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How does timing affect mammalian brain development and evolution? (2020-2023)

Abstract

This project aims to generate fundamental knowledge on the origin of diversity in mammalian brain circuits by studying development of marsupials and rodents. The expected outcome is to elucidate how differences in the timing, rate and sequence of development of gene expression, cell differentiation and circuit formation can relate to the origin of key evolutionary innovations in the mammalian brain. The significance of understanding the dynamics of developmental systems that shape complex brain traits includes establishing new developmental paradigms in evolutionary theory, generating new tools to investigate and manipulate brain gene expression in vivo, and the potential discovery of the causes of neurodevelopmental dysfunction.

Experts

Associate Professor Rodrigo Suarez

Associate Professor
School of Biomedical Sciences
Faculty of Health, Medicine and Behavioural Sciences
Rodrigo Suarez
Rodrigo Suarez

Dr Laura Fenlon

Senior Lecturer - Biomedical Sciences
School of Biomedical Sciences
Faculty of Health, Medicine and Behavioural Sciences
Laura Fenlon
Laura Fenlon