Professor Nick Shaw
Professor

Nick Shaw

Email: 
Phone: 
+61 7 334 65305

Background

Nick Shaw was appointed to the School as Professor in January 2004 and undertook the role of Head of School of Pharmacy at UQ from 1st July 2004 until 31st December 2014. Nick is a pharmacist, graduating PhD from the University of Manchester in 1985 and was a member of the academic staff of the University of Nottingham from 1985-2003. He was appointed a Fellow of the Royal Society of Chemistry in 1994 and a Fellow of the Royal Pharmaceutical Society in 2010. He previously founded and chaired the Council of Pharmacy Schools (Australia and New Zealand); he is the chair of the APC Accreditation Committee and was the chair of the Australian Pharmacy Liaison Forum in 2011. He has taught across a range of subjects to the second and third years of the BPharm (Hons) course at UQ. Nick has supervised and co-supervised over 45 PhD and research Masters students.

In 2013 Nick was awarded the Pharmaceutical Society of Australia’s Bowl of Hygeia for services to the profession.

Availability

Professor Nick Shaw is:
Available for supervision

Fields of research

Analytical chemistry Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Science, The University of Manchester
  • Doctor of Philosophy, The University of Manchester
  • Fellow, Royal Pharmaceutical Society of Great Britain, Royal Pharmaceutical Society of Great Britain
  • Fellow, Royal Society of Chemistry, Royal Society of Chemistry

Research interests

  • Application of a range of analytical methodologies to solve clinical and health-related problems

  • Metabolite profiling methodology applied to nutrient profiles of tropical and other plants and secondary metabolite identification and quantitation from bacteria

  • Drug metabolism, biopharmaceutics, drug delivery and pharmacokinetic studies

Search Professor Nick Shaw’s works on UQ eSpace

295 works between 1980 and 2023
All (295) Journal Article (206) Book Chapter (1) Conference Publication (86) Other Outputs (2)

41 - 60 of 295 works

2017

Conference Publication

Bioactivity in Australian native willow: comparative analysis of leaf extracts on cell viability

Patil, A., Fitzgerald, M., Shaw, Paul N. and Parat, M. O. (2017). Bioactivity in Australian native willow: comparative analysis of leaf extracts on cell viability. International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, Switzerland, 3-7 September 2017. Stuttgart, Germany: Georg Thieme Verlag KG. doi: 10.1055/s-0037-1608430

Bioactivity in Australian native willow: comparative analysis of leaf extracts on cell viability

2017

Conference Publication

Screening of parameters affecting supercritical CO2 extraction of freeze-dried leaf juice of Carica papaya

Khaw, Kooi Yeong, Parat, Marie-Odile, Shaw, Paul N. and Falconer, James R. (2017). Screening of parameters affecting supercritical CO2 extraction of freeze-dried leaf juice of Carica papaya. Drug Delivery Australia (DDA), Wollongong, NSW Australia, 23-24 October 2017.

Screening of parameters affecting supercritical CO2 extraction of freeze-dried leaf juice of Carica papaya

2017

Journal Article

The development of a rapid, simple and sensitive LC-MS/MS method, to guide clinical dosing, for the analysis of 5-fluorouracil in human plasma

He, Wenxuan, Martin, Jennifer H., Shaw, P. Nicholas, Walpole, Euan T. and Dimeski, Goce (2017). The development of a rapid, simple and sensitive LC-MS/MS method, to guide clinical dosing, for the analysis of 5-fluorouracil in human plasma. Current Pharmaceutical Analysis, 13 (4), 378-383. doi: 10.2174/1573412912666160811114339

The development of a rapid, simple and sensitive LC-MS/MS method, to guide clinical dosing, for the analysis of 5-fluorouracil in human plasma

2016

Journal Article

Deep sequencing of the 16S ribosomal RNA of the neonatal oral microbiome: a comparison of breast-fed and formula-fed infants

Al-Shehri, S. S., Sweeney, E. L., Cowley, D. M., Liley, H. G., Ranasinghe, P. D., B. G. Charles,, Shaw, P. N., Vagenas, D., Duley, J. A. and Knox, C. L. (2016). Deep sequencing of the 16S ribosomal RNA of the neonatal oral microbiome: a comparison of breast-fed and formula-fed infants. Scientific Reports, 6 (1) 38309, 38309. doi: 10.1038/srep38309

Deep sequencing of the 16S ribosomal RNA of the neonatal oral microbiome: a comparison of breast-fed and formula-fed infants

2016

Journal Article

Global metabolite analysis of the land snail Theba pisana hemolymph during active and aestivated states

Bose, U., Centurion, E., Hodson, M. P., Shaw, P. N., Storey, K. B. and Cummins, S. F. (2016). Global metabolite analysis of the land snail Theba pisana hemolymph during active and aestivated states. Comparative Biochemistry and Physiology. Part D: Genomics and Proteomics, 19, 25-33. doi: 10.1016/j.cbd.2016.05.004

Global metabolite analysis of the land snail Theba pisana hemolymph during active and aestivated states

2016

Journal Article

To investigate the effect of the pasteurisation process on trace elements in donor breast milk

Taufek, Nor Mohd, Cartwright, David, Hewavitharana, Amitha, Koorts, Pieter, McConachy, Helen, Shaw, Nick, Whitfield, Karen and Davies, Mark (2016). To investigate the effect of the pasteurisation process on trace elements in donor breast milk. e ADC, 101 (9), A13-A14. doi: 10.1136/archdischild-2016-311535.27

To investigate the effect of the pasteurisation process on trace elements in donor breast milk

2016

Conference Publication

Effect of pasteurisation on the concentrations of vitamin D compounds in donor breast milk

Gomes, Fabio, Shaw, Nick, Whitfield, Karen, Koorts, Pieter, McConachy, Helen and Hewavitharana, Amitha (2016). Effect of pasteurisation on the concentrations of vitamin D compounds in donor breast milk. Neonatal and Paediatric Pharmacists Group (NPPG) 21st Annual Conference, London, United Kingdom, 6–8 November 2015. London, United Kingdom: BMJ Group. doi: 10.1136/archdischild-2016-311535.26

Effect of pasteurisation on the concentrations of vitamin D compounds in donor breast milk

2016

Journal Article

Anti-inflammatory and immunomodulatory properties of Carica papaya

Pandey, Saurabh, Cabot, Peter J., Shaw, P. Nicholas and Hewavitharana, Amitha K. (2016). Anti-inflammatory and immunomodulatory properties of Carica papaya. Journal of Immunotoxicology, 13 (4), 590-602. doi: 10.3109/1547691X.2016.1149528

Anti-inflammatory and immunomodulatory properties of Carica papaya

2016

Journal Article

The effect of pasteurization on trace elements in donor breast milk

Mohd-Taufek, N., Cartwright, D., Davies, M., Hewavitharana, A. K., Koorts, P., McConachy, H., Shaw, P. N., Sumner, R. and Whitfield, K. (2016). The effect of pasteurization on trace elements in donor breast milk. Journal of Perinatology, 36 (10), 897-900. doi: 10.1038/jp.2016.88

The effect of pasteurization on trace elements in donor breast milk

2016

Journal Article

Metal chelation, radical scavenging and inhibition of Aβ42 fibrillation by food constituents in relation to Alzheimer's disease

Chan, Stephen, Kantham, Srinivas, Rao, Venkatesan M., Palanivelu, Manoj Kumar, Pham, Hoang L., Shaw, P. Nicholas, McGeary, Ross P. and Ross, Benjamin P. (2016). Metal chelation, radical scavenging and inhibition of Aβ42 fibrillation by food constituents in relation to Alzheimer's disease. Food Chemistry, 199, 185-194. doi: 10.1016/j.foodchem.2015.11.118

Metal chelation, radical scavenging and inhibition of Aβ42 fibrillation by food constituents in relation to Alzheimer's disease

2016

Journal Article

Dynorphin 1-17 and Its N-Terminal Biotransformation Fragments Modulate Lipopolysaccharide-Stimulated Nuclear Factor-kappa B Nuclear Translocation, Interleukin-1beta and Tumor Necrosis Factor-alpha in Differentiated THP-1 Cells

Fazalul Rahiman, Siti Sarah, Morgan, Michael, Gray, Paul, Shaw, Paul Nicholas and Cabot, Peter John (2016). Dynorphin 1-17 and Its N-Terminal Biotransformation Fragments Modulate Lipopolysaccharide-Stimulated Nuclear Factor-kappa B Nuclear Translocation, Interleukin-1beta and Tumor Necrosis Factor-alpha in Differentiated THP-1 Cells. PLoS One, 11 (4) e0153005, e0153005.1-e0153005.18. doi: 10.1371/journal.pone.0153005

Dynorphin 1-17 and Its N-Terminal Biotransformation Fragments Modulate Lipopolysaccharide-Stimulated Nuclear Factor-kappa B Nuclear Translocation, Interleukin-1beta and Tumor Necrosis Factor-alpha in Differentiated THP-1 Cells

2016

Journal Article

Simultaneous quantitative analysis of nine vitamin D compounds in human blood using LC-MS/MS

Abu Kassim, Nur Sofiah, Gomes, Fabio P., Shaw, Paul Nicholas and Hewavitharana, Amitha K. (2016). Simultaneous quantitative analysis of nine vitamin D compounds in human blood using LC-MS/MS. Bioanalysis, 8 (5), 397-411. doi: 10.4155/bio.15.260

Simultaneous quantitative analysis of nine vitamin D compounds in human blood using LC-MS/MS

2016

Journal Article

Traditional aboriginal preparation alters the chemical profile of carica papaya leaves and impacts on cytotoxicity towards human squamous cell carcinoma

Nguyen, Thao T., Parat, Marie-Odile, Shaw, Paul N., Hewavitharana, Amitha K. and Hodson, Mark P. (2016). Traditional aboriginal preparation alters the chemical profile of carica papaya leaves and impacts on cytotoxicity towards human squamous cell carcinoma. PLoS ONE, 11 (2) e0147956, e0147956. doi: 10.1371/journal.pone.0147956

Traditional aboriginal preparation alters the chemical profile of carica papaya leaves and impacts on cytotoxicity towards human squamous cell carcinoma

2016

Journal Article

Effect of pasteurisation on the concentrations of vitamin D compounds in donor breastmilk

Gomes, Fabio P., Shaw, P. Nicholas, Whitfield, Karen, Koorts, Pieter, McConachy, Helen and Hewavitharana, Amitha K. (2016). Effect of pasteurisation on the concentrations of vitamin D compounds in donor breastmilk. International Journal of Food Sciences and Nutrition, 67 (1), 16-19. doi: 10.3109/09637486.2015.1126566

Effect of pasteurisation on the concentrations of vitamin D compounds in donor breastmilk

2016

Journal Article

Determination of four sulfated vitamin D compounds in human biological fluids by liquid chromatography-tandem mass spectrometry

Gomes, Fabio P., Shaw, P. Nicholas and Hewavitharana, Amitha K. (2016). Determination of four sulfated vitamin D compounds in human biological fluids by liquid chromatography-tandem mass spectrometry. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1009-1010, 80-86. doi: 10.1016/j.jchromb.2015.12.014

Determination of four sulfated vitamin D compounds in human biological fluids by liquid chromatography-tandem mass spectrometry

2016

Journal Article

The simultaneous analysis of eight essential trace elements in human milk by ICP-MS

Mohd-Taufek, Nor, Cartwright, David, Davies, Mark, Hewavitharana, Amitha K., Koorts, Pieter, Shaw, Paul N., Sumner, Ronald, Lee, Eugene and Whitfield, Karen (2016). The simultaneous analysis of eight essential trace elements in human milk by ICP-MS. Food Analytical Methods, 9 (7), 1-8. doi: 10.1007/s12161-015-0396-z

The simultaneous analysis of eight essential trace elements in human milk by ICP-MS

2016

Conference Publication

Establishment of new methods to quantify the Mu-opioid and Tlr-4 receptor activation potential in biological samples to assess the influence of opioids on tumor metastasis

Xie, Nan, Cabot, Peter, Shaw, Paul N., Sturgess, David and Parat, Marie-Odile (2016). Establishment of new methods to quantify the Mu-opioid and Tlr-4 receptor activation potential in biological samples to assess the influence of opioids on tumor metastasis. COSA's 43rd and ANZBCTG's 38th Annual Scientific Meetings. Partners for Progress in Breast Cancer Research and Care, Gold Coast, QLD, Australia, 15–17 November 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Establishment of new methods to quantify the Mu-opioid and Tlr-4 receptor activation potential in biological samples to assess the influence of opioids on tumor metastasis

2016

Journal Article

Chemical characterization and in vitro cytotoxicity on squamous cell carcinoma cells of Carica papaya leaf extracts

Nguyen, Thao T., Parat, Marie-Odile, Hodson, Mark P., Pan, Jenny, Shaw, Paul N. and Hewavitharana, Amitha K. (2016). Chemical characterization and in vitro cytotoxicity on squamous cell carcinoma cells of Carica papaya leaf extracts. Toxins, 8 (1), 7.1-7.11. doi: 10.3390/toxins8010007

Chemical characterization and in vitro cytotoxicity on squamous cell carcinoma cells of Carica papaya leaf extracts

2016

Conference Publication

Medium polarity fraction of papaya leaf juice has selective antiproliferative effects on prostate cancer cells

Pandey, Saurabh, Walpole, Carina, Cabot, Peter J., Shaw, Paul N., Batra, Jyotsna and Hewavitharana, Amitha K. (2016). Medium polarity fraction of papaya leaf juice has selective antiproliferative effects on prostate cancer cells. 17th Asia-Pacific Prostate Cancer Conference, Melbourne, Australia, Aug 31-Sep 03, 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/bju.13567

Medium polarity fraction of papaya leaf juice has selective antiproliferative effects on prostate cancer cells

2015

Journal Article

Breastmilk-saliva interactions boost innate immunity by regulating the oral microbiome in early infancy

Al-Shehri, Saad S., Knox, Christine L., Liley, Helen G., Cowley, David M., Wright, John R., Henman, Michael G., Hewavitharana, Amitha K., Charles, Bruce G., Shaw, Paul N., Sweeney, Emma L. and Duley, John A. (2015). Breastmilk-saliva interactions boost innate immunity by regulating the oral microbiome in early infancy. PLoS One, 10 (9) e0135047, e0135047.1-e0135047.19. doi: 10.1371/journal.pone.0135047

Breastmilk-saliva interactions boost innate immunity by regulating the oral microbiome in early infancy

Past funding

  • 2020 - 2024
    Next-generation feeding for premature babies: 'Bioactive' breastmilk pasteurised by nanosecond pulsed electric field
    NHMRC IDEAS Grants
    Open grant
  • 2020 - 2022
    Next-generation feeding for premature babies: 'bioactive' breastmilk pasteurised by nanosecond pulsed electric field
    The Children's Hospital Foundation
    Open grant
  • 2014 - 2015
    Perioperative opioids and tumour growth and metastasis
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2013 - 2020
    The Diamantina Individualised Oncology Care Centre (DIOCC)
    Australian Cancer Research Foundation
    Open grant
  • 2013 - 2017
    A mechanism for regulation of oral and gut microflora by interaction of salivary metabolites with breast milk
    NHMRC Project Grant
    Open grant
  • 2011
    Establishment of a robotic liquid handling platofrm for the use of 384 and 1536 well plates
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Analytical instrumentation enabling rapid compound separation and chemical structure analysis via mass fingerprinting
    UQ Major Equipment and Infrastructure
    Open grant
  • 2008 - 2011
    Nutritional properties of mango fruits: linking plant genomics to cellular bioactivities
    ARC Linkage Projects
    Open grant
  • 2008 - 2011
    Diversity of Salinispora actinobacteria producing pharmaceutically relevant natural products from Australian marine sponges
    ARC Linkage Projects
    Open grant
  • 2006
    A high resolution, high-throughput chromatographic system for separation and characterisation of complex samples
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2005 - 2008
    Identification of nutritional bioactives in tropical fruit
    ARC Linkage Projects
    Open grant
  • 2005
    Nutrient Metabolomics: In vitro assay approaches to identifying nutritional biomolecules in tropical fruit
    University of Queensland Research Development Grants Scheme
    Open grant

Availability

Professor Nick Shaw is:
Available for supervision

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Available projects

  • The Identification and Quantitation of Opioid Peptides using LC/MS/MS and their Role in Inflammatory Disease

  • Bioanalysis, Bioavailability and Disposition of Phytochemicals from Tropical Fruits

Supervision history

Current supervision

Completed supervision

Enquiries

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