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Associate Professor Adam Irwin
Associate Professor

Adam Irwin

Email: 
Phone: 
+61 7 334 66075

Overview

Background

Dr Adam Irwin is a Principal Research Fellow in Paediatric Infectious Diseases at The University of Queensland and Queensland Children’s Hospital in Brisbane, Australia. His research focuses on the early recognition of invasive infections and sepsis, and the optimal use of antimicrobials in children. He is the medical co-chair of the Queensland Paediatric Sepsis Program which was awarded a Global Sepsis Alliance award in 2020, and Queensland Health Excellence awards in 2022 for Healthcare Delivery and Consumer Engagement, and a member of the Australian Group on Antimicrobial Resistance-Kids Steering Committee. He is a recipient of a National Health and Medical Research Council Emerging Leadership Fellowship to investigate the management of multi-drug resistant gram-negative infections in children.

Adam studied at the University of Birmingham Medical School and completed training in Paediatric Infectious Disease and Immunology in London. He was awarded his PhD by the University of Liverpool Institute of Infection and Global Health in 2016. Prior to relocating to Queensland, he was secretary of the British Paediatric Allergy, Immunity and Infection Group.

Availability

Associate Professor Adam Irwin is:
Available for supervision
Media expert

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, University of Birmingham
  • Doctor of Philosophy, University of Liverpool

Works

Search Professor Adam Irwin’s works on UQ eSpace

88 works between 2001 and 2025

61 - 80 of 88 works

2021

Other Outputs

Microsampling for monitoring gentamicin in neonates

Parker, Suzanne L., Irwin, Adam D., Hosking, Francine, August, Deanne, Schoenmaker, Brittany, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Davies, Mark W (2021). Microsampling for monitoring gentamicin in neonates. doi: 10.1101/2021.03.27.21254449

Microsampling for monitoring gentamicin in neonates

2021

Other Outputs

MicroPIPE: An end-to-end solution for high-quality complete bacterial genome construction

Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: An end-to-end solution for high-quality complete bacterial genome construction. doi: 10.1101/2021.02.02.429319

MicroPIPE: An end-to-end solution for high-quality complete bacterial genome construction

2021

Journal Article

Gram-Negative Neonatal Sepsis in Low- and Middle- Income Countries: How Appropriate are the WHO Recommended Empirical Sepsis Antibiotic Regimens? A Systematic Review and Meta-Analysis

Wen, Sophie C.H., Ezure, Yukiko, Rolley, Lauren, Spurling, Geoff, Lau, Colleen L., Paterson, David L. and Irwin, Adam D. (2021). Gram-Negative Neonatal Sepsis in Low- and Middle- Income Countries: How Appropriate are the WHO Recommended Empirical Sepsis Antibiotic Regimens? A Systematic Review and Meta-Analysis. SSRN Electronic Journal. doi: 10.2139/ssrn.3777180

Gram-Negative Neonatal Sepsis in Low- and Middle- Income Countries: How Appropriate are the WHO Recommended Empirical Sepsis Antibiotic Regimens? A Systematic Review and Meta-Analysis

2020

Journal Article

The relevance of probiotics in Caesarean-born neonates

Sidjabat, Hanna E., Alsaggaf, Alaa Mohammed Ali, Gopalakrishna, Akshatha, Nadar, Evelyn, Irwin, Adam and Koorts, Pieter (2020). The relevance of probiotics in Caesarean-born neonates. Microbiology Australia, 41 (2), 75-81. doi: 10.1071/ma20020

The relevance of probiotics in Caesarean-born neonates

2020

Conference Publication

Rapid and sensitive molecular detection of antimicrobial resistance (AMR); towards point-of-care testing in low resource settings

Ayfan, A., Ertl, N., Whiley, D., Paterson, D., Heney, C., Harris, P., Macdonald, J., Irwin, A. and Zowawi, H. (2020). Rapid and sensitive molecular detection of antimicrobial resistance (AMR); towards point-of-care testing in low resource settings. GCCMID 2019, Dubai, United Arab Emirates, 6-9 November 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jiph.2020.01.059

Rapid and sensitive molecular detection of antimicrobial resistance (AMR); towards point-of-care testing in low resource settings

2019

Journal Article

Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study

Warris, Adilia, Pana, Zoi-Dorothea, Oletto, Andrea, Lundin, Rebecca, Castagnola, Elio, Lehrnbecher, Thomas, Groll, Andreas H., Roilides, Emmanuel, Andersen, Cecilie T., Arendrup, Maiken C., Arsenijevic, Valentina Arsic, Bianchini, Sonia, von Both, Ulrich, Chmelnik, Martin, Controzzi, Tiziana, Emonts, Marieke, Esposito, Susanna, Ferreras-Antolin, Laura, Henriet, Stefanie, Iosifidis, Elias, Irwin, Adam, Kopsidas, John, Lagrou, Katrien, Lyall, Hermione, Casteleiro, Angela Manzanares, Mesini, Alessio, Olbrich, Peter, Paulus, Stephane, Lausch, Karen Rokkedal ... EUROCANDY Study Group (2019). Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study. The Pediatric Infectious Disease Journal, 39 (2), 1-120. doi: 10.1097/INF.0000000000002530

Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study

2019

Journal Article

Neonatal Antifungal Consumption Is Dominated by Prophylactic Use; Outcomes From The Pediatric Antifungal Stewardship: Optimizing Antifungal Prescription Study

Ferreras-Antolín, Laura, Irwin, Adam, Atra, Ayad, Dermirjian, Alicia, Drysdale, Simon B, Emonts, Marieke, McMaster, Paddy, Paulus, Stephane, Patel, Sanjay, Kinsey, Sally, Vergnano, Stefania, Whittaker, Elisabeth and Warris, Adilia (2019). Neonatal Antifungal Consumption Is Dominated by Prophylactic Use; Outcomes From The Pediatric Antifungal Stewardship: Optimizing Antifungal Prescription Study. The Pediatric infectious disease journal, 38 (12), 1-1223. doi: 10.1097/INF.0000000000002463

Neonatal Antifungal Consumption Is Dominated by Prophylactic Use; Outcomes From The Pediatric Antifungal Stewardship: Optimizing Antifungal Prescription Study

2019

Journal Article

Case ascertainment in active paediatric surveillance systems: a report from the British Paediatric Surveillance Unit Ascertainment Group

Lynn, Richard M, Reading, Richard, BPSU Ascertainment Group and Irwin, Adam (2019). Case ascertainment in active paediatric surveillance systems: a report from the British Paediatric Surveillance Unit Ascertainment Group. Archives of disease in childhood, 105 (1), 62-68. doi: 10.1136/archdischild-2019-317401

Case ascertainment in active paediatric surveillance systems: a report from the British Paediatric Surveillance Unit Ascertainment Group

2019

Journal Article

Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries

Hsia, Yingfen, Lee, Brian R., Versporten, Ann, Yang, Yonghong, Bielicki, Julia, Jackson, Charlotte, Newland, Jason, Goossens, Herman, Magrini, Nicola, Sharland, Mike, Teston, L., Cheung, K., Koning, S., Grimwood, K., Cross, J., da Silva, A., Benadof, D., Zhang, W. S., Zhao, W., Liu, G., Shen, K. L., Yao, K. H., Zheng, Y. J., Deng, J. K., Zhang, J. S., Wang, Y., Jiang, X. Y., Tian, D. Y., Jing, C. M. ... Gawrys, G. (2019). Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries. The Lancet Global Health, 7 (7), E861-E871. doi: 10.1016/S2214-109X(19)30071-3

Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries

2019

Journal Article

Revising paediatric vancomycin dosing accounting for nephrotoxicity in a pharmacokinetic-pharmacodynamic model

Kloprogge, Frank, Hill, Louise, Booth, John, Klein, Nigel, Irwin, Adam, Dixon, Garth and Standing, Joseph F (2019). Revising paediatric vancomycin dosing accounting for nephrotoxicity in a pharmacokinetic-pharmacodynamic model. Antimicrobial Agents and Chemotherapy, 63 (5) e00067-19. doi: 10.1128/aac.00067-19

Revising paediatric vancomycin dosing accounting for nephrotoxicity in a pharmacokinetic-pharmacodynamic model

2019

Journal Article

Detection of epidemic scarlet fever group A Streptococcus in Australia

Walker, Mark J., Brouwer, Stephan, Forde, Brian M., Worthing, Kate A., McIntyre, Liam, Sundac, Lana, Maloney, Sam, Roberts, Leah W., Barnett, Timothy C., Richter, Johanna, Cork, Amanda J., Irwin, Adam D., You, Yuanhai, Zhang, Jianzhong, Dougan, Gordon, Yuen, K. Y., Nizet, Victor, Beatson, Scott A., Grimwood, Keith and Davies, Mark R. (2019). Detection of epidemic scarlet fever group A Streptococcus in Australia. Clinical Infectious Diseases, 69 (7), 1232-1234. doi: 10.1093/cid/ciz099

Detection of epidemic scarlet fever group A Streptococcus in Australia

2019

Journal Article

A case for reduced frequency of CD4 count monitoring for children on combination antiretroviral therapy with consistently undetectable HIV viral load

Johnson, S. M., Standing, J. F., Klein, N., Irwin, A. D., Shingadia, D., Lonsdale, D. O., Gilmour, K. C., Flynn, J., Manns, C., Clapson, M. and Bamford, A. (2019). A case for reduced frequency of CD4 count monitoring for children on combination antiretroviral therapy with consistently undetectable HIV viral load. HIV Medicine, 20 (4), e8-e9. doi: 10.1111/hiv.12706

A case for reduced frequency of CD4 count monitoring for children on combination antiretroviral therapy with consistently undetectable HIV viral load

2019

Conference Publication

Neonatal observational vascular access (NOVA): an Australian audit

August, Deanne, Ullman, Amanda, New, Karen, McIntyre, Colette, Smith, Patricia, Koorts, Pieter, Irwin, Adam, Cobbald, Linda, Lack, Gill, Takashima, Mari, Foxcroft, Katie and Marsh, Nicole (2019). Neonatal observational vascular access (NOVA): an Australian audit. 3rd Congress of Joint European Neonatal Societies (jENS), Masstricht, Netherlands, 17-21 September 2019. New York, United States: Nature Publishing Group.

Neonatal observational vascular access (NOVA): an Australian audit

2019

Journal Article

Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children (vol 58, pg 53, 2019)

Boonsathorn, Sophida, Cheng, Iek, Kloprogge, Frank, Alonso, Carlos, Lee, Charmion, Doncheva, Bilyana, Booth, John, Chiesa, Robert, Irwin, Adam and Standing, Joseph F. (2019). Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children (vol 58, pg 53, 2019). Clinical Pharmacokinetics, 58 (1), 141-141. doi: 10.1007/s40262-018-0722-x

Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children (vol 58, pg 53, 2019)

2018

Journal Article

Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children

Boonsathorn, Sophida, Cheng, Iek, Kloprogge, Frank, Alonso, Carlos, Lee, Charmion, Doncheva, Bilyana, Booth, John, Chiesa, Robert, Irwin, Adam and Standing, Joseph F. (2018). Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children. Clinical Pharmacokinetics, 58 (1), 1-9. doi: 10.1007/s40262-018-0658-1

Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children

2018

Journal Article

Question 2: are three malaria tests necessary in children returning from the tropics with fever?

Wilson, Isabel Emily, Shingadia, Delane, Yeung, Shunmay, Riordan, Andrew and Irwin, Adam David (2018). Question 2: are three malaria tests necessary in children returning from the tropics with fever?. Archives of Disease in Childhood, 103 (1), 109-112. doi: 10.1136/archdischild-2017-313843

Question 2: are three malaria tests necessary in children returning from the tropics with fever?

2017

Journal Article

Acute infectious hepatitis in hospitalised children: a British Paediatric Surveillance Unit study

Braccio, Serena, Irwin, Adam, Riordan, Andrew, Shingadia, Delane, Kelly, Deirdre A., Bansal, Sanjay, Ramsay, Mary and Ladhani, Shamez N. (2017). Acute infectious hepatitis in hospitalised children: a British Paediatric Surveillance Unit study. Archives of Disease in Childhood, 102 (7), 624-628. doi: 10.1136/archdischild-2016-311916

Acute infectious hepatitis in hospitalised children: a British Paediatric Surveillance Unit study

2017

Conference Publication

A2.1  A comparison of metrics to evaluate trends in antimicrobial consumption in a tertiary children’s hospital

Kwok, M., Booth, J., Konstanty, P., Standing, J.F. and Irwin, A.D. (2017). A2.1  A comparison of metrics to evaluate trends in antimicrobial consumption in a tertiary children’s hospital. Great Ormond Street Hospital Conference, Nottingham, United Kingdom, 21–22 June, 2017. London, United Kingdom: BMJ Publishing Group. doi: 10.1136/archdischild-2017-084620.21

A2.1  A comparison of metrics to evaluate trends in antimicrobial consumption in a tertiary children’s hospital

2017

Journal Article

Predictors of fever-related admissions to a paediatric assessment unit, ward and reattendances in a South London emergency department: the CABIN 2 study

Bustinduy, Amaya L., Chis Ster, Irina, Shaw, Rebecca, Irwin, Adam, Thiagarajan, Jaiganesh, Beynon, Rhys, Ladhani, Shamez, Sharland, Mike and CABIN network (2017). Predictors of fever-related admissions to a paediatric assessment unit, ward and reattendances in a South London emergency department: the CABIN 2 study. Archives of Disease in Childhood, 102 (1), 22-28. doi: 10.1136/archdischild-2016-310494

Predictors of fever-related admissions to a paediatric assessment unit, ward and reattendances in a South London emergency department: the CABIN 2 study

2016

Journal Article

Supporting decisions to increase the safe discharge of children with febrile illness from the emergency department: a systematic review and meta-analysis

Irwin, A. D., Wickenden, J., Le Doare, K., Ladhani, S. and Sharland, M. (2016). Supporting decisions to increase the safe discharge of children with febrile illness from the emergency department: a systematic review and meta-analysis. e ADC, 101 (3), 259-66. doi: 10.1136/archdischild-2015-309056

Supporting decisions to increase the safe discharge of children with febrile illness from the emergency department: a systematic review and meta-analysis

Funding

Current funding

  • 2025 - 2030
    Comparison of Beta-Lactam Antibiotic Infusions in Septic Critically Ill Children: The BUILD Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2025 - 2030
    Comparison of Continuous and Extended vs Intermittent Beta-Lactam Infusions in Critically Ill Children with Sepsis ¿ the BUILD Multicentre Binational Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2024 - 2025
    Implementation of microsampling for routine clinical care of invasive infection in critically ill neonates (OPTIONS 2.0 and iOPTIONS sub-study) (RBWH SERTA grant led by MNHHS)
    Metro North Hospital and Health Service
    Open grant
  • 2024 - 2026
    Genomics of paediatric inborn errors of immunity
    TRI Leading Innovations through New Collaborations Scheme
    Open grant
  • 2023 - 2027
    Accelerating pathogen detection and antibiotic resistance prediction in children with suspected sepsis
    The Children's Hospital Foundation
    Open grant
  • 2023 - 2026
    Pharmacogenomics for better treatment of fungal infections in cancer
    MRFF Quality, Safety and Effectiveness of Medicine Use and Medicine Intervention by Pharmacists
    Open grant
  • 2023 - 2028
    Optimising the treatment of antibiotic resistant urinary tract infections in children: The FOSUTI Trial (MRFF CTA led by UNSYD)
    University of Sydney
    Open grant
  • 2021 - 2025
    Preventing adverse events during paediatric cancer treatment: A multi-site hybrid randomised controlled trial of innovative catheter lock solutions
    Cancer Council Queensland
    Open grant
  • 2021 - 2026
    ARC Training Centre for Information Resilience
    ARC Industrial Transformation Training Centres
    Open grant
  • 2021 - 2025
    Overcoming the barriers to treatment of multi-drug resistant Gram-negative bloodstream infections in Australian children
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2023
    The co-design and delivery of a state-wide paediatric sepsis pathway
    Children's Health Queensland Hospital and Health Service
    Open grant
  • 2022 - 2024
    The 3,000 Genomes project: using machine learning and artificial intelligence for robust culture-independent susceptibility testing
    Heidi-CSIRO IDR and AMR Projects
    Open grant
  • 2021 - 2022
    Preventing healthcare acquired, ventilator- associated conditions in the PICU: Implementation of new airway clearance guidance
    The Children's Hospital Foundation
    Open grant
  • 2020 - 2021
    Reducing acute severe respiratory events in health care workers during the Covid-19 pandemic with OM85
    NHMRC MRFF Coronavirus Research Response
    Open grant
  • 2020 - 2023
    The development of an integrated molecular diagnostic pathway to optimise the treatment of cytomegalovirus in children undergoing haematopoietic stem cell transplant
    The Children's Hospital Foundation
    Open grant
  • 2020 - 2021
    Understanding the clinical and molecular epidemiology of Gram-negative bloodstream infections to improve outcomes in Australian children
    The Children's Hospital Foundation
    Open grant
  • 2019 - 2021
    Virulence and detection of Escherichia coli that cause neonatal meningitis
    The Children's Hospital Foundation
    Open grant
  • 2019 - 2021
    Rapid point-of-care tests for multidrug resistant bacteria tailored for QLD paediatrics
    The Children's Hospital Foundation
    Open grant
  • 2019 - 2020
    Optimising the treatment of invasive infection in critically ill neonates, through application of an innovative microsampling approach
    Metro North Hospital and Health Service
    Open grant
  • 2018 - 2020
    An innovative Antimicrobial Stewardship Program for children in remote and regional areas: optimising antibiotic use through early intravenous-to-oral conversion
    The Children's Hospital Foundation
    Open grant
  • 2018 - 2019
    Sakzewski Core Translational Research Group
    The Children's Hospital Foundation
    Open grant

Supervision

Availability

Associate Professor Adam Irwin is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

Media

Enquiries

Contact Associate Professor Adam Irwin directly for media enquiries about:

  • Antimicrobial resistance
  • Childhood infections
  • Sepsis

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