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2024 Journal Article Multifunctional fluoropolymer‐engineered magnetic nanoparticles to facilitate blood‐brain barrier penetration and effective gene silencing in medulloblastomaForgham, Helen, Zhu, Jiayuan, Huang, Xumin, Zhang, Cheng, Biggs, Heather, Liu, Liwei, Wang, Yi Cheng, Fletcher, Nicholas, Humphries, James, Cowin, Gary, Mardon, Karine, Kavallaris, Maria, Thurecht, Kristofer, Davis, Thomas P. and Qiao, Ruirui (2024). Multifunctional fluoropolymer‐engineered magnetic nanoparticles to facilitate blood‐brain barrier penetration and effective gene silencing in medulloblastoma. Advanced Science, 11 (25) 2401340, e2401340. doi: 10.1002/advs.202401340 |
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2023 Journal Article Spiky silver–iron oxide nanohybrid for effective dual-imaging and synergistic thermo-chemotherapyMoonshi, Shehzahdi S., Vazquez-Prada, Karla X., Tang, Joyce, Westra van Holthe, Nicholas J., Cowin, Gary, Wu, Yuao, Tran, Huong D. N., Mckinnon, Ryan, Bulmer, Andrew C. and Ta, Hang Thu (2023). Spiky silver–iron oxide nanohybrid for effective dual-imaging and synergistic thermo-chemotherapy. ACS Applied Materials and Interfaces, 15 (36), 42153-42169. doi: 10.1021/acsami.3c04696 |
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2023 Journal Article Synthesis and preclinical evaluation of fluorinated 5-azaindoles as CB2 PET radioligandsKallinen, Annukka, Mardon, Karine, Lane, Samuel, Montgomery, Andrew P., Bhalla, Rajiv, Stimson, Damion H. R., Ahamed, Muneer, Cowin, Gary J., Hibbs, David, Werry, Eryn L., Fulton, Roger, Connor, Mark and Kassiou, Michael (2023). Synthesis and preclinical evaluation of fluorinated 5-azaindoles as CB2 PET radioligands. ACS Chemical Neuroscience, 14 (16), 2902-2921. doi: 10.1021/acschemneuro.3c00345 |
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2023 Journal Article Multi-parametric MR for detection of pathological changes in CNS of mouse model of multiple sclerosis in vivoAlthobity, Abdullah A., Khan, Nemat, Sandrock, Cheyenne J., Woodruff, Trent M, Cowin, Gary J., Brereton, Ian M. and Kurniawan, Nyoman D. (2023). Multi-parametric MR for detection of pathological changes in CNS of mouse model of multiple sclerosis in vivo. NMR in Biomedicine, 36 (10) e4964, e4964. doi: 10.1002/nbm.4964 |
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2023 Journal Article Gold-iron oxide nanoparticle: A unique multimodal theranostic approach for thrombosisFithri, Najma Annuria, Wu, Yuao, Cowin, Gary, Akhter, Fahima, Tran, Huong D.N., Tse, Brian, van Holthe, Nicholas Westra, Moonshi, Shehzahdi S., Peter, Karlheinz, Wang, Xiaowei, Truong, Nghia P. and Ta, Hang Thu (2023). Gold-iron oxide nanoparticle: A unique multimodal theranostic approach for thrombosis. Applied Materials Today, 31 101750, 1-14. doi: 10.1016/j.apmt.2023.101750 |
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2022 Journal Article Utilizing PET and MALDI imaging for discovery of a targeted probe for brain endocannabinoid α/β-hydrolase domain 6 (ABHD6)Mardon, Karine, Patel, Jayendra Z., Savinainen, Juha R., Stimson, Damion H. R., Oyagawa, Caitlin R. M., Grimsey, Natasha L., Migotto, Mary-anne, Njiru, Grace F. M., Hamilton, Brett R., Cowin, Gary, Yli-Kauhaluoma, Jari, Vanduffel, Wim, Blakey, Idriss, Bhalla, Rajiv, Cawthorne, Christopher, Celen, Sofie, Bormans, Guy, Thurecht, Kristofer J and Ahamed, Muneer (2022). Utilizing PET and MALDI imaging for discovery of a targeted probe for brain endocannabinoid α/β-hydrolase domain 6 (ABHD6). Journal of Medicinal Chemistry, 66 (1), 538-552. doi: 10.1021/acs.jmedchem.2c01485 |
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2022 Journal Article Magnetic resonance imaging anatomy of the craniovertebral ligaments: a radiological study with confirmatory dissectionOsmotherly, Peter Grant, Cowin, Gary J. and Rivett, Darren A. (2022). Magnetic resonance imaging anatomy of the craniovertebral ligaments: a radiological study with confirmatory dissection. Journal of Craniovertebral Junction and Spine, 13 (3), 309-317. doi: 10.4103/jcvjs.jcvjs_62_22 |
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2022 Journal Article Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruptionJanowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J. and Thurecht, Kristofer J. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283 121416, 121416. doi: 10.1016/j.biomaterials.2022.121416 |
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2022 Journal Article Simultaneous dual echo gadolinium enhanced MR-PET for evaluation of PET tracer delivery in altered pathophysiologyCowin, Gary J, Mardon, Karine, Houston, Zachary H., Bhalla, Rajiv, Stimson, Damion H. R., Thurecht, Kristofer J. and Brereton, Ian M. (2022). Simultaneous dual echo gadolinium enhanced MR-PET for evaluation of PET tracer delivery in altered pathophysiology. Frontiers in Physics, 10 759749. doi: 10.3389/fphy.2022.759749 |
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2022 Journal Article Neurovascular unit alterations in the growth-restricted newborn are improved following Ibuprofen treatmentChand, Kirat K., Miller, Stephanie M., Cowin, Gary J., Mohanty, Lipsa, Pienaar, Jany, Colditz, Paul B., Bjorkman, Stella Tracey and Wixey, Julie A. (2022). Neurovascular unit alterations in the growth-restricted newborn are improved following Ibuprofen treatment. Molecular Neurobiology, 59 (2), 1018-1040. doi: 10.1007/s12035-021-02654-w |
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2021 Journal Article Engineering chitosan nano-cocktail containing iron oxide and ceria: a two-in-one approach for treatment of inflammatory diseases and tracking of material deliveryWu, Yuao, Cowin, Gary, Moonshi, Shehzahdi S., Tran, Huong D.N., Fithri, Najma Annuria, Whittaker, Andrew K., Zhang, Run and Ta, Hang T. (2021). Engineering chitosan nano-cocktail containing iron oxide and ceria: a two-in-one approach for treatment of inflammatory diseases and tracking of material delivery. Materials Science and Engineering C, 131 112477, 1-15. doi: 10.1016/j.msec.2021.112477 |
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2021 Journal Article A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesityPatkar, Omkar L., Mohamed, Abdalla Z., Narayanan, Ashwin, Mardon, Karine, Cowin, Gary, Bhalla, Rajiv, Stimson, Damion H. R., Kassiou, Michael, Beecher, Kate, Belmer, Arnauld, Alvarez Cooper, Ignatius, Morgan, Michael, Hume, David A., Irvine, Katharine M., Bartlett, Selena E., Nasrallah, Fatima and Cumming, Paul (2021). A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesity. Scientific Reports, 11 (1) 11252, 11252. doi: 10.1038/s41598-021-90817-z |
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2021 Journal Article Anatomy of the lumbar interspinous ligament: findings relevant to epidural insertion using loss of resistanceLawrence, Sue, Llewellyn, Stacey, Hunt, Helen, Cowin, Gary, Sturgess, David J. and Reutens, David (2021). Anatomy of the lumbar interspinous ligament: findings relevant to epidural insertion using loss of resistance. Regional Anesthesia and Pain Medicine, 46 (12), rapm-2021. doi: 10.1136/rapm-2021-103014 |
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2021 Journal Article The pharmacokinetics of PEGylated liposomal doxorubicin are not significantly affected by sex in rats or humans, but may be affected by immune dysfunctionSubasic, Christopher N., Kuilamu, Esther, Cowin, Gary, Minchin, Rodney F. and Kaminskas, Lisa M. (2021). The pharmacokinetics of PEGylated liposomal doxorubicin are not significantly affected by sex in rats or humans, but may be affected by immune dysfunction. Journal of Controlled Release, 337, 71-80. doi: 10.1016/j.jconrel.2021.07.006 |
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2021 Journal Article Airway closure is the predominant physiological mechanism of low ventilation seen on hyperpolarized helium-3 MRI lung scansNilsen, Kris, Thompson, Bruce R., Zajakovski, Natalie, Kean, Michael, Harris, Benjamin, Cowin, Gary, Robinson, Phil, Kim Prisk, G. and Thien, Francis (2021). Airway closure is the predominant physiological mechanism of low ventilation seen on hyperpolarized helium-3 MRI lung scans. Journal of Applied Physiology, 130 (3), 781-791. doi: 10.1152/JAPPLPHYSIOL.00163.2020 |
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2021 Journal Article Magnetic resonance spectroscopy assessment of brain metabolite concentrations in individuals with chronic whiplash associated disorder: a cross-sectional studyFarrell, Scott F., Cowin, Gary J., Pedler, Ashley, Durbridge, Gail, de Zoete, Rutger M. J. and Sterling, Michele (2021). Magnetic resonance spectroscopy assessment of brain metabolite concentrations in individuals with chronic whiplash associated disorder: a cross-sectional study. The Clinical Journal of Pain, 37 (1), 28-37. doi: 10.1097/ajp.0000000000000890 |
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2020 Journal Article Cetuximab exhibits sex differences in lymphatic exposure after intravenous administration in rats in the absence of differences in plasma exposureKuilamu, Esther, Subasic, Christopher, Cowin, Gary J., Simpson, Fiona, Minchin, Rodney F. and Kaminskas, Lisa M. (2020). Cetuximab exhibits sex differences in lymphatic exposure after intravenous administration in rats in the absence of differences in plasma exposure. Pharmaceutical Research, 37 (11) 224, 1-12. doi: 10.1007/s11095-020-02945-2 |
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2020 Journal Article GABAa receptor density alterations revealed in a mouse model of early moderate prenatal ethanol exposure using [18F]AH114726Nguyen, Van T., Bhalla, Rajiv, Cowin, Gary, Stimson, Damion H.R., Song, Xin, Chong, Suyinn, Jackson, Alexander, Trigg, William J., Tieng, Quang M., Mardon, Karine, Galloway, Graham J. and Kurniawan, Nyoman D. (2020). GABAa receptor density alterations revealed in a mouse model of early moderate prenatal ethanol exposure using [18F]AH114726. Nuclear Medicine and Biology, 88-89, 44-51. doi: 10.1016/j.nucmedbio.2020.07.005 |
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2020 Journal Article Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodiesHouston, Zachary H., Bunt, Jens, Chen, Kok-Siong, Puttick, Simon, Howard, Christopher B., Fletcher, Nicholas L., Fuchs, Adrian V., Cui, Jiwei, Ju, Yi, Cowin, Gary, Song, Xin, Boyd, Andrew W., Mahler, Stephen M., Richards, Linda J., Caruso, Frank and Thurecht, Kristofer J. (2020). Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies. ACS Central Science, 6 (5) acscentsci.9b01299, 727-738. doi: 10.1021/acscentsci.9b01299 |
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2020 Journal Article Temporally altered miRNA expression in a piglet model of hypoxic ischemic brain injuryCasey, Sophie, Goasdoue, Kate, Miller, Stephanie M., Brennan, Gary P., Cowin, Gary, O’Mahony, Adam G., Burke, Christopher, Hallberg, Boubou, Boylan, Geraldine B., Sullivan, Aideen M., Henshall, David C., O’Keeffe, Gerard W., Mooney, Catherine, Bjorkman, Tracey and Murray, Deirdre M. (2020). Temporally altered miRNA expression in a piglet model of hypoxic ischemic brain injury. Molecular Neurobiology, 57 (10), 4322-4344. doi: 10.1007/s12035-020-02018-w |
