
Overview
Background
Dr Liu is a research fellow with more than 15 years of experience in the field of pharmacometrics. She specialises in population pharmacokinetic modelling and provides popPK analysis and dosing simulation support for various projects in Centre of Research Excellence RESPOND
Availability
- Dr Xin Liu is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, National University of Singapore
Works
Search Professor Xin Liu’s works on UQ eSpace
2010
Conference Publication
Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients
Roberts, D. M., Roberts, M. S., Liu, X., Roberts, J. A., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ESICM 2010: 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October, 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-1999-x
2010
Conference Publication
Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients
Roberts, D., Roberts, M., Liu, X., Roberts, J., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ANZSN 2010: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2010.01377_1.x
2010
Journal Article
Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model
Zou, Yu-Hong, Liu, Xin, Khlentzos, Alexander M., Asadian, Peyman, Li, Peng, Thorling, Camilla A., Robertson, Thomas A., Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2010). Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model. Drug Metabolism and Pharmacokinetics, 25 (5), 442-449. doi: 10.2133/dmpk.DMPK-10-RG-031
2009
Journal Article
Influence of perfusate composition on drug disposition in the in-situ perfused rat lung
Liu, X., Wang, J. Y., Khlentzos, A. M., Fontaine, F., Nikolovski, J., Goh, L.- A. and Roberts, M. S. (2009). Influence of perfusate composition on drug disposition in the in-situ perfused rat lung. International Journal of Pharmaceutics, 382 (1-2), 192-197. doi: 10.1016/j.ijpharm.2009.08.028
2009
Book Chapter
Optimizing drug dosing in the ICU
Kruger, P., Liu, X. and Roberts, M. S. (2009). Optimizing drug dosing in the ICU. Optimizing Drug Dosing in the ICU. (pp. 859-869) edited by Vincent, JL. Berlin, Germany: Springer. doi: 10.1007/978-3-540-92276-6
2008
Journal Article
Comparison of the in vitro and in vivo effects of retinoids either alone or in combination with cisplatin and 5-fluorouracil on tumor development and metastasis of melanoma.
Liu, Xin, Chan, S. Y. and Ho, P. C. (2008). Comparison of the in vitro and in vivo effects of retinoids either alone or in combination with cisplatin and 5-fluorouracil on tumor development and metastasis of melanoma.. Cancer Chemotherapy and Pharmacology, 63 (1), 167-174. doi: 10.1007/s00280-008-0763-1
2008
Journal Article
The prediction of the hepatic clearance of Tanshinone IIA in a rat liver subcellular fractions: accuracy improvement
Li, P., Wang, G-J., Li, J., Liu, X., Khlentzos, A. and Roberts, M. S. (2008). The prediction of the hepatic clearance of Tanshinone IIA in a rat liver subcellular fractions: accuracy improvement. Current Drug Metabolism, 9 (1), 39-45. doi: 10.2174/138920008783331103
2007
Journal Article
In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species
Venkadesh, Pilla Reddy, Goh, Evelyn, Zeng, Peizi, New, Lee Sun, Liu, Xin, Pasha, Mohammed Khalid, Sangthongpitag, Kanda, Yeo, Pauline and Kantharaj, Ethirajulu (2007). In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species. Biological and Pharmaceutical Bulletin, 30 (5), 1021-1024. doi: 10.1248/bpb.30.1021
2007
Journal Article
Development and validation of high-performance liquid chromatography-tandem mass spectrometry assay for 6-(3-benzoyl-ureido)-hexanoic acid hydroxyamide, a novel HDAC inhibitor, in mouse plasma for pharmacokinetic studies
Yeo, Pauline, Xin, Liu, Goh, Evelyn, New, Lee Sun, Zeng, Peizi, Wu, Xiaofeng, Venkatesh, P. and Kantharaj, Ethirajulu (2007). Development and validation of high-performance liquid chromatography-tandem mass spectrometry assay for 6-(3-benzoyl-ureido)-hexanoic acid hydroxyamide, a novel HDAC inhibitor, in mouse plasma for pharmacokinetic studies. Biomedical Chromatography, 21 (2), 184-189. doi: 10.1002/bmc.734
2006
Conference Publication
ADME and PK/PD attributes of SB939, a potent orally active HDAC inhibitor
Sangthongpitag, K., Wang, H., Yeo, P., Liu, X., Goh, E., New, L., Zeng, P., Wu, X., Hu, C. and Ethirajulu, K. (2006). ADME and PK/PD attributes of SB939, a potent orally active HDAC inhibitor. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/S1359-6349(06)70172-0
2005
Journal Article
Characterization of the 13-cis-retinoic acid/cyclodextrin inclusion complexes by phase solubility, photostability, physicochemical and computational analysis
Yap, K. L., Liu, X., Thenmozhiyal, J. C. and Ho, P. C. (2005). Characterization of the 13-cis-retinoic acid/cyclodextrin inclusion complexes by phase solubility, photostability, physicochemical and computational analysis. European Journal of Pharmaceutical Sciences, 25 (1), 49-56. doi: 10.1016/j.ejps.2005.01.021
2004
Journal Article
Biopharmaceutics of beta-cyclodextrin derivative-based formulations of acitretin in Sprague-Dawley rats
Liu, X., Lin, H. S., Chan, S. Y. and Ho, P. C. (2004). Biopharmaceutics of beta-cyclodextrin derivative-based formulations of acitretin in Sprague-Dawley rats. Journal of Pharmaceutical Sciences, 93 (4), 805-815. doi: 10.1002/jps.10578
2003
Journal Article
Inclusion of acitretin into cyclodextrins: Phase solubility, photostability, and physicochemical characterization
Liu, X., Lin, H. S., Thenmozhiyal, J. C., Chan, S. Y. and Ho, P. C. (2003). Inclusion of acitretin into cyclodextrins: Phase solubility, photostability, and physicochemical characterization. Journal of Pharmaceutical Sciences, 92 (12), 2449-2457. doi: 10.1002/jps.10495
Supervision
Availability
- Dr Xin Liu is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles
Associate Advisor
Other advisors: Dr Mark Coulthard, Professor Jeffrey Lipman, Dr Patty Mitre, Professor Jason Roberts
Completed supervision
-
2017
Doctor Philosophy
Real-time optical imaging of the liver: diagnosis and prediction of treatment response
Principal Advisor
Other advisors: Emeritus Professor Michael Roberts
-
2023
Doctor Philosophy
Development of artificial mesenchymal stem cells for hepatocellular carcinoma drug delivery
Associate Advisor
Other advisors: Dr Haolu Wang, Emeritus Professor Michael Roberts
-
2022
Doctor Philosophy
Pharmacotherapy consideration in hospitalized older diabetic and cardiovascular disease patients aged 75 years and above with polypharmacy
Associate Advisor
Other advisors: Dr Xiaowen Liang, Emeritus Professor Michael Roberts
-
2021
Doctor Philosophy
Modeling approaches to predict human skin absorption of drugs and other chemicals
Associate Advisor
Other advisors: Associate Professor Yousuf Mohammed, Emeritus Professor Michael Roberts
-
2019
Doctor Philosophy
Development of optimal experimental conditions for evaluation of topical products
Associate Advisor
Other advisors: Associate Professor Yousuf Mohammed, Emeritus Professor Michael Roberts
-
2016
Doctor Philosophy
Targeted skin delivery of topically applied drugs by optimised formulation design
Associate Advisor
Other advisors: Emeritus Professor Michael Roberts
-
2015
Doctor Philosophy
Biodistribution of newly developed water-dispersible CdTe/CdS quantum dots for in vivo imaging
Associate Advisor
Other advisors: Emeritus Professor Michael Roberts
-
2014
Doctor Philosophy
Pharmacokinetics, Pharmacodynamics and Safety of Marbofloxacin and Trovafloxacin in Sheep
Associate Advisor
Other advisors: Emeritus Professor Michael Roberts
-
2014
Doctor Philosophy
Herbicide nephrotoxicity in rat and human
Associate Advisor
Other advisors: Emeritus Professor Michael Roberts
-
2011
Doctor Philosophy
Drug Disposition in Liver Disease: Liver histopathology and hepatic drug transporter activity as determinants of drug disposition in liver diseases
Associate Advisor
Other advisors: Emeritus Professor Michael Roberts
Media
Enquiries
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