Professor Nick Shaw
Professor

Nick Shaw

Email: 
Phone: 
+61 7 334 65305

Background

Nick Shaw was appointed to the School as Professor in January 2004 and undertook the role of Head of School of Pharmacy at UQ from 1st July 2004 until 31st December 2014. Nick is a pharmacist, graduating PhD from the University of Manchester in 1985 and was a member of the academic staff of the University of Nottingham from 1985-2003. He was appointed a Fellow of the Royal Society of Chemistry in 1994 and a Fellow of the Royal Pharmaceutical Society in 2010. He previously founded and chaired the Council of Pharmacy Schools (Australia and New Zealand); he is the chair of the APC Accreditation Committee and was the chair of the Australian Pharmacy Liaison Forum in 2011. He has taught across a range of subjects to the second and third years of the BPharm (Hons) course at UQ. Nick has supervised and co-supervised over 45 PhD and research Masters students.

In 2013 Nick was awarded the Pharmaceutical Society of Australia’s Bowl of Hygeia for services to the profession.

Availability

Professor Nick Shaw is:
Available for supervision

Fields of research

Analytical chemistry Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Science, The University of Manchester
  • Doctor of Philosophy, The University of Manchester
  • Fellow, Royal Pharmaceutical Society of Great Britain, Royal Pharmaceutical Society of Great Britain
  • Fellow, Royal Society of Chemistry, Royal Society of Chemistry

Research interests

  • Application of a range of analytical methodologies to solve clinical and health-related problems

  • Metabolite profiling methodology applied to nutrient profiles of tropical and other plants and secondary metabolite identification and quantitation from bacteria

  • Drug metabolism, biopharmaceutics, drug delivery and pharmacokinetic studies

Search Professor Nick Shaw’s works on UQ eSpace

295 works between 1980 and 2023
All (295) Journal Article (206) Book Chapter (1) Conference Publication (86) Other Outputs (2)

21 - 40 of 295 works

2020

Journal Article

A novel, quorum sensor-infused liposomal drug delivery system suppresses Candida albicans biofilms

Bandara, H. M.H.N., Hewavitharana, A. K., Shaw, P. N., Smyth, H. D.C. and Samaranayake, L. P. (2020). A novel, quorum sensor-infused liposomal drug delivery system suppresses Candida albicans biofilms. International Journal of Pharmaceutics, 578 119096, 119096. doi: 10.1016/j.ijpharm.2020.119096

A novel, quorum sensor-infused liposomal drug delivery system suppresses Candida albicans biofilms

2020

Journal Article

A role for caveola‐forming proteins caveolin‐1 and CAVIN1 in the pro‐invasive response of glioblastoma to osmotic and hydrostatic pressure

Pu, Wenjun, Qiu, Jiawen, Nassar, Zeyad D., Shaw, Paul N., McMahon, Kerrie‐Ann, Ferguson, Charles, Parton, Robert G., Riggins, Gregory J., Harris, Jonathan M. and Parat, Marie‐Odile (2020). A role for caveola‐forming proteins caveolin‐1 and CAVIN1 in the pro‐invasive response of glioblastoma to osmotic and hydrostatic pressure. Journal of Cellular and Molecular Medicine, 24 (6) jcmm.15076, 3724-3738. doi: 10.1111/jcmm.15076

A role for caveola‐forming proteins caveolin‐1 and CAVIN1 in the pro‐invasive response of glioblastoma to osmotic and hydrostatic pressure

2019

Journal Article

Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice

Khaw, Kooi-Yeong, Parat, Marie-Odile, Shaw, Paul Nicholas, Nguyen, Thao T. T., Pandey, Saurabh, Thurecht, Kristofer J. and Falconer, James Robert (2019). Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice. Scientific Reports, 9 (1) 1716, 1716. doi: 10.1038/s41598-018-37171-9

Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice

2019

Conference Publication

The role of cultural background in the engagement and learning of academically successful, late-stage CALD (culturally and linguistically diverse) and non-CALD pharmacy students at a research-intensive Australian university

Bond, Jacqueline A., Manathunga, Catherine E., Shaw, Paul N. and Steel, Caroline H. (2019). The role of cultural background in the engagement and learning of academically successful, late-stage CALD (culturally and linguistically diverse) and non-CALD pharmacy students at a research-intensive Australian university. 2018 Southern Pharmacy Administration Conference (SPAC), Auburn, United States, 7-9 June 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.sapharm.2019.03.139

The role of cultural background in the engagement and learning of academically successful, late-stage CALD (culturally and linguistically diverse) and non-CALD pharmacy students at a research-intensive Australian university

2018

Journal Article

Bio-Guided Fractionation of Papaya Leaf Juice for Delineating the Components Responsible for the Selective Anti-proliferative Effects on Prostate Cancer Cells

Pandey, Saurabh, Walpole, Carina, Shaw, Paul N., Cabot, Peter J., Hewavitharana, Amitha K. and Batra, Jyotsna (2018). Bio-Guided Fractionation of Papaya Leaf Juice for Delineating the Components Responsible for the Selective Anti-proliferative Effects on Prostate Cancer Cells. Frontiers in Pharmacology, 9 (NOV) 1319, 1319. doi: 10.3389/fphar.2018.01319

Bio-Guided Fractionation of Papaya Leaf Juice for Delineating the Components Responsible for the Selective Anti-proliferative Effects on Prostate Cancer Cells

2018

Journal Article

The effect of breastmilk and saliva combinations on the in vitro growth of oral pathogenic and commensal microorganisms

Sweeney, E. L., Al-Shehri, S. S., Cowley, D. M., Liley, H. G., Bansal, N., Charles, B. G., Shaw, P. N., Duley, J. A. and Knox, C. L. (2018). The effect of breastmilk and saliva combinations on the in vitro growth of oral pathogenic and commensal microorganisms. Scientific Reports, 8 (1) 15112, 15112. doi: 10.1038/s41598-018-33519-3

The effect of breastmilk and saliva combinations on the in vitro growth of oral pathogenic and commensal microorganisms

2018

Journal Article

Standard addition with internal standardisation as an alternative to using stable isotope labelled internal standards to correct for matrix effects-Comparison and validation using liquid chromatography-​tandem mass spectrometric assay of vitamin D

Hewavitharana, Amitha K., Abu Kassim, Nur Sofiah and Shaw, Paul Nicholas (2018). Standard addition with internal standardisation as an alternative to using stable isotope labelled internal standards to correct for matrix effects-Comparison and validation using liquid chromatography-​tandem mass spectrometric assay of vitamin D. Journal of Chromatography A, 1553, 101-107. doi: 10.1016/j.chroma.2018.04.026

Standard addition with internal standardisation as an alternative to using stable isotope labelled internal standards to correct for matrix effects-Comparison and validation using liquid chromatography-​tandem mass spectrometric assay of vitamin D

2018

Journal Article

Effect of perioperative opioids on cancer-relevant circulating parameters: mu opioid receptor and TLR4 activation potential, and proteolytic profile

Xie, Nan, Matigian, Nicholas, Vithanage, Tharindu D., Gregory, Kye, Nassar, Zeyad D., Cabot, Peter J., Shaw, Paul Nicholas, Kirkpatrick, Carl Mj, Lê Cao, Kim-Anh, Sturgess, David and Parat, Marie-Odile (2018). Effect of perioperative opioids on cancer-relevant circulating parameters: mu opioid receptor and TLR4 activation potential, and proteolytic profile. Clinical Cancer Research, 24 (10), 2319-2327. doi: 10.1158/1078-0432.CCR-18-0172

Effect of perioperative opioids on cancer-relevant circulating parameters: mu opioid receptor and TLR4 activation potential, and proteolytic profile

2018

Journal Article

A Simple and Sensitive LC-MS/MS Method for the Simultaneous Determination of Cyclophosphamide and Dexorubicin Concentrations in Human Plasma

He, Wenxuan, Martin, Jennifer H., Shaw, Paul N., Lu, Xianyong, Walpole, Euan T. and Dimeski, Goce (2018). A Simple and Sensitive LC-MS/MS Method for the Simultaneous Determination of Cyclophosphamide and Dexorubicin Concentrations in Human Plasma. Current Pharmaceutical Analysis, 14 (1), 53-59. doi: 10.2174/1573412913666170321111815

A Simple and Sensitive LC-MS/MS Method for the Simultaneous Determination of Cyclophosphamide and Dexorubicin Concentrations in Human Plasma

2017

Journal Article

Simultaneous determination of 12 vitamin D compounds in human serum using online sample preparation and liquid chromatography-tandem mass spectrometry

Abu Kassim, Nur Sofiah, Shaw, Paul Nicholas and Hewavitharana, Amitha K. (2017). Simultaneous determination of 12 vitamin D compounds in human serum using online sample preparation and liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 1533, 57-65. doi: 10.1016/j.chroma.2017.12.012

Simultaneous determination of 12 vitamin D compounds in human serum using online sample preparation and liquid chromatography-tandem mass spectrometry

2017

Journal Article

Evidence for a Saponin Biosynthesis Pathway in the Body Wall of the Commercially Significant Sea Cucumber Holothuria scabra

Mitu, Shahida Akter, Bose, Utpal, Suwansa-Ard, Saowaros, Turner, Luke H., Zhao, Min, Elizur, Abigail, Ogbourne, Steven M., Shaw, Paul Nicholas and Cummins, Scott F. (2017). Evidence for a Saponin Biosynthesis Pathway in the Body Wall of the Commercially Significant Sea Cucumber Holothuria scabra. Marine drugs, 15 (11) 349, 1-14. doi: 10.3390/md15110349

Evidence for a Saponin Biosynthesis Pathway in the Body Wall of the Commercially Significant Sea Cucumber Holothuria scabra

2017

Journal Article

Morphine alters the circulating proteolytic profile in mice: functional consequences on cellular migration and invasion

Xie, Nan, Khabbazi, Samira, Nassar, Zeyad D, Gregory, Kye, Vithanage, Tharindu, Anand-Apte, Bela, Cabot, Peter J, Sturgess, David, Shaw, Paul N and Parat, Marie-Odile (2017). Morphine alters the circulating proteolytic profile in mice: functional consequences on cellular migration and invasion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31 (12), 5208-5216. doi: 10.1096/fj.201700546R

Morphine alters the circulating proteolytic profile in mice: functional consequences on cellular migration and invasion

2017

Journal Article

Solvent supercritical fluid technologies to extract bioactive compounds from natural sources: a review

Khaw, Kooi-Yeong, Parat, Marie-Odile, Shaw, Paul Nicholas and Falconer, James Robert (2017). Solvent supercritical fluid technologies to extract bioactive compounds from natural sources: a review. Molecules, 22 (7) 1186, 1186. doi: 10.3390/molecules22071186

Solvent supercritical fluid technologies to extract bioactive compounds from natural sources: a review

2017

Journal Article

CYP450s analysis across spiny lobster metamorphosis identifies a long sought missing link in crustacean development

Ventura, Tomer, Bose, Utpal, Fitzgibbon, Quinn P., Smith, Gregory G., Shaw, P. Nicholas, Cummins, Scott F. and Elizur, Abigail (2017). CYP450s analysis across spiny lobster metamorphosis identifies a long sought missing link in crustacean development. Journal of Steroid Biochemistry and Molecular Biology, 171, 262-269. doi: 10.1016/j.jsbmb.2017.04.007

CYP450s analysis across spiny lobster metamorphosis identifies a long sought missing link in crustacean development

2017

Journal Article

Biomolecular changes that occur in the antennal gland of the giant freshwater prawn (Machrobrachium rosenbergii)

Bose, Utpal, Kruangkum, Thanapong, Wang, Tianfang, Zhao, Min, Ventura, Tomer, Mitu, Shahida Akter, Hodson, Mark P., Shaw, Paul N., Sobhon, Prasert and Cummins, Scott F. (2017). Biomolecular changes that occur in the antennal gland of the giant freshwater prawn (Machrobrachium rosenbergii). Plos One, 12 (6) 0177064, e0177064. doi: 10.1371/journal.pone.0177064

Biomolecular changes that occur in the antennal gland of the giant freshwater prawn (Machrobrachium rosenbergii)

2017

Journal Article

Selective anti-proliferative activities of Carica papaya leaf juice extracts against prostate cancer

Pandey, Saurabh, Walpole, Carina, Cabot, Peter J., Shaw, Paul N., Batra, Jyotsna and Hewavitharana, Amitha K. (2017). Selective anti-proliferative activities of Carica papaya leaf juice extracts against prostate cancer. Biomedicine & Pharmacotherapy, 89, 515-523. doi: 10.1016/j.biopha.2017.02.050

Selective anti-proliferative activities of Carica papaya leaf juice extracts against prostate cancer

2017

Journal Article

Inhibitory effects of dynorphin 3-14 on the lipopolysaccharide-induced toll-like receptor 4 signalling pathway

Rahiman, Siti Sarah Fazalul, Morgan, Michael, Gray, Paul, Shaw, Paul Nicholas and Cabot, Peter John (2017). Inhibitory effects of dynorphin 3-14 on the lipopolysaccharide-induced toll-like receptor 4 signalling pathway. Peptides, 90, 48-54. doi: 10.1016/j.peptides.2017.02.004

Inhibitory effects of dynorphin 3-14 on the lipopolysaccharide-induced toll-like receptor 4 signalling pathway

2017

Journal Article

Activation of μ-opioid receptor and Toll-like receptor 4 by plasma from morphine-treated mice

Xie, Nan, Gomes, Fabio P., Deora, Vandana, Gregory, Kye, Vithanage, Tharindu, Nassar, Zeyad D., Cabot, Peter J., Sturgess, David, Shaw, Paul N. and Parat, Marie-Odile (2017). Activation of μ-opioid receptor and Toll-like receptor 4 by plasma from morphine-treated mice. Brain, Behavior, and Immunity, 61, 244-258. doi: 10.1016/j.bbi.2016.12.002

Activation of μ-opioid receptor and Toll-like receptor 4 by plasma from morphine-treated mice

2017

Journal Article

The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation

Morgan, M., Heffernan, A., Benhabib, F., Wagner, S., Hewavitharana, A. K., Shaw, P. N. and Cabot, P. J. (2017). The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation. Peptides, 89, 9-16. doi: 10.1016/j.peptides.2016.12.019

The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation

2017

Journal Article

Production of N-acyl homoserine lactones by the sponge-associated marine actinobacteria Salinispora arenicola and Salinispora pacifica

Bose, Utpal, Ortori, Catharine A., Sarmad, Sarir , Barrett, David A., Hewavitharana, Amitha K. , Hodson, Mark P., Fuerst, John A. and Shaw, P. Nicholas (2017). Production of N-acyl homoserine lactones by the sponge-associated marine actinobacteria Salinispora arenicola and Salinispora pacifica. FEMS Microbiology Letters, 364 (2) fnx002. doi: 10.1093/femsle/fnx002

Production of N-acyl homoserine lactones by the sponge-associated marine actinobacteria Salinispora arenicola and Salinispora pacifica

Past funding

  • 2020 - 2024
    Next-generation feeding for premature babies: 'Bioactive' breastmilk pasteurised by nanosecond pulsed electric field
    NHMRC IDEAS Grants
    Open grant
  • 2020 - 2022
    Next-generation feeding for premature babies: 'bioactive' breastmilk pasteurised by nanosecond pulsed electric field
    The Children's Hospital Foundation
    Open grant
  • 2014 - 2015
    Perioperative opioids and tumour growth and metastasis
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2013 - 2020
    The Diamantina Individualised Oncology Care Centre (DIOCC)
    Australian Cancer Research Foundation
    Open grant
  • 2013 - 2017
    A mechanism for regulation of oral and gut microflora by interaction of salivary metabolites with breast milk
    NHMRC Project Grant
    Open grant
  • 2011
    Establishment of a robotic liquid handling platofrm for the use of 384 and 1536 well plates
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Analytical instrumentation enabling rapid compound separation and chemical structure analysis via mass fingerprinting
    UQ Major Equipment and Infrastructure
    Open grant
  • 2008 - 2011
    Nutritional properties of mango fruits: linking plant genomics to cellular bioactivities
    ARC Linkage Projects
    Open grant
  • 2008 - 2011
    Diversity of Salinispora actinobacteria producing pharmaceutically relevant natural products from Australian marine sponges
    ARC Linkage Projects
    Open grant
  • 2006
    A high resolution, high-throughput chromatographic system for separation and characterisation of complex samples
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2005 - 2008
    Identification of nutritional bioactives in tropical fruit
    ARC Linkage Projects
    Open grant
  • 2005
    Nutrient Metabolomics: In vitro assay approaches to identifying nutritional biomolecules in tropical fruit
    University of Queensland Research Development Grants Scheme
    Open grant

Availability

Professor Nick Shaw is:
Available for supervision

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Available projects

  • The Identification and Quantitation of Opioid Peptides using LC/MS/MS and their Role in Inflammatory Disease

  • Bioanalysis, Bioavailability and Disposition of Phytochemicals from Tropical Fruits

Supervision history

Current supervision

Completed supervision

Enquiries

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