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2025 Journal Article Antimicrobial resistance in Staphylococcus aureus and Enterococci spp. isolates from bloodstream infections in Australian children, 2013 - 2021Williams, Anita, Coombs, Geoffrey W., Bell, Jan M., Daley, Denise A., Mowlaboccus, Shakeel, Bryant, Penelope, Campbell, Anita, Cooley, Louise, Iredell, Jon, Irwin, Adam D., Kesson, Alison, McMullan, Brendan, Warner, Morgyn S., Williams, Phoebe and Blyth, Christopher C. (2025). Antimicrobial resistance in Staphylococcus aureus and Enterococci spp. isolates from bloodstream infections in Australian children, 2013 - 2021. Journal of the Pediatric Infectious Diseases Society, 14 (2) piae110. doi: 10.1093/jpids/piae110 |
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2025 Conference Publication Not Little Adults: Key Differences in Antimicrobial Resistance in Australian Bloodstream Isolates between Children and Adults, 2020-2021Williams, Anita, Coombs, Geoff W., Bell, Jan, Daley, Denise A., Mowlaboccus, Shakeel, Bryant, Penelope A., Campbell, Anita Jane, Cooley, Louise, Howard-Jones, Annaleise, Iredell, Jon, Irwin, Adam D., McMullan, Brendan, Warner, Morgyn, Williams, Phoebe and Blyth, Christopher C. (2025). Not Little Adults: Key Differences in Antimicrobial Resistance in Australian Bloodstream Isolates between Children and Adults, 2020-2021. IDWeek 2024, Los Angeles, CA United States, 16-19 October 2024. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofae631.1004 |
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2025 Journal Article Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric SepsisGilholm, Patricia, Lister, Paula, Irwin, Adam, Harley, Amanda, Raman, Sainath, Schlapbach, Luregn J. and Gibbons, Kristen S. (2025). Comparison of Random Forest and Stepwise Regression for Variable Selection Using Low Prevalence Predictors: A case Study in Paediatric Sepsis. Maternal and Child Health Journal, 29 (5), 1-10. doi: 10.1007/s10995-025-04038-1 |
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2025 Conference Publication Diagnosing pediatric sepsis with septicyte rapid host gene expressionZimmerman, Jerry, Schlapbach, Luregn, Gibbons, Kristen, Cermelli, Silvia, Coin, Lachlan, Davis, Roy, Irwin, Adam, George, Shane, Navalkar, Krupa, Raman, Sainath, Yager, Thomas and Brandon, Richard (2025). Diagnosing pediatric sepsis with septicyte rapid host gene expression. 2025 Critical Care Congress, Orlando, FL United States, 23-25 February 2025. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/01.ccm.0001104996.00108.d9 |
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2024 Conference Publication EMIT - event-based masked auto encoding for irregular time seriesPatel, Hrishikesh, Qiu, Ruihong, Irwin, Adam, Sadiq, Shazia and Wang, Sen (2024). EMIT - event-based masked auto encoding for irregular time series. 2024 IEEE International Conference on Data Mining (ICDM), Abu Dhabi, United Arab Emirates, 9-12 December 2024. Piscataway, NJ, United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/icdm59182.2024.00044 |
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2024 Journal Article Antimicrobial resistance in Enterobacterales, Acinetobacter spp. and Pseudomonas aeruginosa isolates from bloodstream infections in Australian children, 2013-2021Williams, Anita, Coombs, Geoffrey W., Bell, Jan M., Daley, Denise A., Mowlaboccus, Shakeel, Bryant, Penelope, Campbell, Anita, Cooley, Louise, Iredell, Jon, Irwin, Adam D., Kesson, Alison, McMullan, Brendan, Warner, Morgyn S., Williams, Phoebe and Blyth, Christopher C. (2024). Antimicrobial resistance in Enterobacterales, Acinetobacter spp. and Pseudomonas aeruginosa isolates from bloodstream infections in Australian children, 2013-2021. Journal of the Pediatric Infectious Diseases Society, 13 (12), 617-625. doi: 10.1093/jpids/piae111 |
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2024 Conference Publication Development Of A ‘Train The Trainer’ Paediatric Sepsis Education Package To Support Local EducatorsMoore, C., English, A., Harley, A., Irwin, A., O’Keefe, M., Raman, S. and Lister, Paula (2024). Development Of A ‘Train The Trainer’ Paediatric Sepsis Education Package To Support Local Educators. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001085136.74096.8a |
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2024 Journal Article Trends in Enterobacterales Bloodstream Infections in ChildrenGibbs, Anna A.M., Laupland, Kevin B., Edwards, Felicity, Ling, Weiping, Channon-Wells, Samuel, Harley, David, Falster, Kathleen, Paterson, David L., Harris, Patrick N.A. and Irwin, Adam D. (2024). Trends in Enterobacterales Bloodstream Infections in Children. Pediatrics, 154 (4) e2023063532, 1-11. doi: 10.1542/peds.2023-063532 |
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2024 Journal Article Serum ganciclovir drug exposure in children receiving standard ganciclovir dosingYang, Wenyu, Irwin, Adam, Weerdenburg, Heather, McWhinney, Brett, Cole, Theresa, Lei, Alice, Han, Bing, Zhu, Xiao and Gwee, Amanda (2024). Serum ganciclovir drug exposure in children receiving standard ganciclovir dosing. Antimicrobial Agents and Chemotherapy, 68 (10) e0052524, e0052524. doi: 10.1128/aac.00525-24 |
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2024 Journal Article Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomesWen, Sophie C. H., Harris, Patrick N. A., Forde, Brian, Permana, Budi, Chatfield, Mark D., Lau, Colleen L., Spurling, Geoffrey, Bauer, Michelle J., Balch, Ross, Chambers, Henry, Schlapbach, Luregn J., Clark, Julia E., Dougherty, Sonia, Blyth, Christopher C., Britton, Philip N., Clifford, Vanessa, Haeusler, Gabrielle M., McMullan, Brendan, Wadia, Ushma, Paterson, David L., Irwin, Adam D., on behalf of the PAEDS network, Carr, Jeremy, Vasilunas, Nan, Francis, Joshua R., Macartney, Kristine, Crawford, Nigel W., Wood, Nicholas, Buttery, Jim ... Glover, Catherine (2024). Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes. Clinical Infectious Diseases, 79 (3), 734-743. doi: 10.1093/cid/ciae341 |
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2024 Journal Article Getting up to speed: Rapid pathogen and antimicrobial resistance diagnostics in sepsisLiborio, Mariana P., Harris, Patrick N. A., Ravi, Chitra and Irwin, Adam D. (2024). Getting up to speed: Rapid pathogen and antimicrobial resistance diagnostics in sepsis. Microorganisms, 12 (9) 1824, 1-29. doi: 10.3390/microorganisms12091824 |
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2024 Journal Article Australian Group on Antimicrobial Research surveillance outcome programs - bloodstream infections and antimicrobial resistance patterns from patients less than 18 years of age, January 2020 - December 2021Williams, Anita, Coombs, Geoffrey W, Bell, Jan, Daley, Denise A, Mowlaboccus, Shakeel, Bryant, Penelope A, Campbell, Anita J, Cooley, Louise, Iredell, Jon, Irwin, Adam D, Kesson, Alison, McMullan, Brendan, Warner, Morgyn S, Williams, Phoebe and Blyth, Christoper C (2024). Australian Group on Antimicrobial Research surveillance outcome programs - bloodstream infections and antimicrobial resistance patterns from patients less than 18 years of age, January 2020 - December 2021. Communicable diseases intelligence (2018), 48 32. doi: 10.33321/cdi.2024.48.32 |
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2024 Journal Article Preventing adverse events during paediatric cancer treatment: protocol for a multi-site hybrid randomised controlled trial of catheter lock solutions (the CLOCK trial)Ullman, Amanda, Takashima, Mari, Gibson, Victoria, Comber, Elouise, Borello, Eloise, Bradford, Natalie, Byrnes, Joshua, Cole, Roni, Eisenstat, David, Henson, Nicole, Howard, Philippa, Irwin, Adam, Keogh, Samantha, Kleidon, Tricia, Martin, Michelle, McCleary, Karen, McLean, Jordana, Moloney, Susan, Monagle, Paul, Moore, Andrew, Newall, Fiona, Noyes, Michelle, Rowan, Gemma, St John, Amanda, Wood, Andrew, Wolf, Joshua and Ware, Robert (2024). Preventing adverse events during paediatric cancer treatment: protocol for a multi-site hybrid randomised controlled trial of catheter lock solutions (the CLOCK trial). BMJ Open, 14 (7) e085637, 1-9. doi: 10.1136/bmjopen-2024-085637 |
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2024 Journal Article Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort studySchlapbach, Luregn J., Ganesamoorthy, Devika, Wilson, Clare, Raman, Sainath, George, Shane, Snelling, Peter J., Phillips, Natalie, Irwin, Adam, Sharp, Natalie, Le Marsney, Renate, Chavan, Arjun, Hempenstall, Allison, Bialasiewicz, Seweryn, MacDonald, Anna D., Grimwood, Keith, Cling, Jessica C., McPherson, Stephen J., Blumenthal, Antje, Kaforou, Myrsini, Levin, Michael, Herberg, Jethro A., Gibbons, Kristen S., Coin, Lachlan J. M., EUCLIDS consortium and RAPIDS Study Group (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child and Adolescent Health, 8 (5), 325-338. doi: 10.1016/S2352-4642(24)00017-8 |
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2024 Journal Article Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsisKhan, Nemat, Kumar, Vinod, Li, Pengcheng, RAPIDS Study Group, Raman, Sainath (RSG member), Sharp, Natalie (RSG member), Phillips, Natalie (RSG member), Irwin, Adam (RSG member), George, Shane (RSG member), Grimwood, Keith (RSG member), Snelling, Peter (RSG member), Chavan, Arjun (RSG member), Hempenstall, Allison (RSG member), Gibbons, Kristen (RSG member), Le Marsney, Renate (RSG member), Blumenthal, Antje (RSG member), Ganesamoorthy, Devika (RSG member), Coin, Lachlan (RSG member), Schlapbach, Luregn J., Boyd, Andrew W., Coulthard, Mark G. and Woodruff, Trent M. (2024). Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Science Translational Medicine, 16 (744) eadg5768, 1-15. doi: 10.1126/scitranslmed.adg5768 |
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2024 Journal Article High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infectionNhu, Nguyen Thi Khanh, Phan, Minh-Duy, Hancock, Steven J., Peters, Kate M., Alvarez-Fraga, Laura, Forde, Brian M., Andersen, Stacey B., Miliya, Thyl, Harris, Patrick N. A., Beatson, Scott A., Schlebusch, Sanmarie, Bergh, Haakon, Turner, Paul, Brauner, Annelie, Westerlund-Wikström, Benita, Irwin, Adam D. and Schembri, Mark A (2024). High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection. eLife, 12 RP91853. doi: 10.7554/elife.91853.3 |
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2024 Journal Article Correction: achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsisChai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Correction: achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (5), 810-810. doi: 10.1007/s00134-024-07393-9 |
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2024 Journal Article Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsisChai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 539-547. doi: 10.1007/s00134-024-07353-3 |
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2024 Journal Article A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteriaNhu, Nguyen Thi Khanh, Rahman, M. Arifur, Goh, Kelvin G. K., Kim, Seung Jae, Phan, Minh-Duy, Peters, Kate M., Alvarez-Fraga, Laura, Hancock, Steven J., Ravi, Chitra, Kidd, Timothy J., Sullivan, Matthew J., Irvine, Katharine M., Beatson, Scott A., Sweet, Matthew J., Irwin, Adam D., Vukovic, Jana, Ulett, Glen C., Hasnain, Sumaira Z. and Schembri, Mark A. (2024). A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria. Nature Communications, 15 (1) 1441, 1441. doi: 10.1038/s41467-024-45176-4 |
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2024 Journal Article Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort studyMcWhinney, Brett, Ungerer, Jacobus, LeMarsey, Renate, Phillips, Natalie, Raman, Sainath, Gibbons, Kristen, Schlapbach, Luregn J., on behalf of Rapid Acute Paediatric Infection Diagnosis in Suspected Sepsis (RAPIDS) Study Investigators, Irwin, Adam (RAPIDS member) and Bialasiewicz, Seweryn (RAPIDS member) (2024). Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study. Pediatric Critical Care Medicine, 25 (2), 171-176. doi: 10.1097/PCC.0000000000003349 |
