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Super-resolution platform to accelerate biological and molecular research (2024-2025)

Abstract

This application aims to establish a new molecular analysis platform integrating a microfluid capillary electrophoresis interface directly to a mass spectrometer with advanced data scanning technology. This enables label-free detection, quantitation and characterisation of intact proteins, lipids and metabolites with unprecedented sensitivity, resolution and throughput. It will enhance ARC projects spanning natural product discovery, biotechnology, agriculture, and animal, plant and marine biology, as well as single-cell proteomics, lipidomics and metabolomics. It will ensure Australia remains at the forefront of molecular and biological research and create new training and collaborative opportunities both nationally and internationally.

Experts

Professor David Fairlie

Centre Director of The Centre for Chemistry and Drug Discovery
Centre for Chemistry and Drug Discovery
Institute for Molecular Bioscience
Affiliate of ARC COE for Innovations in Peptide and Protein Science
ARC COE for Innovations in Peptide and Protein Science
Institute for Molecular Bioscience
Centre Director of Institute for Molecular Bioscience
Institute for Molecular Bioscience
NHMRC Leadership Fellow and Group Leader
Institute for Molecular Bioscience
David Fairlie
David Fairlie

Associate Professor Markus Muttenthaler

Affiliate of Centre for Chemistry and Drug Discovery
Centre for Chemistry and Drug Discovery
Institute for Molecular Bioscience
ARC Future Fellow & Group Leader
Institute for Molecular Bioscience
Markus Muttenthaler
Markus Muttenthaler

Professor Robert Parton

Affiliate of The Centre for Cell Biology of Chronic Disease
Centre for Cell Biology of Chronic Disease
Institute for Molecular Bioscience
ARC Laureate Fellow - Group Leader
Institute for Molecular Bioscience
Robert Parton
Robert Parton

Professor Irina Vetter

Affiliate of Centre for Innovation in Pain and Health Research (CIPHeR)
Centre for Innovation in Pain and Health Research
Faculty of Health, Medicine and Behavioural Sciences
Affiliate of The Centre for Chemistry and Drug Discovery
Centre for Chemistry and Drug Discovery
Institute for Molecular Bioscience
Affiliate of Centre for Marine Science
Centre for Marine Science
Faculty of Science
NHMRC Leadership Fellow - Group Leader
School of Pharmacy and Pharmaceutical Sciences
Faculty of Health, Medicine and Behavioural Sciences
NHMRC Leadership Fellow - Group Leader
Institute for Molecular Bioscience
Irina Vetter
Irina Vetter

Emeritus Professor Richard Lewis

Affiliate of Centre for Innovation in Pain and Health Research (CIPHeR)
Centre for Innovation in Pain and Health Research
Faculty of Health and Behavioural Sciences
Affiliate of Centre for Marine Science
Centre for Marine Science
Faculty of Science
Affiliate of Centre for Chemistry and Drug Discovery
Centre for Chemistry and Drug Discovery
Institute for Molecular Bioscience
Affiliate Professor of School of Biomedical Sciences
School of Biomedical Sciences
Faculty of Medicine
Professorial Research Fellow - GL
Institute for Molecular Bioscience
Richard Lewis
Richard Lewis