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2024 Journal Article Embracing computational immunologyCañete, Pablo F and Tuong, Zewen Kelvin (2024). Embracing computational immunology. Immunology & Cell Biology, 102 (8), 663-664. doi: 10.1111/imcb.12817 |
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2024 Journal Article Computational estimation of clonal diversity in autoimmunityTuong, Zewen Kelvin, van der Merwe, Rohan, Canete, Pablo F and Roco, Jonathan A (2024). Computational estimation of clonal diversity in autoimmunity. Immunology and Cell Biology, 102 (8), 692-701. doi: 10.1111/imcb.12801 |
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2024 Journal Article Follicular T cells and the control of IgE responsesCañete, Pablo F. and Yu, Di (2024). Follicular T cells and the control of IgE responses. Allergology International, 74 (1), 13-19. doi: 10.1016/j.alit.2024.09.007 |
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2023 Journal Article DECTIN-1: a modifier protein in CTLA-4 haploinsufficiencyTurnbull, Cynthia, Bones, Josiah, Stanley, Maurice, Medhavy, Arti, Wang, Hao, Lorenzo, Ayla May D., Cappello, Jean, Shanmuganandam, Somasundhari, Pandey, Abhimanu, Seneviratne, Sandali, Brown, Grant J., Meng, Xiangpeng, Fulcher, David, Burgio, Gaetan, Man, Si Ming, de Lucas Collantes, Carmen, Gasior, Mercedes, López Granados, Eduardo, Martin, Pilar, Jiang, Simon H., Cook, Matthew C., Ellyard, Julia I., Athanasopoulos, Vicki, Corry, Ben, Canete, Pablo F. and Vinuesa, Carola G. (2023). DECTIN-1: a modifier protein in CTLA-4 haploinsufficiency. Science Advances, 9 (49) eadi9566, 1-14. doi: 10.1126/sciadv.adi9566 |
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2023 Journal Article Systemic immunometabolism and responses to vaccines: insights from T and B cell perspectivesNettelfield, Sam, Yu, Di and Cañete, Pablo F (2023). Systemic immunometabolism and responses to vaccines: insights from T and B cell perspectives. International Immunology, 35 (12), 571-582. doi: 10.1093/intimm/dxad021 |
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2023 Journal Article CTLA4 protects against maladaptive cytotoxicity during the differentiation of effector and follicular CD4+ T cellsHao, Yuwei, Miraghazadeh, Bahar, Chand, Rochna, Davies, Ainsley R., Cardinez, Chelisa, Kwong, Kristy, Downes, Morgan B., Sweet, Rebecca A., Cañete, Pablo F., D’Orsogna, Lloyd J., Fulcher, David A., Choo, Sharon, Yip, Desmond, Peters, Geoffrey, Yip, Sonia, Witney, Matthew J., Nekrasov, Maxim, Feng, Zhi-Ping, Tscharke, David C., Vinuesa, Carola G. and Cook, Matthew C. (2023). CTLA4 protects against maladaptive cytotoxicity during the differentiation of effector and follicular CD4+ T cells. Cellular and Molecular Immunology, 20 (7), 1-17. doi: 10.1038/s41423-023-01027-8 |
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2023 Journal Article Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiationChen, Zhian, Cui, Yanfang, Yao, Yin, Liu, Bo, Yunis, Joseph, Gao, Xin, Wang, Naiqi, Cañete, Pablo F., Tuong, Zewen Kelvin, Sun, Hongjian, Wang, Hao, Yang, Siling, Wang, Runli, Leong, Yew Ann, Simon Davis, David, Qin, Jiahuan, Liang, Kaili, Deng, Jun, Wang, Conan K., Huang, Yen-Hua, Roco, Jonathan A., Nettelfield, Sam, Zhu, Huaming, Xu, Huajun, Yu, Zhijia, Craik, David, Liu, Zheng, Qi, Hai, Parish, Christopher and Yu, Di (2023). Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology, 8 (80) eadd1728, 1-17. doi: 10.1126/sciimmunol.add1728 |
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2022 Journal Article Extrafollicular plasmablasts present in the acute phase of infections express high levels of PD-L1 and are able to limit T cell responseSerrán, Melisa Gorosito, Vernengo, Facundo Fiocca, Almada, Laura, Beccaria, Cristian G., Gazzoni, Yamila, Canete, Pablo F., Roco, Jonathan A., Boari, Jimena Tosello, Ramello, Maria Cecilia, Wehrens, Ellen, Cai, Yeping, Zuniga, Elina I., Montes, Carolina L., Cockburn, Ian A., Rodriguez, Eva V. Acosta, Vinuesa, Carola G. and Gruppi, Adriana (2022). Extrafollicular plasmablasts present in the acute phase of infections express high levels of PD-L1 and are able to limit T cell response. Frontiers in Immunology, 13 828734, 1-13. doi: 10.3389/fimmu.2022.828734 |
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2022 Journal Article TLR7 gain-of-function genetic variation causes human lupusBrown, Grant J., Cañete, Pablo F., Wang, Hao, Medhavy, Arti, Bones, Josiah, Roco, Jonathan A., He, Yuke, Qin, Yuting, Cappello, Jean, Ellyard, Julia I., Bassett, Katharine, Shen, Qian, Burgio, Gaetan, Zhang, Yaoyuan, Turnbull, Cynthia, Meng, Xiangpeng, Wu, Phil, Cho, Eun, Miosge, Lisa A., Andrews, T. Daniel, Field, Matt A., Tvorogov, Denis, Lopez, Angel F., Babon, Jeffrey J., López, Cristina Aparicio, Gónzalez-Murillo, África, Garulo, Daniel Clemente, Pascual, Virginia, Levy, Tess ... Vinuesa, Carola G. (2022). TLR7 gain-of-function genetic variation causes human lupus. Nature, 605 (7909), 349-356. doi: 10.1038/s41586-022-04642-z |
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2022 Journal Article Evolution of γ chain cytokines: mechanisms, methods and applicationsAntczak, Magdalena, Cañete, Pablo F., Chen, Zhian, Belle, Clémence and Yu, Di (2022). Evolution of γ chain cytokines: mechanisms, methods and applications. Computational and Structural Biotechnology Journal, 20, 4746-4755. doi: 10.1016/j.csbj.2022.08.050 |
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2021 Journal Article Deletions in VANGL1 are a risk factor for antibody-mediated kidney diseaseJiang, Simon H., Mercan, Sevcan, Papa, Ilenia, Moldovan, Max, Walters, Giles D., Koina, Mark, Fadia, Mitali, Stanley, Maurice, Lea-Henry, Tom, Cook, Amelia, Ellyard, Julia, McMorran, Brendan, Sundaram, Madhivanan, Thomson, Russell, Canete, Pablo F., Hoy, Wendy, Hutton, Holly, Srivastava, Monika, McKeon, Kathryn, de la Rúa Figueroa, Iñigo, Cervera, Ricard, Faria, Raquel, D'Alfonso, Sandra, Gatto, Mariele, Athanasopoulos, Vicki, Field, Matthew, Mathews, John, Cho, Eun, Andrews, Thomas D. ... Vinuesa, Carola G. (2021). Deletions in VANGL1 are a risk factor for antibody-mediated kidney disease. Cell Reports Medicine, 2 (12) 100475, 100475. doi: 10.1016/j.xcrm.2021.100475 |
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2021 Journal Article Follicular regulatory T cells produce neuritin to regulate B cellsGonzalez-Figueroa, Paula, Roco, Jonathan A., Papa, Ilenia, Núñez Villacís, Lorena, Stanley, Maurice, Linterman, Michelle A., Dent, Alexander, Canete, Pablo F. and Vinuesa, Carola G. (2021). Follicular regulatory T cells produce neuritin to regulate B cells. Cell, 184 (7), 1775-1789.e19. doi: 10.1016/j.cell.2021.02.027 |
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2020 Journal Article COVID-19 Makes B Cells Forget, but T Cells RememberCañete, Pablo F. and Vinuesa, Carola G. (2020). COVID-19 Makes B Cells Forget, but T Cells Remember. Cell, 183 (1), 13-15. doi: 10.1016/j.cell.2020.09.013 |
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2019 Journal Article Class-switch recombination occurs infrequently in germinal centersRoco, Jonathan A., Mesin, Luka, Binder, Sebastian C., Nefzger, Christian, Gonzalez-Figueroa, Paula, Canete, Pablo F., Ellyard, Julia, Shen, Qian, Robert, Philippe A., Cappello, Jean, Vohra, Harpreet, Zhang, Yang, Nowosad, Carla R., Schiepers, Arien, Corcoran, Lynn M., Toellner, Kai-Michael, Polo, Jose M., Meyer-Hermann, Michael, Victora, Gabriel D. and Vinuesa, Carola G. (2019). Class-switch recombination occurs infrequently in germinal centers. Immunity, 51 (2), 337-350.e7. doi: 10.1016/j.immuni.2019.07.001 |
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2019 Journal Article Regulatory roles of IL-10–producing human follicular T cellsCañete, Pablo F., Sweet, Rebecca A., Gonzalez-Figueroa, Paula, Papa, Ilenia, Ohkura, Naganari, Bolton, Holly, Roco, Jonathan A., Cuenca, Marta, Bassett, Katharine J., Sayin, Ismail, Barry, Emma, Lopez, Angel, Canaday, David H., Meyer-Hermann, Michael, Doglioni, Claudio, Fazekas de St Groth, Barbara, Sakaguchi, Shimon, Cook, Matthew C. and Vinuesa, Carola G. (2019). Regulatory roles of IL-10–producing human follicular T cells. Journal of Experimental Medicine, 216 (8), 1843-1856. doi: 10.1084/jem.20190493 |
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2019 Journal Article Functional rare and low frequency variants in BLK and BANK1 contribute to human lupusJiang, Simon H., Athanasopoulos, Vicki, Ellyard, Julia I., Chuah, Aaron, Cappello, Jean, Cook, Amelia, Prabhu, Savit B., Cardenas, Jacob, Gu, Jinghua, Stanley, Maurice, Roco, Jonathan A., Papa, Ilenia, Yabas, Mehmet, Walters, Giles D., Burgio, Gaetan, McKeon, Kathryn, Byers, James M., Burrin, Charlotte, Enders, Anselm, Miosge, Lisa A., Canete, Pablo F., Jelusic, Marija, Tasic, Velibor, Lungu, Adrian C., Alexander, Stephen I., Kitching, Arthur R., Fulcher, David A., Shen, Nan, Arsov, Todor ... Vinuesa, Carola G. (2019). Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus. Nature Communications, 10 (1) 2201. doi: 10.1038/s41467-019-10242-9 |
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2017 Journal Article TFH-derived dopamine accelerates productive synapses in germinal centresPapa, Ilenia, Saliba, David, Ponzoni, Maurilio, Bustamante, Sonia, Canete, Pablo F., Gonzalez-Figueroa, Paula, McNamara, Hayley A., Valvo, Salvatore, Grimbaldeston, Michele, Sweet, Rebecca A., Vohra, Harpreet, Cockburn, Ian A., Meyer-Hermann, Michael, Dustin, Michael L., Doglioni, Claudio and Vinuesa, Carola G. (2017). TFH-derived dopamine accelerates productive synapses in germinal centres. Nature, 547 (7663), 318-323. doi: 10.1038/nature23013 |
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2017 Journal Article IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2Jandl, Christoph, Liu, Sue M., Cañete, Pablo F., Warren, Joanna, Hughes, William E., Vogelzang, Alexis, Webster, Kylie, Craig, Maria E., Uzel, Gulbu, Dent, Alexander, Stepensky, Polina, Keller, Bärbel, Warnatz, Klaus, Sprent, Jonathan and King, Cecile (2017). IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2. Nature Communications, 8 (1) 14647. doi: 10.1038/ncomms14647 |
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2015 Journal Article Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formationRamiscal, Roybel R, Parish, Ian A, Lee-Young, Robert S, Babon, Jeffrey J, Blagih, Julianna, Pratama, Alvin, Martin, Jaime, Hawley, Naomi, Cappello, Jean Y, Nieto, Pablo F, Ellyard, Julia I, Kershaw, Nadia J, Sweet, Rebecca A, Goodnow, Christopher C, Jones, Russell G, Febbraio, Mark A, Vinuesa, Carola G and Athanasopoulos, Vicki (2015). Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation. eLife, 4 (OCTOBER2015) 08698, 1-22. doi: 10.7554/elife.08698 |
