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Professor Kiran Shekar
Professor

Kiran Shekar

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Overview

Background

Shekar is a Senior Intensive Care Specialist and the Director of Research in the Adult Intensive Care Service at the Prince Charles Hospital. He holds academic appointments as a Professor at the University of Queensland, Adjunct Professor at Queensland University of Technology and Associate Professor at Bond University, Gold Coast. Shekar is the recipient of the Metro North Hospital and Health Service Clinician Research Fellowship and the Queeensland Health Research Fellowship. Shekar specialises in the design and conduct of both pre-clinical and clinical studies. His ongoing research programs, “The NO Tube Project” and “ The Budget ICU Project”, bring together clinicians, multidisciplinary allied health professionals, engineers, scientists, health economists, industry and policy experts to minimise the burden of invasive mechanical ventilation in intensive care units and to improve access to intensive care services around the world. His current body of research includes the pathophysiology of cardiorespiratory failure, sepsis and extracorporeal life support (ECLS). Shekar has significant experience in conducting mechanistic research in large animal models of lung injury, mechanical ventilation, sepsis and ECLS. His pioneering work in drug pharmacokinetics in adult patients on ECLS was recognised globally. He is the chief investigator of an ongoing international multi-centre clinical study that aims to develop drug dosing guidelines for ECLS patients. Shekar has secured over $20 million in grant funding, published over 300 peer-reviewed articles, 60 conference abstracts, 14 book chapters and has delivered over 100 national and international lectures. He regularly reviews articles for leading journals and competitive grant applications. He is routinely involved with bedside teaching and simulation exercises, as well as supervision of RHD students. Shekar has collaborated extensively both nationally and internationally. He is a member of the Scientific Committee of the International ECMO Network. He is the global research lead for Extracorporeal Life Support Organisation (ELSO) Education Taskforce and is a member of the Asia-Pacific ELSO Steering and Education Committee. He is also the Chair of the global ELSO COVID-19 working group. Shekar contributes to the Australia and New Zealand Intensive Care Society COVID-19 Guideline Committee and is the Co-Chair of the National COVID-19 Clinical Evidence Taskforce Hospital and Acute Care Panel. He has significant experience with Clinical Information Systems (CIS) and is the Chair of the CIS Special User Group in Queensland.

Availability

Professor Kiran Shekar is:
Available for supervision
Media expert

Research interests

  • Extracorporeal membrane oxygenation

  • Respiratory failure and minimising the burden of invasive mechanical ventilation

  • PK/PD on Extracorporeal membrane oxygenation support

  • Cardiogenic Shock and Mechanical Circulatory Support

  • Microcirculation on temporary Mechanical Circulatory Support

  • Building a budget intensive care unit to improve intensive care access in resource poor countries

  • Standardising ECMO education to bridge the variability in global ECMO outcomes

Works

Search Professor Kiran Shekar’s works on UQ eSpace

308 works between 2008 and 2025

101 - 120 of 308 works

2023

Journal Article

Optimal settings at initiation of veno-venous extracorporeal membrane oxygenation: An exploratory in-silico study

Joyce, Christopher J., Shekar, Kiran and Walsham, James (2023). Optimal settings at initiation of veno-venous extracorporeal membrane oxygenation: An exploratory in-silico study. ASAIO Journal, 69 (1), E28-E34. doi: 10.1097/MAT.0000000000001849

Optimal settings at initiation of veno-venous extracorporeal membrane oxygenation: An exploratory in-silico study

2023

Journal Article

90-day case-fatality in critically ill patients with chronic liver disease influenced by presence of portal hypertension, results from a multicentre retrospective cohort study

White, Kyle, Tabah, Alexis, Ramanan, Mahesh, Shekar, Kiran, Edwards, Felicity and Laupland, Kevin B. (2023). 90-day case-fatality in critically ill patients with chronic liver disease influenced by presence of portal hypertension, results from a multicentre retrospective cohort study. Journal of Intensive Care Medicine, 38 (1), 1-10. doi: 10.1177/08850666221100408

90-day case-fatality in critically ill patients with chronic liver disease influenced by presence of portal hypertension, results from a multicentre retrospective cohort study

2023

Book Chapter

Ethical challenges and quality assurance of extracorporeal membrane oxygenation

Ramanathan, Kollengode, Shekar, Kiran and Dhundi, Ujwal (2023). Ethical challenges and quality assurance of extracorporeal membrane oxygenation. Cardiopulmonary bypass: advances in extracorporeal life support. (pp. 1023-1031) Amsterdam: Academic Press. doi: 10.1016/b978-0-443-18918-0.00065-6

Ethical challenges and quality assurance of extracorporeal membrane oxygenation

2023

Book Chapter

Extracorporeal life support in accidental hypothermia

Mitra, Saikat, Swol, Justyna, Ramanathan, Kollengode and Shekar, Kiran (2023). Extracorporeal life support in accidental hypothermia. Cardiopulmonary bypass: advances in extracorporeal life support. (pp. 1187-1195) edited by Kaan Kırali, Joseph S. Coselli and Afksendiyos Kalangos. Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-443-18918-0.00076-0

Extracorporeal life support in accidental hypothermia

2022

Journal Article

Reply to Fillatre, et al. and Li, et al

Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2022). Reply to Fillatre, et al. and Li, et al. American Journal of Respiratory and Critical Care Medicine, 207 (7), 952-953. doi: 10.1164/rccm.202211-2140LE

Reply to Fillatre, et al. and Li, et al

2022

Journal Article

Outcomes of prolonged ICU stay for patients undergoing cardiac surgery in Australia and New Zealand

Shah, Vikram, Ahuja, Abhilasha, Kumar, Aashish, Anstey, Chris, Thang, Christopher, Guo, Linda, Shekar, Kiran and Ramanan, Mahesh (2022). Outcomes of prolonged ICU stay for patients undergoing cardiac surgery in Australia and New Zealand. Journal of Cardiothoracic and Vascular Anesthesia, 36 (12), 4313-4319. doi: 10.1053/j.jvca.2022.08.026

Outcomes of prolonged ICU stay for patients undergoing cardiac surgery in Australia and New Zealand

2022

Journal Article

Respiratory system mechanics, gas exchange, and outcomes in mechanically ventilated patients with COVID-19-related acute respiratory distress syndrome: a systematic review and meta-analysis

Reddy, Mallikarjuna Ponnapa, Subramaniam, Ashwin, Chua, Clara, Ling, Ryan Ruiyang, Anstey, Christopher, Ramanathan, Kollengode, Slutsky, Arthur S and Shekar, Kiran (2022). Respiratory system mechanics, gas exchange, and outcomes in mechanically ventilated patients with COVID-19-related acute respiratory distress syndrome: a systematic review and meta-analysis. The Lancet Respiratory Medicine, 10 (12), 1178-1188. doi: 10.1016/s2213-2600(22)00393-9

Respiratory system mechanics, gas exchange, and outcomes in mechanically ventilated patients with COVID-19-related acute respiratory distress syndrome: a systematic review and meta-analysis

2022

Journal Article

A novel barrier device and method for protection against airborne pathogens during endotracheal intubation

Alonso, Julio M., Lipman, Jeffrey and Shekar, Kiran (2022). A novel barrier device and method for protection against airborne pathogens during endotracheal intubation. European Journal of Anaesthesiology, 39 (11), 900-903. doi: 10.1097/EJA.0000000000001731

A novel barrier device and method for protection against airborne pathogens during endotracheal intubation

2022

Journal Article

Need for tracheostomy in major head and neck ablative surgery: a paradigm shift during the COVID-19 pandemic

Quach, H., McGuire, B., Wallace, C. and Shekar, K. (2022). Need for tracheostomy in major head and neck ablative surgery: a paradigm shift during the COVID-19 pandemic. Annals of the Royal College of Surgeons of England, 104 (9), 700-702. doi: 10.1308/rcsann.2021.0327

Need for tracheostomy in major head and neck ablative surgery: a paradigm shift during the COVID-19 pandemic

2022

Journal Article

Impact of frailty on clinical outcomes in patients with and without COVID-19 pneumonitis admitted to intensive care units in Australia and New Zealand: a retrospective registry data analysis

Subramaniam, Ashwin, Shekar, Kiran, Anstey, Christopher, Tiruvoipati, Ravindranath and Pilcher, David (2022). Impact of frailty on clinical outcomes in patients with and without COVID-19 pneumonitis admitted to intensive care units in Australia and New Zealand: a retrospective registry data analysis. Critical Care, 26 (1) 301, 1-12. doi: 10.1186/s13054-022-04177-9

Impact of frailty on clinical outcomes in patients with and without COVID-19 pneumonitis admitted to intensive care units in Australia and New Zealand: a retrospective registry data analysis

2022

Journal Article

Invasive mechanical ventilation in patients with acute respiratory distress syndrome receiving extracorporeal support: a narrative review of strategies to mitigate lung injury

Zochios, V., Brodie, D., Shekar, K., Schultz, M. J. and Parhar, K. K.S. (2022). Invasive mechanical ventilation in patients with acute respiratory distress syndrome receiving extracorporeal support: a narrative review of strategies to mitigate lung injury. Anaesthesia, 77 (10), 1137-1151. doi: 10.1111/anae.15806

Invasive mechanical ventilation in patients with acute respiratory distress syndrome receiving extracorporeal support: a narrative review of strategies to mitigate lung injury

2022

Journal Article

Microaxial left ventricular assist device in cardiogenic shock: a systematic review and meta-analysis

Tan, Shien Ru, Low, Christopher Jer Wei, Ng, Wei Lin, Ling, Ryan Ruiyang, Tan, Chuen Seng, Lim, Shir Lynn, Cherian, Robin, Lin, Weiqin, Shekar, Kiran, Mitra, Saikat, MacLaren, Graeme and Ramanathan, Kollengode (2022). Microaxial left ventricular assist device in cardiogenic shock: a systematic review and meta-analysis. Life, 12 (10) 1629, 1-16. doi: 10.3390/life12101629

Microaxial left ventricular assist device in cardiogenic shock: a systematic review and meta-analysis

2022

Journal Article

The impact of reduction in intensity of mechanical ventilation upon venovenous ECMO initiation on radiographically assessed lung edema scores: a retrospective observational study

Worku, Elliott T., Yeung, Francis, Anstey, Chris and Shekar, Kiran (2022). The impact of reduction in intensity of mechanical ventilation upon venovenous ECMO initiation on radiographically assessed lung edema scores: a retrospective observational study. Frontiers in Medicine, 9 1005192, 1-10. doi: 10.3389/fmed.2022.1005192

The impact of reduction in intensity of mechanical ventilation upon venovenous ECMO initiation on radiographically assessed lung edema scores: a retrospective observational study

2022

Book Chapter

Pharmacology

Kirk, Christa Jefferis, Abdul-Aziz, Mohd H., Roberts, Jason A., Valencia, Eleonore, Watt, Kevin, MacLaren, Graeme and Shekar, Kiran (2022). Pharmacology. Extracorporeal life support: The ELSO red book. (pp. 643-654) edited by Graeme Maclaren, Daniel Brodie, Roberto Lorusso, Giles Peek, Ravi Thiagarajan and Leen Vercaemst. Ann Arbor, MI, United States: Extracorporeal Life Support Organization.

Pharmacology

2022

Journal Article

Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software

Roberts, Jason A., Bellomo, Rinaldo, Cotta, Menino O., Koch, Birgit C. P., Lyster, Haifa, Ostermann, Marlies, Roger, Claire, Shekar, Kiran, Watt, Kevin and Abdul-Aziz, Mohd H. (2022). Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software. Intensive Care Medicine, 48 (10), 1338-1351. doi: 10.1007/s00134-022-06847-2

Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software

2022

Journal Article

Direct oral anticoagulants in atrial fibrillation following cardiac surgery: a systematic review and meta-analysis with trial sequential analysis

Koh, Kylynn K., Ling, Ryan R., Tan, Shaun Y.S., Chen, Ying, Fan, Bingwen E., Shekar, Kiran, Sule, Jai A., Subbian, Senthil K. and Ramanathan, Kollengode (2022). Direct oral anticoagulants in atrial fibrillation following cardiac surgery: a systematic review and meta-analysis with trial sequential analysis. British Journal of Anaesthesia, 129 (2), 154-162. doi: 10.1016/j.bja.2022.05.010

Direct oral anticoagulants in atrial fibrillation following cardiac surgery: a systematic review and meta-analysis with trial sequential analysis

2022

Journal Article

Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers

Subramaniam, Ashwin, Reddy, Mallikarjuna, Kadam, Umesh, Zubarev, Alexander, Lim, Zheng, Anstey, Chris, Bihari, Shailesh, Haji, Jumana, Luo, Jinghang, Mitra, Saikat, Ramanathan, Kollengode, Rajamani, Arvind, Rubulotta, Francesca, Svensk, Erik and Shekar, Kiran (2022). Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers. Australian Critical Care, 35 (4), 415-423. doi: 10.1016/j.aucc.2021.06.015

Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers

2022

Journal Article

SARS-CoV-2 transmission risk to healthcare workers performing tracheostomies: a systematic review

Subramaniam, Ashwin, Lim, Zheng Jie, Ponnapa Reddy, Mallikarjuna, Mitchell, Hayden and Shekar, Kiran (2022). SARS-CoV-2 transmission risk to healthcare workers performing tracheostomies: a systematic review. ANZ Journal of Surgery, 92 (7-8), 1614-1625. doi: 10.1111/ans.17814

SARS-CoV-2 transmission risk to healthcare workers performing tracheostomies: a systematic review

2022

Journal Article

Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

Cheng, Vesa, Abdul-Aziz, Mohd H., Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Levkovich, Bianca J., Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Roberts, Jason A., Shekar, Kiran, Fraser, John F. and ASAP ECMO Investigators (2022). Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study). Anaesthesia Critical Care and Pain Medicine, 41 (3) 101080, 1-6. doi: 10.1016/j.accpm.2022.101080

Population pharmacokinetics of ciprofloxacin in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study)

2022

Journal Article

Reply Letter to the Editor Regarding the ELSO Interim Guidelines for Veno-Arterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients

Lorusso, Roberto, Bartlett, Robert H., Shekar, Kiran, MacLaren, Graeme, Schmidt, Matthieu, Pellegrino, Vincent, Meyns, Bart, Haft, Jonathan, Vercaemst, Leen, Pappalardo, Federico, Bermudez, Christian, Belohlavek, Jan, Hou, Xiaotong, Boeken, Udo, Castillo, Roberto, Donker, Dirk W., Abrams, Darryl, Ranucci, Marco, Hryniewicz, Kasia, Chavez, Ivan, Chen, Yih-Sharng, Salazar, Leonardo and Whitman, Glenn (2022). Reply Letter to the Editor Regarding the ELSO Interim Guidelines for Veno-Arterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients. ASAIO Journal, 68 (6), E111-E112. doi: 10.1097/MAT.0000000000001701

Reply Letter to the Editor Regarding the ELSO Interim Guidelines for Veno-Arterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients

Funding

Current funding

  • 2025 - 2030
    Integrating sequencing technologies for bloodstream infection and sepsis diagnostics in critically-ill patients
    NHMRC MRFF Genomics Health Futures Mission
    Open grant
  • 2025 - 2030
    ROAD RCT: Resistance Optimised Antibiotic Dosing in critically ill patients - a Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2023 - 2028
    A national critical care research platform to ensure high quality sepsis care in Australian ICUs (MRFF EMCR led by Monash University)
    Monash University
    Open grant
  • 2022 - 2026
    PRecision Ecmo in CardIogenic Shock Evaluation: PRECISE Study (MRFF grant administered by Monash University)
    Monash University
    Open grant

Past funding

  • 2019
    Establishing UQ Centre for Clinical Research as the centre for Aerosol therapy in critical care by optimising particle size of aerosols for effective drug delivery.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant

Supervision

Availability

Professor Kiran Shekar is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Single Hand Used inTubaTing Laryngoscope Evaluation (SHUTTLE) Project

    Associate Advisor

    Other advisors: Professor Jeffrey Lipman

Completed supervision

Media

Enquiries

Contact Professor Kiran Shekar directly for media enquiries about their areas of expertise.

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