi: 10.1016/j.resuscitation.2020.10.025
2020
Journal Article
2020 EACTS/ELSO/STS/AATS expert consensus on post-cardiotomy extracorporeal life support in adult patients
Lorusso, Roberto, Whitman, Glenn, Milojevic, Milan, Raffa, Giuseppe, McMullan, David M., Boeken, Udo, Haft, Jonathan, Bermudez, Christian A, Shah, Ashish S, D'Alessandro, David A, for the ESC Scientific Document Group and Shekar, Kiran (2020). 2020 EACTS/ELSO/STS/AATS expert consensus on post-cardiotomy extracorporeal life support in adult patients. European Journal of Cardio-Thoracic Surgery, 59 (1), 1-42. doi: 10.1093/ejcts/ezaa283
2020
Journal Article
Small lessons during COVID having a large impact on surgical management
McGrath, N. and Shekar, K. (2020). Small lessons during COVID having a large impact on surgical management. British Journal of Oral and Maxillofacial Surgery, 58 (8), 1059-1060. doi: 10.1016/j.bjoms.2020.07.008
2020
Journal Article
Personal protective equipment preparedness in Asia-Pacific intensive care units during the coronavirus disease 2019 pandemic: a multinational survey
Rajamani, Arvind, Subramaniam, Ashwin, Shekar, Kiran, Haji, Jumana, Luo, Jinghang, Bihari, Shailesh, Wong, Wai Tat, Gullapalli, Navya, Renner, Markus, Alcancia, Claudia Maria, Ramanathan, Kollengode and SPARTAN Collaborative - Small Projects, Audits, Research Trials – Australia/New Zealand (2020). Personal protective equipment preparedness in Asia-Pacific intensive care units during the coronavirus disease 2019 pandemic: a multinational survey. Australian Critical Care, 34 (2), 135-141. doi: 10.1016/j.aucc.2020.09.006
2020
Journal Article
Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry
Barbaro, Ryan P., MacLaren, Graeme, Boonstra, Philip S., Iwashyna, Theodore J., Slutsky, Arthur S., Fan, Eddy, Bartlett, Robert H., Tonna, Joseph E., Hyslop, Robert, Fanning, Jeffrey J., Rycus, Peter T., Hyer, Steve J., Anders, Marc M., Agerstrand, Cara L., Hryniewicz, Katarzyna, Diaz, Rodrigo, Lorusso, Roberto, Combes, Alain, Brodie, Daniel, Extracorporeal Life Support Organization, Shekar, Kiran and Fraser, John (2020). Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry. Lancet , 396 (10257), 1071-1078. doi: 10.1016/S0140-6736(20)32008-0
2020
Journal Article
Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation
Marella, Prashanti, Roberts, Jason, Hay, Karen and Shekar, Kiran (2020). Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation. Antimicrobial Agents and Chemotherapy, 64 (9) e01179-20. doi: 10.1128/aac.01179-20
2020
Journal Article
ECMO for severe ARDS associated with COVID-19: now we know we can, but should we?
Shekar, Kiran, Slutsky, Arthur S. and Brodie, Daniel (2020). ECMO for severe ARDS associated with COVID-19: now we know we can, but should we?. The Lancet. Respiratory Medicine, 8 (11), 1066-1068. doi: 10.1016/s2213-2600(20)30357-x
2020
Journal Article
Venoarterial extracorporeal membrane oxygenation: if you cannot measure it, you cannot improve it
Shekar, Kiran, Donker, Dirk W. and Brodie, Daniel (2020). Venoarterial extracorporeal membrane oxygenation: if you cannot measure it, you cannot improve it. Anesthesiology, 133 (4), 708-710. doi: 10.1097/aln.0000000000003487
2020
Journal Article
Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep
Millar, Jonathan E., Bartnikowski, Nicole, Passmore, Margaret R., Obonyo, Nchafatso G, Malfertheiner, Maximillian V., von Bahr, Viktor, Redd, Meredith A., See Hoe, Louise, Ki, Katrina K., Pedersen, Sanne, Boyle, Andrew J., Baillie, J Kenneth, Shekar, Kiran, Palpant, Nathan, Suen, Jacky Y., Matthay, Michael A., McAuley, Daniel F., Fraser, John F. and Combining Extracorporeal Life Support and Cell Therapy in Critical Illness (CELTIC) investigators (2020). Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep. American Journal of Respiratory and Critical Care Medicine, 202 (3) rccm.201911-2143OC, 383-392. doi: 10.1164/rccm.201911-2143oc
2020
Journal Article
Provision of ECPR during COVID-19: evidence, equity, and ethical dilemmas
Worku, Elliott, Gill, Denzil, Brodie, Daniel, Lorusso, Roberto, Combes, Alain and Shekar, Kiran (2020). Provision of ECPR during COVID-19: evidence, equity, and ethical dilemmas. Critical Care, 24 (1) 462, 462. doi: 10.1186/s13054-020-03172-2
2020
Journal Article
Extubate before VV ECMO decannulation or decannulate while remaining on the ventilator? The EuroELSO 2019 Weaning Survey
Swol, Justyna, Shekar, Kiran, Protti, Alessandro, Tukacs, Monika, Broman, Lars Mikael, Barrett, Nicholas A., Mueller, Thomas, Peek, Giles J. and Buscher, Hergen (2020). Extubate before VV ECMO decannulation or decannulate while remaining on the ventilator? The EuroELSO 2019 Weaning Survey. ASAIO Journal, 67 (4), e86-e89. doi: 10.1097/mat.0000000000001237
2020
Journal Article
Extracorporeal Life Support Organization Coronavirus Disease 2019 Interim Guidelines: A Consensus Document from an International Group of Interdisciplinary Extracorporeal Membrane Oxygenation Providers
Shekar, Kiran, Badulak, Jenelle, Peek, Giles, Boeken, Udo, Dalton, Heidi J., Arora, Lovkesh, Zakhary, Bishoy, Ramanathan, Kollengode, Starr, Joanne, Akkanti, Bindu, Antonini, M. Velia, Ogino, Mark T., Raman, Lakshmi, on behalf of the ELSO Guideline Working Group, Barret, Nicholas, Brodie, Daniel, Combes, Alain, Lorusso, Roberto, MacLaren, Graeme, Müller, Thomas, Paden, Matthew and Pellegrino, Vincent (2020). Extracorporeal Life Support Organization Coronavirus Disease 2019 Interim Guidelines: A Consensus Document from an International Group of Interdisciplinary Extracorporeal Membrane Oxygenation Providers. ASAIO Journal, 66 (7), 707-721. doi: 10.1097/MAT.0000000000001193
2020
Journal Article
Albumin use after cardiac surgery
Matebele, Mbakise P., Ramanan, Mahesh, Thompson, Kelly, Cornmell, George, Naidoo, Rishendran V. and Shekar, Kiran (2020). Albumin use after cardiac surgery. Critical Care Explorations, 2 (7), e0164. doi: 10.1097/CCE.0000000000000164
2020
Journal Article
ECMO use in COVID-19: lessons from past respiratory virus outbreaks-a narrative review
Cho, Hwa Jin, Heinsar, Silver, Jeong, In Seok, Shekar, Kiran, Li Bassi, Gianluigi, Jung, Jae Seung, Suen, Jacky Y. and Fraser, John F. (2020). ECMO use in COVID-19: lessons from past respiratory virus outbreaks-a narrative review. Critical Care, 24 (1) 301, 301. doi: 10.1186/s13054-020-02979-3
2020
Journal Article
Blood transfusion strategies and ECMO during the COVID-19 pandemic – Authors' reply
Ramanathan, Kollengode, MacLaren, Graeme, Combes, Alain, Brodie, Daniel and Shekar, Kiran (2020). Blood transfusion strategies and ECMO during the COVID-19 pandemic – Authors' reply. The Lancet Respiratory Medicine, 8 (5), e41-E41. doi: 10.1016/S2213-2600(20)30174-0
2020
Journal Article
Planning and provision of ECMO services for severe ARDS during the COVID-19 pandemic and other outbreaks of emerging infectious diseases
Ramanathan, Kollengode, Antognini, David, Combes, Alain, Paden, Matthew, Zakhary, Bishoy, Ogino, Mark, MacLaren, Graeme, Brodie, Daniel and Shekar, Kiran (2020). Planning and provision of ECMO services for severe ARDS during the COVID-19 pandemic and other outbreaks of emerging infectious diseases. The Lancet Respiratory Medicine, 8 (5), 518-526. doi: 10.1016/S2213-2600(20)30121-1
2020
Journal Article
Treading lightly in a pandemic: #Zentensivist reflections on COVID-19
Siuba, Matthew T., Dugar, Siddharth and Shekar, Kiran (2020). Treading lightly in a pandemic: #Zentensivist reflections on COVID-19. Chest, 158 (2), 471-473. doi: 10.1016/j.chest.2020.04.013
Supervision
Availability
- Professor Kiran Shekar is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
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Doctor Philosophy
Single Hand Used inTubaTing Laryngoscope Evaluation (SHUTTLE) Project
Associate Advisor
Other advisors: Emeritus Professor Jeffrey Lipman
Completed supervision
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2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Associate Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Professor Jason Roberts
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2019
Doctor Philosophy
Bioanalytical method development and validation to investigate cytochrome P450 mediated drug metabolism in patients receiving extracorporeal life support.
Associate Advisor
Other advisors: Emeritus Professor Maree Smith
Media
Enquiries
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