Professor Nick Shaw
Professor

Nick Shaw

Email: 
Phone: 
+61 7 334 65305

Background

Nick Shaw was appointed to the School as Professor in January 2004 and undertook the role of Head of School of Pharmacy at UQ from 1st July 2004 until 31st December 2014. Nick is a pharmacist, graduating PhD from the University of Manchester in 1985 and was a member of the academic staff of the University of Nottingham from 1985-2003. He was appointed a Fellow of the Royal Society of Chemistry in 1994 and a Fellow of the Royal Pharmaceutical Society in 2010. He previously founded and chaired the Council of Pharmacy Schools (Australia and New Zealand); he is the chair of the APC Accreditation Committee and was the chair of the Australian Pharmacy Liaison Forum in 2011. He has taught across a range of subjects to the second and third years of the BPharm (Hons) course at UQ. Nick has supervised and co-supervised over 45 PhD and research Masters students.

In 2013 Nick was awarded the Pharmaceutical Society of Australia’s Bowl of Hygeia for services to the profession.

Availability

Professor Nick Shaw is:
Available for supervision

Fields of research

Analytical chemistry Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Science, The University of Manchester
  • Doctor of Philosophy, The University of Manchester
  • Fellow, Royal Pharmaceutical Society of Great Britain, Royal Pharmaceutical Society of Great Britain
  • Fellow, Royal Society of Chemistry, Royal Society of Chemistry

Research interests

  • Application of a range of analytical methodologies to solve clinical and health-related problems

  • Metabolite profiling methodology applied to nutrient profiles of tropical and other plants and secondary metabolite identification and quantitation from bacteria

  • Drug metabolism, biopharmaceutics, drug delivery and pharmacokinetic studies

Search Professor Nick Shaw’s works on UQ eSpace

295 works between 1980 and 2023
All (295) Journal Article (206) Book Chapter (1) Conference Publication (86) Other Outputs (2)

181 - 200 of 295 works

2005

Journal Article

Quantitative determination of alkylated quaternary amines and their n-hydroxylated metabolites in an enzyme incubation matrix by liquid chromatography electrospray ionization mass spectrometry

Holmes, VE, Shaw, PN, Ortori, CA and Barrett, DA (2005). Quantitative determination of alkylated quaternary amines and their n-hydroxylated metabolites in an enzyme incubation matrix by liquid chromatography electrospray ionization mass spectrometry. Biomedical Chromatography, 19 (8), 579-585. doi: 10.1002/bmc.483

Quantitative determination of alkylated quaternary amines and their n-hydroxylated metabolites in an enzyme incubation matrix by liquid chromatography electrospray ionization mass spectrometry

2004

Journal Article

Molecular analysis of peroxisome proliferation in the hamster

Choudhury, Agharul I., Sims, Helen M., Horley, Neill J., Roberts, Ruth A., Tomlinson, Simon R., Salter, Andrew M., Bruce, Mary, Shaw, P. Nicholas, Kendall, David, Barrett, David A. and Bell, David R. (2004). Molecular analysis of peroxisome proliferation in the hamster. Toxicology and Applied Pharmacology, 197 (1), 9-18. doi: 10.1016/j.taap.2004.01.019

Molecular analysis of peroxisome proliferation in the hamster

2004

Journal Article

A gas chromatography-mass spectrometry method for the measurement of fatty acid omega and omega(-1) hydroxylation kinetics by CYP4A1 using an artificial membrane system

Holmes, Victoria E., Bruce, Mary, Shaw, P. Nicholas, Bell, David R., Qi, Fan Ming and Barrett, David A. (2004). A gas chromatography-mass spectrometry method for the measurement of fatty acid omega and omega(-1) hydroxylation kinetics by CYP4A1 using an artificial membrane system. Analytical Biochemistry, 325 (2), 354-363. doi: 10.1016/j.ab.2003.10.046

A gas chromatography-mass spectrometry method for the measurement of fatty acid omega and omega(-1) hydroxylation kinetics by CYP4A1 using an artificial membrane system

2004

Journal Article

Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver

Jeffery, B, Choudhury, AI, Horley, N, Bruce, M, Tomlinson, SR, Roberts, RA, Gray, TJB, Barrett, DA, Shaw, PN, Kendall, D and Bell, DR (2004). Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver. Archives of Biochemistry And Biophysics, 429 (2), 231-236. doi: 10.1016/j.abb.2004.06.025

Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver

2004

Conference Publication

Pharmacist prescribing: The UK-NHS approach

Shaw, N. (2004). Pharmacist prescribing: The UK-NHS approach. SHPA Qld Branch Conference, Toowoomba, 16-18 July 2004. Australia: SHPA.

Pharmacist prescribing: The UK-NHS approach

2004

Journal Article

Selectivity of 7-alkoxycoumarins as probe substrates for rat hepatic cytochrome P450 forms is influenced by the substitution pattern on the coumarin nucleus

Fry, JR, Hammond, AH, Jassi, KL, Bass, AE, Bruce, G, Laughton, C, Shaw, PN, Bylov, IE and Kovalenko, SM (2004). Selectivity of 7-alkoxycoumarins as probe substrates for rat hepatic cytochrome P450 forms is influenced by the substitution pattern on the coumarin nucleus. Xenobiotica, 34 (8), 707-722. doi: 10.1080/00498250400003463

Selectivity of 7-alkoxycoumarins as probe substrates for rat hepatic cytochrome P450 forms is influenced by the substitution pattern on the coumarin nucleus

2003

Journal Article

Quantification of clarithromycin, its 14-hydroxy and decladinose metabolites in rat plasma, gastric juice and gastric tissue using high-performance liquid chromatography with electrochemical detection

Wibawa, J. I.D, Shaw, P. N. and Barrett, D. A. (2003). Quantification of clarithromycin, its 14-hydroxy and decladinose metabolites in rat plasma, gastric juice and gastric tissue using high-performance liquid chromatography with electrochemical detection. Journal of Chromatography B, 783 (2), 359-366. doi: 10.1016/S1570-0232(02)00765-1

Quantification of clarithromycin, its 14-hydroxy and decladinose metabolites in rat plasma, gastric juice and gastric tissue using high-performance liquid chromatography with electrochemical detection

2003

Journal Article

Catecholamines derivatized with 4-fluoro-7-nitro-2,1,3-benzoxadiazole: characterization of chemical structure and fluorescence properties

Zhu, Xunlin, Shaw, P. Nicholas and Barrett, David A. (2003). Catecholamines derivatized with 4-fluoro-7-nitro-2,1,3-benzoxadiazole: characterization of chemical structure and fluorescence properties. Analytica Chimica Acta, 478 (2), 259-269. doi: 10.1016/S0003-2670(02)01515-5

Catecholamines derivatized with 4-fluoro-7-nitro-2,1,3-benzoxadiazole: characterization of chemical structure and fluorescence properties

2002

Journal Article

Measurement of amoxicillin in plasma and gastric samples using high-performance liquid chromatography with fluorimetric detection

Wibawa, JJD, Fowkes, D, Shaw, PN and Barrett, DA (2002). Measurement of amoxicillin in plasma and gastric samples using high-performance liquid chromatography with fluorimetric detection. Journal of Chromatography B-analytical Technologies In The Biomedical And Life Sciences, 774 (2), 141-148. doi: 10.1016/S1570-0232(02)00179-4

Measurement of amoxicillin in plasma and gastric samples using high-performance liquid chromatography with fluorimetric detection

2002

Conference Publication

Study of the residues in conserved C-helix region of CYP4A1: Bacterial expression and mutagenesis

Fan, M.Q., Holmes, V., Laughton, C.A., Shaw, P.N., Barrett, D.A. and Bell, D.R. (2002). Study of the residues in conserved C-helix region of CYP4A1: Bacterial expression and mutagenesis. BTS Annual Congress, Canterbury, United Kingdom, 7-10 April 2002. CLARE: ELSEVIER SCI IRELAND LTD.

Study of the residues in conserved C-helix region of CYP4A1: Bacterial expression and mutagenesis

2002

Journal Article

Impact of acid secretion, gastritis, and mucus thickness on gastric transfer of antibiotics in rats

Sherwood, PV, Wibawa, JID, Atherton, JC, Jordan, N, Jenkins, D, Barrett, DA, Shaw, PN and Spiller, RC (2002). Impact of acid secretion, gastritis, and mucus thickness on gastric transfer of antibiotics in rats. Gut, 51 (4), 490-495. doi: 10.1136/gut.51.4.490

Impact of acid secretion, gastritis, and mucus thickness on gastric transfer of antibiotics in rats

2002

Conference Publication

Study of the Residues in Conserved C-helix Region of CYP4A1: Bacterial Expression and Mutagenesis

Fan, Ming Qi, Holmes, Victoria, Laughton, Charles A., Shaw, P. Nicholas, Barrett, David A. and Bell, David R. (2002). Study of the Residues in Conserved C-helix Region of CYP4A1: Bacterial Expression and Mutagenesis. BTS Annual Congress, University of Kent, Canterbury, Kent, 7–10 April, 2002. Ireland: Elsevier Science. doi: 10.1016/S0300-483X(02)00200-7

Study of the Residues in Conserved C-helix Region of CYP4A1: Bacterial Expression and Mutagenesis

2002

Journal Article

Retention behaviour of an homologous series of oligodeoxythymidilic acids using reversed-phase ion-pair chromatography

McKeown, AP, Shaw, PN and Barrett, DA (2002). Retention behaviour of an homologous series of oligodeoxythymidilic acids using reversed-phase ion-pair chromatography. Chromatographia, 55 (5-6), 271-277. doi: 10.1007/BF02491658

Retention behaviour of an homologous series of oligodeoxythymidilic acids using reversed-phase ion-pair chromatography

2002

Conference Publication

Structure-Activity Relationships of CYP4A1

Holmes, Victoria E., Qi, Fan Ming, Laughton, Charlie A., Bell, David R., Shaw, P. Nick and Barrett, David A. (2002). Structure-Activity Relationships of CYP4A1. British Toxicology Society Annual Congress, Ireland, 7th - 10th April, 2002. Ireland: Elsevier Science Ireland. doi: 10.1016/S0300-483X(02)00200-7

Structure-Activity Relationships of CYP4A1

2001

Conference Publication

Gastric secretion of amoxicillin and metronidazole is increased by pronase, a luminal mucolytic

Sherwood, P.V., Wibawa, J.I.D., Jordan, N., Barrett, D.A., Shaw, P.N. and Spiller, R.C. (2001). Gastric secretion of amoxicillin and metronidazole is increased by pronase, a luminal mucolytic. Annual Meeting of the British Society of Gastroenterology, Unknown, 2001. London, United Kingdom: B M J Group.

Gastric secretion of amoxicillin and metronidazole is increased by pronase, a luminal mucolytic

2001

Journal Article

Effects of acid treatment on the trace metal content of chromatographic silica: bulk analysis, surface analysis and chromatographic performance of bonded phases

Barrett, DA, Brown, VA, Watson, RC, Davies, MC, Shaw, PN, Ritchie, HJ and Ross, P (2001). Effects of acid treatment on the trace metal content of chromatographic silica: bulk analysis, surface analysis and chromatographic performance of bonded phases. Journal of Chromatography A, 905 (1-2), 69-83. doi: 10.1016/S0021-9673(00)01000-1

Effects of acid treatment on the trace metal content of chromatographic silica: bulk analysis, surface analysis and chromatographic performance of bonded phases

2001

Journal Article

Evaporative light-scattering detection coupled to microcolumn liquid chromatography for the analysis of underivatized amino acids: Sensitivity, linearity of response and comparisons with UV absorbance detection

Cobb, Z, Shaw, PN, Lloyd, LL, Wrench, N and Barrett, DA (2001). Evaporative light-scattering detection coupled to microcolumn liquid chromatography for the analysis of underivatized amino acids: Sensitivity, linearity of response and comparisons with UV absorbance detection. Journal of Microcolumn Separations, 13 (4), 169-175. doi: 10.1002/mcs.1037

Evaporative light-scattering detection coupled to microcolumn liquid chromatography for the analysis of underivatized amino acids: Sensitivity, linearity of response and comparisons with UV absorbance detection

2001

Journal Article

Systemic levels of glyceryl trinitrate following topical application to the anoderm do not correlate with the measured reduction in anal pressure

Jonas, M., Barrett, D. A., Shaw, P. N. and Scholefield, J. H. (2001). Systemic levels of glyceryl trinitrate following topical application to the anoderm do not correlate with the measured reduction in anal pressure. British Journal of Surgery, 88 (12), 1613-1616. doi: 10.1046/j.0007-1323.2001.01932.x

Systemic levels of glyceryl trinitrate following topical application to the anoderm do not correlate with the measured reduction in anal pressure

2001

Conference Publication

Effect of Helicobacter gastritis on gastric antibiotic secretion in man

Sherwood, P.V., Wibawa, J.I.D., Barrett, D.A., Shaw, P.N., Jenkins, D. and Spiller, R.C. (2001). Effect of Helicobacter gastritis on gastric antibiotic secretion in man. Annual Meeting of the British Society of Gastroenterology, Unknown, 2001. London, United Kingdom: B M J Group.

Effect of Helicobacter gastritis on gastric antibiotic secretion in man

2001

Conference Publication

Gastric secretion of amoxicillin and metronidazole, but not clarithromycin, is increased by pronase, a luminal mucolytic

Sherwood, P. V., Wibawa, J. I., Jordan, N., Barrett, D. A., Shaw, P. N. and Spiller, R. C. (2001). Gastric secretion of amoxicillin and metronidazole, but not clarithromycin, is increased by pronase, a luminal mucolytic. Digestive Disease Week and the 102nd Annual Meeting of the American Gastroenterological Association, Atlanta, GA, United States, 20-23 May 2001. Maryland Heights, MO, United States: W.B. Saunders. doi: 10.1016/S0016-5085(08)80586-0

Gastric secretion of amoxicillin and metronidazole, but not clarithromycin, is increased by pronase, a luminal mucolytic

Past funding

  • 2020 - 2024
    Next-generation feeding for premature babies: 'Bioactive' breastmilk pasteurised by nanosecond pulsed electric field
    NHMRC IDEAS Grants
    Open grant
  • 2020 - 2022
    Next-generation feeding for premature babies: 'bioactive' breastmilk pasteurised by nanosecond pulsed electric field
    The Children's Hospital Foundation
    Open grant
  • 2014 - 2015
    Perioperative opioids and tumour growth and metastasis
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2013 - 2020
    The Diamantina Individualised Oncology Care Centre (DIOCC)
    Australian Cancer Research Foundation
    Open grant
  • 2013 - 2017
    A mechanism for regulation of oral and gut microflora by interaction of salivary metabolites with breast milk
    NHMRC Project Grant
    Open grant
  • 2011
    Establishment of a robotic liquid handling platofrm for the use of 384 and 1536 well plates
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Analytical instrumentation enabling rapid compound separation and chemical structure analysis via mass fingerprinting
    UQ Major Equipment and Infrastructure
    Open grant
  • 2008 - 2011
    Nutritional properties of mango fruits: linking plant genomics to cellular bioactivities
    ARC Linkage Projects
    Open grant
  • 2008 - 2011
    Diversity of Salinispora actinobacteria producing pharmaceutically relevant natural products from Australian marine sponges
    ARC Linkage Projects
    Open grant
  • 2006
    A high resolution, high-throughput chromatographic system for separation and characterisation of complex samples
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2005 - 2008
    Identification of nutritional bioactives in tropical fruit
    ARC Linkage Projects
    Open grant
  • 2005
    Nutrient Metabolomics: In vitro assay approaches to identifying nutritional biomolecules in tropical fruit
    University of Queensland Research Development Grants Scheme
    Open grant

Availability

Professor Nick Shaw is:
Available for supervision

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Available projects

  • The Identification and Quantitation of Opioid Peptides using LC/MS/MS and their Role in Inflammatory Disease

  • Bioanalysis, Bioavailability and Disposition of Phytochemicals from Tropical Fruits

Supervision history

Current supervision

Completed supervision

Enquiries

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