Chemical and Biochemical Characterisation of Novel Iron Chelators with Therapeutic Potential (2004-2006)
Abstract
Iron is essential for life but iron-overload is a potentially fatal condition. There is no natural mechanism to excrete iron in humans so patients suffering from iron-overload disorders are treated with the chelator Desferal to enable iron excretion typically from an early age. Desferal is orally ineffective and must be given by subcutaneous infusion