Overview
Background
Michael (Mike) Roberts is a NHMRC Senior Principal Research Fellow and Emeritus Professor of Clinical Pharmacology & Therapeutics and Director of the Therapeutics Research Centre in the Diamantina Institute at The University of Queensland, which is based in the Translational Research Institute adjacent to the Princess Alexandra Hospital in Brisbane, Qld, Australia. He is also Professor of Therapeutics & Pharmaceutical Science at the University of South Australia with laboratories in the Basil Hetzel Institute at The Queen Elizabeth Hospital in Adelaide, South Australia.
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Pharmacy, University of Adelaide
- Masters (Coursework) of Science, University of Sydney
- Doctor of Philosophy, University of Sydney
- Masters (Coursework) of Business Administration, The University of Queensland
- Doctoral Diploma of Science (Advanced), University of Sydney
Works
Search Professor Michael Roberts’s works on UQ eSpace
2024
Journal Article
Multiple topical product dermatitis: paradigms in understanding and future perspectives
Mangion, Sean E., Mikkonen, Antti, Mackenzie, Lorraine, Roberts, Michael S. and Maibach, Howard I. (2024). Multiple topical product dermatitis: paradigms in understanding and future perspectives. JEADV Clinical Practice, 3 (1), 49-64. doi: 10.1002/jvc2.293
2024
Journal Article
Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity
Qiang, Shuping, Mohamed, Fahim, Raubenheimer, Jacques, Buckley, Nicholas A., Roberts, Michael S. and Mackenzie, Lorraine (2024). Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity. Clinical Toxicology, 62 (8), 483-496. doi: 10.1080/15563650.2024.2375584
2023
Journal Article
Dynamic exposure and body burden models for per- and polyfluoroalkyl substances (PFAS) enable management of food safety risks in cattle
Mikkonen, Antti T., Martin, Jennifer, Upton, Richard N., Moenning, Jan-Louis, Numata, Jorge, Taylor, Mark P., Roberts, Michael S. and Mackenzie, Lorraine (2023). Dynamic exposure and body burden models for per- and polyfluoroalkyl substances (PFAS) enable management of food safety risks in cattle. Environment International, 180 108218. doi: 10.1016/j.envint.2023.108218
2023
Journal Article
Human skin drug metabolism: relationships between methyl salicylate metabolism and esterase activities in IVPT skin membranes
Telaprolu, Krishna C., Grice, Jeffrey E., Mohammed, Yousuf H. and Roberts, Michael S. (2023). Human skin drug metabolism: relationships between methyl salicylate metabolism and esterase activities in IVPT skin membranes. Metabolites, 13 (8) 934, 1-12. doi: 10.3390/metabo13080934
2023
Journal Article
Spatio-temporal trends in livestock exposure to per- and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures
Mikkonen, Antti T., Martin, Jennifer, Upton, Richard N., Barker, Andrew O., Brumley, Carolyn M., Taylor, Mark P., Mackenzie, Lorraine and Roberts, Michael S. (2023). Spatio-temporal trends in livestock exposure to per- and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures. Environmental Research, 225 115518, 1-14. doi: 10.1016/j.envres.2023.115518
2023
Journal Article
Seborrheic dermatitis: topical therapeutics and formulation design
Mangion, Sean E., Mackenzie, Lorraine, Roberts, Michael S. and Holmes, Amy M. (2023). Seborrheic dermatitis: topical therapeutics and formulation design. European Journal of Pharmaceutics and Biopharmaceutics, 185, 148-164. doi: 10.1016/j.ejpb.2023.01.023
2023
Journal Article
Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS
Qiang, Shuping, Mohamed, Fahim, Mackenzie, Lorraine and Roberts, Michael S. (2023). Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS. Talanta, 254 124115, 1-12. doi: 10.1016/j.talanta.2022.124115
2023
Journal Article
A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. Maximum flux and solute diffusion through stratum corneum lipids
Zhang, Qian, Alinaghi, Azadeh, Williams, Desmond B. and Roberts, Michael S. (2023). A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. Maximum flux and solute diffusion through stratum corneum lipids. International Journal of Pharmaceutics, 631 122522, 1-11. doi: 10.1016/j.ijpharm.2022.122522
2023
Journal Article
Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning
Alinaghi, Azadeh, Zhang, Qian, Williams, Desmond B., Mackenzie, Lorraine and Roberts, Michael S. (2023). Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning. International Journal of Pharmaceutics, 630 122424, 1-10. doi: 10.1016/j.ijpharm.2022.122424
2023
Journal Article
In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines
Forouz, Farzaneh, Mohammed, Yousuf, Nejad, Hamid S. A. Shobeiri, Roberts, Michael S. and Grice, Jeffrey E. (2023). In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines. EXCLI Journal, 22, 1173-1199. doi: 10.17179/excli2023-6072
2022
Journal Article
Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions
Zou, Da, Wu, Zeming, Yi, Xin, Hui, Yue, Yang, Guangze, Liu, Yun, Tengjisi,, Wang, Haofei, Brooks, Anastasia, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S., Gao, Huajian and Zhao, Chun-Xia (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences, 120 (1) e2214757120, e2214757120. doi: 10.1073/pnas.2214757120
2022
Journal Article
Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing
Liu, Xin, Cheruvu, Hanumanth S., Anissimov, Yuri G., van der Hoek, John, Tsakalozou, Eleftheria, Ni, Zhanglin, Ghosh, Priyanka, Grice, Jeffrey E. and Roberts, Michael S. (2022). Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing. International Journal of Pharmaceutics, 625 122095, 1-16. doi: 10.1016/j.ijpharm.2022.122095
2022
Journal Article
Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model
Arora, Sumit, Clarke, James, Tsakalozou, Eleftheria, Ghosh, Priyanka, Alam, Khondoker, Grice, Jeffery E., Roberts, Michael S., Jamei, Masoud and Polak, Sebastian (2022). Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model. Molecular Pharmaceutics, 19 (9), 3139-3152. doi: 10.1021/acs.molpharmaceut.2c00229
2022
Journal Article
Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum
Amarah, A. A., Hadgraft, J., Roberts, M. S. and Anissimov, Y. G. (2022). Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum. International Journal of Pharmaceutics, 623 121902, 1-10. doi: 10.1016/j.ijpharm.2022.121902
2022
Journal Article
Advances and future perspectives in epithelial drug delivery
Mohammed, Yousuf, Holmes, Amy, Kwok, Philip Chi Lip, Kumeria, Tushar, Namjoshi, Sarika, Imran, Mohammad, Matteucci, Lana, Ali, Masood, Tai, Waiting, Benson, Heather A.E. and Roberts, Michael S. (2022). Advances and future perspectives in epithelial drug delivery. Advanced Drug Delivery Reviews, 186 114293, 1-38. doi: 10.1016/j.addr.2022.114293
2022
Journal Article
An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions
Cheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E and Roberts, Michael S. (2022). An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions. Data in Brief, 42 108242, 1-9. doi: 10.1016/j.dib.2022.108242
2022
Journal Article
Multi-modal imaging to assess the follicular delivery of zinc pyrithione
Mangion, Sean E., Sandiford, Lydia, Mohammed, Yousuf, Roberts, Michael S. and Holmes, Amy M. (2022). Multi-modal imaging to assess the follicular delivery of zinc pyrithione. Pharmaceutics, 14 (5) 1076, 1-14. doi: 10.3390/pharmaceutics14051076
2022
Journal Article
Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients
Al-Qurain, Aymen A., Upton, Richard N., Tadros, Rami, Roberts, Michael S. and Wiese, Michael D. (2022). Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients. European Journal of Drug Metabolism and Pharmacokinetics, 47 (3), 387-402. doi: 10.1007/s13318-022-00756-x
2022
Journal Article
In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics
Rowland, Malcolm, Roberts, Michael S. and Pang, K Sandy (2022). In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics. Drug metabolism and disposition: the biological fate of chemicals, 50 (2), 187-190. doi: 10.1124/dmd.121.000637
2022
Book Chapter
Theranostic nanoparticles for imaging and targeted drug delivery to the liver
Wang, Haolu, Yang, Haotian, Ruan, Qi, Roberts, Michael S. and Liang, Xiaowen (2022). Theranostic nanoparticles for imaging and targeted drug delivery to the liver. Fundamentals of drug delivery. (pp. 311-328) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781119769644.ch12
Funding
Current funding
Past funding
Supervision
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Thermodynamic dependence of Topical Formulations
Associate Advisor
Other advisors: Associate Professor Peter Moyle, Dr Yousuf Mohammed
-
Doctor Philosophy
Injection of Supercritical and Near-Critical Fluids into Supersonic Crossflow
Associate Advisor
Other advisors: Dr Tristan Vanyai, Professor Anand Veeraragavan
Completed supervision
-
2023
Doctor Philosophy
Development of artificial mesenchymal stem cells for hepatocellular carcinoma drug delivery
Principal Advisor
Other advisors: Dr Xin Liu, Dr Haolu Wang
-
2022
Doctor Philosophy
Pharmacotherapy consideration in hospitalized older diabetic and cardiovascular disease patients aged 75 years and above with polypharmacy
Principal Advisor
Other advisors: Dr Xin Liu, Dr Xiaowen Liang
-
2021
Doctor Philosophy
Modeling approaches to predict human skin absorption of drugs and other chemicals
Principal Advisor
Other advisors: Dr Yousuf Mohammed, Dr Xin Liu
-
2019
Doctor Philosophy
Development of optimal experimental conditions for evaluation of topical products
Principal Advisor
Other advisors: Dr Yousuf Mohammed, Dr Xin Liu
-
2017
Doctor Philosophy
Embedding the Clinician-Researcher Pharmacist in Healthcare
Principal Advisor
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Jeffrey Lipman
-
2015
Doctor Philosophy
Biodistribution of newly developed water-dispersible CdTe/CdS quantum dots for in vivo imaging
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Pharmacokinetics, Pharmacodynamics and Safety of Marbofloxacin and Trovafloxacin in Sheep
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Herbicide nephrotoxicity in rat and human
Principal Advisor
Other advisors: Dr Xin Liu
-
2013
Doctor Philosophy
Statin Therapy in Patients with Sepsis: From Retrospective Analysis to RCT
Principal Advisor
-
2011
Doctor Philosophy
Drug Disposition in Liver Disease: Liver histopathology and hepatic drug transporter activity as determinants of drug disposition in liver diseases
Principal Advisor
Other advisors: Dr Xin Liu
-
2010
Doctor Philosophy
The effect of resuscitation fluids on beta lactam antibiotic pharamacokinetics in interstitial tissue in acute thermal injury
Principal Advisor
Other advisors: Professor Bala Venkatesh
-
-
2006
Master Philosophy
IONTOPHORESIS OF THE NAIL
Principal Advisor
-
2006
Doctor Philosophy
AXOPLASMIC TRANSPORT AND TRANSEPIDERMAL IONTOPHORESIS: FACTORS IN NEUROGENIC PAIN MANAGEMENT
Principal Advisor
-
2005
Master Philosophy
PERCUTANEOUS PENETRATION OF PARABENS THROUGH HUMAN EPDIERMAL MEMBRANE
Principal Advisor
-
2005
Doctor Philosophy
DISPOSITION PHARMACOKINETICS AND EFFECTS OF SOLUTES AND DRUGS IN PERFUSED ORGAN SYSTEMS
Principal Advisor
-
2004
Doctor Philosophy
MEDICATION CARE: DATABASES, DRUG USE AND OUTCOMES
Principal Advisor
-
2004
Doctor Philosophy
PHARMACOEPIDEMIOLOGY OF MEDICATION USE BY THE COMMUNITY-BASED ELDERLY
Principal Advisor
-
2003
Doctor Philosophy
A COMPARISON OF THE APPROPRIATENESS OF PSYCHOTROPIC DRUG AND POLYPHARMACY USE IN MENTAL HEALTH, IN INSTITUTIONALISED PATIENTS AND IN THE COMMUNITY
Principal Advisor
-
2003
Doctor Philosophy
QUALITY OF MEDICATION CARE IN LONG TERM CARE FACILITIES: ASSESSMENT OF PROCESS, NEEDS AND TYPE OF INTERVENTION
Principal Advisor
-
2002
Doctor Philosophy
THE STUDIES OF ALCOHOLIC LIVER DISEASE (ALD): PATHOGENESIS, PHARMACOKINETICS AND THERAPEUTIC APPROACHES
Principal Advisor
-
2002
Doctor Philosophy
IDENTIFICATION AND PURIFICATION OF THE JOINT SURFACTANT PROTEINS
Principal Advisor
-
2002
Doctor Philosophy
THE EFFECT OF CHEMICAL STRUCTURE ON THE ABSORPTION OF SUNSCREENS THROUGH THE SKIN
Principal Advisor
-
2023
Doctor Philosophy
Human mesenchymal stem cell-derived liver-on-a-chip for the study of cell migration
Associate Advisor
Other advisors: Dr Kim Bridle, Dr Xiaowen Liang, Dr Haolu Wang
-
2022
Doctor Philosophy
The Characterisation of Tumour Self-Seeded Cells in Liver Cancer
Associate Advisor
Other advisors: Dr Haolu Wang, Dr Xiaowen Liang
-
2020
Doctor Philosophy
Enhanced topical drug delivery for treatment of human melanoma
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard, Dr Yousuf Mohammed, Associate Professor Helmut Schaider
-
2019
Doctor Philosophy
Evaluation of a Ketogenic Formulation for Treating Patients with Acute Brain Injury
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2017
Doctor Philosophy
Real-time optical imaging of the liver: diagnosis and prediction of treatment response
Associate Advisor
Other advisors: Professor Darrell Crawford, Dr Xin Liu
-
2016
Doctor Philosophy
EFFECT OF TOPICAL MAGNESIUM APPLICATION ON EPIDERMAL INTEGRITY AND BARRIER FUNCTION
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard
-
2016
Doctor Philosophy
Targeted skin delivery of topically applied drugs by optimised formulation design
Associate Advisor
Other advisors: Dr Xin Liu
-
2014
Master Philosophy
Development of a soluble macrolide formulation and identification of potential benefits in chronic rhinosinusitis.
Associate Advisor
-
2013
Doctor Philosophy
Particulate Penetration and Metabolic Effects in Human Skin
Associate Advisor
-
2009
Doctor Philosophy
Beta-lactam antibiotic dosing in critical care units: Bolus vs continuous dosing
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2008
Doctor Philosophy
Depression in Parkinson's disease: assessment methods and risk factors
Associate Advisor
Other advisors: Associate Professor John O'Sullivan
-
2005
Doctor Philosophy
SURFACTANT PROTEINS IN EXTRA PULMONARY SITES
Associate Advisor
Media
Enquiries
Contact Emeritus Professor Michael Roberts directly for media enquiries about:
- Clinical pharmacology
- Drug analysis
- Drug delivery - pharmacology
- Drug structure-disposition relationships
- Health care delivery
- Hepatic metabolism
- Medication care
- Pharmacokinetics
- Pharmacology
- Topical (skin) products
- Toxicology - drugs
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