|
2021 Journal Article Gram-negative neonatal sepsis in low- and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta-analysisWen, Sophie C. H., Ezure, Yukiko, Rolley, Lauren, Spurling, Geoff, Lau, Colleen L., Riaz, Saba, Paterson, David L. and Irwin, Adam D. (2021). Gram-negative neonatal sepsis in low- and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta-analysis. PLoS Medicine, 18 (9) e1003787, 1-20. doi: 10.1371/journal.pmed.1003787 |
|
2021 Journal Article The use of continuous electronic prescribing data to infer trends in antimicrobial consumption and estimate the impact of stewardship interventions in hospitalized childrenChannon-Wells, S., Kwok, M., Booth, J., Bamford, A., Konstanty, P., Hatcher, J., Dixon, G., Diggle, P. J., Standing, J. F. and Irwin, A. D. (2021). The use of continuous electronic prescribing data to infer trends in antimicrobial consumption and estimate the impact of stewardship interventions in hospitalized children. Journal of Antimicrobial Chemotherapy, 76 (9), 2464-2471. doi: 10.1093/jac/dkab187 |
|
2017 Journal Article Predicting risk of serious bacterial infections in febrile children in the emergency departmentIrwin, Adam D, Grant, Alison, Williams, Rhian, Kolamunnage-Dona, Ruwanthi, Drew, Richard J, Paulus, Stephane, Jeffers, Graham, Williams, Kim, Breen, Rachel, Preston, Jennifer, Appelbe, Duncan, Chesters, Christine, Newland, Paul, Marzouk, Omnia, McNamara, Paul S, Diggle, Peter J and Carrol, Enitan D (2017). Predicting risk of serious bacterial infections in febrile children in the emergency department. Pediatrics, 140 (2) e20162853, e20162853. doi: 10.1542/peds.2016-2853 |
|
2024 Journal Article Getting up to speed: Rapid pathogen and antimicrobial resistance diagnostics in sepsisLiborio, Mariana P., Harris, Patrick N. A., Ravi, Chitra and Irwin, Adam D. (2024). Getting up to speed: Rapid pathogen and antimicrobial resistance diagnostics in sepsis. Microorganisms, 12 (9) 1824, 1-29. doi: 10.3390/microorganisms12091824 |
|
2024 Journal Article A rapid molecular detection tool for toxigenic M1UK Streptococcus pyogenesBrouwer, Stephan, Das, Swairindhree, Hayes, Andrew J., Bertolla, Olivia M., Davies, Mark R., Walker, Mark J., Whiley, David M., Irwin, Adam D. and Tickner, Jacob A. (2024). A rapid molecular detection tool for toxigenic M1UK Streptococcus pyogenes. The Journal of Infectious Diseases. doi: 10.1093/infdis/jiae437 |
|
2024 Journal Article Australian Group on Antimicrobial Research surveillance outcome programs - bloodstream infections and antimicrobial resistance patterns from patients less than 18 years of age, January 2020 - December 2021Williams, Anita, Coombs, Geoffrey W, Bell, Jan, Daley, Denise A, Mowlaboccus, Shakeel, Bryant, Penelope A, Campbell, Anita J, Cooley, Louise, Iredell, Jon, Irwin, Adam D, Kesson, Alison, McMullan, Brendan, Warner, Morgyn S, Williams, Phoebe and Blyth, Christoper C (2024). Australian Group on Antimicrobial Research surveillance outcome programs - bloodstream infections and antimicrobial resistance patterns from patients less than 18 years of age, January 2020 - December 2021. Communicable diseases intelligence (2018), 48 ARTN 32. doi: 10.33321/cdi.2024.48.32 |
|
2024 Journal Article Preventing adverse events during paediatric cancer treatment: protocol for a multi-site hybrid randomised controlled trial of catheter lock solutions (the CLOCK trial)Ullman, Amanda, Takashima, Mari, Gibson, Victoria, Comber, Elouise, Borello, Eloise, Bradford, Natalie, Byrnes, Joshua, Cole, Roni, Eisenstat, David, Henson, Nicole, Howard, Philippa, Irwin, Adam, Keogh, Samantha, Kleidon, Tricia, Martin, Michelle, McCleary, Karen, McLean, Jordana, Moloney, Susan, Monagle, Paul, Moore, Andrew, Newall, Fiona, Noyes, Michelle, Rowan, Gemma, St John, Amanda, Wood, Andrew, Wolf, Joshua and Ware, Robert (2024). Preventing adverse events during paediatric cancer treatment: protocol for a multi-site hybrid randomised controlled trial of catheter lock solutions (the CLOCK trial). BMJ Open, 14 (7) e085637, e085637-9. doi: 10.1136/bmjopen-2024-085637 |
|
2024 Journal Article Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomesWen, Sophie C.H., Harris, Patrick N. A., Forde, Brian, Permana, Budi, Chatfield, Mark D., Lau, Colleen L., Spurling, Geoffrey, Bauer, Michelle J., Balch, Ross, Chambers, Henry, Schlapbach, Luregn J., Clark, Julia E., Dougherty, Sonia, Blyth, Christopher C., Britton, Philip N., Clifford, Vanessa, Haeusler, Gabrielle M., McMullan, Brendan, Wadia, Ushma, Paterson, David L., Irwin, Adam D., on behalf of the PAEDS network, Carr, Jeremy, Vasilunas, Nan, Francis, Joshua R., Macartney, Kristine, Crawford, Nigel W., Wood, Nicholas, Buttery, Jim ... Glover, Catherine (2024). Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes. Clinical Infectious Diseases. doi: 10.1093/cid/ciae341 |
|
2024 Journal Article Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort studySchlapbach, Luregn J., Ganesamoorthy, Devika, Wilson, Clare, Raman, Sainath, George, Shane, Snelling, Peter J., Phillips, Natalie, Irwin, Adam, Sharp, Natalie, Le Marsney, Renate, Chavan, Arjun, Hempenstall, Allison, Bialasiewicz, Seweryn, MacDonald, Anna D., Grimwood, Keith, Cling, Jessica C., McPherson, Stephen J., Blumenthal, Antje, Kaforou, Myrsini, Levin, Michael, Herberg, Jethro A., Gibbons, Kristen S., Coin, Lachlan J. M., EUCLIDS consortium and RAPIDS Study Group (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child and Adolescent Health, 8 (5), 325-338. doi: 10.1016/S2352-4642(24)00017-8 |
|
2024 Journal Article Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsisKhan, Nemat, Kumar, Vinod, Li, Pengcheng, RAPIDS Study Group, Raman, Sainath (RSG member), Sharp, Natalie (RSG member), Irwin, Adam (RSG member), Phillips, Natalie (RSG member), George, Shane (RSG member), Grimwood, Keith (RSG member), Snelling, Peter (RSG member), Chavan, Arjun (RSG member), Hempenstall, Allison (RSG member), Gibbons, Kristen (RSG member), Le Marsney, Renate (RSG member), Blumenthal, Antje (RSG member), Ganesamoorthy, Devika (RSG member), Coin, Lachlan (RSG member), Schlapbach, Luregn J., Boyd, Andrew W., Coulthard, Mark G. and Woodruff, Trent M. (2024). Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Science Translational Medicine, 16 (744) eadg5768, 1-15. doi: 10.1126/scitranslmed.adg5768 |
|
2024 Journal Article High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infectionNhu, Nguyen Thi Khanh, Phan, Minh-Duy, Hancock, Steven J., Peters, Kate M., Alvarez-Fraga, Laura, Forde, Brian M., Andersen, Stacey B., Miliya, Thyl, Harris, Patrick N. A., Beatson, Scott A., Schlebusch, Sanmarie, Bergh, Haakon, Turner, Paul, Brauner, Annelie, Westerlund-Wikström, Benita, Irwin, Adam D. and Schembri, Mark A (2024). High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection. eLife, 12 ARTN RP91853. doi: 10.7554/elife.91853.3 |
|
2024 Journal Article Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsisChai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (5), 810-810. doi: 10.1007/s00134-024-07393-9 |
|
2024 Journal Article Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsisChai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 1-9. doi: 10.1007/s00134-024-07353-3 |
|
2024 Journal Article A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteriaNhu, Nguyen Thi Khanh, Rahman, M. Arifur, Goh, Kelvin G. K., Kim, Seung Jae, Phan, Minh-Duy, Peters, Kate M., Alvarez-Fraga, Laura, Hancock, Steven J., Ravi, Chitra, Kidd, Timothy J., Sullivan, Matthew J., Irvine, Katharine M., Beatson, Scott A., Sweet, Matthew J., Irwin, Adam D., Vukovic, Jana, Ulett, Glen C., Hasnain, Sumaira Z. and Schembri, Mark A. (2024). A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria. Nature Communications, 15 (1) 1441, 1441. doi: 10.1038/s41467-024-45176-4 |
|
2024 Journal Article Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort studyMcWhinney, Brett, Ungerer, Jacobus, LeMarsey, Renate, Phillips, Natalie, Raman, Sainath, Gibbons, Kristen, Schlapbach, Luregn J., on behalf of Rapid Acute Paediatric Infection Diagnosis in Suspected Sepsis (RAPIDS) Study Investigators and Irwin, Adam (RAPIDS member) (2024). Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study. Pediatric Critical Care Medicine, 25 (2), 171-176. doi: 10.1097/PCC.0000000000003349 |
|
2024 Journal Article Prevalence of extra-pulmonary tuberculosis in Africa: a systematic review and meta-analysisHailu, Semira, Hurst, Cameron, Cyphers, Griffin, Thottunkal, Stefan, Harley, David, Viney, Kerri, Irwin, Adam, Dean, Judith and Nourse, Clare (2024). Prevalence of extra-pulmonary tuberculosis in Africa: a systematic review and meta-analysis. Tropical Medicine & International Health, 29 (4), 257-265. doi: 10.1111/tmi.13970 |
|
2024 Journal Article Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsisHarris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology spectrum, 12 (2) e0306523, e0306523. doi: 10.1128/spectrum.03065-23 |
|
2023 Journal Article Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infectionsSchults, Jessica A., Charles, Karina R., Harnischfeger, Jane, Ware, Robert S., Royle, Ruth H., Byrnes, Joshua M., Long, Debbie A., Ullman, Amanda J., Raman, Sainath, Waak, Michaela, Lake, Anna, Cooke, Marie, Irwin, Adam, Tume, Lyvonne and Hall, Lisa (2023). Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infections. Australian Critical Care, 37 (1), 1-9. doi: 10.1016/j.aucc.2023.09.008 |
|
2023 Journal Article The opportunities and challenges for artificial intelligence to improve sepsis outcomes in the paediatric intensive care unitAslan, Abdullah Tarik, Permana, Budi, Harris, Patrick N. A., Naidoo, Kuban D., Pienaar, Michael A. and Irwin, Adam D. (2023). The opportunities and challenges for artificial intelligence to improve sepsis outcomes in the paediatric intensive care unit. Current Infectious Disease Reports, 25 (11), 243-253. doi: 10.1007/s11908-023-00818-4 |
|
2023 Journal Article Challenges Facing PICUs in Low- and Middle-Income Countries in the Treatment of Emerging Multidrug-Resistant Organisms: a Review and Perspective from a South African PICUSaggers, Robin T., Mothibi, Lesego M., Irwin, Adam D. and Naidoo, Kuban D. (2023). Challenges Facing PICUs in Low- and Middle-Income Countries in the Treatment of Emerging Multidrug-Resistant Organisms: a Review and Perspective from a South African PICU. Current Infectious Disease Reports, 25 (11), 1-10. doi: 10.1007/s11908-023-00817-5 |
