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Emeritus Professor Robert Tindle
Emeritus Professor

Robert Tindle

Email: 

Overview

Availability

Emeritus Professor Robert Tindle is:
Available for supervision
Media expert

Qualifications

  • Bachelor (Honours) of Science (Advanced), Institution to be confirmed
  • Doctor of Philosophy, University College London

Research impacts

The CD34 stem cell has replaced marrow transplation in the treatment of leukaemias and other diseases throughout the world.

The tolerogenic effect of the HPV 16 E7 oncoprotein informs the design of therapeutic vaccines for human cervical cancer.

Works

Search Professor Robert Tindle’s works on UQ eSpace

104 works between 1975 and 2024

41 - 60 of 104 works

1999

Journal Article

T-Helper epitopes identified within the E6 transforming protein of cervical cancer-associated human papillomavirus type 16

Azoury-Ziadeh, Rania, Herd, Karen, Fernando, Germain J. P., Frazer, Ian H. and Tindle, Robert W. (1999). T-Helper epitopes identified within the E6 transforming protein of cervical cancer-associated human papillomavirus type 16. Viral Immunology, 12 (4), 297-312. doi: 10.1089/vim.1999.12.297

T-Helper epitopes identified within the E6 transforming protein of cervical cancer-associated human papillomavirus type 16

1999

Book Chapter

Cell mediated immunity to papillomaviruses

Frazer, I. H. and Tindle, R. (1999). Cell mediated immunity to papillomaviruses. Current research on papillomaviruses. (pp. 151-164) edited by Charles Lacey. Leeds, England: Leeds University Press.

Cell mediated immunity to papillomaviruses

1999

Book Chapter

Safety and Immunogenicity of HPV16 E7/Algammulin

Frazer, I. H., Tindle, R. W., Fernando, G. J., Malcolm, K. M., Herd, K. A., McFadyen, S. M., Cooper, P. D. and Ward, B. G. (1999). Safety and Immunogenicity of HPV16 E7/Algammulin. Vaccines for Human Papillomavirus Infection and Anogenital Disease. (pp. 91-104) edited by R. W. Tindle. Austin, USA: R.G. Landes Company.

Safety and Immunogenicity of HPV16 E7/Algammulin

1999

Book

Vaccines for Human Papillomavirus Infection and Anogenital Disease

Vaccines for Human Papillomavirus Infection and Anogenital Disease. Edited by Tindle, R. W. Richmond, TX United States: R. G. Landes Company, 1999.

Vaccines for Human Papillomavirus Infection and Anogenital Disease

1998

Journal Article

Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes

Frazer, Ian H., Fernando, Germain J. P., Fowler, Nina, Leggatt, Graham R., Lambert, Paul F., Liem, Amy, Malcolm, Karen and Tindle, Robert W. (1998). Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes. European Journal of Immunology, 28 (9), 2791-2800. doi: 10.1002/(SICI)1521-4141(199809)28:093.0.CO;2-B

Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes

1998

Journal Article

Th2-type CD4(+) cells neither enhance nor suppress antitumor CTL activity in a mouse tumor model

Fernando, Germain J. P., Stewart, Trina J., Tindle, Robert W. and Frazer, Ian H. (1998). Th2-type CD4(+) cells neither enhance nor suppress antitumor CTL activity in a mouse tumor model. Journal of Immunology, 161 (5), 2421-2427.

Th2-type CD4(+) cells neither enhance nor suppress antitumor CTL activity in a mouse tumor model

1998

Journal Article

Mice expressing the E7 oncogene of HPV16 in epithelium show central tolerance, and evidence of peripheral anergising tolerance, to E7-encoded cytotoxic T-lymphocyte epitopes

Doan, Tracy, Chambers, Melita, Street, Michael, Fernando, Germain J. P., Herd, Karen, Lambert, Paul and Tindle, Robert (1998). Mice expressing the E7 oncogene of HPV16 in epithelium show central tolerance, and evidence of peripheral anergising tolerance, to E7-encoded cytotoxic T-lymphocyte epitopes. Virology, 244 (2), 352-364. doi: 10.1006/viro.1998.9128

Mice expressing the E7 oncogene of HPV16 in epithelium show central tolerance, and evidence of peripheral anergising tolerance, to E7-encoded cytotoxic T-lymphocyte epitopes

1998

Journal Article

Vaccine-induced Th1-type responses are dominant over Th2-type responses in the short term whereas pre-existing Th2 responses are dominant in the longer term

Fernando, G. J. P., Stewart, T. J., Tindle, R. W. and Frazer, I. H. (1998). Vaccine-induced Th1-type responses are dominant over Th2-type responses in the short term whereas pre-existing Th2 responses are dominant in the longer term. Scandinavian Journal of Immunology, 47 (5), 459-465. doi: 10.1046/j.1365-3083.1998.00327.x

Vaccine-induced Th1-type responses are dominant over Th2-type responses in the short term whereas pre-existing Th2 responses are dominant in the longer term

1997

Journal Article

Immunomanipulative strategies for the control of human papillomavirus associated cervical disease

Tindle, Robert W. (1997). Immunomanipulative strategies for the control of human papillomavirus associated cervical disease. Immunologic Research, 16 (4), 387-400. doi: 10.1007/BF02786401

Immunomanipulative strategies for the control of human papillomavirus associated cervical disease

1997

Journal Article

Presentation of the HPV16E7 protein by skin grafts is insufficient to allow graft rejection in an E7-primed animal

Dunn, Linda A., Evander, Magnus, Tindle, Robert W., Bulloch, Anne Louise, de Kluyver, Rachel L., Fernando, Germain J. P., Lambert, Paul F. and Frazer, Ian H. (1997). Presentation of the HPV16E7 protein by skin grafts is insufficient to allow graft rejection in an E7-primed animal. Virology, 235 (1), 94-103. doi: 10.1006/viro.1997.8650

Presentation of the HPV16E7 protein by skin grafts is insufficient to allow graft rejection in an E7-primed animal

1997

Journal Article

E7 oncoprotein of human papillomavirus type 16 expressed constitutively in the epidermis has no effect on E7-specific B- or Th-repertoires or on the immune response induced or sustained after immunization with E7 protein

Herd, K., Fernando, G. J. P., Dunn, L. A., Frazer, I. H., Lambert, P. and Tindle, R. W. (1997). E7 oncoprotein of human papillomavirus type 16 expressed constitutively in the epidermis has no effect on E7-specific B- or Th-repertoires or on the immune response induced or sustained after immunization with E7 protein. Virology, 231 (1), 155-165. doi: 10.1006/viro.1997.8491

E7 oncoprotein of human papillomavirus type 16 expressed constitutively in the epidermis has no effect on E7-specific B- or Th-repertoires or on the immune response induced or sustained after immunization with E7 protein

1996

Journal Article

Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein

Zerfass-Thome, Karin, Zwerschke, Werner, Mannhardt, Boris, Tindle, Robert, Botz, Jürgen W. and Jansen-Dürr, Pidder (1996). Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein. Oncogene, 13 (11), 2323-2330.

Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein

1996

Journal Article

Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen

Londono, L. Patricia, Chatfield, Steven, Tindle, Robert W., Herd, Karen, Gao, Xiao-Ming, Frazer, Ian and Dougan, Gordon (1996). Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen. Vaccine, 14 (6), 545-552. doi: 10.1016/0264-410X(95)00216-N

Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen

1996

Journal Article

Human papillomavirus vaccines for cervical cancer

Tindle, Robert W (1996). Human papillomavirus vaccines for cervical cancer. Current Opinion in Immunology, 8 (5), 643-650. doi: 10.1016/S0952-7915(96)80080-X

Human papillomavirus vaccines for cervical cancer

1995

Journal Article

Section review: Biologicals & immunologicals: Human papillomavirus infection, genital warts and cervical cancer: Prospects for prophylactic and therapeutic vaccines

Tindle, Robert W. and Frazer, Ian H. (1995). Section review: Biologicals & immunologicals: Human papillomavirus infection, genital warts and cervical cancer: Prospects for prophylactic and therapeutic vaccines. Expert Opinion on Investigational Drugs, 4 (9), 783-797. doi: 10.1517/13543784.4.9.783

Section review: Biologicals & immunologicals: Human papillomavirus infection, genital warts and cervical cancer: Prospects for prophylactic and therapeutic vaccines

1995

Journal Article

Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin disease

Frazer, I. H., Leippe, D. M., Dunn, L. A., Liem, A., Tindle, R. W., Fernando, G. J. P., Phelps, W. C. and Lambert, P. F. (1995). Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin disease. Cancer Research, 55 (12), 2635-2639.

Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin disease

1995

Journal Article

T-helper epitopes of the E7 transforming protein of cervical-cancer associated human papillomavirus type-18 (hpv18)

Fernando, G.J.P., Tindle, R.W and Frazer, I.H. (1995). T-helper epitopes of the E7 transforming protein of cervical-cancer associated human papillomavirus type-18 (hpv18). Virus Research, 36 (1), 1-13. doi: 10.1016/0168-1702(94)00101-H

T-helper epitopes of the E7 transforming protein of cervical-cancer associated human papillomavirus type-18 (hpv18)

1995

Journal Article

A vaccine conjugate of 'ISCAR' immunocarrier and peptide epitopes of the E7 cervical cancer-associated protein of human papillomavirus type 16 elicits specific Th1- and Th2-type responses in immunized mice in the absence of oil-based adjuvants

Tindle, R. W., Croft, S., Herd, K., Malcolm, K., Geczy, A. F., Stewart, T. and Fernando, G. J. (1995). A vaccine conjugate of 'ISCAR' immunocarrier and peptide epitopes of the E7 cervical cancer-associated protein of human papillomavirus type 16 elicits specific Th1- and Th2-type responses in immunized mice in the absence of oil-based adjuvants. Clinical and Experimental Immunology, 101 (2), 265-271. doi: 10.1111/j.1365-2249.1995.tb08349.x

A vaccine conjugate of 'ISCAR' immunocarrier and peptide epitopes of the E7 cervical cancer-associated protein of human papillomavirus type 16 elicits specific Th1- and Th2-type responses in immunized mice in the absence of oil-based adjuvants

1995

Journal Article

Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a production

Fernando, Germain J. P., Stenzel, Deborah J., Tindle, Robert W., Merza, Malik S., Morein, Bror and Frazer, Ian H. (1995). Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a production. Vaccine, 13 (15), 1460-1467. doi: 10.1016/0264-410X(95)00029-Z

Peptide polymerisation facilitates incorporation into ISCOMs and increases antigen-specific IgG2a production

1995

Conference Publication

Hpv16 E7 Transgenic Skin Is Not Rejected in E7 Immunized Mice

Frazer, I. H., Dunn, L. A., Fernando, G. J., Tindle, R. W., Leippe, D. M. and Lambert, P. F. (1995). Hpv16 E7 Transgenic Skin Is Not Rejected in E7 Immunized Mice. Keystone Symposia on Molecular & Cellular Biology, Keystone, CO United States, 16-23 January 1995 . NEW YORK: Wiley-Blackwell.

Hpv16 E7 Transgenic Skin Is Not Rejected in E7 Immunized Mice

Funding

Past funding

  • 2008
    SASVRC Study and Travel & Infrastucture
    Royal Children's Hospital Foundation
    Open grant
  • 2006 - 2008
    Development of Hepatitis B surface antigen as a generic vector for the delivery of foreign CTL epitopes.
    NHMRC Project Grant
    Open grant
  • 2006 - 2008
    Mechanisms of disease caused by human metapneumovirus and protection using a novel polytype vaccine
    University of Canberra
    Open grant
  • 2005 - 2006
    Co-administration of DNA encoding co-stimulatory molecules enhances the efficacy of immune response to foreign antigen
    NHMRC Project Grant
    Open grant
  • 2004 - 2006
    Development of a vaccine for human metapneumovirus-associated respiratory disease in children
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2005
    NHMRC_Equipment Grant _HLTH_CICR_Med SCD
    NHMRC Equipment Grant
    Open grant
  • 2004 - 2005
    Novel cancer vaccine delivery using recombinant Hepatitus B surface antigen VLP- and DNA vectors
    Queensland Cancer Fund
    Open grant
  • 2003 - 2004
    Novel polytope VLP vaccines for respiratory syncytial virus (RSV) infection in children
    Royal Children's Hospital Foundation
    Open grant
  • 2002
    Development of a HBV-specific carrier matrix to induce an immune response against quasispecies-like infectious agents
    NHMRC Project Grant
    Open grant
  • 2001 - 2003
    A Vaccine to Break Tolerance to Cervical Carcunoma Oncoprotein
    NHMRC Project Grant
    Open grant
  • 2000 - 2002
    A polyepitope HPV 16 E7 DNA vaccine restricted through multiple class 1 haplotypes protects against E7-expressing tumour
    NHMRC Project Grant
    Open grant
  • 1999
    A 'polyepitope' DNA vaccine encoding CTL epitopes of HPV16 E7 restricted by multiple MHC class 1 haplotypes, protects against endogenous E7-expressing epithelial tumour: a cervical cancer DNA vaccine
    Cancer Bequest Fund
    Open grant
  • 1999 - 2000
    A recombinant Kunjin virus replicon vaccine will protect against the growth of a tumour expressing a tumour specific antigen
    Queensland Cancer Fund
    Open grant
  • 1999 - 2001
    Immunological Consequences of Epithelial Expression of a Viral Oncoprotein Associated with Cervical Carcinoma
    NHMRC Project Grant
    Open grant
  • 1998 - 1999
    The Body's Responses to Antigens in Skin in Adult Life
    Royal Children's Hospital Foundation
    Open grant
  • 1998 - 1999
    A novel recombinant Hepatitis D virus-like particle vaccine elicits human MHC calss 1 restricted CTL responses, which protect against establishment and growth of tumours expressing the E7 oncoprotein
    Queensland Cancer Fund
    Open grant
  • 1997
    Immunological consequences of neo-antigen presentation at the periphery
    UQ External Support Enabling Grant
    Open grant
  • 1997
    Neo-antigen presentation at the periphery
    Royal Children's Hospital Foundation
    Open grant
  • 1996 - 1998
    Human papillomavirus (HPV) 16 E7 and squamous cell cancer: CTL and tumour protection elicited by oral recombinant Salmonella vaccines containing human CTL epitopes
    Queensland Cancer Fund
    Open grant
  • 1996 - 1997
    Immunity to peripheral 'non-self' antigen in mice transgenic for HPV transforming protein
    Queensland Cancer Fund
    Open grant
  • 1996
    Immunological consequences of neo-antigen presentation at the periphery
    NHMRC Project Grant
    Open grant
  • 1996 - 1999
    Viral research
    Sir Albert Sakzewski Virus Research Centre
    Open grant
  • 1996 - 1997
    Human papillomavirus (HPV) 16 E7 and squamous cell cancer: CTL and tumour protection elicited by oral recombinant Salmonella vaccines containing human CTL epitopes
    Queensland Cancer Fund
    Open grant
  • 1996
    Immunological consequences of neo-antigen presentation at the periphery
    NHMRC Project Grant
    Open grant
  • 1995 - 1998
    The immunobiology of HPV-associated cancers
    United States National Institutes of Health
    Open grant
  • 1995 - 1996
    Immunity to peripheral 'non-self' antigen in mice transgenic for HPV transforming protein
    Queensland Cancer Fund
    Open grant

Supervision

Availability

Emeritus Professor Robert Tindle is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

Contact Emeritus Professor Robert Tindle directly for media enquiries about:

  • Human papillomavirus
  • Human respiratory viruses
  • Immune system and disease
  • Immunisation
  • Immunology
  • Papillomavirus
  • Respiratory viruses
  • T-cells
  • Vaccines
  • Viral immunology
  • Virology
  • Viruses

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