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2020

Journal Article

Predictive nephrotoxicity profiling of a novel antifungal small molecule in comparison to amphotericin B and voriconazole

Udawatte, Nadeeka S., Kang, Sung Wook, Wang, Yue, Arumugam, Thiruma V. and Seneviratne, Chaminda J. (2020). Predictive nephrotoxicity profiling of a novel antifungal small molecule in comparison to amphotericin B and voriconazole. Frontiers in Pharmacology, 11 511. doi: 10.3389/fphar.2020.00511

Predictive nephrotoxicity profiling of a novel antifungal small molecule in comparison to amphotericin B and voriconazole

2020

Journal Article

Proteomics analysis of Candida albicans dnm1 haploid mutant unraveled the association between mitochondrial fission and antifungal susceptibility

Truong, Thuyen, Zeng, Guisheng, Lim, Teck Kwang, Cao, Tong, Pang, Li Mei, Lee, Yew Mun, Lin, Qingsong, Wang, Yue and Seneviratne, Chaminda Jayampath (2020). Proteomics analysis of Candida albicans dnm1 haploid mutant unraveled the association between mitochondrial fission and antifungal susceptibility. Proteomics, 20 (1) 1900240, 1-12. doi: 10.1002/pmic.201900240

Proteomics analysis of Candida albicans dnm1 haploid mutant unraveled the association between mitochondrial fission and antifungal susceptibility

2019

Journal Article

Machine learning and its potential applications to the genomic study of head and neck cancer—a systematic review

Patil, Shankargouda, Habib Awan, Kamran, Arakeri, Gururaj, Jayampath Seneviratne, Chaminda, Muddur, Nagaraj, Malik, Shuaib, Ferrari, Marco, Rahimi, Siavash and Brennan, Peter A. (2019). Machine learning and its potential applications to the genomic study of head and neck cancer—a systematic review. Journal of Oral Pathology and Medicine, 48 (9), 773-779. doi: 10.1111/jop.12854

Machine learning and its potential applications to the genomic study of head and neck cancer—a systematic review

2019

Journal Article

Multi-omics analyses reveal synergistic carbohydrate metabolism in Streptococcus mutans-Candida albicans mixed-species biofilms

Ellepola, K., Truong, T., Liu, Y., Lin, Q., Lim, T. K., Lee, Y. M., Cao, T., Koo, H. and Seneviratne, C. J. (2019). Multi-omics analyses reveal synergistic carbohydrate metabolism in Streptococcus mutans-Candida albicans mixed-species biofilms. Infection and Immunity, 87 (10) e00339-19, 1-20. doi: 10.1128/IAI.00339-19

Multi-omics analyses reveal synergistic carbohydrate metabolism in Streptococcus mutans-Candida albicans mixed-species biofilms

2019

Journal Article

Hydrophobicity of graphene as a driving force for inhibiting biofilm formation of pathogenic bacteria and fungi

Agarwalla, Shruti Vidhawan, Ellepola, Kassapa, Costa, Mariana Caldeira Ferraz da, Fechine, Guilhermino José Macêdo, Morin, Julien Luc Paul, Castro Neto, A. H., Seneviratne, Chaminda Jayampath and Rosa, Vinicius (2019). Hydrophobicity of graphene as a driving force for inhibiting biofilm formation of pathogenic bacteria and fungi. Dental Materials, 35 (3), 403-413. doi: 10.1016/j.dental.2018.09.016

Hydrophobicity of graphene as a driving force for inhibiting biofilm formation of pathogenic bacteria and fungi

2019

Journal Article

Periodontal commensals and pathogens differentially modulate immuno-inflammatory response in human oral keratinocytes

Li, Hua Jing, Seneviratne, Chaminda Jayampath, Wang, Cun Yu and Jin, Li Jian (2019). Periodontal commensals and pathogens differentially modulate immuno-inflammatory response in human oral keratinocytes. The Chinese Journal of Dental Research, 22 (2), 105-112. doi: 10.3290/j.cjdr.a42514

Periodontal commensals and pathogens differentially modulate immuno-inflammatory response in human oral keratinocytes

2018

Journal Article

Keystone species in pregnancy gingivitis: a snapshot of oral microbiome during pregnancy and postpartum period

Balan, Preethi, Chong, Yap Seng, Umashankar, Shivshankar, Swarup, Sanjay, Loke, Wong Mun, Lopez, Violeta, He, Hong Gu and Seneviratne, Chaminda Jayampath (2018). Keystone species in pregnancy gingivitis: a snapshot of oral microbiome during pregnancy and postpartum period. Frontiers in Microbiology, 9 (OCT) 2360, 1-11. doi: 10.3389/fmicb.2018.02360

Keystone species in pregnancy gingivitis: a snapshot of oral microbiome during pregnancy and postpartum period

2018

Journal Article

Correction: Quantitative proteomics of strong and weak biofilm formers of Enterococcus faecalis reveals novel regulators of biofilm formation (Molecular and Cellular Proteomics (2018) 17 (643-654) DOI: 10.1074/mcp.RA117.000461)

Suriyanarayanan, Tanujaa, Qingsong, Lin, Kwang, Lim Teck, Mun, Lee Yew, Truong, Thuyen and Seneviratne, Chaminda Jayampath (2018). Correction: Quantitative proteomics of strong and weak biofilm formers of Enterococcus faecalis reveals novel regulators of biofilm formation (Molecular and Cellular Proteomics (2018) 17 (643-654) DOI: 10.1074/mcp.RA117.000461). Molecular and Cellular Proteomics, 17 (10). doi: 10.1074/mcp.AAC118.001077

Correction: Quantitative proteomics of strong and weak biofilm formers of Enterococcus faecalis reveals novel regulators of biofilm formation (Molecular and Cellular Proteomics (2018) 17 (643-654) DOI: 10.1074/mcp.RA117.000461)

2018

Journal Article

Controlled cellular redox, repressive hemin utilization and adaptive stress responses are crucial to metronidazole tolerance of Porphyromonas gingivalis persisters

Li, Peng, Fung, Yi-Man Eva, Yin, Xiaohui, Seneviratne, Chaminda J., Che, Chi-Ming and Jin, Lijian (2018). Controlled cellular redox, repressive hemin utilization and adaptive stress responses are crucial to metronidazole tolerance of Porphyromonas gingivalis persisters. Journal of Clinical Periodontology, 45 (10), 1211-1221. doi: 10.1111/jcpe.13002

Controlled cellular redox, repressive hemin utilization and adaptive stress responses are crucial to metronidazole tolerance of Porphyromonas gingivalis persisters

2018

Journal Article

Oral health in pregnant Chinese women in Singapore: a call to go beyond the traditional clinical care

Balan, Preethi, He, Hong-Gu, Cao, Fengchunzhi, Wong, Mun Loke, Chong, Yap-Seng, Lopez, Violeta, Soh, Shu-E. and Seneviratne, Chaminda Jayampath (2018). Oral health in pregnant Chinese women in Singapore: a call to go beyond the traditional clinical care. Healthcare, 6 (3) 77, 1-12. doi: 10.3390/healthcare6030077

Oral health in pregnant Chinese women in Singapore: a call to go beyond the traditional clinical care

2018

Journal Article

Immunomodulation as therapy for fungal infection: are we closer?

Sam, Qi Hui, Yew, Wen Shan, Seneviratne, Chaminda J., Chang, Matthew Wook and Chai, Louis Yi Ann (2018). Immunomodulation as therapy for fungal infection: are we closer?. Frontiers in Microbiology, 9 (JUL) 1612, 1-16. doi: 10.3389/fmicb.2018.01612

Immunomodulation as therapy for fungal infection: are we closer?

2018

Journal Article

Use of haploid model of Candida albicans to uncover mechanism of action of a novel antifungal agent

Truong, Thuyen, Suriyanarayanan, Tanujaa, Zeng, Guisheng, Le, Thuc D., Liu, Lin, Li, Jiuyong, Tong, Cao, Wang, Yue and Seneviratne, Chaminda J. (2018). Use of haploid model of Candida albicans to uncover mechanism of action of a novel antifungal agent. Frontiers in Cellular and Infection Microbiology, 8 164. doi: 10.3389/fcimb.2018.00164

Use of haploid model of Candida albicans to uncover mechanism of action of a novel antifungal agent

2018

Journal Article

Is the oral fungal pathogen Candida albicans a cariogen?

Pereira, D. F. A., Seneviratne, C. J., Koga-Ito, C. Y. and Samaranayake, L. P. (2018). Is the oral fungal pathogen Candida albicans a cariogen?. Oral Diseases, 24 (4), 518-526. doi: 10.1111/odi.12691

Is the oral fungal pathogen Candida albicans a cariogen?

2018

Journal Article

Quantitative proteomics of strong and weak biofilm formers of Enterococcus faecalis reveals novel regulators of biofilm formation

Suriyanarayanan, Tanujaa, Qingsong, Lin, Kwang, Lim Teck, Mun, Lee Yew and Seneviratne, Chaminda Jayampath (2018). Quantitative proteomics of strong and weak biofilm formers of Enterococcus faecalis reveals novel regulators of biofilm formation. Molecular and Cellular Proteomics, 17 (4), 643-654. doi: 10.1074/mcp.RA117.000461

Quantitative proteomics of strong and weak biofilm formers of Enterococcus faecalis reveals novel regulators of biofilm formation

2018

Journal Article

Graphene onto medical grade titanium: an atom-thick multimodal coating that promotes osteoblast maturation and inhibits biofilm formation from distinct species

Dubey, Nileshkumar, Ellepola, Kassapa, Decroix, Fanny E. D., Morin, Julien L. P., Castro Neto, A. H., Seneviratne, Chaminda J. and Rosa, Vinicius (2018). Graphene onto medical grade titanium: an atom-thick multimodal coating that promotes osteoblast maturation and inhibits biofilm formation from distinct species. Nanotoxicology, 12 (4), 274-289. doi: 10.1080/17435390.2018.1434911

Graphene onto medical grade titanium: an atom-thick multimodal coating that promotes osteoblast maturation and inhibits biofilm formation from distinct species

2017

Journal Article

Directed differentiation of human embryonic stem cells to neural crest stem cells, functional peripheral neurons, and corneal keratocytes

Zhu, Qian, Li, Mingming, Yan, Chuan, Lu, Qiqi, Wei, Shunhui, Gao, Rong, Yu, Mengfei, Zou, Yu, Sriram, Gopu, Tong, Huei J., Hunziker, Walter, Seneviratne, Chaminda J., Gong, Zhiyuan, Olsen, Bjorn R. and Cao, Tong (2017). Directed differentiation of human embryonic stem cells to neural crest stem cells, functional peripheral neurons, and corneal keratocytes. Biotechnology Journal, 12 (12) 1700067, 1-11. doi: 10.1002/biot.201700067

Directed differentiation of human embryonic stem cells to neural crest stem cells, functional peripheral neurons, and corneal keratocytes

2017

Journal Article

Bacterial GtfB augments Candida albicans accumulation in cross-kingdom biofilms

Ellepola, K., Liu, Y., Cao, T., Koo, H. and Seneviratne, C. J. (2017). Bacterial GtfB augments Candida albicans accumulation in cross-kingdom biofilms. Journal of Dental Research, 96 (10), 1129-1135. doi: 10.1177/0022034517714414

Bacterial GtfB augments Candida albicans accumulation in cross-kingdom biofilms

2017

Journal Article

Transcriptomics analysis reveals putative genes involved in biofilm formation and biofilm-associated drug resistance of Enterococcus faecalis

Seneviratne, Chaminda J., Suriyanarayanan, Tanujaa, Swarup, Sanjay, Chia, Kuan Hui Burton, Nagarajan, Niranjan and Zhang, Chengfei (2017). Transcriptomics analysis reveals putative genes involved in biofilm formation and biofilm-associated drug resistance of Enterococcus faecalis. Journal of Endodontics, 43 (6), 949-955. doi: 10.1016/j.joen.2017.01.020

Transcriptomics analysis reveals putative genes involved in biofilm formation and biofilm-associated drug resistance of Enterococcus faecalis

2017

Journal Article

Streptococcus mutans forms xylitol-resistant biofilm on excess adhesive flash in novel ex-vivo orthodontic bracket model

Ho, Cindy S.F., Ming, Yue, Foong, Kelvin W.C., Rosa, Vinicius, Thuyen, Truong and Seneviratne, Chaminda J. (2017). Streptococcus mutans forms xylitol-resistant biofilm on excess adhesive flash in novel ex-vivo orthodontic bracket model. American Journal of Orthodontics and Dentofacial Orthopedics, 151 (4), 669-677. doi: 10.1016/j.ajodo.2016.09.017

Streptococcus mutans forms xylitol-resistant biofilm on excess adhesive flash in novel ex-vivo orthodontic bracket model

2016

Journal Article

Comparative ploidy proteomics of Candida albicans biofilms unraveled the role of the AHP1 gene in the biofilm persistence against amphotericin B

Truong, Thuyen, Zeng, Guisheng, Lin, Qingsong, Kwang, Lim Teck, Tong, Cao, Chan, Fong Yee, Wang, Yue and Seneviratne, Chaminda Jayampath (2016). Comparative ploidy proteomics of Candida albicans biofilms unraveled the role of the AHP1 gene in the biofilm persistence against amphotericin B. Molecular and Cellular Proteomics, 15 (11), 3488-3500. doi: 10.1074/mcp.M116.061523

Comparative ploidy proteomics of Candida albicans biofilms unraveled the role of the AHP1 gene in the biofilm persistence against amphotericin B