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Emeritus Professor Robert Tindle
Emeritus Professor

Robert Tindle

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Overview

Availability

Emeritus Professor Robert Tindle is:
Available for supervision
Media expert

Qualifications

  • Bachelor (Honours) of Science (Advanced), Institution to be confirmed
  • Doctor of Philosophy, University College London

Research impacts

The CD34 stem cell has replaced marrow transplation in the treatment of leukaemias and other diseases throughout the world.

The tolerogenic effect of the HPV 16 E7 oncoprotein informs the design of therapeutic vaccines for human cervical cancer.

Works

Search Professor Robert Tindle’s works on UQ eSpace

105 works between 1975 and 2024

61 - 80 of 105 works

1995

Journal Article

Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a production

Fernando, Germain J. P., Stenzel, Deborah J., Tindle, Robert W., Merza, Malik S., Morein, Bror and Frazer, Ian H. (1995). Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a production. Vaccine, 13 (15), 1460-1467. doi: 10.1016/0264-410X(95)00029-Z

Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a production

1994

Journal Article

Cell-mediated immune responses to E7 peptides of human papillomavirus (HPV) type 16 are dependent on the HPV type infecting the cervix whereas serological reactivity is not type-specific

Kadish, Anna S., Romney, Seymour L., Ledwidge, Richard, Tindle, Robert, Fernando, Germain J. P., Zee, Sui Y., Van Ranst, Marc A. and Burk, Robert D. (1994). Cell-mediated immune responses to E7 peptides of human papillomavirus (HPV) type 16 are dependent on the HPV type infecting the cervix whereas serological reactivity is not type-specific. Journal of General Virology, 75 (9), 2277-2284. doi: 10.1099/0022-1317-75-9-2277

Cell-mediated immune responses to E7 peptides of human papillomavirus (HPV) type 16 are dependent on the HPV type infecting the cervix whereas serological reactivity is not type-specific

1994

Journal Article

Cell-Mediated Immune-Responses to E7 Peptides of Human Papillomavirus (hpv) Type-16 Are Dependent On the Hpv Type Infecting the Cervix Whereas Serological Reactivity Is Not Type-Specific

Kadish, A. S., Romney, S. L., Ledwidge, R., Tindle, R., Fernando, G. J. P., Zee, S. Y., Vanranst, M. A. and Burk, R. D. (1994). Cell-Mediated Immune-Responses to E7 Peptides of Human Papillomavirus (hpv) Type-16 Are Dependent On the Hpv Type Infecting the Cervix Whereas Serological Reactivity Is Not Type-Specific. Journal of General Virology, 75, 2277-2284. doi: 10.1099/0022-1317-75-9-2277

Cell-Mediated Immune-Responses to E7 Peptides of Human Papillomavirus (hpv) Type-16 Are Dependent On the Hpv Type Infecting the Cervix Whereas Serological Reactivity Is Not Type-Specific

1994

Journal Article

Human Papillomavirus (Hpv) Type-18 E7 Protein Is a Short-Lived Steroid-Inducible Phosphoprotein in Hpv-Transformed Cell-Lines

Selvey, L. A., Dunn, L. A., Tindle, R. W., Park, D. S. and Frazer, I. H. (1994). Human Papillomavirus (Hpv) Type-18 E7 Protein Is a Short-Lived Steroid-Inducible Phosphoprotein in Hpv-Transformed Cell-Lines. Journal of General Virology, 75 (7), 1647-1653. doi: 10.1099/0022-1317-75-7-1647

Human Papillomavirus (Hpv) Type-18 E7 Protein Is a Short-Lived Steroid-Inducible Phosphoprotein in Hpv-Transformed Cell-Lines

1994

Conference Publication

A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer

Frazer, I. H., Lieppe, D., Lambert, P., Griep, A., Dunn, L., Tindle, R. W. and Fernando, G. (1994). A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer. Keystone Symposia on Molecular & Cellular Biology, Taos, New Mexico , 13 - 20 February 1994. NEW YORK: Wiley-Blackwell.

A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer

1994

Conference Publication

Use of a Double Aro Salmonella Mutant to Stably Express Hbv16 E7 Protein Epitopes Carried by the Hbv Core Antigen

Londono, P., Chatfield, S., Tindle, R., Frazer, I. and Dougan, G. (1994). Use of a Double Aro Salmonella Mutant to Stably Express Hbv16 E7 Protein Epitopes Carried by the Hbv Core Antigen. In: Journal of Cellular Biochemistry. Keystone Symposia on Molecular & Cellular Biology, Taos, New Mexico , (232-232). 13 - 20 February 1994.

Use of a Double Aro Salmonella Mutant to Stably Express Hbv16 E7 Protein Epitopes Carried by the Hbv Core Antigen

1994

Journal Article

Immune response to human papillomaviruses and the prospects for human papillomavirus-specific immunisation

Tindle, R. W. and Frazer, I. H. (1994). Immune response to human papillomaviruses and the prospects for human papillomavirus-specific immunisation. Current Topics in Microbiology and Immunology, 186, 217-253. doi: 10.1007/978-3-642-78487-3_12

Immune response to human papillomaviruses and the prospects for human papillomavirus-specific immunisation

1994

Conference Publication

Small Synthetic Peptides as Vaccines - a Model Peptide Iscom Construct From Cancer-Associated Human Papillomavirus

Fernando, G. J. P., Tindle, R. W., Frazer, I. H., Stenzel, D. J., Merza, M. S. and Morein, B. (1994). Small Synthetic Peptides as Vaccines - a Model Peptide Iscom Construct From Cancer-Associated Human Papillomavirus. 11th Annual Meeting on Modern Approaches to New Vaccines, Cold Spring Harbor, NY United States, September 1993. PLAINVIEW: COLD SPRING HARBOR LABORATORY PRESS.

Small Synthetic Peptides as Vaccines - a Model Peptide Iscom Construct From Cancer-Associated Human Papillomavirus

1994

Journal Article

Chimeric hepatitis B core antigen particles containing B- and Th-epitopes of human papillomavirus type 16 E7 protein induce specific antibody and T-helper responses in immunised mice

Tindle, Robert W., Herd, Karen, Londoño, Patricia, Fernando, Germain J. P., Chatfield, Steven N., Malcolm, Karen and Dougan, Gordon (1994). Chimeric hepatitis B core antigen particles containing B- and Th-epitopes of human papillomavirus type 16 E7 protein induce specific antibody and T-helper responses in immunised mice. Virology, 200 (2), 547-557. doi: 10.1006/viro.1994.1217

Chimeric hepatitis B core antigen particles containing B- and Th-epitopes of human papillomavirus type 16 E7 protein induce specific antibody and T-helper responses in immunised mice

1993

Conference Publication

Adjuvants Can Bias to Th1 or Th2 the Immune-Response to Hpv E7 Protein in Mice

Fernando, G. J., Zhou, J., Tindle, R. W. and Frazer, I. H. (1993). Adjuvants Can Bias to Th1 or Th2 the Immune-Response to Hpv E7 Protein in Mice. -, -, 1993. BETHESDA: Wiley-Blackwell.

Adjuvants Can Bias to Th1 or Th2 the Immune-Response to Hpv E7 Protein in Mice

1993

Conference Publication

An Improved Immunoassay for the E7 Protein of Hpv16

Dunn, L. A., Tindle, R. W., Fernando, G. J. and Frazer, I. H. (1993). An Improved Immunoassay for the E7 Protein of Hpv16. -, -, 1993. BETHESDA: Wiley-Blackwell.

An Improved Immunoassay for the E7 Protein of Hpv16

1993

Journal Article

Expression of human papillomavirus type 16 E7 protein by recombinant baculovirus and use for the detection of E7 antibodies in sera from cervical carcinoma patients

Stacey, Simon N., Ghosh, Anna, Bartholomew, Jennifer S., Tindle, Robert W., Stern, Peter L., Mackett, Michael and Arrand, John R. (1993) Expression of human papillomavirus type 16 E7 protein by recombinant baculovirus and use for the detection of E7 antibodies in sera from cervical carcinoma patients. Journal of Medical Virology, 40 1: 14-21. doi:10.1002/jmv.1890400105

Expression of human papillomavirus type 16 E7 protein by recombinant baculovirus and use for the detection of E7 antibodies in sera from cervical carcinoma patients

1993

Conference Publication

Use of Recombinant Hepatitis-B Core Antigen Particles to Deliver Hpv16-E7 Immunogenic Signals

Tindle, R., Londono, P., Herd, K., Frazer, I. and Dougan, G. (1993). Use of Recombinant Hepatitis-B Core Antigen Particles to Deliver Hpv16-E7 Immunogenic Signals. -, -, -. Oxford, United Kingdom: John Wiley & Sons.

Use of Recombinant Hepatitis-B Core Antigen Particles to Deliver Hpv16-E7 Immunogenic Signals

1993

Conference Publication

A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer

Frazer, I. H., Lieppe, D., Lambert, P., Griep, A., Tindle, R. W. and Fernando, G. (1993). A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer. -, -, 1993. BETHESDA: FEDERATION AMER SOC EXP BIOL.

A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer

1992

Journal Article

Humoral immune response to the E7 open reading frame protein of human papillomavirus genotype 16 in subjects with anogenital papillomavirus infection and controls

Tindle, Robert W., Murray, Barbara, Herd, Karen, Kennedy, Lynn, O'Connor, Dan T., Fernando, Germain J. P. and Frazer, Ian H. (1992). Humoral immune response to the E7 open reading frame protein of human papillomavirus genotype 16 in subjects with anogenital papillomavirus infection and controls. Immunology and Infections Diseases, 2, 223-228.

Humoral immune response to the E7 open reading frame protein of human papillomavirus genotype 16 in subjects with anogenital papillomavirus infection and controls

1992

Journal Article

Isolation and characterization of human hematopoietic progenitor cells - an effective method for positive selection of CD34+ cells

SMELAND, EB, FUNDERUD, S, KVALHEIM, G, GAUDERNACK, G, RASMUSSEN, AM, RUSTEN, L, WANG, MY, TINDLE, RW, BLOMHOFF, HK and EGELAND, T (1992). Isolation and characterization of human hematopoietic progenitor cells - an effective method for positive selection of CD34+ cells. Leukemia, 6 (8), 845-852.

Isolation and characterization of human hematopoietic progenitor cells - an effective method for positive selection of CD34+ cells

1992

Journal Article

An Elisa Capture Assay for the E7 Transforming Proteins of Hpv16 and Hpv18

Selvey, L. A., Dunn, L. A., Murray, B., Tindle, R. W. and Frazer, I. H. (1992). An Elisa Capture Assay for the E7 Transforming Proteins of Hpv16 and Hpv18. Journal of Virological Methods, 37 (2), 119-128. doi: 10.1016/0166-0934(92)90039-G

An Elisa Capture Assay for the E7 Transforming Proteins of Hpv16 and Hpv18

1991

Journal Article

A 'public' T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes

Tindle, Robert W., Fernando, Germain J. P., Sterling, Jane C. and Frazer, Ian H. (1991). A 'public' T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes. Proceedings of the National Academy of Sciences of the United States of America, 88 (13), 5887-5891. doi: 10.1073/pnas.88.13.5887

A 'public' T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes

1990

Journal Article

Immunology of Anogenital Human Papillomavirus (Hpv) Infection

Tindle, R. W. and Frazer, I. H. (1990). Immunology of Anogenital Human Papillomavirus (Hpv) Infection. Australian & New Zealand Journal of Obstetrics & Gynaecology, 30 (4), 370-375. doi: 10.1111/j.1479-828X.1990.tb02033.x

Immunology of Anogenital Human Papillomavirus (Hpv) Infection

1990

Journal Article

Identification of B-Epitopes in the Human Papillomavirus-18 E7 Open Reading Frame Protein

Selvey, L. A., Tindle, R. W., Geysen, H. M., Haller, C. J., Smith, J. A. and Frazer, I. H. (1990). Identification of B-Epitopes in the Human Papillomavirus-18 E7 Open Reading Frame Protein. Journal of Immunology, 145 (9), 3105-3110.

Identification of B-Epitopes in the Human Papillomavirus-18 E7 Open Reading Frame Protein

Funding

Past funding

  • 2008
    SASVRC Study and Travel & Infrastucture
    Royal Children's Hospital Foundation
    Open grant
  • 2006 - 2008
    Development of Hepatitis B surface antigen as a generic vector for the delivery of foreign CTL epitopes.
    NHMRC Project Grant
    Open grant
  • 2006 - 2008
    Mechanisms of disease caused by human metapneumovirus and protection using a novel polytype vaccine
    University of Canberra
    Open grant
  • 2005 - 2006
    Co-administration of DNA encoding co-stimulatory molecules enhances the efficacy of immune response to foreign antigen
    NHMRC Project Grant
    Open grant
  • 2004 - 2006
    Development of a vaccine for human metapneumovirus-associated respiratory disease in children
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2005
    NHMRC_Equipment Grant _HLTH_CICR_Med SCD
    NHMRC Equipment Grant
    Open grant
  • 2004 - 2005
    Novel cancer vaccine delivery using recombinant Hepatitus B surface antigen VLP- and DNA vectors
    Queensland Cancer Fund
    Open grant
  • 2003 - 2004
    Novel polytope VLP vaccines for respiratory syncytial virus (RSV) infection in children
    Royal Children's Hospital Foundation
    Open grant
  • 2002
    Development of a HBV-specific carrier matrix to induce an immune response against quasispecies-like infectious agents
    NHMRC Project Grant
    Open grant
  • 2001 - 2003
    A Vaccine to Break Tolerance to Cervical Carcunoma Oncoprotein
    NHMRC Project Grant
    Open grant
  • 1999
    A 'polyepitope' DNA vaccine encoding CTL epitopes of HPV16 E7 restricted by multiple MHC class 1 haplotypes, protects against endogenous E7-expressing epithelial tumour: a cervical cancer DNA vaccine
    Cancer Bequest Fund
    Open grant
  • 1999 - 2000
    A recombinant Kunjin virus replicon vaccine will protect against the growth of a tumour expressing a tumour specific antigen
    Queensland Cancer Fund
    Open grant
  • 1999 - 2001
    Immunological Consequences of Epithelial Expression of a Viral Oncoprotein Associated with Cervical Carcinoma
    NHMRC Project Grant
    Open grant
  • 1998 - 1999
    The Body's Responses to Antigens in Skin in Adult Life
    Royal Children's Hospital Foundation
    Open grant
  • 1997
    Immunological consequences of neo-antigen presentation at the periphery
    UQ External Support Enabling Grant
    Open grant
  • 1996 - 1998
    Human papillomavirus (HPV) 16 E7 and squamous cell cancer: CTL and tumour protection elicited by oral recombinant Salmonella vaccines containing human CTL epitopes
    Queensland Cancer Fund
    Open grant
  • 1996 - 1997
    Immunity to peripheral 'non-self' antigen in mice transgenic for HPV transforming protein
    Queensland Cancer Fund
    Open grant
  • 1996
    Immunological consequences of neo-antigen presentation at the periphery
    NHMRC Project Grant
    Open grant
  • 1996 - 1997
    Human papillomavirus (HPV) 16 E7 and squamous cell cancer: CTL and tumour protection elicited by oral recombinant Salmonella vaccines containing human CTL epitopes
    Queensland Cancer Fund
    Open grant
  • 1995 - 1998
    The immunobiology of HPV-associated cancers
    United States National Institutes of Health
    Open grant

Supervision

Availability

Emeritus Professor Robert Tindle is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

Contact Emeritus Professor Robert Tindle directly for media enquiries about:

  • Human papillomavirus
  • Human respiratory viruses
  • Immune system and disease
  • Immunisation
  • Immunology
  • Papillomavirus
  • Respiratory viruses
  • T-cells
  • Vaccines
  • Viral immunology
  • Virology
  • Viruses

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