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2024 Journal Article Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsisChai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 539-547. doi: 10.1007/s00134-024-07353-3 |
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2024 Journal Article A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteriaNhu, Nguyen Thi Khanh, Rahman, M. Arifur, Goh, Kelvin G. K., Kim, Seung Jae, Phan, Minh-Duy, Peters, Kate M., Alvarez-Fraga, Laura, Hancock, Steven J., Ravi, Chitra, Kidd, Timothy J., Sullivan, Matthew J., Irvine, Katharine M., Beatson, Scott A., Sweet, Matthew J., Irwin, Adam D., Vukovic, Jana, Ulett, Glen C., Hasnain, Sumaira Z. and Schembri, Mark A. (2024). A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria. Nature Communications, 15 (1) 1441, 1441. doi: 10.1038/s41467-024-45176-4 |
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2024 Journal Article Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort studyMcWhinney, Brett, Ungerer, Jacobus, LeMarsey, Renate, Phillips, Natalie, Raman, Sainath, Gibbons, Kristen, Schlapbach, Luregn J., on behalf of Rapid Acute Paediatric Infection Diagnosis in Suspected Sepsis (RAPIDS) Study Investigators, Irwin, Adam (RAPIDS member) and Bialasiewicz, Seweryn (RAPIDS member) (2024). Serum levels of vitamin C and thiamin in children with suspected sepsis: a prospective observational cohort study. Pediatric Critical Care Medicine, 25 (2), 171-176. doi: 10.1097/PCC.0000000000003349 |
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2024 Journal Article Prevalence of extra-pulmonary tuberculosis in Africa: a systematic review and meta-analysisHailu, Semira, Hurst, Cameron, Cyphers, Griffin, Thottunkal, Stefan, Harley, David, Viney, Kerri, Irwin, Adam, Dean, Judith and Nourse, Clare (2024). Prevalence of extra-pulmonary tuberculosis in Africa: a systematic review and meta-analysis. Tropical Medicine & International Health, 29 (4), 257-265. doi: 10.1111/tmi.13970 |
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2024 Journal Article Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsisHarris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology Spectrum, 12 (2) e0306523, 1-16. doi: 10.1128/spectrum.03065-23 |
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2023 Journal Article Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infectionsSchults, Jessica A., Charles, Karina R., Harnischfeger, Jane, Ware, Robert S., Royle, Ruth H., Byrnes, Joshua M., Long, Debbie A., Ullman, Amanda J., Raman, Sainath, Waak, Michaela, Lake, Anna, Cooke, Marie, Irwin, Adam, Tume, Lyvonne and Hall, Lisa (2023). Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infections. Australian Critical Care, 37 (1), 1-9. doi: 10.1016/j.aucc.2023.09.008 |
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2023 Journal Article The opportunities and challenges for artificial intelligence to improve sepsis outcomes in the paediatric intensive care unitAslan, Abdullah Tarik, Permana, Budi, Harris, Patrick N. A., Naidoo, Kuban D., Pienaar, Michael A. and Irwin, Adam D. (2023). The opportunities and challenges for artificial intelligence to improve sepsis outcomes in the paediatric intensive care unit. Current Infectious Disease Reports, 25 (11), 243-253. doi: 10.1007/s11908-023-00818-4 |
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2023 Journal Article Challenges Facing PICUs in Low- and Middle-Income Countries in the Treatment of Emerging Multidrug-Resistant Organisms: a Review and Perspective from a South African PICUSaggers, Robin T., Mothibi, Lesego M., Irwin, Adam D. and Naidoo, Kuban D. (2023). Challenges Facing PICUs in Low- and Middle-Income Countries in the Treatment of Emerging Multidrug-Resistant Organisms: a Review and Perspective from a South African PICU. Current Infectious Disease Reports, 25 (11), 1-10. doi: 10.1007/s11908-023-00817-5 |
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2023 Journal Article Application of the ViroKey® SQ FLEX assay for detection of cytomegalovirus antiviral resistanceHume, Jocelyn, Lowry, Kym, Whiley, David M., Irwin, Adam D., Bletchly, Cheryl and Sweeney, Emma L. (2023). Application of the ViroKey® SQ FLEX assay for detection of cytomegalovirus antiviral resistance. Journal of Clinical Virology, 167 105556, 1-8. doi: 10.1016/j.jcv.2023.105556 |
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2023 Journal Article Cytomegalovirus in children undergoing haematopoietic stem cell transplantation: a diagnostic and therapeutic approach to antiviral resistanceHume, Jocelyn, Sweeney, Emma L., Lowry, Kym, Fraser, Chris, Clark, Julia E., Whiley, David M. and Irwin, Adam D. (2023). Cytomegalovirus in children undergoing haematopoietic stem cell transplantation: a diagnostic and therapeutic approach to antiviral resistance. Frontiers in Pediatrics, 11 1180392, 1180392. doi: 10.3389/fped.2023.1180392 |
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2023 Journal Article A multicentre, retrospective audit of fosfomycin use for urinary tract infections in Australian children and adolescentsPurcell, Rachael, Yeoh, Daniel, Bowen, Asha, Britton, Philip N., Carr, Jeremy P., Chen, Ming, Cheung, Kaman, Clark, Julia, Irwin, Adam, Lai, Tony, Lorenzen, Ulrik, Steer, Andrew, Wen, Sophie, Williams, Phoebe, Yap, Natalie, Cooper, Celia and Gwee, Amanda (2023). A multicentre, retrospective audit of fosfomycin use for urinary tract infections in Australian children and adolescents. Journal of Antimicrobial Chemotherapy, 78 (7), 1-6. doi: 10.1093/jac/dkad131 |
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2023 Journal Article Rapid molecular detection of CMY-2, and CTX-M group 1 and 9 variants via recombinase polymerase amplificationErtl, Nicole G., Irwin, Adam D., Macdonald, Joanne, Bauer, Michelle J., Wang, Claire Y. T., Harris, Patrick N. A., Heney, Claire, Zowawi, Hosam M. and Whiley, David M. (2023). Rapid molecular detection of CMY-2, and CTX-M group 1 and 9 variants via recombinase polymerase amplification. JAC - Antimicrobial Resistance, 5 (2) dlad023, dlad023. doi: 10.1093/jacamr/dlad023 |
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2023 Journal Article Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeADavies, Mark R., Keller, Nadia, Brouwer, Stephan, Jespersen, Magnus G., Cork, Amanda J., Hayes, Andrew J., Pitt, Miranda E., De Oliveira, David M. P., Harbison-Price, Nichaela, Bertolla, Olivia M., Mediati, Daniel G., Curren, Bodie F., Taiaroa, George, Lacey, Jake A., Smith, Helen V., Fang, Ning-Xia, Coin, Lachlan J. M., Stevens, Kerrie, Tong, Steven Y. C., Sanderson-Smith, Martina, Tree, Jai J., Irwin, Adam D., Grimwood, Keith, Howden, Benjamin P., Jennison, Amy V. and Walker, Mark J. (2023). Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA. Nature Communications, 14 (1) 1051, 1-12. doi: 10.1038/s41467-023-36717-4 |
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2023 Journal Article Evolving insights into the epidemiology of Moraxella species bloodstream infection from two decades of surveillance in Queensland, AustraliaSchults, Jessica, Edwards, Felicity, Charles, Karina, Irwin, Adam D., Rickard, Claire M., Harris, Patrick N. A., Paterson, David L. and Laupland, Kevin (2023). Evolving insights into the epidemiology of Moraxella species bloodstream infection from two decades of surveillance in Queensland, Australia. European Journal of Clinical Microbiology and Infectious Diseases, 42 (2), 209-216. doi: 10.1007/s10096-022-04540-2 |
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2023 Journal Article Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, AustraliaGilholm, Patricia, Gibbons, Kristen, Lister, Paula, Harley, Amanda, Irwin, Adam, Raman, Sainath, Rice, Michael, Schlapbach, Luregn J. and Queensland Statewide Sepsis Collaborative (2023). Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia. BMJ Open, 13 (1) e061431, 1-25. doi: 10.1136/bmjopen-2022-061431 |
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2023 Journal Article Nystatin is commonly prescribed as prophylaxis in children beyond the neonatal ageJayawardena-Thabrew, Harshani, Warris, Adilia, PASOAP Group , Irwin, Adam and Ferreras-Antolin, Laura (2023). Nystatin is commonly prescribed as prophylaxis in children beyond the neonatal age. Medical Mycology, 61 (1) myac097. doi: 10.1093/mmy/myac097 |
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2022 Journal Article Improving paediatric antimicrobial stewardship in remote and regional Queensland hospitals: development and qualitative evaluation of a tailored intervention for intravenous-to-oral antibiotic switchingSharman, Leah S., Avent, Minyon L., Lyall, Vivian, Fejzic, Jasmina, Clark, Julia E., Irwin, Adam, Graham, Nicolette and van Driel, Mieke L. (2022). Improving paediatric antimicrobial stewardship in remote and regional Queensland hospitals: development and qualitative evaluation of a tailored intervention for intravenous-to-oral antibiotic switching. BMJ Open, 12 (12) e064888, 1-10. doi: 10.1136/bmjopen-2022-064888 |
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2022 Journal Article Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibilityAyfan, Abdulrahman K. S., Macdonald, Joanne, Irwin, Adam D., Zowawi, Hosam M., Forde, Brian M., Paterson, David L., Lahra, Monica M. and Whiley, David M. (2022). Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility. Journal of Antimicrobial Chemotherapy, 77 (11), 2933-2936. doi: 10.1093/jac/dkac242 |
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2022 Journal Article Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, AustraliaBlythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6 |
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2022 Journal Article An innovative Antimicrobial Stewardship Program for children in remote and regional areas in Queensland, Australia: optimizing antibiotic use through timely intravenous-to-oral conversionAvent, M.L., Lee, X.J., Irwin, A.D., Graham, N., Brain, D., Fejzic, J., van Driel, M. and Clark, J.E. (2022). An innovative Antimicrobial Stewardship Program for children in remote and regional areas in Queensland, Australia: optimizing antibiotic use through timely intravenous-to-oral conversion. Journal of Global Antimicrobial Resistance, 28, 53-58. doi: 10.1016/j.jgar.2021.11.014 |
