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2022

Conference Publication

Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department

Gilholm, P., Irwin, A., Lister, P., Harley, A., Raman, S., Schlapbach, L. J. and Gibbons, K. (2022). Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department. 11th Congress of the World Federation of Pediatric Intensive & Critical Care Societies, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899876.46317.ec

Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department

2022

Journal Article

Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility

Ayfan, Abdulrahman K. S., Macdonald, Joanne, Irwin, Adam D., Zowawi, Hosam M., Forde, Brian M., Paterson, David L., Lahra, Monica M. and Whiley, David M. (2022). Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility. Journal of Antimicrobial Chemotherapy, 77 (11), 2933-2936. doi: 10.1093/jac/dkac242

Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility

2022

Journal Article

Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia

Blythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6

Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia

2022

Journal Article

An innovative Antimicrobial Stewardship Program for children in remote and regional areas in Queensland, Australia: optimizing antibiotic use through timely intravenous-to-oral conversion

Avent, M.L., Lee, X.J., Irwin, A.D., Graham, N., Brain, D., Fejzic, J., van Driel, M. and Clark, J.E. (2022). An innovative Antimicrobial Stewardship Program for children in remote and regional areas in Queensland, Australia: optimizing antibiotic use through timely intravenous-to-oral conversion. Journal of Global Antimicrobial Resistance, 28, 53-58. doi: 10.1016/j.jgar.2021.11.014

An innovative Antimicrobial Stewardship Program for children in remote and regional areas in Queensland, Australia: optimizing antibiotic use through timely intravenous-to-oral conversion

2022

Journal Article

Neonatal vascular access practice and complications : An observational study of 1,375 catheter days

McIntyre, Colette, August, Deanne, Cobbald, Linda, Lack, Gill, Takashima, Mari, Foxcroft, Katie, Marsh, Nicole, Smith, Patricia, New, Karen, Koorts, Pieter, Irwin, Adam and Ullman, Amanda (2022). Neonatal vascular access practice and complications : An observational study of 1,375 catheter days. Journal of Perinatal and Neonatal Nursing, 37 (4), 332-339. doi: 10.1097/jpn.0000000000000589

Neonatal vascular access practice and complications : An observational study of 1,375 catheter days

2022

Journal Article

Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study

Parker, Suzanne L., Irwin, Adam D., Hosking, Francine, August, Deanne, Schoenmaker, Brittany, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Davies, Mark W. (2022). Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study. International Journal of Antimicrobial Agents, 59 (2) 106513, 1-2. doi: 10.1016/j.ijantimicag.2021.106513

Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study

2021

Journal Article

Treatment of cutaneous leishmaniasis in a nonendemic country: a case series of children in Australia

Hill, Nicholas, Irwin, Adam, Graham, Nicolette, Leung, Clare, Francis, Joshua R., Wall, Nerilee and Nourse, Clare (2021). Treatment of cutaneous leishmaniasis in a nonendemic country: a case series of children in Australia. The Pediatric Infectious Disease Journal, 41 (4), e177-e181. doi: 10.1097/inf.0000000000003445

Treatment of cutaneous leishmaniasis in a nonendemic country: a case series of children in Australia

2021

Journal Article

The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions

Schults, Jessica, Charles, Karina, Long, Debbie, Brown, Georgia, Copnell, Beverley, Dargaville, Peter, Davies, Kylie, Erikson, Simon, Forrest, Kate, Harnischfeger, Jane, Irwin, Adam, Kendrik, Tina, Lake, Anna, Ntoumenopoulos, George, Waak, Michaela, Woodard, Mark, Tume, Lyvonne, Cooke, Marie, Mitchell, Marion, Hall, Lisa and Ullman, Amanda (2021). The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions. Australian Critical Care, 35 (6), 651-660. doi: 10.1016/j.aucc.2021.10.005

The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions

2021

Journal Article

Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program

Raman, Sainath, English, Alana, O'Keefe, Meagan, Harley, Amanda, Steele, Mary, Minogue, Jess, Weller, Kate, Long, Debbie, Irwin, Adam and Lister, Paula (2021). Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program. Frontiers in Pediatrics, 9 759234, 759234. doi: 10.3389/fped.2021.759234

Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program

2021

Journal Article

Pediatric antifungal prescribing patterns identify significant opportunities to rationalize antifungal use in children

Ferreras-Antolín, Laura, Irwin, Adam, Atra, Ayad, Chapelle, Faye, Drysdale, Simon B., Emonts, Marieke, McMaster, Paddy, Paulus, Stephane, Patel, Sanjay, Rompola, Menie, Vergnano, Stefania, Whittaker, Elizabeth and Warris, Adilia (2021). Pediatric antifungal prescribing patterns identify significant opportunities to rationalize antifungal use in children. The Pediatric Infectious Disease Journal, 41 (3), e69-e74. doi: 10.1097/INF.0000000000003402

Pediatric antifungal prescribing patterns identify significant opportunities to rationalize antifungal use in children

2021

Journal Article

Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department

Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573

Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department

2021

Journal Article

Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study

Venkatesh, Balasubramanian, Schlapbach, Luregn, Mason, Donna, Wilks, Kathryn, Seaton, Robert, Lister, Paula, Irwin, Adam, Lane, Paul, Redpath, Lyndell, Gibbons, Kristen, Ergetu, Endrias and Rice, Michael (2021). Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study. The Lancet Regional Health - Western Pacific, 18 100305, 100305. doi: 10.1016/j.lanwpc.2021.100305

Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study

2021

Conference Publication

Recommendations for endotracheal suction interventions in children with highly infectious respiratory disease: results from a RAND/UCLA binational appropriateness panel

Schults, Jessica, Charles, Karina, Long, Debbie, Erikson, Simon, Irwin, Adam, Waak, Michaela, Hall, Lisa and Ullman, Amanda (2021). Recommendations for endotracheal suction interventions in children with highly infectious respiratory disease: results from a RAND/UCLA binational appropriateness panel. 9th International Australasian College for Infection Prevention and Control (ACIPC) online conference, Online, 7-10 November 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.idh.2021.09.031

Recommendations for endotracheal suction interventions in children with highly infectious respiratory disease: results from a RAND/UCLA binational appropriateness panel

2021

Journal Article

Paediatric Active Enhanced Disease Surveillance (PAEDS) 2019: Prospective hospital-based surveillance for serious paediatric conditions

Dinsmore, Nicole, McRae, Jocelynne E., Quinn, Helen E., Glover, Catherine, Dougherty, Sonia, McMinn, Allissa, Crawford, Nigel, Marshall, Helen, Carlson, Samantha J, Blyth, Christopher, Lucas, Ryan, Irwin, Adam, Macartney, Kristine, Britton, Philip N, Wood, Nicholas and The Paediatric Active Enhanced Disease Surveillance network (2021). Paediatric Active Enhanced Disease Surveillance (PAEDS) 2019: Prospective hospital-based surveillance for serious paediatric conditions. Communicable Diseases Intelligence, 45, 1-24. doi: 10.33321/cdi.2021.45.53

Paediatric Active Enhanced Disease Surveillance (PAEDS) 2019: Prospective hospital-based surveillance for serious paediatric conditions

2021

Journal Article

MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction

Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction. BMC Genomics, 22 (1) 474, 474. doi: 10.1186/s12864-021-07767-z

MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction

2021

Journal Article

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

2021

Journal Article

New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care

Peri, Anna Maria, Stewart, Adam, Hume, Anna, Irwin, Adam and Harris, Patrick N A (2021). New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care. Current Infectious Disease Reports, 23 (8) 12, 12. doi: 10.1007/s11908-021-00755-0

New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care

2021

Journal Article

Role of C reactive protein and procalcitonin in the diagnosis of lower respiratory tract infection in children in the outpatient setting

Pérez-López, Andrés, Irwin, Adam, Rodrigo, Carlos and Prat-Aymerich, Cristina (2021). Role of C reactive protein and procalcitonin in the diagnosis of lower respiratory tract infection in children in the outpatient setting. BMJ, 373 (11) n1409, n1409. doi: 10.1136/bmj.n1409

Role of C reactive protein and procalcitonin in the diagnosis of lower respiratory tract infection in children in the outpatient setting

2021

Journal Article

Normal saline and lung recruitment with paediatric endotracheal suction (NARES): a pilot, factorial, randomised controlled trial

Schults, Jessica A., Cooke, Marie, Long, Debbie, Schibler, Andreas, Ware, Robert S., Charles, Karina, Irwin, Adam and Mitchell, Marion L. (2021). Normal saline and lung recruitment with paediatric endotracheal suction (NARES): a pilot, factorial, randomised controlled trial. Australian Critical Care, 34 (6), 530-538. doi: 10.1016/j.aucc.2021.01.006

Normal saline and lung recruitment with paediatric endotracheal suction (NARES): a pilot, factorial, randomised controlled trial

2021

Journal Article

Rapid detection of NDM and VIM carbapenemase encoding genes by recombinase polymerase amplification and lateral flow–based detection

Ayfan, Abdulrahman K. S., Macdonald, Joanne, Harris, Patrick N. A., Heney, Claire, Paterson, David L., Trembizki, Ella, Wang, Claire Y. T., Whiley, David M., Zowawi, Hosam M. and Irwin, Adam D. (2021). Rapid detection of NDM and VIM carbapenemase encoding genes by recombinase polymerase amplification and lateral flow–based detection. European Journal of Clinical Microbiology & Infectious Diseases, 40 (11), 2447-2453. doi: 10.1007/s10096-021-04267-6

Rapid detection of NDM and VIM carbapenemase encoding genes by recombinase polymerase amplification and lateral flow–based detection