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Assessing gene function in the developing vertebrate brain using zebrafish as a model system (2003-2005)

Abstract

Although the vertebrate brain is the most complicated biological tissue it arises from a very simple sheet of cells during embryogenesis. Groups of nerve cells begin to communicate with each other through long interconnecting processes called axons. This project seeks to understand the role of specific genes in this process. This is the first time that the mechanisms controlling the growth of the earliest axons in the vertebrate brain will be examined in a living brain. Our analysis is expected to discover genes that are targets for manipulation of axon growth.

Experts

Professor Brian Key

Affiliate of Centre for Innovation in Pain and Health Research (CIPHeR)
Centre for Innovation in Pain and Health Research
Faculty of Health, Medicine and Behavioural Sciences
Professor
School of Biomedical Sciences
Faculty of Health, Medicine and Behavioural Sciences
Brian Key
Brian Key