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2021

Journal Article

Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy

Ioannides, Zara A., Csurhes, Peter A., Douglas, Nanette L., Mackenroth, Gem, Swayne, Andrew, Thompson, Kate M., Hopkins, Tracey J., Green, Kerryn A., Blum, Stefan, Hooper, Kaye D., Wyssusek, Kerstin H., Coulthard, Alan and Pender, Michael P. (2021). Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy. Frontiers in Neurology, 12 652811, 652811. doi: 10.3389/fneur.2021.652811

Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy

2021

Journal Article

Correlations between macrophage/microglial activation marker sTREM-2 and measures of T-cell activation, neuroaxonal damage and disease severity in multiple sclerosis

Ioannides, Zara A., Csurhes, Peter A., Swayne, Andrew, Foubert, Philippe, Aftab, Blake T. and Pender, Michael P. (2021). Correlations between macrophage/microglial activation marker sTREM-2 and measures of T-cell activation, neuroaxonal damage and disease severity in multiple sclerosis. Multiple Sclerosis Journal Experimental, Translational and Clinical, 7 (2), 1-12. doi: 10.1177/20552173211019772

Correlations between macrophage/microglial activation marker sTREM-2 and measures of T-cell activation, neuroaxonal damage and disease severity in multiple sclerosis

2020

Journal Article

Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis

Pender, Michael P., Csurhes, Peter A., Smith, Corey, Douglas, Nanette L., Neller, Michelle A., Matthews, Katherine K., Beagley, Leone, Rehan, Sweera, Crooks, Pauline, Hopkins, Tracey J., Blum, Stefan, Green, Kerryn A., Ioannides, Zara A., Swayne, Andrew, Aftab, Blake T., Hooper, Kaye D., Burrows, Scott R., Thompson, Kate M., Coulthard, Alan and Khanna, Rajiv (2020). Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis. JCI insight, 5 (20) e144624. doi: 10.1172/jci.insight.144624

Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis

2018

Journal Article

Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis

Pender, Michael P., Csurhes, Peter A., Smith, Corey, Douglas, Nanette L., Neller, Michelle A., Matthews, Katherine K., Beagley, Leone, Rehan, Sweera, Crooks, Pauline, Hopkins, Tracey J., Blum, Stefan, Green, Kerryn A., Ioannides, Zara A., Swayne, Andrew, Aftab, Blake T., Hooper, Kaye D., Burrows, Scott R., Thompson, Kate M., Coulthard, Alan and Khanna, Rajiv (2018). Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis. JCI Insight, 3 (22) e124714. doi: 10.1172/jci.insight.124714

Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis

2017

Journal Article

Defective T-cell control of Epstein-Barr virus infection in multiple sclerosis

Pender, Michael P., Csurhes, Peter A., Burrows, Jacqueline M. and Burrows, Scott R. (2017). Defective T-cell control of Epstein-Barr virus infection in multiple sclerosis. Clinical and Translational Immunology, 6 (1) e126, 1-17. doi: 10.1038/cti.2016.87

Defective T-cell control of Epstein-Barr virus infection in multiple sclerosis

2015

Journal Article

Circulating brain derived neurotrophic factor (BDNF) and frequency of BDNF positive T cells in peripheral blood in human ischemic stroke: effect on outcome

Chan, Adeline, Yan, Jun, Csurhes, Peter, Greer, Judith and McCombe, Pamela (2015). Circulating brain derived neurotrophic factor (BDNF) and frequency of BDNF positive T cells in peripheral blood in human ischemic stroke: effect on outcome. Journal of Neuroimmunology, 286, 42-47. doi: 10.1016/j.jneuroim.2015.06.013

Circulating brain derived neurotrophic factor (BDNF) and frequency of BDNF positive T cells in peripheral blood in human ischemic stroke: effect on outcome

2015

Journal Article

The frequencies of Killer immunoglobulin-like receptors and their HLA ligands in chronic inflammatory demyelinating polyradiculoneuropathy are similar to those in Guillian Barre syndrome but differ from those of controls, suggesting a role for NK cells in

Blum, Stefan, Csurhes, Peter and McCombe, Pamela (2015). The frequencies of Killer immunoglobulin-like receptors and their HLA ligands in chronic inflammatory demyelinating polyradiculoneuropathy are similar to those in Guillian Barre syndrome but differ from those of controls, suggesting a role for NK cells in. Journal of Neuroimmunology, 285, 53-56. doi: 10.1016/j.jneuroim.2015.05.017

The frequencies of Killer immunoglobulin-like receptors and their HLA ligands in chronic inflammatory demyelinating polyradiculoneuropathy are similar to those in Guillian Barre syndrome but differ from those of controls, suggesting a role for NK cells in

2014

Journal Article

Epstein-Barr virus-specific adoptive immunotherapy for progressive multiple sclerosis

Pender, Michael P., Csurhes, Peter A., Smith, Corey, Beagley, Leone, Hooper, Kaye D., Raj, Meenakshi, Coulthard, Alan, Burrows, Scott R. and Khanna, Rajiv (2014). Epstein-Barr virus-specific adoptive immunotherapy for progressive multiple sclerosis. Multiple Sclerosis Journal, 20 (11), 1541-1544. doi: 10.1177/1352458514521888

Epstein-Barr virus-specific adoptive immunotherapy for progressive multiple sclerosis

2014

Journal Article

Killer immunoglobulin-like receptor and their HLA ligands in Guillain-Barré Syndrome

Blum, Stefan, Csurhes, Peter, Reddel, Stephen, Spies, Judy and McCombe, Pamela (2014). Killer immunoglobulin-like receptor and their HLA ligands in Guillain-Barré Syndrome. Journal of Neuroimmunology, 267 (1-2), 92-96. doi: 10.1016/j.jneuroim.2013.12.007

Killer immunoglobulin-like receptor and their HLA ligands in Guillain-Barré Syndrome

2014

Journal Article

Deficiency of CD8+ effector memory T cells is an early and persistent feature of multiple sclerosis

Pender, Michael P., Csurhes, Peter A., Pfluger, Casey M. M. and Burrows, Scott R. (2014). Deficiency of CD8+ effector memory T cells is an early and persistent feature of multiple sclerosis. Multiple Sclerosis Journal, 20 (14), 1825-1832. doi: 10.1177/1352458514536252

Deficiency of CD8+ effector memory T cells is an early and persistent feature of multiple sclerosis

2012

Journal Article

CD8(+) T cells far predominate over CD4(+) T cells in healthy immune response to Epstein-Barr virus infected lymphoblastoid cell lines

Pender, Michael P., Csurhes, Peter A., Pfluger, Casey M. M. and Burrows, Scott R. (2012). CD8(+) T cells far predominate over CD4(+) T cells in healthy immune response to Epstein-Barr virus infected lymphoblastoid cell lines. Blood, 120 (25), 5085-5087. doi: 10.1182/blood-2012-06-437285

CD8(+) T cells far predominate over CD4(+) T cells in healthy immune response to Epstein-Barr virus infected lymphoblastoid cell lines

2012

Journal Article

CD8 T cell deficiency impairs control of Epstein–Barr virus and worsens with age in multiple sclerosis

Pender, Michael P., Csurhes, Peter A., Pfluger, Casey M.M. and Burrows, Scott R. (2012). CD8 T cell deficiency impairs control of Epstein–Barr virus and worsens with age in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 83 (3), 353-354. doi: 10.1136/jnnp-2011-300213

CD8 T cell deficiency impairs control of Epstein–Barr virus and worsens with age in multiple sclerosis

2012

Journal Article

Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis

Yan, Jun, Liu, Jia, Lin, Clement Yihao, Australia and New Zealand Multiple Sclerorsis Genetics Consortium, Csurhes, Peter A., Pender, Michael P., McCombe, Pamela A. and Greer, Judith M. (2012). Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis. International Journal of Molecular Sciences, 13 (10), 13667-13679. doi: 10.3390/ijms131013667

Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis

2011

Journal Article

Decreased CD8(+) T cell response to Epstein-Barr virus infected B cells in multiple sclerosis is not due to decreased HLA class I expression on B cells or monocytes

Pender, Michael P., Csurhes, Peter A ., Pfluger, Casey M. M. and Burrows, Scott R. (2011). Decreased CD8(+) T cell response to Epstein-Barr virus infected B cells in multiple sclerosis is not due to decreased HLA class I expression on B cells or monocytes. BMC Neurology, 11 (1) 95, 95-1-95-6. doi: 10.1186/1471-2377-11-95

Decreased CD8(+) T cell response to Epstein-Barr virus infected B cells in multiple sclerosis is not due to decreased HLA class I expression on B cells or monocytes

2011

Journal Article

Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips

Ritchie, Matthew E., Liu, Ruijie, Carvalho, Benilton S., The Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Irizarry, Rafael A., Brown, Matthew A., Csurhes, Peter A., Danoy, Patrick, Greer, Judith M., Hadler, Johanna, Pryce, Karena and Pender, Michael P. (2011). Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips. BMC Bioinformatics, 12 (4) 68, 68.1-68.12. doi: 10.1186/1471-2105-12-68

Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips

2010

Journal Article

Strains of Epstein-Barr virus infecting multiple sclerosis patients

Brennan, R. M., Burrows, J. M., Bell, M. J., Bromham, L., Csurhes, P. A., Lenarczyk, A., Sverndal, J., Klintenstedt, J., Pender, M. P. and Burrows, S. R. (2010). Strains of Epstein-Barr virus infecting multiple sclerosis patients. Multiple Sclerosis, 16 (6), 643-651. doi: 10.1177/1352458510364537

Strains of Epstein-Barr virus infecting multiple sclerosis patients

2010

Journal Article

Investigation of the [-/A](8) and C1236T genetic variations within the human toll-like receptor 3 gene for association with multiple sclerosis

Szvetko, Attila, Jones, Ashleigh, Mackenzie, Jason, Tajouri, Lotti, Csurhes, Peter, Greer, Judith, Pender, Michael and Griffiths, Lyn (2010). Investigation of the [-/A](8) and C1236T genetic variations within the human toll-like receptor 3 gene for association with multiple sclerosis. Neurological Research [electronic resource], 32 (4), 438-441. doi: 10.1179/174313209X405155

Investigation of the [-/A](8) and C1236T genetic variations within the human toll-like receptor 3 gene for association with multiple sclerosis

2010

Journal Article

T cells from patients with Guillain-Barre syndrome produce interferon-gamma in response to stimulation with the ganglioside GM1

McCombe, P. A. and Csurhes, P. A. (2010). T cells from patients with Guillain-Barre syndrome produce interferon-gamma in response to stimulation with the ganglioside GM1. Journal of Clinical Neuroscience, 17 (4), 537-538. doi: 10.1016/j.jocn.2009.07.096

T cells from patients with Guillain-Barre syndrome produce interferon-gamma in response to stimulation with the ganglioside GM1

2010

Journal Article

Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies

Bahlo, Melanie, Stankovich, Jim, Danoy, Patrick, Hickey, Peter F., Taylor, Bruce V., Browning, Sharon R., The Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Brown, Matthew A., Rubio, Justin P., Csurhes, Peter A., Greer, Judith, Pender, Michael P. and Pryce, Karena (2010). Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies. Cancer Epidemiology, Biomarkers and Prevention, 19 (3), 794-798. doi: 10.1158/1055-9965.EPI-09-0812

Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies

2009

Journal Article

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

Bahlo, Melanie, Booth, David R., Broadley, Simon A., Brown, Matthew A., Foote, Simon J., Griffiths, Lyn R., Kilpatrick, Trevour J., Lechner-Scott, Jeanette, Moscato, Pablo, Perreau, Victoria M., Rubio, Justin P., Scott, Rodney J., Stankovich, Jim, Stewart, Graeme J., Taylor, Bruce V., Wiley, James, Clarke, Glynnis, Cox, Mathew B., Csurhes, Peter A., Danoy, Patrick, Drysdale, Karen, Field, Judith, Foote, Simon J., Greer, Judith M., Griffiths, Lyn R, Hadler, Johanna, McMorran, Brendan J., Jensen, Cathy J., Johnson, Laura J. ... Willoughby, Ernest (2009). Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nature Genetics, 41 (7), 824-828. doi: 10.1038/ng.396

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20