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Cell fluid interaction: inside and outside cells (2023-2026)

Abstract

The project aims to measure mechanics at the cellular level using a combination of optical tweezers for measurement of nano-scale environment around/inside cells and light-sheet microscopy for imaging. The project expects to generate new knowledge about movement of cells through their environment, relating to collective behaviour which is of importance in understanding infections and formation of biofilms. Expected outcomes include deepened understanding of an enigmatic process conserved from amoebae to humans, by which cells `drink and eat by `gulping fluid and supplement their nutrient intake by degrading proteins and cell debris. It will generate new knowledge of these processes to better understand how mechanics affects cellular life.

Experts

Professor Halina Rubinsztein-Dunlop

Affiliate of ARC COE for Engineered
ARC Centre of Excellence for Engineered Quantum Systems
Faculty of Science
Affiliate of ARC COE in Quantum Bio
ARC Centre of Excellence in Quantum Biotechnology
Faculty of Science
Professor
School of Mathematics and Physics
Faculty of Science
Halina Rubinsztein-Dunlop
Halina Rubinsztein-Dunlop

Dr Timo Nieminen

Senior Lecturer
School of Mathematics and Physics
Faculty of Science
Timo Nieminen
Timo Nieminen

Professor Jennifer Stow

Affiliate of The Centre for Cell Bi
Centre for Cell Biology of Chronic Disease
Institute for Molecular Bioscience
Affiliate of ARC COE in Quantum Bio
ARC Centre of Excellence in Quantum Biotechnology
Faculty of Science
NHMRC Leadership Fellow
Institute for Molecular Bioscience
Jennifer Stow
Jennifer Stow

Dr Alexander Stilgoe

Affiliate of ARC COE for Engineered
ARC Centre of Excellence for Engineered Quantum Systems
Faculty of Science
Research Fellow
School of Mathematics and Physics
Faculty of Science
Alexander Stilgoe
Alexander Stilgoe