Relationship between melanosome distribution and skin colour (2007-2010)
Abstract
This project aims to characterize the number, size, melanin content, number and distribution of melanosomes in relation to colour of skin for various races. This will be achieved by a combination of UV microscopy, electron microscopy and confocal microscopy. The proposed outcome is to be able predict the colour of skin by changing one of the parameters of the melanosome in the different layers of the epidermis. The significance of this project is in defining an alternative pharmacological target for modifying the colour of skin that may lead to innovative therapies which maybe better than current approaches such as the use of harsh bleaches, depigmenting agents and damaging UV light. '',
