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Professor Kiran Shekar
Professor

Kiran Shekar

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Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 350 peer-reviewed journal articles, 60 conference abstracts, 14 book chapters and has delivered over 150 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

332 works between 2008 and 2026

181 - 200 of 332 works

2021

Journal Article

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

2021

Journal Article

Implementation of new ECMO centers during the COVID-19 pandemic: experience and results from the Middle East and India

Rabie, Ahmed A., Azzam, Mohamed H., Al-Fares, Abdulrahman A., Abdelbary, Akram, Mufti, Hani N., Hassan, Ibrahim F., Chakraborty, Arpan, Oza, Pranay, Elhazmi, Alyaa, Alfoudri, Huda, Pooboni, Suneel Kumar, Alharthy, Abdulrahman, Brodie, Daniel, Zakhary, Bishoy, Shekar, Kiran, Antonini, Marta Velia, Barrett, Nicholas A., Peek, Giles, Combes, Alain and Arabi, Yaseen M. (2021). Implementation of new ECMO centers during the COVID-19 pandemic: experience and results from the Middle East and India. Intensive Care Medicine, 47 (8), 887-895. doi: 10.1007/s00134-021-06451-w

Implementation of new ECMO centers during the COVID-19 pandemic: experience and results from the Middle East and India

2021

Journal Article

Development and implementation of a clinical information system–based protocol to improve nurse satisfaction of end-of-life care in a single intensive care unit

Pachchigar, R., Blackwell, N., Webb, L., Francis, K., Pahor, K., Thompson, A., Cornmell, G., Anstey, C., Ziegenfuss, M. and Shekar, K. (2021). Development and implementation of a clinical information system–based protocol to improve nurse satisfaction of end-of-life care in a single intensive care unit. Australian Critical Care, 35 (3), 273-278. doi: 10.1016/j.aucc.2021.05.003

Development and implementation of a clinical information system–based protocol to improve nurse satisfaction of end-of-life care in a single intensive care unit

2021

Journal Article

A systematic review of the incidence and outcomes of in-hospital cardiac arrests in patients with voronavirus disease 2019

Lim, Zheng Jie, Ponnapa Reddy, Mallikarjuna, Curtis, J. Randall, Afroz, Afsana, Billah, Baki, Sheth,, Vishad, Hayek, Salim S., Leaf, David E., Miles, Jeremy A., Shah, Priyank, Yuriditsky, Eugene, Jones, Daryl, Shekar, Kiran and Subramaniam, Ashwin (2021). A systematic review of the incidence and outcomes of in-hospital cardiac arrests in patients with voronavirus disease 2019. Critical Care Medicine, 49 (6), 901-911. doi: 10.1097/ccm.0000000000004950

A systematic review of the incidence and outcomes of in-hospital cardiac arrests in patients with voronavirus disease 2019

2021

Journal Article

Management of adult patients supported with venovenous extracorporeal membrane oxygenation (VV ECMO): guideline from the Extracorporeal Life Support Organization (ELSO)

Tonna, Joseph E., Abrams, Darryl, Brodie, Daniel, Greenwood, John C., Rubio Mateo-Sidron, Jose Alfonso, Usman, Asad, Fan, Eddy, Barrett, Nicholas, Schmidt, Matthieu, Mueller, Thomas, Combes, Alain and Shekar, Kiran (2021). Management of adult patients supported with venovenous extracorporeal membrane oxygenation (VV ECMO): guideline from the Extracorporeal Life Support Organization (ELSO). ASAIO Journal, 67 (6), 601-610. doi: 10.1097/MAT.0000000000001432

Management of adult patients supported with venovenous extracorporeal membrane oxygenation (VV ECMO): guideline from the Extracorporeal Life Support Organization (ELSO)

2021

Journal Article

Ceftriaxone exposure in patients undergoing extracorporeal membrane oxygenation

Gijsen, Matthias, Annaert, Pieter, Shekar, Kiran, Roberts, Jason A., Wauters, Joost and Spriet, Isabel (2021). Ceftriaxone exposure in patients undergoing extracorporeal membrane oxygenation. International Journal of Antimicrobial Agents, 57 (5) 106326, 106326. doi: 10.1016/j.ijantimicag.2021.106326

Ceftriaxone exposure in patients undergoing extracorporeal membrane oxygenation

2021

Journal Article

ECMO for COVID-19: Updated 2021 Guidelines from the Extracorporeal Life Support Organization (ELSO)

Badulak, Jenelle, Antonini, M. Velia, Stead, Christine M., Shekerdemian, Lara, Raman, Lakshmi, Paden, Matthew L., Agerstrand, Cara, Bartlett, Robert H., Barrett, Nicholas, Combes, Alain, Lorusso, Roberto, Mueller, Thomas, Ogino, Mark T., Peek, Giles, Pellegrino, Vincent, Rabie, Ahmed A., Salazar, Leonardo, Schmidt, Matthieu, Shekar, Kiran, MacLaren, Graeme and Brodie, Daniel (2021). ECMO for COVID-19: Updated 2021 Guidelines from the Extracorporeal Life Support Organization (ELSO). ASAIO Journal, 67 (5), 485-495. doi: 10.1097/MAT.0000000000001422

ECMO for COVID-19: Updated 2021 Guidelines from the Extracorporeal Life Support Organization (ELSO)

2021

Journal Article

Long-term outcome of prolonged critical illness: a multicentered study in North Brisbane, Australia

Laupland, Kevin B., Ramanan, Mahesh, Shekar, Kiran, Edwards, Felicity, Clement, Pierre and Tabah, Alexis (2021). Long-term outcome of prolonged critical illness: a multicentered study in North Brisbane, Australia. PLoS One, 16 (4) e0249840, e0249840. doi: 10.1371/journal.pone.0249840

Long-term outcome of prolonged critical illness: a multicentered study in North Brisbane, Australia

2021

Journal Article

Personal protective equipment preparedness in intensive care units during the coronavirus disease 2019 pandemic: an Asia-Pacific follow-up survey

Gullapalli, Navya, Jie Lim, Zheng, Ramanathan, Kollengode, Bihari, Shailesh, Haji, Jumana, Shekar, Kiran, Tat Wong, Wai, Rajamani, Arvind and Subramaniam, Ashwin (2021). Personal protective equipment preparedness in intensive care units during the coronavirus disease 2019 pandemic: an Asia-Pacific follow-up survey. Australian Critical Care, 35 (1), 5-12. doi: 10.1016/j.aucc.2021.02.007

Personal protective equipment preparedness in intensive care units during the coronavirus disease 2019 pandemic: an Asia-Pacific follow-up survey

2021

Journal Article

Elevated Venous to Arterial Carbon Dioxide Gap and Anion Gap Are Associated with Poor Outcome in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support

McDonald, Charles I., Brodie, Daniel, Schmidt, Matthieu, Hay, Karen and Shekar, Kiran (2021). Elevated Venous to Arterial Carbon Dioxide Gap and Anion Gap Are Associated with Poor Outcome in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support. ASAIO Journal, 67 (3), 263-269. doi: 10.1097/mat.0000000000001215

Elevated Venous to Arterial Carbon Dioxide Gap and Anion Gap Are Associated with Poor Outcome in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support

2021

Journal Article

Prone positioning of patients during venovenous extracorporeal membrane oxygenation

Shekar, Kiran, Ramanathan, Kollengode and Brodie, Daniel (2021). Prone positioning of patients during venovenous extracorporeal membrane oxygenation. Annals of the American Thoracic Society, 18 (3), 421-423. doi: 10.1513/AnnalsATS.202011-1444ED

Prone positioning of patients during venovenous extracorporeal membrane oxygenation

2021

Journal Article

Venoarterial extracorporeal membrane oxygenation for postcardiotomy shock - analysis of the extracorporeal life support organization registry

Kowalewski, Mariusz, Zieliński, Kamil, Brodie, Daniel, MacLaren, Graeme, Whitman, Glenn, Raffa, Giuseppe M., Boeken, Udo, Shekar, Kiran, Chen, Yih-Sharng, Bermudez, Christian, D'Alessandro, David, Hou, Xiaotong, Haft, Jonathan, Belohlavek, Jan, Dziembowska, Inga, Suwalski, Piotr, Alexander, Peta, Barbaro, Ryan P., Gaudino, Mario, Di Mauro, Michele, Maessen, Jos and Lorusso, Roberto (2021). Venoarterial extracorporeal membrane oxygenation for postcardiotomy shock - analysis of the extracorporeal life support organization registry. Critical Care Medicine, 49 (7), 1-11. doi: 10.1097/CCM.0000000000004922

Venoarterial extracorporeal membrane oxygenation for postcardiotomy shock - analysis of the extracorporeal life support organization registry

2021

Journal Article

Extracorporeal membrane oxygenation and coronavirus disease 2019

Shekar, Kiran, Worku, Elliott and Brodie, Daniel (2021). Extracorporeal membrane oxygenation and coronavirus disease 2019. JAMA Surgery, 156 (4), 400-401. doi: 10.1001/jamasurg.2020.6631

Extracorporeal membrane oxygenation and coronavirus disease 2019

2021

Journal Article

Intensive care digital health response to emerging infectious disease outbreaks such as COVID-19

Kirrane, Marianne D., Shrapnel, Sally, Ramanan, Mahesh, Clement, Pierre, Fraser, John F., Laupland, Kevin B., Sullivan, Clair M. and Shekar, Kiran (2021). Intensive care digital health response to emerging infectious disease outbreaks such as COVID-19. Anaesthesia and Intensive Care, 49 (2), 0310057X2097577-111. doi: 10.1177/0310057x20975777

Intensive care digital health response to emerging infectious disease outbreaks such as COVID-19

2021

Journal Article

Concurrent use of renal replacement therapy during extracorporeal membrane oxygenation support: a systematic review and meta-analysis

Mitra, Saikat, Ling, Ryan Ruiyang, Tan, Chuen Seng, Shekar, Kiran, MacLaren, Graeme and Ramanathan, Kollengode (2021). Concurrent use of renal replacement therapy during extracorporeal membrane oxygenation support: a systematic review and meta-analysis. Journal of Clinical Medicine, 10 (2) 241, 241-13. doi: 10.3390/jcm10020241

Concurrent use of renal replacement therapy during extracorporeal membrane oxygenation support: a systematic review and meta-analysis

2021

Journal Article

Current understanding of leukocyte phenotypic and functional modulation during extracorporeal membrane oxygenation: a narrative review

Ki, Katrina K., Millar, Jonathan E., Langguth, Daman, Passmore, Margaret R., McDonald, Charles I., Shekar, Kiran, Shankar-Hari, Manu, Cho, Hwa Jin, Suen, Jacky Y. and Fraser, John F. (2021). Current understanding of leukocyte phenotypic and functional modulation during extracorporeal membrane oxygenation: a narrative review. Frontiers in Immunology, 11 600684, 600684. doi: 10.3389/fimmu.2020.600684

Current understanding of leukocyte phenotypic and functional modulation during extracorporeal membrane oxygenation: a narrative review

2021

Journal Article

Impact of an aerosol box on time to tracheal intubation: systematic review and meta-analysis

Lim, Zheng Jie, Ponnapa Reddy, Mallikarjuna, Karalapillai, Dharshi, Shekar, Kiran and Subramaniam, Ashwin (2021). Impact of an aerosol box on time to tracheal intubation: systematic review and meta-analysis. British Journal of Anaesthesia, 126 (3), e122-e125. doi: 10.1016/j.bja.2020.11.036

Impact of an aerosol box on time to tracheal intubation: systematic review and meta-analysis

2021

Journal Article

Prone positioning of nonintubated patients with Coronavirus disease 2019 - A systematic review and meta-analysis

Ponnapa Reddy, Mallikarjuna, Subramaniam, Ashwin, Afroz, Afsana, Billah, Baki, Lim, Zheng Jie, Zubarev, Alexandr, Blecher, Gabriel, Tiruvoipati, Ravindranath, Ramanathan, Kollengode, Wong, Suei Nee, Brodie, Daniel, Fan, Eddy and Shekar, Kiran (2021). Prone positioning of nonintubated patients with Coronavirus disease 2019 - A systematic review and meta-analysis. Critical Care Medicine, 49 (10), E1001-E1014. doi: 10.1097/CCM.0000000000005086

Prone positioning of nonintubated patients with Coronavirus disease 2019 - A systematic review and meta-analysis

2021

Journal Article

Cytokine adsorption during ECMO for COVID-19-related ARDS

Shekar, Kiran, McAuley, Daniel F and Brodie, Daniel (2021). Cytokine adsorption during ECMO for COVID-19-related ARDS. The Lancet Respiratory Medicine, 9 (7), 680-682. doi: 10.1016/S2213-2600(21)00207-1

Cytokine adsorption during ECMO for COVID-19-related ARDS

2020

Journal Article

The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit

Passmore, Margaret R., Ki, Katrina K., Chan, Chris H. H., Lee, Talvin, Bouquet, Mahé, Wood, Emily S., Raman, Sainath, Rozencwajg, Sacha, Burrell, Aidan J. C., McDonald, Charles I., Langguth, Daman, Shekar, Kiran, Malfertheiner, Maximilian V., Fraser, John F. and Suen, Jacky Y. (2020). The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit. Artificial Organs, 44 (12) aor.13771, 1276-1285. doi: 10.1111/aor.13771

The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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