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2017

Journal Article

Claisen rearrangements of benzyl vinyl ethers: theoretical investigation of mechanism, substituent effects, and regioselectivity

Krenske, Elizabeth H., Burns, Jed M. and McGeary, Ross P. (2017). Claisen rearrangements of benzyl vinyl ethers: theoretical investigation of mechanism, substituent effects, and regioselectivity. Organic and Biomolecular Chemistry, 15 (37), 7887-7893. doi: 10.1039/c7ob01666b

Claisen rearrangements of benzyl vinyl ethers: theoretical investigation of mechanism, substituent effects, and regioselectivity

2017

Journal Article

Multistereocenter-containing cyclopentanoids from Ynamides via oxazolidinone-controlled nazarov cyclization

Manchala, Narasimhulu, Law, Hanson Y. L., Kerr, Daniel J., Volpe, Rohan, Lepage, Romain J., White, Jonathan M., Krenske, Elizabeth H. and Flynn, Bernard L. (2017). Multistereocenter-containing cyclopentanoids from Ynamides via oxazolidinone-controlled nazarov cyclization. Journal of Organic Chemistry, 82 (13), 6511-6527. doi: 10.1021/acs.joc.7b00082

Multistereocenter-containing cyclopentanoids from Ynamides via oxazolidinone-controlled nazarov cyclization

2017

Journal Article

An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone

Fisher, Brendan, Lepage, Romain J., White, Jonathan M., Ye, Young, Krenske, Elizabeth H. and Rizzacasa, Mark A. (2017). An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone. Organic & Biomolecular Chemistry, 15 (26), 5529-5534. doi: 10.1039/c7ob01121k

An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone

2017

Journal Article

Ionic and neutral mechanisms for C-H bond silylation of aromatic heterocycles catalyzed by potassium tert-butoxide

Banerjee, Shibdas, Yang, Yun-Fang, Jenkins, Ian D., Liang, Yong, Toutov, Anton A., Liu, Wen-Bo, Schuman, David P., Grubbs, Robert H., Stoltz, Brian M., Krenske, Elizabeth H., Houk, Kendall N. and Zare, Richard N. (2017). Ionic and neutral mechanisms for C-H bond silylation of aromatic heterocycles catalyzed by potassium tert-butoxide. Journal of the American Chemical Society, 139 (20), 6880-6887. doi: 10.1021/jacs.6b13032

Ionic and neutral mechanisms for C-H bond silylation of aromatic heterocycles catalyzed by potassium tert-butoxide

2017

Journal Article

Mechanisms of carbonyl activation by BINOL N-triflylphosphoramides: enantioselective nazarov cyclizations

Lovie-Toon, Joseph P., Tram, Camilla Mia, Flynn, Bernard L. and Krenske, Elizabeth H. (2017). Mechanisms of carbonyl activation by BINOL N-triflylphosphoramides: enantioselective nazarov cyclizations. Acs Catalysis, 7 (5), 3466-3476. doi: 10.1021/acscatal.7b00292

Mechanisms of carbonyl activation by BINOL N-triflylphosphoramides: enantioselective nazarov cyclizations

2017

Journal Article

Aromatic claisen rearrangements of benzyl ketene acetals: conversion of benzylic alcohols to (ortho-tolyl)acetates

Burns, Jed M., Krenske, Elizabeth H. and McGeary, Ross P. (2017). Aromatic claisen rearrangements of benzyl ketene acetals: conversion of benzylic alcohols to (ortho-tolyl)acetates. European Journal of Organic Chemistry, 2017 (2), 252-256. doi: 10.1002/ejoc.201601354

Aromatic claisen rearrangements of benzyl ketene acetals: conversion of benzylic alcohols to (ortho-tolyl)acetates

2017

Journal Article

Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols

Moore, Peter W., Hooker, Jordan P., Zavra, Athanasios, Khairallah, George N., Krenske, Elizabeth H., Bernhardt, Paul V., Quach, Gina, Moore, Evan G., O’Hair, Richard A. J. and William, Craig M. (2017). Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols. Australian Journal of Chemistry, 70 (4), 397-406. doi: 10.1071/CH16602

Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols

2016

Journal Article

Kinetics and thermodynamics of reversible thiol additions to mono- and diactivated Michael acceptors: implications for the design of drugs that bind covalently to cysteines

Krenske, Elizabeth H., Petter, Russell C. and Houk, K. N. (2016). Kinetics and thermodynamics of reversible thiol additions to mono- and diactivated Michael acceptors: implications for the design of drugs that bind covalently to cysteines. Journal of Organic Chemistry, 81 (23), 11726-11733. doi: 10.1021/acs.joc.6b02188

Kinetics and thermodynamics of reversible thiol additions to mono- and diactivated Michael acceptors: implications for the design of drugs that bind covalently to cysteines

2016

Journal Article

The stereoselectivities of tributyltin hydride-mediated reductions of 5-bromo-D-glucuronides to L-iduronides are dependent on the anomeric substituent: syntheses and DFT calculations

Mohamed, Shifaza, Krenske, Elizabeth H. and Ferro, Vito (2016). The stereoselectivities of tributyltin hydride-mediated reductions of 5-bromo-D-glucuronides to L-iduronides are dependent on the anomeric substituent: syntheses and DFT calculations. Organic and Biomolecular Chemistry, 14 (10), 2950-2960. doi: 10.1039/C6OB00283H

The stereoselectivities of tributyltin hydride-mediated reductions of 5-bromo-D-glucuronides to L-iduronides are dependent on the anomeric substituent: syntheses and DFT calculations

2016

Journal Article

Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation

Stok, Jeanette E., Chow, Sharon, Krenske, Elizabeth H., Farfan Soto, Clementina, Matyas, Csongor, Poirier, Raymond A., Williams, Craig M. and De Voss, James J. (2016). Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation. Chemistry: A European Journal, 22 (13), 4408-4412. doi: 10.1002/chem.201600246

Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation

2016

Journal Article

Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases

Brown, Joshua J., Gahan, Lawrence R., Schöffler, Anne, Krenske, Elizabeth H. and Schenk, Gerhard (2016). Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases. Journal of Inorganic Biochemistry, 162, 356-365. doi: 10.1016/j.jinorgbio.2016.02.008

Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases

2015

Journal Article

Towards the synthesis of dihydrooxepino[4,3-b]pyrrole-containing natural products via cope rearrangement of vinyl pyrrole epoxides

Cameron, Alex, Fisher, Brendan, Fisk, Nicholas, Hummel, Jessica, White, Jonathan M., Krenske, Elizabeth H. and Rizzacasa, Mark A. (2015). Towards the synthesis of dihydrooxepino[4,3-b]pyrrole-containing natural products via cope rearrangement of vinyl pyrrole epoxides. Organic Letters, 17 (24), 5998-6001. doi: 10.1021/acs.orglett.5b02965

Towards the synthesis of dihydrooxepino[4,3-b]pyrrole-containing natural products via cope rearrangement of vinyl pyrrole epoxides

2015

Journal Article

Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability

Krenske, Elizabeth H. and Williams, Craig M. (2015). Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability. Angewandte Chemie International Edition, 54 (36), 10608-10612. doi: 10.1002/anie.201503822

Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability

2015

Journal Article

Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa

Challinor, Victoria L., Johnston, Ryne C., Bernhardt, Paul V., Lehmann, Reginald P., Krenske, Elizabeth H. and De Voss, James J. (2015). Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa. Chemical Science, 6 (10), 5740-5745. doi: 10.1039/c5sc02056e

Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa

2015

Journal Article

Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata

White, Andrew M., Pierens, Gregory K., Skinner-Adams, Tina, Andrews, Katherine T., Bernhardt, Paul V., Krenske, Elizabeth H., Mollo, Ernesto and Garson, Mary J. (2015). Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata. Journal of Natural Products, 78 (6), 1422-1427. doi: 10.1021/acs.jnatprod.5b00354

Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata

2015

Journal Article

Concerted ring opening and cycloaddition of chiral epoxy enolsilanes with dienes

Krenske, Elizabeth H., Lam, Sarah, Ng, Jerome P. L., Lo, Brian, Lam, Sze Kui, Chiu, Pauline and Houk, Kendall N. (2015). Concerted ring opening and cycloaddition of chiral epoxy enolsilanes with dienes. Angewandte Chemie (International Edition), 54 (25), 7422-7425. doi: 10.1002/anie.201503003

Concerted ring opening and cycloaddition of chiral epoxy enolsilanes with dienes

2015

Journal Article

Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations

Volpe, Rohan, Aurelio, Luigi, Gillin, Murray G., Krenske, Elizabeth H. and Flynn, Bernard L. (2015). Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations. Chemistry - A European Journal, 21 (28), 10191-10199. doi: 10.1002/chem.201500384

Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations

2015

Journal Article

AlCl3-catalyzed ring expansion cascades of bicyclic cyclobutenamides involving highly strained cis,trans-cycloheptadienone intermediates

Wang, Xiao-Na, Krenske, Elizabeth H., Johnston, Ryne C., Houk, K. N. and Hsung, Richard P. (2015). AlCl3-catalyzed ring expansion cascades of bicyclic cyclobutenamides involving highly strained cis,trans-cycloheptadienone intermediates. Journal of the American Chemical Society, 137 (16), 5596-5601. doi: 10.1021/jacs.5b02561

AlCl3-catalyzed ring expansion cascades of bicyclic cyclobutenamides involving highly strained cis,trans-cycloheptadienone intermediates

2014

Journal Article

Computational Analysis of the Stereochemical Outcome in the Imidazolidinone-Catalyzed Enantioselective (4 + 3)-Cycloaddition Reaction.

Krenske, Elizabeth H., Houk, K. N. and Harmata, Michael (2014). Computational Analysis of the Stereochemical Outcome in the Imidazolidinone-Catalyzed Enantioselective (4 + 3)-Cycloaddition Reaction.. Journal of Organic Chemistry, 80 (2), 744-750. doi: 10.1021/jo501906m

Computational Analysis of the Stereochemical Outcome in the Imidazolidinone-Catalyzed Enantioselective (4 + 3)-Cycloaddition Reaction.

2014

Journal Article

Catalytic wittig reactions of semi- and nonstabilized ylides enabled by ylide tuning

Coyle, Emma E., Doonan, Bryan J., Holohan, Andrew J., Walsh, Killian A., Lavigne, Florie, Krenske, Elizabeth H. and O'Brien, Christopher J. (2014). Catalytic wittig reactions of semi- and nonstabilized ylides enabled by ylide tuning. Angewandte Chemie International Edition, 53 (47), 12907-12911. doi: 10.1002/anie.201406103

Catalytic wittig reactions of semi- and nonstabilized ylides enabled by ylide tuning