Professor Nick Shaw
Professor

Nick Shaw

Email: 
Phone: 
+61 7 334 65305

Background

Nick Shaw was appointed to the School as Professor in January 2004 and undertook the role of Head of School of Pharmacy at UQ from 1st July 2004 until 31st December 2014. Nick is a pharmacist, graduating PhD from the University of Manchester in 1985 and was a member of the academic staff of the University of Nottingham from 1985-2003. He was appointed a Fellow of the Royal Society of Chemistry in 1994 and a Fellow of the Royal Pharmaceutical Society in 2010. He previously founded and chaired the Council of Pharmacy Schools (Australia and New Zealand); he is the chair of the APC Accreditation Committee and was the chair of the Australian Pharmacy Liaison Forum in 2011. He has taught across a range of subjects to the second and third years of the BPharm (Hons) course at UQ. Nick has supervised and co-supervised over 45 PhD and research Masters students.

In 2013 Nick was awarded the Pharmaceutical Society of Australia’s Bowl of Hygeia for services to the profession.

Availability

Professor Nick Shaw is:
Available for supervision

Fields of research

Analytical chemistry Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Science, The University of Manchester
  • Doctor of Philosophy, The University of Manchester
  • Fellow, Royal Pharmaceutical Society of Great Britain, Royal Pharmaceutical Society of Great Britain
  • Fellow, Royal Society of Chemistry, Royal Society of Chemistry

Research interests

  • Application of a range of analytical methodologies to solve clinical and health-related problems

  • Metabolite profiling methodology applied to nutrient profiles of tropical and other plants and secondary metabolite identification and quantitation from bacteria

  • Drug metabolism, biopharmaceutics, drug delivery and pharmacokinetic studies

Search Professor Nick Shaw’s works on UQ eSpace

295 works between 1980 and 2023
All (295) Journal Article (206) Book Chapter (1) Conference Publication (86) Other Outputs (2)

161 - 180 of 295 works

2006

Journal Article

Saponins from Quillaja saponaria Molina: Isolation, Characterization and Ability to Form Immuno Stimulatory Complexes (ISCOMs)

Pham, H. L., Ross, B. P., McGeary, R. P., Shaw, P. N., Hewavitharana, A. K. and Davies, N. M. (2006). Saponins from Quillaja saponaria Molina: Isolation, Characterization and Ability to Form Immuno Stimulatory Complexes (ISCOMs). Current Drug Delivery, 3 (4), 389-397. doi: 10.2174/156720106778559092

Saponins from Quillaja saponaria Molina: Isolation, Characterization and Ability to Form Immuno Stimulatory Complexes (ISCOMs)

2006

Journal Article

Disruption of NaS1 sulfate transport function in mice leads to enhanced acetaminophen-induced hepatotoxicity

Lee, S., Dawson, P. A., Hewavitharana, A. K., Shaw, P. N. and Markovich, D. (2006). Disruption of NaS1 sulfate transport function in mice leads to enhanced acetaminophen-induced hepatotoxicity. Hepatology, 43 (6), 1241-1247. doi: 10.1002/hep.21207

Disruption of NaS1 sulfate transport function in mice leads to enhanced acetaminophen-induced hepatotoxicity

2006

Journal Article

Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction

Kim, T. K., Hewavitharana, A. K., Shaw, P. N. and Fuerst, J. A. (2006). Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction. Applied And Environmental Microbiology, 72 (3), 2118-2125. doi: 10.1128/AEM.72.3.2118-2125.2006

Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction

2006

Conference Publication

Increased acetaminophen hepatotoxicity in the NaS1 and Sat1 sulfate transporter null mice

Lee, S, Dawson, P A, Hewavitharana, A, Shaw, P N and Markovich, D (2006). Increased acetaminophen hepatotoxicity in the NaS1 and Sat1 sulfate transporter null mice. ComBio2006, Brisbane / Brisbane Convention Centre, 24-28 September 2006. Brisbane: Australian Physiological Society.

Increased acetaminophen hepatotoxicity in the NaS1 and Sat1 sulfate transporter null mice

2006

Conference Publication

Identification and quantitation of intact beta-endorphin by LC-MS-MS

Cabot, P. J., Hewavitharana, A., Pham, U. and Shaw, P. N. (2006). Identification and quantitation of intact beta-endorphin by LC-MS-MS. BPC Science: British Pharmaceutical Conference, Manchester UK / Manchester International Convention Centre, 4-6 September 2006. West Sussex, U.K.: John Wiley & Sons. doi: 10.1211/002235706778251393

Identification and quantitation of intact beta-endorphin by LC-MS-MS

2006

Journal Article

Preparation of immuno-stimulating complexes (ISCOMs) by ether injection

Pham, H. L., Shaw, P. N. and Davies, N. M. (2006). Preparation of immuno-stimulating complexes (ISCOMs) by ether injection. International Journal of Pharmaceutics, 310 (1-2), 196-202. doi: 10.1016/j.ijpharm.2005.11.011

Preparation of immuno-stimulating complexes (ISCOMs) by ether injection

2006

Conference Publication

Nutritional bioactives in tropical fruit

Wilkinson, A, Hewavitharana, A, Flanagan, B M, Dietzgen, R G, Monteith, G R, Shaw, P N, Roberts-Thomson, S J and Gidley, M (2006). Nutritional bioactives in tropical fruit. The 3rd Australian Health & Medical Research Congress, Melbourne Convention Centre, Melbourne, Australia, 26 November-1 December, 2006. Melbourne, Vic, Australia: National Health and Medical Research Council.

Nutritional bioactives in tropical fruit

2006

Conference Publication

Norathyriol, the active metabolite of mangiferin, modulates PPAR activity and is a potential nutritional bioactive

Wilkinson, A. S., Lin, C. N., Dietzgen, R. G., Monteith, G. R., Shaw, P. N., Roberts-Thomson, S. J. and Gidley, M. (2006). Norathyriol, the active metabolite of mangiferin, modulates PPAR activity and is a potential nutritional bioactive. Annual Conference of the Australasian Pharmaceutical Science Association, Adelaide Hilton, Adelaide, South Australia, 3-5 December, 2006. Malvern,Vic, Australia: Australasian Pharmaceutical Science Association.

Norathyriol, the active metabolite of mangiferin, modulates PPAR activity and is a potential nutritional bioactive

2006

Conference Publication

Profiling acetaminophen metabolites in mouse urine by LC-MS-MS

Shaw, P N, Hewavitharana, A, Lee, S, Dawson, P A and Markovich, D (2006). Profiling acetaminophen metabolites in mouse urine by LC-MS-MS. British Pharmaceutical Conference, Manchester UK / Mancester International Convention Centre, 4-6 September 2006. Belfast, Northern Ireland: Pharmaceutical Press.

Profiling acetaminophen metabolites in mouse urine by LC-MS-MS

2006

Journal Article

Shortcomings of protein removal prior to high performance liquid chromatographic analysis - A case study using method development for BAY 11-7082

Hewavitharana, A. K., Hyde, C., Thomas, R. and Shaw, P. N. (2006). Shortcomings of protein removal prior to high performance liquid chromatographic analysis - A case study using method development for BAY 11-7082. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 834 (1-2), 93-97. doi: 10.1016/j.jchromb.2006.02.037

Shortcomings of protein removal prior to high performance liquid chromatographic analysis - A case study using method development for BAY 11-7082

2006

Conference Publication

Profiling acetaminophen metabolites in mouse urine by LC-MS-MS

Shaw, P. N., Hewavitharana, A. K., Lee, S., Dawson, P. and Markovich, D. (2006). Profiling acetaminophen metabolites in mouse urine by LC-MS-MS. The British Pharmaceutical Conference, Manchester, England, 4-6 September 2006. West Sussex, England, U.K.: John Wiley & Sons Ltd.. doi: 10.1211/002235706778251375

Profiling acetaminophen metabolites in mouse urine by LC-MS-MS

2006

Conference Publication

Assessment of the presence of Rifamycin antibiotics in marine sponge bacterium Salinispora using LC-MS-MS

Hewavitharana, A, Shaw, P N, Kim, T. K. and Fuerst, J A (2006). Assessment of the presence of Rifamycin antibiotics in marine sponge bacterium Salinispora using LC-MS-MS. INTERACT 2006: Air, Water and Earth: INTERACT in Perth, Perth, Australia, 24-28 September 2006. Canning Bridge, Australia: Promaco Conventions.

Assessment of the presence of Rifamycin antibiotics in marine sponge bacterium Salinispora using LC-MS-MS

2006

Journal Article

Quantitative measurement of sulforaphane, iberin and their mercapturic acid pathway metabolites in human plasma and urine using liquid chromatography-tandem electrospray ionisation mass spectrometry

Al Janobi, A. A., Mithen, R. F., Gasper, A. V., Shaw, P. N., Middleton, R. J., Ortori, C. A. and Barrett, D. A. (2006). Quantitative measurement of sulforaphane, iberin and their mercapturic acid pathway metabolites in human plasma and urine using liquid chromatography-tandem electrospray ionisation mass spectrometry. Journal of Chromatography B - analytical Technologies In The Biomedical And Life Sciences, 844 (2), 223-234. doi: 10.1016/j.jchromb.2006.07.007

Quantitative measurement of sulforaphane, iberin and their mercapturic acid pathway metabolites in human plasma and urine using liquid chromatography-tandem electrospray ionisation mass spectrometry

2005

Journal Article

A generic approach to the impurity profiling of drugs using standardised and independent capillary zone electrophoresis methods coupled to electrospray ionisation mass spectrometry

Vassort, Aurélie, Barrett, David A., Shaw, P. Nicholas, Ferguson, Paul D. and Szucs, Roman (2005). A generic approach to the impurity profiling of drugs using standardised and independent capillary zone electrophoresis methods coupled to electrospray ionisation mass spectrometry. Electrophoresis, 26 (9), 1712-1723. doi: 10.1002/elps.200410261

A generic approach to the impurity profiling of drugs using standardised and independent capillary zone electrophoresis methods coupled to electrospray ionisation mass spectrometry

2005

Journal Article

Amino acid analysis by micellar electrokinetic chromatography with laser-induced fluorescence detection: Application to nanolitre-volume biological samples from Arabidopsis thaliana and Myzus persicae

Zhu, Xunlin, Shaw, P. Nicholas, Pritchard, Jeremy, Newbury, John, Hunt, Emma J. and Barrett, David A. (2005). Amino acid analysis by micellar electrokinetic chromatography with laser-induced fluorescence detection: Application to nanolitre-volume biological samples from Arabidopsis thaliana and Myzus persicae. Electrophoresis, 26 (4-5), 911-919. doi: 10.1002/elps.200410259

Amino acid analysis by micellar electrokinetic chromatography with laser-induced fluorescence detection: Application to nanolitre-volume biological samples from Arabidopsis thaliana and Myzus persicae

2005

Conference Publication

Development and application of a liposome delivery method to enhance the bioavailability of antioxidants and evaluate cytotoxicity in colon and breast cancer in vitro models

Sutherland, A., Hewavitharana, A., Flanagan, B. M., Monteith, G. R., Shaw, N., Roberts-Thomson, S. J. and Gidley, M. (2005). Development and application of a liposome delivery method to enhance the bioavailability of antioxidants and evaluate cytotoxicity in colon and breast cancer in vitro models. 29th Annual Scientific Meeting of Nutrition Society of Australia, Melbourne, Vic, Australia, 30 November-3 December, 2005. Clayton, Vic., Australia: Blackwell Science Asia.

Development and application of a liposome delivery method to enhance the bioavailability of antioxidants and evaluate cytotoxicity in colon and breast cancer in vitro models

2005

Journal Article

Enhancing the ratio of molecular ions to non-covalent compounds in the electrospray interface of LC-MS in quantitative analysis

Hewavitharana, AK and Shaw, PN (2005). Enhancing the ratio of molecular ions to non-covalent compounds in the electrospray interface of LC-MS in quantitative analysis. Analytical And Bioanalytical Chemistry, 382 (4), 1055-1059. doi: 10.1007/s00216-005-3236-y

Enhancing the ratio of molecular ions to non-covalent compounds in the electrospray interface of LC-MS in quantitative analysis

2005

Conference Publication

Manipulation of the population of non-covalently bound species formed in the electrospray interface of LC-MS

Hewavitharana, A. and Shaw, N. (2005). Manipulation of the population of non-covalently bound species formed in the electrospray interface of LC-MS. Australian & New Zealand Society for Mass Spectrometry - 20th Conference, Adelaide, Australia, 30 Jan. - 3 Feb. 2005. Australia:

Manipulation of the population of non-covalently bound species formed in the electrospray interface of LC-MS

2005

Journal Article

Protein interactions with model chromatographic stationary phases constructed using self-assembled monolayers

Barrett, DA, Power, GM, Hussain, MA, Pitfield, ID, Shaw, PN and Davies, MC (2005). Protein interactions with model chromatographic stationary phases constructed using self-assembled monolayers. Journal of Separation Science, 28 (5), 483-491. doi: 10.1002/jssc.200301667

Protein interactions with model chromatographic stationary phases constructed using self-assembled monolayers

2005

Conference Publication

Effect of drug-protein interactions on drug assay

Hewavitharana, A., Shaw, N., Hyde, C. and Thomas, R. (2005). Effect of drug-protein interactions on drug assay. Joint Meeting of ASCEPT and APSA, Melbourne, Australia, 4-7 December 2005. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Effect of drug-protein interactions on drug assay

Past funding

  • 2020 - 2024
    Next-generation feeding for premature babies: 'Bioactive' breastmilk pasteurised by nanosecond pulsed electric field
    NHMRC IDEAS Grants
    Open grant
  • 2020 - 2022
    Next-generation feeding for premature babies: 'bioactive' breastmilk pasteurised by nanosecond pulsed electric field
    The Children's Hospital Foundation
    Open grant
  • 2014 - 2015
    Perioperative opioids and tumour growth and metastasis
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2013 - 2020
    The Diamantina Individualised Oncology Care Centre (DIOCC)
    Australian Cancer Research Foundation
    Open grant
  • 2013 - 2017
    A mechanism for regulation of oral and gut microflora by interaction of salivary metabolites with breast milk
    NHMRC Project Grant
    Open grant
  • 2011
    Establishment of a robotic liquid handling platofrm for the use of 384 and 1536 well plates
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Analytical instrumentation enabling rapid compound separation and chemical structure analysis via mass fingerprinting
    UQ Major Equipment and Infrastructure
    Open grant
  • 2008 - 2011
    Nutritional properties of mango fruits: linking plant genomics to cellular bioactivities
    ARC Linkage Projects
    Open grant
  • 2008 - 2011
    Diversity of Salinispora actinobacteria producing pharmaceutically relevant natural products from Australian marine sponges
    ARC Linkage Projects
    Open grant
  • 2006
    A high resolution, high-throughput chromatographic system for separation and characterisation of complex samples
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2005 - 2008
    Identification of nutritional bioactives in tropical fruit
    ARC Linkage Projects
    Open grant
  • 2005
    Nutrient Metabolomics: In vitro assay approaches to identifying nutritional biomolecules in tropical fruit
    University of Queensland Research Development Grants Scheme
    Open grant

Availability

Professor Nick Shaw is:
Available for supervision

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Available projects

  • The Identification and Quantitation of Opioid Peptides using LC/MS/MS and their Role in Inflammatory Disease

  • Bioanalysis, Bioavailability and Disposition of Phytochemicals from Tropical Fruits

Supervision history

Current supervision

Completed supervision

Enquiries

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