
Overview
Background
Michael (Mike) Roberts is a NHMRC Senior Principal Research Fellow and Emeritus Professor of Clinical Pharmacology & Therapeutics and Director of the Therapeutics Research Centre in the Diamantina Institute at The University of Queensland, which is based in the Translational Research Institute adjacent to the Princess Alexandra Hospital in Brisbane, Qld, Australia. He is also Professor of Therapeutics & Pharmaceutical Science at the University of South Australia with laboratories in the Basil Hetzel Institute at The Queen Elizabeth Hospital in Adelaide, South Australia.
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Pharmacy, University of Adelaide
- Masters (Coursework) of Science, University of Sydney
- Doctor of Philosophy, University of Sydney
- Masters (Coursework) of Business Administration, The University of Queensland
- Doctoral Diploma of Science (Advanced), University of Sydney
Works
Search Professor Michael Roberts’s works on UQ eSpace
2022
Journal Article
An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions
Cheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E and Roberts, Michael S. (2022). An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions. Data in Brief, 42 108242, 1-9. doi: 10.1016/j.dib.2022.108242
2022
Journal Article
Multi-modal imaging to assess the follicular delivery of zinc pyrithione
Mangion, Sean E., Sandiford, Lydia, Mohammed, Yousuf, Roberts, Michael S. and Holmes, Amy M. (2022). Multi-modal imaging to assess the follicular delivery of zinc pyrithione. Pharmaceutics, 14 (5) 1076, 1-14. doi: 10.3390/pharmaceutics14051076
2022
Journal Article
Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients
Al-Qurain, Aymen A., Upton, Richard N., Tadros, Rami, Roberts, Michael S. and Wiese, Michael D. (2022). Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients. European Journal of Drug Metabolism and Pharmacokinetics, 47 (3), 387-402. doi: 10.1007/s13318-022-00756-x
2022
Journal Article
In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics
Rowland, Malcolm, Roberts, Michael S. and Pang, K Sandy (2022). In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics. Drug metabolism and disposition: the biological fate of chemicals, 50 (2), 187-190. doi: 10.1124/dmd.121.000637
2022
Book Chapter
Theranostic nanoparticles for imaging and targeted drug delivery to the liver
Wang, Haolu, Yang, Haotian, Ruan, Qi, Roberts, Michael S. and Liang, Xiaowen (2022). Theranostic nanoparticles for imaging and targeted drug delivery to the liver. Fundamentals of drug delivery. (pp. 311-328) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781119769644.ch12
2022
Journal Article
Application of confocal raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo
Jung, Nathalie, Namjoshi, Sarika, Mohammed, Yousuf, Grice, Jeffrey E., Benson, Heather A. E., Raney, Sam G., Roberts, Michael S. and Windbergs, Maike (2022). Application of confocal raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo. Pharmaceutical Research, 39 (5), 935-948. doi: 10.1007/s11095-022-03245-7
2022
Book
Oral drug delivery for modified release formulations
Edmund S. Kostewicz, Maria Vertzoni, Heather A. E. Benson and Michael S. Roberts eds. (2022). Oral drug delivery for modified release formulations. Hoboken, NJ, United States: John Wiley and Sons Inc.. doi: 10.1002/9781119772729
2022
Journal Article
Predicting viable skin concentration: modelling the subpapillary plexus
Calcutt, Joshua J., Roberts, Michael S. and Anissimov, Yuri G. (2022). Predicting viable skin concentration: modelling the subpapillary plexus. Pharmaceutical Research, 39 (4), 783-793. doi: 10.1007/s11095-022-03215-z
2022
Book Chapter
Challenges and innovations of controlled drug delivery
Benson, Heather A.E. and Roberts, Michael S. (2022). Challenges and innovations of controlled drug delivery. Fundamentals of Drug Delivery. (pp. 3-14) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: Wiley. doi: 10.1002/9781119769644.ch1
2021
Journal Article
Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens
Khabir, Zahra, Holmes, Amy M., Lai, Yi-Jen, Liang, Liuen, Deva, Anand, Polikarpov, Michael A., Roberts, Michael S. and Zvyagin, Andrei V. (2021). Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens. International Journal of Molecular Sciences, 22 (22) 12372, 12372. doi: 10.3390/ijms222212372
2021
Journal Article
Topical drug delivery: history, percutaneous absorption, and product development
Roberts, Michael S., Cheruvu, Hanumanth S., Mangion, Sean E., Alinaghi, Azadeh, Benson, Heather A.E., Mohammed, Yousuf, Holmes, Amy, van der Hoek, John, Pastore, Michael and Grice, Jeffrey E. (2021). Topical drug delivery: history, percutaneous absorption, and product development. Advanced Drug Delivery Reviews, 177 113929, 113929. doi: 10.1016/j.addr.2021.113929
2021
Journal Article
Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetric absorptive micro sampling
Al-Qurain, Aymen A., Williams, Desmond B., Mackenzie, Lorraine, Roberts, Michael S. and Wiese, Michael D. (2021). Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetric absorptive micro sampling. Journal of Pharmaceutical and Biomedical Analysis, 203 114171, 1-8. doi: 10.1016/j.jpba.2021.114171
2021
Journal Article
Targeted delivery of zinc pyrithione to skin epithelia
Mangion, Sean E., Holmes, Amy M. and Roberts, Michael S. (2021). Targeted delivery of zinc pyrithione to skin epithelia. International Journal of Molecular Sciences, 22 (18) 9730, 9730. doi: 10.3390/ijms22189730
2021
Journal Article
Viscoelastic and deformation characteristics of structurally different commercial topical systems
Dabbaghi, Maryam, Namjoshi, Sarika, Panchal, Bhavesh, Grice, Jeffrey E., Prakash, Sangeeta, Roberts, Michael Stephen and Mohammed, Yousuf (2021). Viscoelastic and deformation characteristics of structurally different commercial topical systems. Pharmaceutics, 13 (9) 1351, 1351. doi: 10.3390/pharmaceutics13091351
2021
Journal Article
Liver organoid as a 3D in vitro model for drug validation and toxicity assessment
Brooks, Anastasia, Liang, Xiaowen, Zhang, Yonglong, Zhao, Chun-Xia, Roberts, Michael S., Wang, Haolu, Zhang, Lei and Crawford, Darrell H.G. (2021). Liver organoid as a 3D in vitro model for drug validation and toxicity assessment. Pharmacological Research, 169 105608, 105608. doi: 10.1016/j.phrs.2021.105608
2021
Journal Article
Artificial cells for the treatment of liver diseases
Zou, Da, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S. and Zhao, Chun-Xia (2021). Artificial cells for the treatment of liver diseases. Acta Biomaterialia, 130, 98-114. doi: 10.1016/j.actbio.2021.06.012
2021
Journal Article
Relating transdermal delivery plasma pharmacokinetics with in vitro permeation test (IVPT) findings using diffusion and compartment-in-series models
Liu, Xin, Anissimov, Yuri G., Grice, Jeffrey E., Cheruvu, Hanumanth Srikanth, Ghosh, Priyanka, Raney, Sam G., Maibach, Howard and Roberts, Michael S. (2021). Relating transdermal delivery plasma pharmacokinetics with in vitro permeation test (IVPT) findings using diffusion and compartment-in-series models. Journal of Controlled Release, 334, 37-51. doi: 10.1016/j.jconrel.2021.04.010
2021
Journal Article
Efficacy and safety of statins in ethnic differences: A lesson for application in Indigenous Australian patient care
Gebremichael, Lemlem G., Suppiah, Vijayaprakash, Wiese, Michael D., Mackenzie, Lorraine, Phillips, Craig, Williams, Desmond B. and Roberts, Michael S. (2021). Efficacy and safety of statins in ethnic differences: A lesson for application in Indigenous Australian patient care. Pharmacogenomics, 22 (9), 553-571. doi: 10.2217/pgs-2020-0152
2021
Journal Article
Case fatality of agricultural pesticides after self-poisoning in Sri Lanka: a prospective cohort study
Buckley, Nicholas A., Fahim, Mohamed, Raubenheimer, Jacques, Gawarammana, Indika B., Eddleston, Michael, Roberts, Michael S. and Dawson, Andrew H. (2021). Case fatality of agricultural pesticides after self-poisoning in Sri Lanka: a prospective cohort study. The Lancet Global Health, 9 (6), e854-e862. doi: 10.1016/S2214-109X(21)00086-3
2021
Journal Article
Acute phenthoate self-poisoning: a prospective case series
Rambabu, Lekaashree, Mohamed, Fahim, Dhanarisi, Jeevan, Gawarammana, Indika, Raubenheimer, Jacques, Mackenzie, Lorraine, Roberts, Michael S., Buckley, Nicholas and Eddleston, Michael (2021). Acute phenthoate self-poisoning: a prospective case series. Clinical Toxicology, 60 (2), 1-7. doi: 10.1080/15563650.2021.1917596
Funding
Current funding
Past funding
Supervision
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Injection of Supercritical and Near-Critical Fluids into Supersonic Crossflow
Associate Advisor
Other advisors: Dr Tristan Vanyai, Professor Anand Veeraragavan
Completed supervision
-
2023
Doctor Philosophy
Development of artificial mesenchymal stem cells for hepatocellular carcinoma drug delivery
Principal Advisor
Other advisors: Dr Xin Liu, Dr Haolu Wang
-
2022
Doctor Philosophy
Pharmacotherapy consideration in hospitalized older diabetic and cardiovascular disease patients aged 75 years and above with polypharmacy
Principal Advisor
Other advisors: Dr Xin Liu, Dr Xiaowen Liang
-
2021
Doctor Philosophy
Modeling approaches to predict human skin absorption of drugs and other chemicals
Principal Advisor
Other advisors: Associate Professor Yousuf Mohammed, Dr Xin Liu
-
2019
Doctor Philosophy
Development of optimal experimental conditions for evaluation of topical products
Principal Advisor
Other advisors: Associate Professor Yousuf Mohammed, Dr Xin Liu
-
2017
Doctor Philosophy
Embedding the Clinician-Researcher Pharmacist in Healthcare
Principal Advisor
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Jeffrey Lipman
-
2015
Doctor Philosophy
Biodistribution of newly developed water-dispersible CdTe/CdS quantum dots for in vivo imaging
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Pharmacokinetics, Pharmacodynamics and Safety of Marbofloxacin and Trovafloxacin in Sheep
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Herbicide nephrotoxicity in rat and human
Principal Advisor
Other advisors: Dr Xin Liu
-
2013
Doctor Philosophy
Statin Therapy in Patients with Sepsis: From Retrospective Analysis to RCT
Principal Advisor
-
2011
Doctor Philosophy
Drug Disposition in Liver Disease: Liver histopathology and hepatic drug transporter activity as determinants of drug disposition in liver diseases
Principal Advisor
Other advisors: Dr Xin Liu
-
2010
Doctor Philosophy
The effect of resuscitation fluids on beta lactam antibiotic pharamacokinetics in interstitial tissue in acute thermal injury
Principal Advisor
Other advisors: Professor Bala Venkatesh
-
-
2006
Doctor Philosophy
AXOPLASMIC TRANSPORT AND TRANSEPIDERMAL IONTOPHORESIS: FACTORS IN NEUROGENIC PAIN MANAGEMENT
Principal Advisor
-
2006
Master Philosophy
IONTOPHORESIS OF THE NAIL
Principal Advisor
-
2005
Master Philosophy
PERCUTANEOUS PENETRATION OF PARABENS THROUGH HUMAN EPDIERMAL MEMBRANE
Principal Advisor
-
2005
Doctor Philosophy
DISPOSITION PHARMACOKINETICS AND EFFECTS OF SOLUTES AND DRUGS IN PERFUSED ORGAN SYSTEMS
Principal Advisor
-
2004
Doctor Philosophy
MEDICATION CARE: DATABASES, DRUG USE AND OUTCOMES
Principal Advisor
-
2004
Doctor Philosophy
PHARMACOEPIDEMIOLOGY OF MEDICATION USE BY THE COMMUNITY-BASED ELDERLY
Principal Advisor
-
2003
Doctor Philosophy
QUALITY OF MEDICATION CARE IN LONG TERM CARE FACILITIES: ASSESSMENT OF PROCESS, NEEDS AND TYPE OF INTERVENTION
Principal Advisor
-
2003
Doctor Philosophy
A COMPARISON OF THE APPROPRIATENESS OF PSYCHOTROPIC DRUG AND POLYPHARMACY USE IN MENTAL HEALTH, IN INSTITUTIONALISED PATIENTS AND IN THE COMMUNITY
Principal Advisor
-
2002
Doctor Philosophy
THE STUDIES OF ALCOHOLIC LIVER DISEASE (ALD): PATHOGENESIS, PHARMACOKINETICS AND THERAPEUTIC APPROACHES
Principal Advisor
-
2002
Doctor Philosophy
IDENTIFICATION AND PURIFICATION OF THE JOINT SURFACTANT PROTEINS
Principal Advisor
-
2002
Doctor Philosophy
THE EFFECT OF CHEMICAL STRUCTURE ON THE ABSORPTION OF SUNSCREENS THROUGH THE SKIN
Principal Advisor
-
2023
Doctor Philosophy
Human mesenchymal stem cell-derived liver-on-a-chip for the study of cell migration
Associate Advisor
Other advisors: Dr Kim Bridle, Dr Xiaowen Liang, Dr Haolu Wang
-
2022
Doctor Philosophy
The Characterisation of Tumour Self-Seeded Cells in Liver Cancer
Associate Advisor
Other advisors: Dr Haolu Wang, Dr Xiaowen Liang
-
2020
Doctor Philosophy
Enhanced topical drug delivery for treatment of human melanoma
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard, Associate Professor Yousuf Mohammed, Associate Professor Helmut Schaider
-
2019
Doctor Philosophy
Evaluation of a Ketogenic Formulation for Treating Patients with Acute Brain Injury
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2017
Doctor Philosophy
Real-time optical imaging of the liver: diagnosis and prediction of treatment response
Associate Advisor
Other advisors: Dr Xin Liu
-
2016
Doctor Philosophy
EFFECT OF TOPICAL MAGNESIUM APPLICATION ON EPIDERMAL INTEGRITY AND BARRIER FUNCTION
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard
-
2016
Doctor Philosophy
Targeted skin delivery of topically applied drugs by optimised formulation design
Associate Advisor
Other advisors: Dr Xin Liu
-
2014
Master Philosophy
Development of a soluble macrolide formulation and identification of potential benefits in chronic rhinosinusitis.
Associate Advisor
-
2013
Doctor Philosophy
Particulate Penetration and Metabolic Effects in Human Skin
Associate Advisor
-
2009
Doctor Philosophy
Beta-lactam antibiotic dosing in critical care units: Bolus vs continuous dosing
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2008
Doctor Philosophy
Depression in Parkinson's disease: assessment methods and risk factors
Associate Advisor
Other advisors: Associate Professor John O'Sullivan
-
2005
Doctor Philosophy
SURFACTANT PROTEINS IN EXTRA PULMONARY SITES
Associate Advisor
Media
Enquiries
Contact Emeritus Professor Michael Roberts directly for media enquiries about:
- Clinical pharmacology
- Drug analysis
- Drug delivery - pharmacology
- Drug structure-disposition relationships
- Health care delivery
- Hepatic metabolism
- Medication care
- Pharmacokinetics
- Pharmacology
- Topical (skin) products
- Toxicology - drugs
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