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2024

Journal Article

Analysis of three characterization assays reveals ddPCR of LIN28A as the most sensitive for the detection of residual pluripotent stem cells in cellular therapy products

Sun, Jinda, Yates, Clarissa, Dingwall, Steve, Ongtengco, Cherica, Power, Dominique, Gray, Peter and Prowse, Andrew (2024). Analysis of three characterization assays reveals ddPCR of LIN28A as the most sensitive for the detection of residual pluripotent stem cells in cellular therapy products. Cytotherapy, 26 (11), 1374-1381. doi: 10.1016/j.jcyt.2024.05.019

Analysis of three characterization assays reveals ddPCR of LIN28A as the most sensitive for the detection of residual pluripotent stem cells in cellular therapy products

2024

Journal Article

Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

Selvakumar, Dinesh, Clayton, Zoe E., Prowse, Andrew, Dingwall, Steve, Kim, Sul Ki, Reyes, Leila, George, Jacob, Shah, Haisam, Chen, Siqi, Leung, Halina H. L., Hume, Robert D., Tjahjadi, Laurentius, Igoor, Sindhu, Skelton, Rhys J. P., Hing, Alfred, Paterson, Hugh, Foster, Sheryl L., Pearson, Lachlan, Wilkie, Emma, Marcus, Alan D., Jeyaprakash, Prajith, Wu, Zhixuan, Chiu, Han Shen, Ongtengco, Cherica Felize J., Mulay, Onkar, McArthur, Jeffrey R., Barry, Tony, Lu, Juntang, Tran, Vu ... Chong, James J. H. (2024). Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias. Nature Cardiovascular Research, 3 (2), 145-165. doi: 10.1038/s44161-023-00419-3

Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

2016

Journal Article

Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage

Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C. Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage. Journal of Leukocyte Biology, 101 (4), 927-947. doi: 10.1189/jlb.4VMA0716-316R

Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage

2016

Journal Article

A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype

Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L. and Lavin, Martin F. (2016). A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype. Human Molecular Genetics, 26 (1), 109-123. doi: 10.1093/hmg/ddw371

A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype

2015

Journal Article

Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells

Dingwall, Steve, Lee, Jung Bok, Guezguez, Borhane, Fiebig, Aline, McNicol, Jamie, Boreham, Douglas, Collins, Tony J. and Bhatia, Mick (2015). Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells. Oncotarget, 6 (26), 22258-22269. doi: 10.18632/oncotarget.4165

Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells

2015

Journal Article

Cellular reprogramming allows generation of autologous hematopoietic progenitors from AML patients that are devoid of patient-specific genomic aberrations

Salci, Kyle R., Lee, Jong-Hee, Laronde, Sarah, Dingwall, Steve, Kushwah, Rahul, Fiebig-Comyn, Aline, Leber, Brian, Foley, Ronan, Dal Cin, Arianna and Bhatia, Mickie (2015). Cellular reprogramming allows generation of autologous hematopoietic progenitors from AML patients that are devoid of patient-specific genomic aberrations. Stem Cells, 33 (6), 1839-49. doi: 10.1002/stem.1994

Cellular reprogramming allows generation of autologous hematopoietic progenitors from AML patients that are devoid of patient-specific genomic aberrations

2015

Journal Article

Expression of Histocompatibility 2 Blastocyst (H2-Bl) in embryonic stem cells inhibits CD8+ T-cell activation but is not sufficient to facilitate graft tolerance

Dingwall, Steven, Brooks, Andrew, Apte, Simon H., Waters, Mike, Lavin, Martin F. and Wolvetang, Ernst J. (2015). Expression of Histocompatibility 2 Blastocyst (H2-Bl) in embryonic stem cells inhibits CD8+ T-cell activation but is not sufficient to facilitate graft tolerance. Journal of Stem Cell Research and Therapy, 5 (12) 1000320, 1-8. doi: 10.4172/2157-7633.1000320

Expression of Histocompatibility 2 Blastocyst (H2-Bl) in embryonic stem cells inhibits CD8+ T-cell activation but is not sufficient to facilitate graft tolerance

2011

Journal Article

Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease

Risueño, Ruth M, Campbell, Clinton J V, Dingwall, Steve, Levadoux-Martin, Marilyne, Leber, Brian, Xenocostas, Anargyros and Bhatia, Mickie (2011). Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease. Blood, 117 (26), 7112-7120. doi: 10.1182/blood-2011-01-329078

Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease

2011

Journal Article

Human health and the biological effects of tritium in drinking water: Prudent policy through science - Addressing the ODWAC new recommendation

Dingwall, S., Mills, C. E., Phan, N., Taylor, K. and Boreham, D. R. (2011). Human health and the biological effects of tritium in drinking water: Prudent policy through science - Addressing the ODWAC new recommendation. Dose-Response, 9 (1), 6-31. doi: 10.2203/dose-response.10-048.Boreham

Human health and the biological effects of tritium in drinking water: Prudent policy through science - Addressing the ODWAC new recommendation

2009

Journal Article

Characterization of human embryonic stem cells with features of neoplastic progression

Werbowetski-Ogilvie, Tamra E, Bossé, Marc, Stewart, Morag, Schnerch, Angelique, Ramos-Mejia, Veronica, Rouleau, Anne, Wynder, Tracy, Smith, Mary-Jo, Dingwall, Steve, Carter, Tim, Williams, Christopher, Harris, Charles, Dolling, Joanna, Wynder, Christopher, Boreham, Doug and Bhatia, Mickie (2009). Characterization of human embryonic stem cells with features of neoplastic progression. Nature Biotechnology, 27 (1), 91-7. doi: 10.1038/nbt.1516

Characterization of human embryonic stem cells with features of neoplastic progression