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2025 Journal Article Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO studyAbdul-Aziz, Mohd H., Diehl, Arne, Liu, Xin, Cheng, Vesa, Corley, Amanda, Gilder, Eileen, Levkovich, Bianca, McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Pellegrino, Vincent, Wallis, Steven C., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2025). Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 69 (2) e0143524, 1-15. doi: 10.1128/aac.01435-24 |
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2025 Journal Article Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patientsKumta, Nilesh, Heffernan, Aaron J., Liu, Xin, Parker, Suzanne L., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wai, Wong Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2025). Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients. International Journal of Antimicrobial Agents, 65 (5) 107461, 107461-5. doi: 10.1016/j.ijantimicag.2025.107461 |
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2025 Journal Article A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE)Gurunathan, Usha, Medcalf, Robert L., Chiang, Lily, Liu, Zikou, Liu, Xin, Keragala, Charithani B., Hernandez-Mitre, Maria Patricia, Brady, Paul, Wallis, Steven C., Roberts, Jason A., Mullany, Daniel, Nandurkar, Harshal, Eley, Victoria and Parker, Suzanne L. (2025). A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE). British Journal of Anaesthesia. doi: 10.1016/j.bja.2024.12.004 |
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2025 Journal Article Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysisTognolini, Angela R., Liu, Xin, Pandey, Saurabh, Roberts, Jason A., Wallis, Steven C., Jackson, Dwane and Eley, Victoria A. (2025). Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysis. Anaesthesia, 80 (5), 511-521. doi: 10.1111/anae.16531 |
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2024 Journal Article Population pharmacokinetics and dosing simulations of temocillin in liver-transplanted paediatric patients: a prospective, open-label, non-randomized studyNgougni Pokem, Perrin, Stéphenne, Xavier, Liu, Xin, Parker, Suzanne L., Van der Linden, Dimitri, Godet, Marie-Laura, Wijnant, Gert-Jan, Chatzis, Olga, Houtekie, Laurent, Haenecour, Astrid, Sokal, Etienne, Roberts, Jason A., Elens, Laure and Van Bambeke, Françoise (2024). Population pharmacokinetics and dosing simulations of temocillin in liver-transplanted paediatric patients: a prospective, open-label, non-randomized study. Clinical Microbiology and Infection, 31 (3), 408-416. doi: 10.1016/j.cmi.2024.12.015 |
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2024 Journal Article Continuous infusion of piperacillin/tazobactam optimizes intraoperative antibiotic exposure in patients undergoing elective pelvic exenteration surgeryJackson, Dwane, Ulldemolins, Marta, Liu, Xin, Harris, Craig, Tognolini, Angela, Wallis, Steven C., Sumi, Chandra, Parker, Suzanne L., Eley, Victoria and Roberts, Jason A. (2024). Continuous infusion of piperacillin/tazobactam optimizes intraoperative antibiotic exposure in patients undergoing elective pelvic exenteration surgery. Antimicrobial Agents and Chemotherapy, 68 (12), e0111624. doi: 10.1128/aac.01116-24 |
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2024 Journal Article Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric studyNovy, Emmanuel, Liu, Xin, Hernandez-Mitre, Maria Patricia, Belveyre, Thibaut, Scala-Bertola, Julien, Roberts, Jason A. and Parker, Suzanne L. (2024). Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study. Anaesthesia Critical Care and Pain Medicine, 43 (3) 101376, 1-8. doi: 10.1016/j.accpm.2024.101376 |
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2024 Journal Article Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitisNgougni Pokem, Perrin, Liu, Xin, Parker, Suzanne L., Verroken, Alexia, Collienne, Christine, Finet, Patrice, Wijnant, Gert-Jan, Laterre, Pierre-François, Roberts, Jason A., Van Bambeke, Françoise and Wittebole, Xavier (2024). Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis. Journal of Antimicrobial Chemotherapy, 79 (2), 429-442. doi: 10.1093/jac/dkad398 |
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2022 Journal Article Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactionsZou, Da, Wu, Zeming, Yi, Xin, Hui, Yue, Yang, Guangze, Liu, Yun, Tengjisi,, Wang, Haofei, Brooks, Anastasia, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S., Gao, Huajian and Zhao, Chun-Xia (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences, 120 (1) e2214757120, e2214757120. doi: 10.1073/pnas.2214757120 |
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2022 Journal Article Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testingLiu, Xin, Cheruvu, Hanumanth S., Anissimov, Yuri G., van der Hoek, John, Tsakalozou, Eleftheria, Ni, Zhanglin, Ghosh, Priyanka, Grice, Jeffrey E. and Roberts, Michael S. (2022). Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing. International Journal of Pharmaceutics, 625 122095, 1-16. doi: 10.1016/j.ijpharm.2022.122095 |
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2022 Journal Article Efficacy and safety of immune-modulating therapy for primary sclerosing cholangitis: a systematic review and meta-analysisLiu, Xin, Wang, Haolu, Liu, Xinyao, Bridle, Kim, Crawford, Darrell and Liang, Xiaowen (2022). Efficacy and safety of immune-modulating therapy for primary sclerosing cholangitis: a systematic review and meta-analysis. Pharmacology and Therapeutics, 237 108163, 1-13. doi: 10.1016/j.pharmthera.2022.108163 |
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2022 Journal Article An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutionsCheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E and Roberts, Michael S. (2022). An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions. Data in Brief, 42 108242, 1-9. doi: 10.1016/j.dib.2022.108242 |
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2021 Journal Article Artificial cells for the treatment of liver diseasesZou, Da, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S. and Zhao, Chun-Xia (2021). Artificial cells for the treatment of liver diseases. Acta Biomaterialia, 130, 98-114. doi: 10.1016/j.actbio.2021.06.012 |
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2021 Journal Article Relating transdermal delivery plasma pharmacokinetics with in vitro permeation test (IVPT) findings using diffusion and compartment-in-series modelsLiu, Xin, Anissimov, Yuri G., Grice, Jeffrey E., Cheruvu, Hanumanth Srikanth, Ghosh, Priyanka, Raney, Sam G., Maibach, Howard and Roberts, Michael S. (2021). Relating transdermal delivery plasma pharmacokinetics with in vitro permeation test (IVPT) findings using diffusion and compartment-in-series models. Journal of Controlled Release, 334, 37-51. doi: 10.1016/j.jconrel.2021.04.010 |
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2020 Journal Article Diffusion modelling of percutaneous absorption kinetics. Predicting urinary excretion from in vitro skin permeation tests (IVPT) for an infinite doseLiu, Xin, Yousef, Shereen, Anissimov, Yuri G., van der Hoek, John, Tsakalozou, Eleftheria, Ni, Zhanglin, Grice, Jeffrey E. and Roberts, Michael S. (2020). Diffusion modelling of percutaneous absorption kinetics. Predicting urinary excretion from in vitro skin permeation tests (IVPT) for an infinite dose. European Journal of Pharmaceutics and Biopharmaceutics, 149, 30-44. doi: 10.1016/j.ejpb.2020.01.018 |
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2020 Journal Article Modeling percutaneous absorption for successful drug discovery and developmentCheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E. and Roberts, Michael S. (2020). Modeling percutaneous absorption for successful drug discovery and development. Expert Opinion on Drug Discovery, 15 (10), 1-18. doi: 10.1080/17460441.2020.1781085 |
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2020 Conference Publication Multiphoton and FLIM imaging in quantifying ex vivo and in vivo body organ kinetics of solutesRoberts, Michael S., Barkauskas, Deborah, Wang, Haolu, Liu, Xin, Studier, Hauke, Pastore, Michael, Zhang, Run, Holmes, Amy, Grice, Jeffrey E., Xu, Zhiping, Mohammed, Yousuf S. and Liang, Xiaowen (2020). Multiphoton and FLIM imaging in quantifying ex vivo and in vivo body organ kinetics of solutes. Multiphoton Microscopy in the Biomedical Sciences, San Francisco, CA United States, 2-4 February 2020. Bellingham, WA United States: SPIE. doi: 10.1117/12.2546058 |
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2020 Journal Article Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injuryWang, Haolu, Burke, Leslie J., Patel, Jatin, Tse, Brian W.C., Bridle, Kim R., Cogger, Victoria C., Li, Xinxing, Liu, Xin, Yang, Haotian, Crawford, Darrell H. G., Roberts, Michael S., Gao, Wenchao and Liang, Xiaowen (2020). Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury. Theranostics, 10 (15), 6715-6727. doi: 10.7150/thno.44900 |
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2018 Journal Article Anionic long-circulating quantum dots for long-term intravital vascular imagingWang, Haolu, Yang, Haotian, Xu, Zhi Ping, Liu, Xin, Roberts, Michael S. and Liang, Xiaowen (2018). Anionic long-circulating quantum dots for long-term intravital vascular imaging. Pharmaceutics, 10 (4) 244, 244. doi: 10.3390/pharmaceutics10040244 |
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2018 Journal Article Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocarcinogenesis via modulating TGF-β/tβr and imp7/8Wu, Chao, Kan, Hongwei, Hu, Min, Liu, Xin, Boye, Alex, Jiang, Yufeng, Wu, Jiajun, Wang, Jiyu, Yang, Xiaochuan and Yang, Yan (2018). Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocarcinogenesis via modulating TGF-β/tβr and imp7/8. Experimental and Therapeutic Medicine, 16 (2), 1052-1060. doi: 10.3892/etm.2018.6292 |
