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Featured 2021 Journal Article Gram-negative neonatal sepsis in low- and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta-analysisWen, Sophie C. H., Ezure, Yukiko, Rolley, Lauren, Spurling, Geoff, Lau, Colleen L., Riaz, Saba, Paterson, David L. and Irwin, Adam D. (2021). Gram-negative neonatal sepsis in low- and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta-analysis. PLoS Medicine, 18 (9) e1003787, 1-20. doi: 10.1371/journal.pmed.1003787 |
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Featured 2021 Journal Article The use of continuous electronic prescribing data to infer trends in antimicrobial consumption and estimate the impact of stewardship interventions in hospitalized childrenChannon-Wells, S., Kwok, M., Booth, J., Bamford, A., Konstanty, P., Hatcher, J., Dixon, G., Diggle, P. J., Standing, J. F. and Irwin, A. D. (2021). The use of continuous electronic prescribing data to infer trends in antimicrobial consumption and estimate the impact of stewardship interventions in hospitalized children. Journal of Antimicrobial Chemotherapy, 76 (9), 2464-2471. doi: 10.1093/jac/dkab187 |
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Featured 2017 Journal Article Predicting risk of serious bacterial infections in febrile children in the emergency departmentIrwin, Adam D, Grant, Alison, Williams, Rhian, Kolamunnage-Dona, Ruwanthi, Drew, Richard J, Paulus, Stephane, Jeffers, Graham, Williams, Kim, Breen, Rachel, Preston, Jennifer, Appelbe, Duncan, Chesters, Christine, Newland, Paul, Marzouk, Omnia, McNamara, Paul S, Diggle, Peter J and Carrol, Enitan D (2017). Predicting risk of serious bacterial infections in febrile children in the emergency department. Pediatrics, 140 (2) e20162853, e20162853. doi: 10.1542/peds.2016-2853 |
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2025 Journal Article Corrigendum to “The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions” [Aust Crit Care 35 (2022) 651–660]Schults, Jessica, Charles, Karina, Long, Debbie, Brown, Georgia, Copnell, Beverley, Dargaville, Peter, Davies, Kylie, Erikson, Simon, Forrest, Kate, Harnischfeger, Jane, Irwin, Adam, Kendrick, Tina, Lake, Anna, Ntoumenopoulos, George, Waak, Michaela, Woodard, Mark, Tume, Lyvonne, Cooke, Marie, Mitchell, Marion, Hall, Lisa and Ullman, Amanda (2025). Corrigendum to “The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions” [Aust Crit Care 35 (2022) 651–660]. Australian Critical Care, 38 (4) 101224, 101224. doi: 10.1016/j.aucc.2025.101224 |
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2025 Journal Article Impact of a statewide sepsis pathway on quality of antibiotic use in children in the Emergency DepartmentIrwin, Adam D., Graham, Nicolette, Gartrell, Kyana, Fletchett, Emily, Cross, Jack, Doyle, Kayla, Owen, Kieran, Seaton, Robert, Rice, Michael, Lane, Paul, Ergetu, Endrias, Gilholm, Patricia, Gibbons, Kristen S., Raman, Sainath, Harley, Amanda, Lister, Paula, Grimwood, Keith, Schlapbach, Luregn J., on behalf of the Queensland Statewide Sepsis Collaborative, Redpath, Lyndell, Mason, Donna, Kalke, Vikrant, Mehta, Naitik, Taylor, Scott and Bell, Anna (2025). Impact of a statewide sepsis pathway on quality of antibiotic use in children in the Emergency Department. Intensive Care Medicine – Paediatric and Neonatal, 3 (1) 11, 1-10. doi: 10.1007/s44253-025-00060-x |
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2025 Journal Article A flexible framework for minimal biomarker signature discovery from clinical omics studies without library size normalisationRawlinson, Daniel, Zhou, Chenxi, Kaforou, Myrsini, Cao, Kim-Anh Lê, Coin, Lachlan J. M., RAPIDS Study Group, Irwin, Adam and Gibbons, Kristen (2025). A flexible framework for minimal biomarker signature discovery from clinical omics studies without library size normalisation. PLoS Digital Health, 4 (3) e0000780, 1-24. doi: 10.1371/journal.pdig.0000780 |
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2025 Journal Article Impact of COVID-19 on antimicrobial stewardship activities in hospitalised children: a scoping reviewMohammed, Zabiuddin Ahad, Grant, Gary, Irwin, Adam D., Hattingh, Laetitia, Kalwaje Eshwara, Vandana, Okonkwo, Rose I. and Khan, Sohil (2025). Impact of COVID-19 on antimicrobial stewardship activities in hospitalised children: a scoping review. Journal of Paediatrics and Child Health, 61 (3), 333-343. doi: 10.1111/jpc.16786 |
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2025 Journal Article Identification of distinct clinical profiles of sepsis risk in paediatric emergency department patients using Bayesian profile regressionGilholm, Patricia, Raman, Sainath, Irwin, Adam, Lister, Paula, Harley, Amanda, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Identification of distinct clinical profiles of sepsis risk in paediatric emergency department patients using Bayesian profile regression. BMJ Paediatrics Open, 9 (1) e003100, e003100-1. doi: 10.1136/bmjpo-2024-003100 |
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2025 Journal Article A rapid molecular detection tool for toxigenic M1UK Streptococcus pyogenesBrouwer, Stephan, Das, Swairindhree, Hayes, Andrew J., Bertolla, Olivia M., Davies, Mark R., Walker, Mark J., Whiley, David M., Irwin, Adam D. and Tickner, Jacob A. (2025). A rapid molecular detection tool for toxigenic M1UK Streptococcus pyogenes. The Journal of Infectious Diseases, 231 (2), e375-e384. doi: 10.1093/infdis/jiae437 |
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2025 Journal Article Antimicrobial resistance in Staphylococcus aureus and Enterococci spp. isolates from bloodstream infections in Australian children, 2013 - 2021Williams, Anita, Coombs, Geoffrey W., Bell, Jan M., Daley, Denise A., Mowlaboccus, Shakeel, Bryant, Penelope, Campbell, Anita, Cooley, Louise, Iredell, Jon, Irwin, Adam D., Kesson, Alison, McMullan, Brendan, Warner, Morgyn S., Williams, Phoebe and Blyth, Christopher C. (2025). Antimicrobial resistance in Staphylococcus aureus and Enterococci spp. isolates from bloodstream infections in Australian children, 2013 - 2021. Journal of the Pediatric Infectious Diseases Society, 14 (2) piae110. doi: 10.1093/jpids/piae110 |
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2025 Journal Article P-812. Not Little Adults: Key Differences in Antimicrobial Resistance in Australian Bloodstream Isolates between Children and Adults, 2020-2021Williams, Anita, Coombs, Geoff W, Bell, Jan, Daley, Denise A, Mowlaboccus, Shakeel, Bryant, Penelope A, Campbell, Anita Jane, Cooley, Louise, Howard-Jones, Annaleise, Iredell, Jon, Irwin, Adam D, McMullan, Brendan, Warner, Morgyn, Williams, Phoebe and Blyth, Christopher C (2025). P-812. Not Little Adults: Key Differences in Antimicrobial Resistance in Australian Bloodstream Isolates between Children and Adults, 2020-2021. Open Forum Infectious Diseases, 12 (Supplement_1). doi: 10.1093/ofid/ofae631.1004 |
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2025 Journal Article Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric SepsisGilholm, Patricia, Lister, Paula, Irwin, Adam, Harley, Amanda, Raman, Sainath, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis. Maternal and Child Health Journal, 1-10. doi: 10.1007/s10995-025-04038-1 |
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2025 Conference Publication Diagnosing pediatric sepsis with septicyte rapid host gene expressionZimmerman, Jerry, Schlapbach, Luregn, Gibbons, Kristen, Cermelli, Silvia, Coin, Lachlan, Davis, Roy, Irwin, Adam, George, Shane, Navalkar, Krupa, Raman, Sainath, Yager, Thomas and Brandon, Richard (2025). Diagnosing pediatric sepsis with septicyte rapid host gene expression. 2025 Critical Care Congress, Orlando, FL United States, 23-25 February 2025. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/01.ccm.0001104996.00108.d9 |
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2024 Conference Publication EMIT - event-based masked auto encoding for irregular time seriesPatel, Hrishikesh, Qiu, Ruihong, Irwin, Adam, Sadiq, Shazia and Wang, Sen (2024). EMIT - event-based masked auto encoding for irregular time series. 2024 IEEE International Conference on Data Mining (ICDM), Abu Dhabi, United Arab Emirates, 9-12 December 2024. Piscataway, NJ, United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/icdm59182.2024.00044 |
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2024 Journal Article Antimicrobial resistance in Enterobacterales, Acinetobacter spp. and Pseudomonas aeruginosa isolates from bloodstream infections in Australian children, 2013-2021Williams, Anita, Coombs, Geoffrey W., Bell, Jan M., Daley, Denise A., Mowlaboccus, Shakeel, Bryant, Penelope, Campbell, Anita, Cooley, Louise, Iredell, Jon, Irwin, Adam D., Kesson, Alison, McMullan, Brendan, Warner, Morgyn S., Williams, Phoebe and Blyth, Christopher C. (2024). Antimicrobial resistance in Enterobacterales, Acinetobacter spp. and Pseudomonas aeruginosa isolates from bloodstream infections in Australian children, 2013-2021. Journal of the Pediatric Infectious Diseases Society, 13 (12), 617-625. doi: 10.1093/jpids/piae111 |
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2024 Conference Publication Development Of A ‘Train The Trainer’ Paediatric Sepsis Education Package To Support Local EducatorsMoore, C., English, A., Harley, A., Irwin, A., O’Keefe, M., Raman, S. and Lister, Paula (2024). Development Of A ‘Train The Trainer’ Paediatric Sepsis Education Package To Support Local Educators. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001085136.74096.8a |
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Featured 2024 Journal Article Trends in Enterobacterales Bloodstream Infections in ChildrenGibbs, Anna A.M., Laupland, Kevin B., Edwards, Felicity, Ling, Weiping, Channon-Wells, Samuel, Harley, David, Falster, Kathleen, Paterson, David L., Harris, Patrick N.A. and Irwin, Adam D. (2024). Trends in Enterobacterales Bloodstream Infections in Children. Pediatrics, 154 (4) e2023063532. doi: 10.1542/peds.2023-063532 |
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2024 Journal Article Serum ganciclovir drug exposure in children receiving standard ganciclovir dosingYang, Wenyu, Irwin, Adam, Weerdenburg, Heather, McWhinney, Brett, Cole, Theresa, Lei, Alice, Han, Bing, Zhu, Xiao and Gwee, Amanda (2024). Serum ganciclovir drug exposure in children receiving standard ganciclovir dosing. Antimicrobial Agents and Chemotherapy, 68 (10) e0052524. doi: 10.1128/aac.00525-24 |
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2024 Journal Article Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomesWen, Sophie C. H., Harris, Patrick N. A., Forde, Brian, Permana, Budi, Chatfield, Mark D., Lau, Colleen L., Spurling, Geoffrey, Bauer, Michelle J., Balch, Ross, Chambers, Henry, Schlapbach, Luregn J., Clark, Julia E., Dougherty, Sonia, Blyth, Christopher C., Britton, Philip N., Clifford, Vanessa, Haeusler, Gabrielle M., McMullan, Brendan, Wadia, Ushma, Paterson, David L., Irwin, Adam D., on behalf of the PAEDS network, Carr, Jeremy, Vasilunas, Nan, Francis, Joshua R., Macartney, Kristine, Crawford, Nigel W., Wood, Nicholas, Buttery, Jim ... Glover, Catherine (2024). Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes. Clinical Infectious Diseases, 79 (3), 734-743. doi: 10.1093/cid/ciae341 |
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2024 Journal Article Getting up to speed: Rapid pathogen and antimicrobial resistance diagnostics in sepsisLiborio, Mariana P., Harris, Patrick N. A., Ravi, Chitra and Irwin, Adam D. (2024). Getting up to speed: Rapid pathogen and antimicrobial resistance diagnostics in sepsis. Microorganisms, 12 (9) 1824, 1-29. doi: 10.3390/microorganisms12091824 |
