Overview
Background
Dr Adam Irwin is a Principal Research Fellow in Paediatric Infectious Diseases at The University of Queensland and Queensland Children’s Hospital in Brisbane, Australia. His research focuses on the early recognition of invasive infections and sepsis, and the optimal use of antimicrobials in children. He is the medical co-chair of the Queensland Paediatric Sepsis Program which was awarded a Global Sepsis Alliance award in 2020, and Queensland Health Excellence awards in 2022 for Healthcare Delivery and Consumer Engagement, and a member of the Australian Group on Antimicrobial Resistance-Kids Steering Committee. He is a recipient of a National Health and Medical Research Council Emerging Leadership Fellowship to investigate the management of multi-drug resistant gram-negative infections in children.
Adam studied at the University of Birmingham Medical School and completed training in Paediatric Infectious Disease and Immunology in London. He was awarded his PhD by the University of Liverpool Institute of Infection and Global Health in 2016. Prior to relocating to Queensland, he was secretary of the British Paediatric Allergy, Immunity and Infection Group.
Availability
- Associate Professor Adam Irwin is:
- Available for supervision
- Media expert
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Birmingham
- Doctor of Philosophy, University of Liverpool
Works
Search Professor Adam Irwin’s works on UQ eSpace
2021
Conference Publication
Recommendations for endotracheal suction interventions in children with highly infectious respiratory disease: results from a RAND/UCLA binational appropriateness panel
Schults, Jessica, Charles, Karina, Long, Debbie, Erikson, Simon, Irwin, Adam, Waak, Michaela, Hall, Lisa and Ullman, Amanda (2021). Recommendations for endotracheal suction interventions in children with highly infectious respiratory disease: results from a RAND/UCLA binational appropriateness panel. 9th International Australasian College for Infection Prevention and Control (ACIPC) online conference, Online, 7-10 November 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.idh.2021.09.031
2021
Journal Article
Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department
Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573
2021
Journal Article
Paediatric Active Enhanced Disease Surveillance (PAEDS) 2019: Prospective hospital-based surveillance for serious paediatric conditions
Dinsmore, Nicole, McRae, Jocelynne E., Quinn, Helen E., Glover, Catherine, Dougherty, Sonia, McMinn, Allissa, Crawford, Nigel, Marshall, Helen, Carlson, Samantha J, Blyth, Christopher, Lucas, Ryan, Irwin, Adam, Macartney, Kristine, Britton, Philip N, Wood, Nicholas and The Paediatric Active Enhanced Disease Surveillance network (2021). Paediatric Active Enhanced Disease Surveillance (PAEDS) 2019: Prospective hospital-based surveillance for serious paediatric conditions. Communicable Diseases Intelligence, 45, 1-24. doi: 10.33321/cdi.2021.45.53
2021
Journal Article
MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction
Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction. BMC Genomics, 22 (1) 474, 474. doi: 10.1186/s12864-021-07767-z
2021
Journal Article
Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)
Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680
2021
Journal Article
New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care
Peri, Anna Maria, Stewart, Adam, Hume, Anna, Irwin, Adam and Harris, Patrick N A (2021). New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care. Current Infectious Disease Reports, 23 (8) 12, 12. doi: 10.1007/s11908-021-00755-0
2021
Journal Article
Role of C reactive protein and procalcitonin in the diagnosis of lower respiratory tract infection in children in the outpatient setting
Pérez-López, Andrés, Irwin, Adam, Rodrigo, Carlos and Prat-Aymerich, Cristina (2021). Role of C reactive protein and procalcitonin in the diagnosis of lower respiratory tract infection in children in the outpatient setting. BMJ, 373 (11) n1409, n1409. doi: 10.1136/bmj.n1409
2021
Journal Article
Normal saline and lung recruitment with paediatric endotracheal suction (NARES): a pilot, factorial, randomised controlled trial
Schults, Jessica A., Cooke, Marie, Long, Debbie, Schibler, Andreas, Ware, Robert S., Charles, Karina, Irwin, Adam and Mitchell, Marion L. (2021). Normal saline and lung recruitment with paediatric endotracheal suction (NARES): a pilot, factorial, randomised controlled trial. Australian Critical Care, 34 (6), 530-538. doi: 10.1016/j.aucc.2021.01.006
2021
Journal Article
Rapid detection of NDM and VIM carbapenemase encoding genes by recombinase polymerase amplification and lateral flow–based detection
Ayfan, Abdulrahman K. S., Macdonald, Joanne, Harris, Patrick N. A., Heney, Claire, Paterson, David L., Trembizki, Ella, Wang, Claire Y. T., Whiley, David M., Zowawi, Hosam M. and Irwin, Adam D. (2021). Rapid detection of NDM and VIM carbapenemase encoding genes by recombinase polymerase amplification and lateral flow–based detection. European Journal of Clinical Microbiology & Infectious Diseases, 40 (11), 2447-2453. doi: 10.1007/s10096-021-04267-6
2021
Journal Article
Gram-Negative Neonatal Sepsis in Low- and Middle- Income Countries: How Appropriate are the WHO Recommended Empirical Sepsis Antibiotic Regimens? A Systematic Review and Meta-Analysis
Wen, Sophie C.H., Ezure, Yukiko, Rolley, Lauren, Spurling, Geoff, Lau, Colleen L., Paterson, David L. and Irwin, Adam D. (2021). Gram-Negative Neonatal Sepsis in Low- and Middle- Income Countries: How Appropriate are the WHO Recommended Empirical Sepsis Antibiotic Regimens? A Systematic Review and Meta-Analysis. SSRN Electronic Journal. doi: 10.2139/ssrn.3777180
2020
Journal Article
The relevance of probiotics in Caesarean-born neonates
Sidjabat, Hanna E., Alsaggaf, Alaa Mohammed Ali, Gopalakrishna, Akshatha, Nadar, Evelyn, Irwin, Adam and Koorts, Pieter (2020). The relevance of probiotics in Caesarean-born neonates. Microbiology Australia, 41 (2), 75-81. doi: 10.1071/ma20020
2020
Conference Publication
Rapid and sensitive molecular detection of antimicrobial resistance (AMR); towards point-of-care testing in low resource settings
Ayfan, A., Ertl, N., Whiley, D., Paterson, D., Heney, C., Harris, P., Macdonald, J., Irwin, A. and Zowawi, H. (2020). Rapid and sensitive molecular detection of antimicrobial resistance (AMR); towards point-of-care testing in low resource settings. GCCMID 2019, Dubai, United Arab Emirates, 6-9 November 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jiph.2020.01.059
2019
Journal Article
Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study
Warris, Adilia, Pana, Zoi-Dorothea, Oletto, Andrea, Lundin, Rebecca, Castagnola, Elio, Lehrnbecher, Thomas, Groll, Andreas H., Roilides, Emmanuel, Andersen, Cecilie T., Arendrup, Maiken C., Arsenijevic, Valentina Arsic, Bianchini, Sonia, von Both, Ulrich, Chmelnik, Martin, Controzzi, Tiziana, Emonts, Marieke, Esposito, Susanna, Ferreras-Antolin, Laura, Henriet, Stefanie, Iosifidis, Elias, Irwin, Adam, Kopsidas, John, Lagrou, Katrien, Lyall, Hermione, Casteleiro, Angela Manzanares, Mesini, Alessio, Olbrich, Peter, Paulus, Stephane, Lausch, Karen Rokkedal ... EUROCANDY Study Group (2019). Etiology and Outcome of Candidemia in Neonates and Children in Europe: An 11-year Multinational Retrospective Study. The Pediatric Infectious Disease Journal, 39 (2), 1-120. doi: 10.1097/INF.0000000000002530
2019
Journal Article
Neonatal Antifungal Consumption Is Dominated by Prophylactic Use; Outcomes From The Pediatric Antifungal Stewardship: Optimizing Antifungal Prescription Study
Ferreras-Antolín, Laura, Irwin, Adam, Atra, Ayad, Dermirjian, Alicia, Drysdale, Simon B, Emonts, Marieke, McMaster, Paddy, Paulus, Stephane, Patel, Sanjay, Kinsey, Sally, Vergnano, Stefania, Whittaker, Elisabeth and Warris, Adilia (2019). Neonatal Antifungal Consumption Is Dominated by Prophylactic Use; Outcomes From The Pediatric Antifungal Stewardship: Optimizing Antifungal Prescription Study. The Pediatric infectious disease journal, 38 (12), 1-1223. doi: 10.1097/INF.0000000000002463
2019
Journal Article
Case ascertainment in active paediatric surveillance systems: a report from the British Paediatric Surveillance Unit Ascertainment Group
Lynn, Richard M, Reading, Richard, BPSU Ascertainment Group and Irwin, Adam (2019). Case ascertainment in active paediatric surveillance systems: a report from the British Paediatric Surveillance Unit Ascertainment Group. Archives of disease in childhood, 105 (1), 62-68. doi: 10.1136/archdischild-2019-317401
2019
Journal Article
Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries
Hsia, Yingfen, Lee, Brian R., Versporten, Ann, Yang, Yonghong, Bielicki, Julia, Jackson, Charlotte, Newland, Jason, Goossens, Herman, Magrini, Nicola, Sharland, Mike, Teston, L., Cheung, K., Koning, S., Grimwood, K., Cross, J., da Silva, A., Benadof, D., Zhang, W. S., Zhao, W., Liu, G., Shen, K. L., Yao, K. H., Zheng, Y. J., Deng, J. K., Zhang, J. S., Wang, Y., Jiang, X. Y., Tian, D. Y., Jing, C. M. ... Gawrys, G. (2019). Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries. The Lancet Global Health, 7 (7), E861-E871. doi: 10.1016/S2214-109X(19)30071-3
2019
Journal Article
Revising paediatric vancomycin dosing accounting for nephrotoxicity in a pharmacokinetic-pharmacodynamic model
Kloprogge, Frank, Hill, Louise, Booth, John, Klein, Nigel, Irwin, Adam, Dixon, Garth and Standing, Joseph F (2019). Revising paediatric vancomycin dosing accounting for nephrotoxicity in a pharmacokinetic-pharmacodynamic model. Antimicrobial Agents and Chemotherapy, 63 (5) e00067-19. doi: 10.1128/aac.00067-19
2019
Journal Article
Detection of epidemic scarlet fever group A Streptococcus in Australia
Walker, Mark J., Brouwer, Stephan, Forde, Brian M., Worthing, Kate A., McIntyre, Liam, Sundac, Lana, Maloney, Sam, Roberts, Leah W., Barnett, Timothy C., Richter, Johanna, Cork, Amanda J., Irwin, Adam D., You, Yuanhai, Zhang, Jianzhong, Dougan, Gordon, Yuen, K. Y., Nizet, Victor, Beatson, Scott A., Grimwood, Keith and Davies, Mark R. (2019). Detection of epidemic scarlet fever group A Streptococcus in Australia. Clinical Infectious Diseases, 69 (7), 1232-1234. doi: 10.1093/cid/ciz099
2019
Journal Article
A case for reduced frequency of CD4 count monitoring for children on combination antiretroviral therapy with consistently undetectable HIV viral load
Johnson, S. M., Standing, J. F., Klein, N., Irwin, A. D., Shingadia, D., Lonsdale, D. O., Gilmour, K. C., Flynn, J., Manns, C., Clapson, M. and Bamford, A. (2019). A case for reduced frequency of CD4 count monitoring for children on combination antiretroviral therapy with consistently undetectable HIV viral load. HIV Medicine, 20 (4), e8-e9. doi: 10.1111/hiv.12706
2019
Conference Publication
Neonatal observational vascular access (NOVA): an Australian audit
August, Deanne, Ullman, Amanda, New, Karen, McIntyre, Colette, Smith, Patricia, Koorts, Pieter, Irwin, Adam, Cobbald, Linda, Lack, Gill, Takashima, Mari, Foxcroft, Katie and Marsh, Nicole (2019). Neonatal observational vascular access (NOVA): an Australian audit. 3rd Congress of Joint European Neonatal Societies (jENS), Masstricht, Netherlands, 17-21 September 2019. New York, United States: Nature Publishing Group.
Funding
Current funding
Supervision
Availability
- Associate Professor Adam Irwin is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Gram-negative bloodstream infections in Australian children
Principal Advisor
Other advisors: Dr Geoff Spurling, Professor Colleen Lau, Mr Mark Chatfield
-
Doctor Philosophy
Accelerating pathogen detection and antibiotic resistance prediction in children with suspected sepsis.
Principal Advisor
Other advisors: Dr Patrick Harris
-
Doctor Philosophy
Rapid detection of AMR targets using isothermal technology
Associate Advisor
Other advisors: Associate Professor David Whiley
-
Doctor Philosophy
Expanding Data Sets to Allow Improved Critical Care for Children - Outpatient Risk Prediction
Associate Advisor
Other advisors: Professor Shazia Sadiq, Associate Professor Sen Wang
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Doctor Philosophy
The development of an integrated molecular diagnostic pathway to optimise the treatment of cytomegalovirus in children undergoing haematopoietic stem cell transplant
Associate Advisor
Other advisors: Dr Kym Lowry, Associate Professor David Whiley, Dr Emma Sweeney
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Doctor Philosophy
Improving Sepsis Management through Better Data and Rapid Learning
Associate Advisor
Other advisors: Professor Andrew Burton-Jones, Dr Ida Asadi Someh, Professor Marta Indulska
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Doctor Philosophy
The Burden of Extrapulmonary Tuberculosis in Africa
Associate Advisor
Other advisors: Associate Professor David Harley, Professor Clare Nourse, Associate Professor Judith Dean
Media
Enquiries
Contact Associate Professor Adam Irwin directly for media enquiries about:
- Antimicrobial resistance
- Childhood infections
- Sepsis
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