
Overview
Background
Nick Shaw was appointed to the School as Professor in January 2004 and undertook the role of Head of School of Pharmacy at UQ from 1st July 2004 until 31st December 2014. Nick is a pharmacist, graduating PhD from the University of Manchester in 1985 and was a member of the academic staff of the University of Nottingham from 1985-2003. He was appointed a Fellow of the Royal Society of Chemistry in 1994 and a Fellow of the Royal Pharmaceutical Society in 2010. He previously founded and chaired the Council of Pharmacy Schools (Australia and New Zealand); he is the chair of the APC Accreditation Committee and was the chair of the Australian Pharmacy Liaison Forum in 2011. He has taught across a range of subjects to the second and third years of the BPharm (Hons) course at UQ. Nick has supervised and co-supervised over 45 PhD and research Masters students.
In 2013 Nick was awarded the Pharmaceutical Society of Australia’s Bowl of Hygeia for services to the profession.
Availability
- Professor Nick Shaw is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, The University of Manchester
- Doctor of Philosophy, The University of Manchester
- Fellow, Royal Pharmaceutical Society of Great Britain, Royal Pharmaceutical Society of Great Britain
- Fellow, Royal Society of Chemistry, Royal Society of Chemistry
Research interests
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Application of a range of analytical methodologies to solve clinical and health-related problems
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Metabolite profiling methodology applied to nutrient profiles of tropical and other plants and secondary metabolite identification and quantitation from bacteria
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Drug metabolism, biopharmaceutics, drug delivery and pharmacokinetic studies
Works
Search Professor Nick Shaw’s works on UQ eSpace
1993
Journal Article
Bovine pulmonary, hepatic and renal tissues: models for the study of mammalian C-S lyase enzymes
Buckberry, L.D., Blagbrough, I.S., Bycroft, B.W. and Shaw, P.N. (1993). Bovine pulmonary, hepatic and renal tissues: models for the study of mammalian C-S lyase enzymes. Alternatives to Laboratory Animals, 21 (3), 360-370.
1993
Journal Article
An improved extraction method for the HPLC determination of morphine and its metabolites in plasma
Pawula, Maria, Barrett, David A. and Shaw, P. Nicholas (1993). An improved extraction method for the HPLC determination of morphine and its metabolites in plasma. Journal of Pharmaceutical and Biomedical Analysis, 11 (4-5), 401-406. doi: 10.1016/0731-7085(93)80036-Z
1993
Journal Article
The development of a high performance liquid chromatographic assay method to determine pyruvate generated during the C-S lysis of cysteine conjugated xenobiotics
Buckberry, Lorraine D., Gallagher, S. Dawn and Shaw, P. Nicholas (1993). The development of a high performance liquid chromatographic assay method to determine pyruvate generated during the C-S lysis of cysteine conjugated xenobiotics. Journal of Liquid Chromatography, 16 (14), 3073-3081. doi: 10.1080/10826079308019633
1992
Journal Article
Kynurenine aminotransferase/human hepatic C-S lyase: Preliminary structure-activity relationship studies
Blagbrough, Ian S., Buckberry, Lorraine D., Bycroft, Barrie W. and Shaw, P. Nicholas (1992). Kynurenine aminotransferase/human hepatic C-S lyase: Preliminary structure-activity relationship studies. Bioorganic and Medicinal Chemistry Letters, 2 (10), 1219-1224. doi: 10.1016/S0960-894X(00)80217-6
1992
Journal Article
Human hepatic C-S lyase: Transamination reactions and significant differences between kynurenine aminotransferase and kynureninase
Buckberry, Lorraine D., Bycroft, Barrie W., Shaw, P. Nicholas and Blagbrough, Ian S. (1992). Human hepatic C-S lyase: Transamination reactions and significant differences between kynurenine aminotransferase and kynureninase. Bioorganic and Medicinal Chemistry Letters, 2 (10), 1225-1230. doi: 10.1016/S0960-894X(00)80218-8
1992
Journal Article
The effect of temperature and pH on the deacetylation of diamorphine in aqueous solution and in human plasma
Barrett, D.A., Dyssegaard, A.L.P. and Shaw, P.N. (1992). The effect of temperature and pH on the deacetylation of diamorphine in aqueous solution and in human plasma. Journal of Pharmacy and Pharmacology, 44 (7), 606-608. doi: 10.1111/j.2042-7158.1992.tb05474.x
1992
Journal Article
High-performance liquid chromatographic determination of naproxen, ibuprofen and diclofenac in plasma and synovial fluid in man
Blagbrough, Ian S., Daykin, Mavis M., Doherty, Michael, Pattrick, Martin and Shaw, P. Nicholas (1992). High-performance liquid chromatographic determination of naproxen, ibuprofen and diclofenac in plasma and synovial fluid in man. Journal of Chromatography. Biomedical Applications, 578 (2), 251-257. doi: 10.1016/0378-4347(92)80423-N
1992
Journal Article
Kynurenine aminotransferase activity in human liver: identity with human hepatic C-S lyase activity and a physiological role for this enzyme
Buckberry, Lorraine D., Blagbrough, Ian S., Bycroft, Barrie W. and Shaw, P. Nicholas (1992). Kynurenine aminotransferase activity in human liver: identity with human hepatic C-S lyase activity and a physiological role for this enzyme. Toxicology Letters, 60 (3), 241-246. doi: 10.1016/0378-4274(92)90281-N
1992
Journal Article
The pharmacokinetics of trilostane and ketotrilostane in an interconverting system in the rat
McGee, J. Paul and Shaw, P. Nicholas (1992). The pharmacokinetics of trilostane and ketotrilostane in an interconverting system in the rat. Pharmaceutical Research, 9 (4), 464-468. doi: 10.1023/A:1015828027060
1991
Journal Article
Diamorphine infusion in the preterm neonate
Elias-Jones, A.C., Barrett, D.A., Rutter, N., Shaw, P.N. and Davis, S.S. (1991). Diamorphine infusion in the preterm neonate. Archives of Disease in Childhood, 66 (10), 1155-1157.
1991
Journal Article
Morphine kinetics after diamorphine infusion in premature neonates
Barrett, D.A., Elias-Jones, A.C., Rutter, N., Shaw, P.N. and Davis, S.S. (1991). Morphine kinetics after diamorphine infusion in premature neonates. British Journal of Clinical Pharmacology, 32 (1), 31-37. doi: 10.1111/j.1365-2125.1991.tb05609.x
1991
Journal Article
High-performance liquid chromatographic analysis of trilostane and ketotrilostane in rat plasma
McGee, J.P., Palin, K.J., Shaw, P.N. and Potter, C. (1991). High-performance liquid chromatographic analysis of trilostane and ketotrilostane in rat plasma. Journal of Chromatography. Biomedical Applications, 567 (1), 282-287. doi: 10.1016/0378-4347(91)80333-8
1991
Journal Article
Determination of morphine and 6-acetylmorphine in plasma by high-perfromance liquid chromatography with fluorescence detection
Barrett, D.A., Shaw, P.N. and Davis, S.S. (1991). Determination of morphine and 6-acetylmorphine in plasma by high-perfromance liquid chromatography with fluorescence detection. Journal of Chromatography. Biomedical Applications, 566 (1), 135-145. doi: 10.1016/0378-4347(91)80118-V
1990
Journal Article
Human renal C-S lyases: two cytosolic isoenzymes
Buckberry, Lorraine D., Blagbrough, Ian S., Bycroft, Barrie W. and Shaw, P. Nicholas (1990). Human renal C-S lyases: two cytosolic isoenzymes. Toxicology Letters, 53 (1-2), 253-255. doi: 10.1016/0378-4274(90)90141-8
1990
Journal Article
Human renal C-S lyase: structure-activity relationships of cytosolic and mitochondrial enzymes
Blagbrough, Ian S., Buckberry, Lorraine D., Bycroft, Barrie W. and Shaw, P.Nicholas (1990). Human renal C-S lyase: structure-activity relationships of cytosolic and mitochondrial enzymes. Toxicology Letters, 53 (1-2), 257-259. doi: 10.1016/0378-4274(90)90142-9
1990
Journal Article
THE SYNTHESIS AND ENZYMATIC DEGRADATION OF DEXTRANMETHOTREXATE CONJUGATES
Dellow, Jan L., Blagbrough, Ian S., Davies, Martyn C. and Shaw, P. Nicholas (1990). THE SYNTHESIS AND ENZYMATIC DEGRADATION OF DEXTRANMETHOTREXATE CONJUGATES. Journal of Pharmacy and Pharmacology, 42 (1 S), 41P-41P. doi: 10.1111/j.2042-7158.1990.tb14414.x
1990
Journal Article
HUMAN HEPATIC C‐S LYASE: CO‐PURIFICATION WITH KYNURENINE AMINO TRANSFERASE
Buckberry, Lorraine D., Blagbrough, Ian S., Bycroft, Barrie W. and Shaw, P. Nicholas (1990). HUMAN HEPATIC C‐S LYASE: CO‐PURIFICATION WITH KYNURENINE AMINO TRANSFERASE. Journal of Pharmacy and Pharmacology, 42 (1 S), 30P-30P. doi: 10.1111/j.2042-7158.1990.tb14403.x
1990
Journal Article
PHARMACOKINETICS OF ISOTRETINOIN IN THE ANAESTHETIZED RAT FOLLOWING INTRAVENOUS ADMINISTRATION OF AN EMULSION
Nankervis, R., Cheema, M. S., Davis, S. S., Day, N. H. and Shaw, P. N. (1990). PHARMACOKINETICS OF ISOTRETINOIN IN THE ANAESTHETIZED RAT FOLLOWING INTRAVENOUS ADMINISTRATION OF AN EMULSION. Journal of Pharmacy and Pharmacology, 42 (1 S), 35P-35P. doi: 10.1111/j.2042-7158.1990.tb14408.x
1990
Journal Article
ANALYSIS AND PHYSICOCHEMICAL ASPECTS OF BIOCOMPATIBLE POLYMER CONJUGATES
Dellow, Jan L., Blagbrough, Ian S., Davies, Martyn C. and Shaw, P. Nicholas (1990). ANALYSIS AND PHYSICOCHEMICAL ASPECTS OF BIOCOMPATIBLE POLYMER CONJUGATES. Journal of Pharmacy and Pharmacology, 42 (1 S), 113P-113P. doi: 10.1111/j.2042-7158.1990.tb14486.x
1989
Conference Publication
Synovial fluid and plasma levels of extended release ibuprofen in osteo- and rheumatoid arthritis
Blagbrough, I. S., Daykin, M. M., Doherty, M., Pattrick, M. and Shaw, P. N. (1989). Synovial fluid and plasma levels of extended release ibuprofen in osteo- and rheumatoid arthritis. Unknown, Unknown, Unknown.
Funding
Supervision
Availability
- Professor Nick Shaw is:
- Available for supervision
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Available projects
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The Identification and Quantitation of Opioid Peptides using LC/MS/MS and their Role in Inflammatory Disease
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Bioanalysis, Bioavailability and Disposition of Phytochemicals from Tropical Fruits
Supervision history
Current supervision
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Doctor Philosophy
Enhancing professional identity formation of pharmacy students for effective collaborative interprofessional practice: an international design-based research study
Associate Advisor
Other advisors: Professor Ian Coombes, Associate Professor Christy Noble
-
Doctor Philosophy
Bioactive breastmilk pasteurised by nanosecond pulsed electric field
Associate Advisor
Other advisors: Dr Negareh Ghasemi, Professor Nidhi Bansal
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Doctor Philosophy
Exploring the Multifaceted Value of Milk and Milk Products: Beyond Nutrients to Innate Immunity
Associate Advisor
Other advisors: Professor Mark Turner, Professor Nidhi Bansal
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Doctor Philosophy
Developing functional powders from camel milk
Associate Advisor
Other advisors: Dr Alberto Baldelli, Professor Nidhi Bansal
Completed supervision
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2022
Doctor Philosophy
Assessment of some clinically important elements in infants and young children from Australia and Bangladesh
Principal Advisor
Other advisors: Dr Karen Whitfield
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2021
Doctor Philosophy
Metabolite and lipid profiling of plasma and urine in an obese population using an untargeted approach: Biomarker discovery in obesity
Principal Advisor
Other advisors: Associate Professor Marie-Odile Parat
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2020
Doctor Philosophy
The Application of Population Modelling to Improve the Estimation of Screening Limits in Racehorses
Principal Advisor
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2018
Doctor Philosophy
Development of an assay for vitamin D in biological samples
Principal Advisor
Other advisors: Dr Amitha Hewavitharana, Dr Karen Whitfield
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2018
Doctor Philosophy
Evaluation of Pittosporum angustifolium Lodd. leaf extracts for their biological activities and chemical profiles
Principal Advisor
Other advisors: Associate Professor Marie-Odile Parat
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2014
Doctor Philosophy
Polymeric matrix devices for controlled delivery of agents to prevent bacterial and viral infections
Principal Advisor
Other advisors: Professor Mark Turner
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2022
Doctor Philosophy
Alternative pasteurisation of donor human milk
Associate Advisor
Other advisors: Professor Nidhi Bansal
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2021
Doctor Philosophy
Physico-chemical, Biological and Nutritional Properties of Australian Camel Milk and Its Powder
Associate Advisor
Other advisors: Professor Nidhi Bansal
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2019
Doctor Philosophy
Novel extraction and evaluation of papaya leaf for chemotherapeutic molecules
Associate Advisor
Other advisors: Associate Professor Marie-Odile Parat, Dr James Robert Falconer
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2018
Doctor Philosophy
'Prescriptions for Success': a mixed methods exploration of engagement, learning and academic performance among successful CALD (culturally and linguistically diverse) and non-CALD pharmacy students at a research-intensive Australian university
Associate Advisor
Other advisors: Dr Caroline Steel, Dr Catherine Manathunga
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2018
Doctor Philosophy
MORPHINE AND CANCER METASTASIS
Associate Advisor
Other advisors: Professor Peter Cabot, Professor David Sturgess, Associate Professor Marie-Odile Parat
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2017
Doctor Philosophy
Essential Trace Element Analysis of Human Breast Milk
Associate Advisor
Other advisors: Dr Amitha Hewavitharana, Dr Karen Whitfield
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2017
Doctor Philosophy
Development of polyphenols with improved drug-likeness as prospective disease-modifying drugs for Alzheimer's disease
Associate Advisor
Other advisors: Dr Ben Ross
-
2017
Doctor Philosophy
Ligand- and structure-based discovery of small molecules that modulate the kynurenine pathway for the treatment of Alzheimer's disease
Associate Advisor
Other advisors: Dr Ben Ross
-
2017
Doctor Philosophy
The immunomodulation of dynorphin 1-17 and its biotransformation fragments on inflammatory signalling pathways
Associate Advisor
Other advisors: Professor Peter Cabot, Associate Professor Paul Gray
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2017
Doctor Philosophy
Investigation of Selective Anti-Proliferative and Immunomodulatory Properties of Carica Papaya
Associate Advisor
Other advisors: Professor Peter Cabot, Dr Amitha Hewavitharana
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2016
Doctor Philosophy
Development of an assay for total vitamin D content in milk and application to study the effect of pasteurisation in breastmilk
Associate Advisor
Other advisors: Dr Karen Whitfield, Dr Amitha Hewavitharana
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2016
Doctor Philosophy
Investigation of bioactive compounds with anti-cancer potential in Carica papaya leaves
Associate Advisor
Other advisors: Associate Professor Marie-Odile Parat, Dr Amitha Hewavitharana
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2016
Doctor Philosophy
Novel cholinesterase inhibitors for Alzheimer's disease
Associate Advisor
Other advisors: Dr Ben Ross
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2015
Doctor Philosophy
Beta-Endorphin Biotransformation and Modulation of Inflammatory Signals
Associate Advisor
Other advisors: Professor Peter Cabot, Dr Amitha Hewavitharana
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2014
Doctor Philosophy
Study of the chemical diversity of the actinobacteria genus Salinispora, isolated from Great Barrier Reef Sponges
Associate Advisor
Other advisors: Emeritus Professor John Fuerst, Dr Amitha Hewavitharana
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2014
Doctor Philosophy
Becoming Pharmacists: How the pharmacy curriculum influences professional identity formation
Associate Advisor
Other advisors: Professor Lisa Nissen, Professor Ian Coombes
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2014
Doctor Philosophy
Biochemistry of Salivary Nucleotide Metabolites and their Role in the Innate Immunity of Neonates
Associate Advisor
-
2013
Doctor Philosophy
Developmental cycle and the regulation of natural products in the antibiotic-producing actinobacterium Salinispora from marine sponges
Associate Advisor
Other advisors: Emeritus Professor John Fuerst, Dr Amitha Hewavitharana
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2013
Doctor Philosophy
The Development of Cyclodextrin-Poly(acrylic acid) Conjugates for Sustained Drug Delivery
Associate Advisor
Other advisors: Dr Ben Ross
-
2013
Doctor Philosophy
Use of high throughput techniques in the assessment of the bioactivity of mango extracts
Associate Advisor
Other advisors: Professor Gregory Monteith, Dr Ralf Dietzgen, Professor Mike Gidley
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2013
Doctor Philosophy
A study of the activity and efficacy of beta endorphin fragments in inflamed tissue
Associate Advisor
Other advisors: Dr Amitha Hewavitharana, Professor Peter Cabot
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2012
Doctor Philosophy
Genetic and chemical diversity of the actinobacterial genus Salinispora isolated from Great Barrier Reef sponges.
Associate Advisor
Other advisors: Emeritus Professor John Fuerst, Dr Amitha Hewavitharana
-
2012
Doctor Philosophy
Effect of glycosaminoglycan mimetics and polyphenols on the aggregation and neurotoxicity of Alzheimer's beta-amyloid peptide (1-40)
Associate Advisor
Other advisors: Dr Ben Ross
-
2010
Doctor Philosophy
Characterisation of biological activities of mango fruit components using cell-based assays
Associate Advisor
Other advisors: Professor Gregory Monteith, Dr Ralf Dietzgen, Professor Mike Gidley
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2010
Doctor Philosophy
The peripheral mechanisms of analgesia and the involvement of adhesion molecules - Development of a novel targeted drug delivery system to sites of inflammation and application to peripheral analgesia
Associate Advisor
Other advisors: Dr Amitha Hewavitharana, Professor Peter Cabot
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2008
Doctor Philosophy
Investigation into Immuno-Stimulating COMplexes and Saponin Quil A.
Associate Advisor
-
2008
Master Philosophy
Microencapsulated immunostimulating complexes (ISCOMs) as a basis for single-shot vaccines
Associate Advisor
Other advisors: Dr Harendra Parekh
Media
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