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Molecular and cellular mechanisms of axon guidance in the vertebrate nervous system (2007-2009)

Abstract

There are, at least, two major obstacles that have to be overcome in the design of therapies to assist the repair of injured brain tissue. First, the nerve cells that are damaged have to be encouraged to regrow - typically this regrowth is inhibited in the brain; and second, this regrowth has to be directed so that the correct connections are re-established. This project will begin to unravel some of the mechanisms that nerve cells use to wire up together during development. This information can be used to assist in trying to modulate and facilitate directed regrowth following injury.

Experts

Professor Brian Key

Affiliate of Centre for Innovation in Pain and Health Research (CIPHeR)
Centre for Innovation in Pain and Health Research
Faculty of Health, Medicine and Behavioural Sciences
Professor
School of Biomedical Sciences
Faculty of Health, Medicine and Behavioural Sciences
Brian Key
Brian Key