Emeritus Professor Robert Tindle
Emeritus Professor

Robert Tindle

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Availability

Emeritus Professor Robert Tindle is:
Available for supervision
Media expert

Qualifications

  • Bachelor (Honours) of Science (Advanced), Institution to be confirmed
  • Doctor of Philosophy, University College London

Research impacts

The CD34 stem cell has replaced marrow transplation in the treatment of leukaemias and other diseases throughout the world.

The tolerogenic effect of the HPV 16 E7 oncoprotein informs the design of therapeutic vaccines for human cervical cancer.

Search Professor Robert Tindle’s works on UQ eSpace

104 works between 1975 and 2024
All (104) Journal Article (85) Book Chapter (5) Conference Publication (9) Book (2) Other Outputs (3)

21 - 40 of 104 works

2004

Journal Article

Recombinant Kunjin virus replicon vaccines induce protective T-cell immunity against human papillomavirus 16 E7-expressing tumour

Herd, Karen A., Harvey, Tracey, Khromykh, Alexander A. and Tindle, Robert W. (2004). Recombinant Kunjin virus replicon vaccines induce protective T-cell immunity against human papillomavirus 16 E7-expressing tumour. Virology, 319 (2), 237-248. doi: 10.1016/j.virol.2003.10.032

Recombinant Kunjin virus replicon vaccines induce protective T-cell immunity against human papillomavirus 16 E7-expressing tumour

2003

Journal Article

Enhanced effector and memory CTL responses generated by incorporation of receptor activator of NF-kappa B(RANK)/RANK ligand costimulatory molecules into dendritic cell immunogens expressing a human tumor-specific antigen

Wiethe, C., Dittmar, K., Doan, T., Lindenmaier, W. and Tindle, R. (2003). Enhanced effector and memory CTL responses generated by incorporation of receptor activator of NF-kappa B(RANK)/RANK ligand costimulatory molecules into dendritic cell immunogens expressing a human tumor-specific antigen. Journal of Immunology, 171 (8), 4121-4130. doi: 10.4049/jimmunol.171.8.4121

Enhanced effector and memory CTL responses generated by incorporation of receptor activator of NF-kappa B(RANK)/RANK ligand costimulatory molecules into dendritic cell immunogens expressing a human tumor-specific antigen

2003

Journal Article

Generation of CTL responses using Kunjin replicon RNA

Ward, Scott M., Tindle, Robert W., Khromykh, Alexander A. and Gowans, Eric J. (2003). Generation of CTL responses using Kunjin replicon RNA. Immunology And Cell Biology, 81 (1), 73-78. doi: 10.1046/j.0818-9641.2002.01137.x

Generation of CTL responses using Kunjin replicon RNA

2003

Journal Article

Paucity of functional CTL epitopes in the E7 oncoprotein of cervical cancer associated human papillomavirus type 16

Khammanivong, Vithagna, Liu, Xiao Song, Liu, Wen Jun, Rodda, Stuart J., Leggatt, Graham R., Tindle, Robert W., Frazer, Ian H. and Fernando, Germain J. P. (2003). Paucity of functional CTL epitopes in the E7 oncoprotein of cervical cancer associated human papillomavirus type 16. Immunology and Cell Biology, 81 (1), 1-7. doi: 10.1046/j.1440-1711.2003.01130.x

Paucity of functional CTL epitopes in the E7 oncoprotein of cervical cancer associated human papillomavirus type 16

2003

Journal Article

Immunogenicity of recombinant HBsAg/HCV particles in mice pre-immunised with hepatitis B virus-specific vaccine

Netter, H.J., Woo, W.P., Tindle, R., Macfarlan, R.I. and Gowans, E.J. (2003). Immunogenicity of recombinant HBsAg/HCV particles in mice pre-immunised with hepatitis B virus-specific vaccine. Vaccine, 21 (21-22), 2692-2697. doi: 10.1016/S0264-410X(03)00182-8

Immunogenicity of recombinant HBsAg/HCV particles in mice pre-immunised with hepatitis B virus-specific vaccine

2003

Journal Article

Provision of 4-1BB ligand enhances effector and memory CTL responses generated by immunization with dendritic cells expressing a human tumor-associated antigen

Wiethe, C, Dittmar, K, Doan, T, Lindenmaier, W and Tindle, R (2003). Provision of 4-1BB ligand enhances effector and memory CTL responses generated by immunization with dendritic cells expressing a human tumor-associated antigen. Journal of Immunology, 170 (6), 2912-2922. doi: 10.4049/jimmunol.170.6.2912

Provision of 4-1BB ligand enhances effector and memory CTL responses generated by immunization with dendritic cells expressing a human tumor-associated antigen

2002

Journal Article

Limitations of HLA-transgenic mice in presentation of HLA-restricted cytotoxic T-cell epitopes from endogenously processed human papillomavirus type 16 E7 protein

Street, MD, Doan, T, Herd, KA and Tindle, RW (2002). Limitations of HLA-transgenic mice in presentation of HLA-restricted cytotoxic T-cell epitopes from endogenously processed human papillomavirus type 16 E7 protein. Immunology, 106 (4), 526-536. doi: 10.1046/j.1365-2567.2002.01442.x

Limitations of HLA-transgenic mice in presentation of HLA-restricted cytotoxic T-cell epitopes from endogenously processed human papillomavirus type 16 E7 protein

2002

Journal Article

Immune evasion in human papillomavirus-associated cervical cancer

Tindle, R. W. (2002). Immune evasion in human papillomavirus-associated cervical cancer. Nature Reviews Cancer, 2 (1), 59-65. doi: 10.1038/nrc700

Immune evasion in human papillomavirus-associated cervical cancer

2001

Journal Article

Nonspecific down-regulation of CD8+ T-Cell responses in mice expressing human Papillomavirus Type 16 E7 oncoprotein from the keratin-14 promoter

Tindle, Robert W., Herd, Karen A., Doan, Tracy, Bryson, Greg, Leggatt, Graham R., Lambert, Paul, Ian H. Frazer, and Street, Michael D. (2001). Nonspecific down-regulation of CD8+ T-Cell responses in mice expressing human Papillomavirus Type 16 E7 oncoprotein from the keratin-14 promoter. Journal of Virology, 75 (13), 5985-5997. doi: 10.1128/JVI.75.13.5985-5997.2001

Nonspecific down-regulation of CD8+ T-Cell responses in mice expressing human Papillomavirus Type 16 E7 oncoprotein from the keratin-14 promoter

2001

Journal Article

Antigenicity and immunogenicity of novel chimeric hepatitis B surface antigen particles with exposed hepatitis C virus epitopes

Netter, Hans J., MacNaughton, Thomas B., Woo, Wai-Ping, Tindle, Robert and Gowans, Eric J. (2001). Antigenicity and immunogenicity of novel chimeric hepatitis B surface antigen particles with exposed hepatitis C virus epitopes. Journal of Virology, 75 (5), 2130-2141. doi: 10.1128/JVI.75.5.2130-2141.2001

Antigenicity and immunogenicity of novel chimeric hepatitis B surface antigen particles with exposed hepatitis C virus epitopes

2001

Other Outputs

Subunit papilloma virus vaccine and peptides for use therein

Tindle, Robert, Fernando, Germain and Frazer, Ian (2001). Subunit papilloma virus vaccine and peptides for use therein. US6183745B1.

Subunit papilloma virus vaccine and peptides for use therein

2001

Journal Article

Low level expression of human papillomavirus type 16 (HPV16) E6 in squamous epithelium does not elicit E6 specific B- or T-helper immunological responses, or influence the outcome of immunisation with E6 protein

Azoury-Ziadeh, R, Herd, K, Fernando, GJP, Lambert, P, Frazer, IH and Tindle, RW (2001). Low level expression of human papillomavirus type 16 (HPV16) E6 in squamous epithelium does not elicit E6 specific B- or T-helper immunological responses, or influence the outcome of immunisation with E6 protein. Virus Research, 73 (2), 189-199. doi: 10.1016/S0168-1702(00)00241-0

Low level expression of human papillomavirus type 16 (HPV16) E6 in squamous epithelium does not elicit E6 specific B- or T-helper immunological responses, or influence the outcome of immunisation with E6 protein

2001

Journal Article

Peripheral T-Cell tolerance defined through transgenic mouse studies

Tindle, RW (2001). Peripheral T-Cell tolerance defined through transgenic mouse studies. Autoimmunity, 33 (2), 135-149. doi: 10.3109/08916930108995998

Peripheral T-Cell tolerance defined through transgenic mouse studies

2000

Journal Article

Peripheral tolerance to human papillomavirus E7 oncoprotein occurs by cross-tolerization, is largely Th-2-independent, and is broken by dendritic cell immunization

Doan, Tracy, Herd, Karen A., Lambert, Paul F., Fernando, Germain J. P., Street, Michael D. and Tindle, Robert W. (2000). Peripheral tolerance to human papillomavirus E7 oncoprotein occurs by cross-tolerization, is largely Th-2-independent, and is broken by dendritic cell immunization. Cancer Research, 60 (11), 2810-2815.

Peripheral tolerance to human papillomavirus E7 oncoprotein occurs by cross-tolerization, is largely Th-2-independent, and is broken by dendritic cell immunization

1999

Journal Article

Capture ELISA and in vitro cell binding assay for the detection of antibodies to human papillomavirus type 6b virus-like particles in patients with anogenital warts

Peng, Shiwen, Qi, Yingmei, Christensen, Neil, Hengst, Kylie, Kennedy, Lynn, Frazer, Ian H. and Tindle, Robert W. (1999). Capture ELISA and in vitro cell binding assay for the detection of antibodies to human papillomavirus type 6b virus-like particles in patients with anogenital warts. Pathology, 31 (4), 418-422. doi: 10.1080/003130299104846

Capture ELISA and in vitro cell binding assay for the detection of antibodies to human papillomavirus type 6b virus-like particles in patients with anogenital warts

1999

Journal Article

Differences in the effectiveness of delivery of B- and CTL-epitopes incorporated into the Hepatitis B core antigen (HBcAg) c/e1-region

Street, M., Herd, K., Londono, P., Doan, T., Dougan, G., Kast, W. M. and Tindle, R. W. (1999). Differences in the effectiveness of delivery of B- and CTL-epitopes incorporated into the Hepatitis B core antigen (HBcAg) c/e1-region. Archives of Virology, 144 (7), 1323-1343. doi: 10.1007/s007050050590

Differences in the effectiveness of delivery of B- and CTL-epitopes incorporated into the Hepatitis B core antigen (HBcAg) c/e1-region

1999

Journal Article

Human papillomavirus type 16 E7 oncoprotein expressed in peripheral epithelium tolerizes E7-directed cytotoxic T-lymphocyte precursors restricted through human (and mouse) major histocompatibility complex class I alleles

Doan, Tracy, Herd, Karen, Street, Michael, Bryson, Gregory, Fernando, Germain, Lambert, Paul and Tindle, Robert (1999). Human papillomavirus type 16 E7 oncoprotein expressed in peripheral epithelium tolerizes E7-directed cytotoxic T-lymphocyte precursors restricted through human (and mouse) major histocompatibility complex class I alleles. Journal of Virology, 73 (7), 6166-6170. doi: 10.1128/jvi.73.7.6166-6170.1999

Human papillomavirus type 16 E7 oncoprotein expressed in peripheral epithelium tolerizes E7-directed cytotoxic T-lymphocyte precursors restricted through human (and mouse) major histocompatibility complex class I alleles

1999

Journal Article

Potential strategies utilised by papillomavirus to evade host immunity

Frazer, Ian H., Thomas, Ranjeny, Zhou, Jian A., Leggatt, Graham R., Dunn, Linda, Mcmillan, Nigel A. J., Tindle, Robert W., Filgueira, Luis, Manders, Peter, Barnard, Paula and Sharkey, Michael (1999). Potential strategies utilised by papillomavirus to evade host immunity. Immunological Reviews, 168 (1), 131-142. doi: 10.1111/j.1600-065X.1999.tb01288.x

Potential strategies utilised by papillomavirus to evade host immunity

1999

Book Chapter

Immunomodulation of HPV infection and disease

Tindle, R. W. (1999). Immunomodulation of HPV infection and disease. Vaccines for Human Papillomavirus Infection and Anogenital Disease. (pp. 1-12) edited by Robert W. Tindle. Texas, USA: R. G. Landes Company.

Immunomodulation of HPV infection and disease

1999

Journal Article

Vaccines for human papillomavirus-associated anogenital disease and cervical cancer: Practical and theoretical approaches

Street, M. D. and Tindle, R. W. (1999). Vaccines for human papillomavirus-associated anogenital disease and cervical cancer: Practical and theoretical approaches. Expert Opinion in Investigational Drugs, 8 (6), 1-16.

Vaccines for human papillomavirus-associated anogenital disease and cervical cancer: Practical and theoretical approaches

Past funding

  • 2008
    SASVRC Study and Travel & Infrastucture
    Royal Children's Hospital Foundation
    Open grant
  • 2006 - 2008
    Development of Hepatitis B surface antigen as a generic vector for the delivery of foreign CTL epitopes.
    NHMRC Project Grant
    Open grant
  • 2006 - 2008
    Mechanisms of disease caused by human metapneumovirus and protection using a novel polytype vaccine
    University of Canberra
    Open grant
  • 2005 - 2006
    Co-administration of DNA encoding co-stimulatory molecules enhances the efficacy of immune response to foreign antigen
    NHMRC Project Grant
    Open grant
  • 2004 - 2006
    Development of a vaccine for human metapneumovirus-associated respiratory disease in children
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2005
    NHMRC_Equipment Grant _HLTH_CICR_Med SCD
    NHMRC Equipment Grant
    Open grant
  • 2004 - 2005
    Novel cancer vaccine delivery using recombinant Hepatitus B surface antigen VLP- and DNA vectors
    Queensland Cancer Fund
    Open grant
  • 2003 - 2004
    Novel polytope VLP vaccines for respiratory syncytial virus (RSV) infection in children
    Royal Children's Hospital Foundation
    Open grant
  • 2002
    Development of a HBV-specific carrier matrix to induce an immune response against quasispecies-like infectious agents
    NHMRC Project Grant
    Open grant
  • 2001 - 2003
    A Vaccine to Break Tolerance to Cervical Carcunoma Oncoprotein
    NHMRC Project Grant
    Open grant
  • 2000 - 2002
    A polyepitope HPV 16 E7 DNA vaccine restricted through multiple class 1 haplotypes protects against E7-expressing tumour
    NHMRC Project Grant
    Open grant
  • 1999
    A 'polyepitope' DNA vaccine encoding CTL epitopes of HPV16 E7 restricted by multiple MHC class 1 haplotypes, protects against endogenous E7-expressing epithelial tumour: a cervical cancer DNA vaccine
    Cancer Bequest Fund
    Open grant
  • 1999 - 2000
    A recombinant Kunjin virus replicon vaccine will protect against the growth of a tumour expressing a tumour specific antigen
    Queensland Cancer Fund
    Open grant
  • 1999 - 2001
    Immunological Consequences of Epithelial Expression of a Viral Oncoprotein Associated with Cervical Carcinoma
    NHMRC Project Grant
    Open grant
  • 1998 - 1999
    The Body's Responses to Antigens in Skin in Adult Life
    Royal Children's Hospital Foundation
    Open grant
  • 1998 - 1999
    A novel recombinant Hepatitis D virus-like particle vaccine elicits human MHC calss 1 restricted CTL responses, which protect against establishment and growth of tumours expressing the E7 oncoprotein
    Queensland Cancer Fund
    Open grant
  • 1997
    Immunological consequences of neo-antigen presentation at the periphery
    UQ External Support Enabling Grant
    Open grant
  • 1997
    Neo-antigen presentation at the periphery
    Royal Children's Hospital Foundation
    Open grant
  • 1996 - 1998
    Human papillomavirus (HPV) 16 E7 and squamous cell cancer: CTL and tumour protection elicited by oral recombinant Salmonella vaccines containing human CTL epitopes
    Queensland Cancer Fund
    Open grant
  • 1996 - 1997
    Immunity to peripheral 'non-self' antigen in mice transgenic for HPV transforming protein
    Queensland Cancer Fund
    Open grant
  • 1996
    Immunological consequences of neo-antigen presentation at the periphery
    NHMRC Project Grant
    Open grant
  • 1996 - 1999
    Viral research
    Sir Albert Sakzewski Virus Research Centre
    Open grant
  • 1996 - 1997
    Human papillomavirus (HPV) 16 E7 and squamous cell cancer: CTL and tumour protection elicited by oral recombinant Salmonella vaccines containing human CTL epitopes
    Queensland Cancer Fund
    Open grant
  • 1996
    Immunological consequences of neo-antigen presentation at the periphery
    NHMRC Project Grant
    Open grant
  • 1995 - 1998
    The immunobiology of HPV-associated cancers
    United States National Institutes of Health
    Open grant
  • 1995 - 1996
    Immunity to peripheral 'non-self' antigen in mice transgenic for HPV transforming protein
    Queensland Cancer Fund
    Open grant

Availability

Emeritus Professor Robert Tindle is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

Contact Emeritus Professor Robert Tindle directly for media enquiries about:

  • Human papillomavirus
  • Human respiratory viruses
  • Immune system and disease
  • Immunisation
  • Immunology
  • Papillomavirus
  • Respiratory viruses
  • T-cells
  • Vaccines
  • Viral immunology
  • Virology
  • Viruses

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