
Overview
Availability
- Emeritus Professor Robert Tindle is:
- Available for supervision
- Media expert
Qualifications
- Bachelor (Honours) of Science (Advanced), Institution to be confirmed
- Doctor of Philosophy, University College London
Research impacts
The CD34 stem cell has replaced marrow transplation in the treatment of leukaemias and other diseases throughout the world.
The tolerogenic effect of the HPV 16 E7 oncoprotein informs the design of therapeutic vaccines for human cervical cancer.
Works
Search Professor Robert Tindle’s works on UQ eSpace
1995
Journal Article
Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a production
Fernando, Germain J. P., Stenzel, Deborah J., Tindle, Robert W., Merza, Malik S., Morein, Bror and Frazer, Ian H. (1995). Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a production. Vaccine, 13 (15), 1460-1467. doi: 10.1016/0264-410X(95)00029-Z
1994
Journal Article
Cell-mediated immune responses to E7 peptides of human papillomavirus (HPV) type 16 are dependent on the HPV type infecting the cervix whereas serological reactivity is not type-specific
Kadish, Anna S., Romney, Seymour L., Ledwidge, Richard, Tindle, Robert, Fernando, Germain J. P., Zee, Sui Y., Van Ranst, Marc A. and Burk, Robert D. (1994). Cell-mediated immune responses to E7 peptides of human papillomavirus (HPV) type 16 are dependent on the HPV type infecting the cervix whereas serological reactivity is not type-specific. Journal of General Virology, 75 (9), 2277-2284. doi: 10.1099/0022-1317-75-9-2277
1994
Journal Article
Cell-Mediated Immune-Responses to E7 Peptides of Human Papillomavirus (hpv) Type-16 Are Dependent On the Hpv Type Infecting the Cervix Whereas Serological Reactivity Is Not Type-Specific
Kadish, A. S., Romney, S. L., Ledwidge, R., Tindle, R., Fernando, G. J. P., Zee, S. Y., Vanranst, M. A. and Burk, R. D. (1994). Cell-Mediated Immune-Responses to E7 Peptides of Human Papillomavirus (hpv) Type-16 Are Dependent On the Hpv Type Infecting the Cervix Whereas Serological Reactivity Is Not Type-Specific. Journal of General Virology, 75, 2277-2284. doi: 10.1099/0022-1317-75-9-2277
1994
Journal Article
Human Papillomavirus (Hpv) Type-18 E7 Protein Is a Short-Lived Steroid-Inducible Phosphoprotein in Hpv-Transformed Cell-Lines
Selvey, L. A., Dunn, L. A., Tindle, R. W., Park, D. S. and Frazer, I. H. (1994). Human Papillomavirus (Hpv) Type-18 E7 Protein Is a Short-Lived Steroid-Inducible Phosphoprotein in Hpv-Transformed Cell-Lines. Journal of General Virology, 75 (7), 1647-1653. doi: 10.1099/0022-1317-75-7-1647
1994
Conference Publication
A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer
Frazer, I. H., Lieppe, D., Lambert, P., Griep, A., Dunn, L., Tindle, R. W. and Fernando, G. (1994). A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer. Keystone Symposia on Molecular & Cellular Biology, Taos, New Mexico , 13 - 20 February 1994. NEW YORK: Wiley-Blackwell.
1994
Conference Publication
Use of a Double Aro Salmonella Mutant to Stably Express Hbv16 E7 Protein Epitopes Carried by the Hbv Core Antigen
Londono, P., Chatfield, S., Tindle, R., Frazer, I. and Dougan, G. (1994). Use of a Double Aro Salmonella Mutant to Stably Express Hbv16 E7 Protein Epitopes Carried by the Hbv Core Antigen. In: Journal of Cellular Biochemistry. Keystone Symposia on Molecular & Cellular Biology, Taos, New Mexico , (232-232). 13 - 20 February 1994.
1994
Journal Article
Immune response to human papillomaviruses and the prospects for human papillomavirus-specific immunisation
Tindle, R. W. and Frazer, I. H. (1994). Immune response to human papillomaviruses and the prospects for human papillomavirus-specific immunisation. Current Topics in Microbiology and Immunology, 186, 217-253. doi: 10.1007/978-3-642-78487-3_12
1994
Conference Publication
Small Synthetic Peptides as Vaccines - a Model Peptide Iscom Construct From Cancer-Associated Human Papillomavirus
Fernando, G. J. P., Tindle, R. W., Frazer, I. H., Stenzel, D. J., Merza, M. S. and Morein, B. (1994). Small Synthetic Peptides as Vaccines - a Model Peptide Iscom Construct From Cancer-Associated Human Papillomavirus. 11th Annual Meeting on Modern Approaches to New Vaccines, Cold Spring Harbor, NY United States, September 1993. PLAINVIEW: COLD SPRING HARBOR LABORATORY PRESS.
1994
Journal Article
Chimeric hepatitis B core antigen particles containing B- and Th-epitopes of human papillomavirus type 16 E7 protein induce specific antibody and T-helper responses in immunised mice
Tindle, Robert W., Herd, Karen, Londoño, Patricia, Fernando, Germain J. P., Chatfield, Steven N., Malcolm, Karen and Dougan, Gordon (1994). Chimeric hepatitis B core antigen particles containing B- and Th-epitopes of human papillomavirus type 16 E7 protein induce specific antibody and T-helper responses in immunised mice. Virology, 200 (2), 547-557. doi: 10.1006/viro.1994.1217
1993
Conference Publication
Adjuvants Can Bias to Th1 or Th2 the Immune-Response to Hpv E7 Protein in Mice
Fernando, G. J., Zhou, J., Tindle, R. W. and Frazer, I. H. (1993). Adjuvants Can Bias to Th1 or Th2 the Immune-Response to Hpv E7 Protein in Mice. -, -, 1993. BETHESDA: Wiley-Blackwell.
1993
Conference Publication
An Improved Immunoassay for the E7 Protein of Hpv16
Dunn, L. A., Tindle, R. W., Fernando, G. J. and Frazer, I. H. (1993). An Improved Immunoassay for the E7 Protein of Hpv16. -, -, 1993. BETHESDA: Wiley-Blackwell.
1993
Journal Article
Expression of human papillomavirus type 16 E7 protein by recombinant baculovirus and use for the detection of E7 antibodies in sera from cervical carcinoma patients
Stacey, Simon N., Ghosh, Anna, Bartholomew, Jennifer S., Tindle, Robert W., Stern, Peter L., Mackett, Michael and Arrand, John R. (1993) Expression of human papillomavirus type 16 E7 protein by recombinant baculovirus and use for the detection of E7 antibodies in sera from cervical carcinoma patients. Journal of Medical Virology, 40 1: 14-21. doi:10.1002/jmv.1890400105
1993
Conference Publication
Use of Recombinant Hepatitis-B Core Antigen Particles to Deliver Hpv16-E7 Immunogenic Signals
Tindle, R., Londono, P., Herd, K., Frazer, I. and Dougan, G. (1993). Use of Recombinant Hepatitis-B Core Antigen Particles to Deliver Hpv16-E7 Immunogenic Signals. -, -, -. Oxford, United Kingdom: John Wiley & Sons.
1993
Conference Publication
A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer
Frazer, I. H., Lieppe, D., Lambert, P., Griep, A., Tindle, R. W. and Fernando, G. (1993). A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer. -, -, 1993. BETHESDA: FEDERATION AMER SOC EXP BIOL.
1992
Journal Article
Humoral immune response to the E7 open reading frame protein of human papillomavirus genotype 16 in subjects with anogenital papillomavirus infection and controls
Tindle, Robert W., Murray, Barbara, Herd, Karen, Kennedy, Lynn, O'Connor, Dan T., Fernando, Germain J. P. and Frazer, Ian H. (1992). Humoral immune response to the E7 open reading frame protein of human papillomavirus genotype 16 in subjects with anogenital papillomavirus infection and controls. Immunology and Infections Diseases, 2, 223-228.
1992
Journal Article
Isolation and characterization of human hematopoietic progenitor cells - an effective method for positive selection of CD34+ cells
SMELAND, EB, FUNDERUD, S, KVALHEIM, G, GAUDERNACK, G, RASMUSSEN, AM, RUSTEN, L, WANG, MY, TINDLE, RW, BLOMHOFF, HK and EGELAND, T (1992). Isolation and characterization of human hematopoietic progenitor cells - an effective method for positive selection of CD34+ cells. Leukemia, 6 (8), 845-852.
1992
Journal Article
An Elisa Capture Assay for the E7 Transforming Proteins of Hpv16 and Hpv18
Selvey, L. A., Dunn, L. A., Murray, B., Tindle, R. W. and Frazer, I. H. (1992). An Elisa Capture Assay for the E7 Transforming Proteins of Hpv16 and Hpv18. Journal of Virological Methods, 37 (2), 119-128. doi: 10.1016/0166-0934(92)90039-G
1991
Journal Article
A 'public' T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes
Tindle, Robert W., Fernando, Germain J. P., Sterling, Jane C. and Frazer, Ian H. (1991). A 'public' T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes. Proceedings of the National Academy of Sciences of the United States of America, 88 (13), 5887-5891. doi: 10.1073/pnas.88.13.5887
1990
Journal Article
Immunology of Anogenital Human Papillomavirus (Hpv) Infection
Tindle, R. W. and Frazer, I. H. (1990). Immunology of Anogenital Human Papillomavirus (Hpv) Infection. Australian & New Zealand Journal of Obstetrics & Gynaecology, 30 (4), 370-375. doi: 10.1111/j.1479-828X.1990.tb02033.x
1990
Journal Article
Identification of B-Epitopes in the Human Papillomavirus-18 E7 Open Reading Frame Protein
Selvey, L. A., Tindle, R. W., Geysen, H. M., Haller, C. J., Smith, J. A. and Frazer, I. H. (1990). Identification of B-Epitopes in the Human Papillomavirus-18 E7 Open Reading Frame Protein. Journal of Immunology, 145 (9), 3105-3110.
Funding
Supervision
Availability
- Emeritus Professor Robert Tindle is:
- Available for supervision
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Supervision history
Completed supervision
-
2010
Doctor Philosophy
Hepatitis B Surface Antigen-based Vaccines for Human Neoplastic Disease
Principal Advisor
-
2007
Doctor Philosophy
THE USE OF HEPATITIS B SURFACE ANTIGEN-SMALL AS A VACCINE SYSTEM FOR DELIVERY OF FOREIGN CTL EPITOPES
Principal Advisor
Media
Enquiries
Contact Emeritus Professor Robert Tindle directly for media enquiries about:
- Human papillomavirus
- Human respiratory viruses
- Immune system and disease
- Immunisation
- Immunology
- Papillomavirus
- Respiratory viruses
- T-cells
- Vaccines
- Viral immunology
- Virology
- Viruses
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