Overview
Background
Dr Adam Irwin is a Principal Research Fellow in Paediatric Infectious Diseases at The University of Queensland and Queensland Children’s Hospital in Brisbane, Australia. His research focuses on the early recognition of invasive infections and sepsis, and the optimal use of antimicrobials in children. He is the medical co-chair of the Queensland Paediatric Sepsis Program which was awarded a Global Sepsis Alliance award in 2020, and Queensland Health Excellence awards in 2022 for Healthcare Delivery and Consumer Engagement, and a member of the Australian Group on Antimicrobial Resistance-Kids Steering Committee. He is a recipient of a National Health and Medical Research Council Emerging Leadership Fellowship to investigate the management of multi-drug resistant gram-negative infections in children.
Adam studied at the University of Birmingham Medical School and completed training in Paediatric Infectious Disease and Immunology in London. He was awarded his PhD by the University of Liverpool Institute of Infection and Global Health in 2016. Prior to relocating to Queensland, he was secretary of the British Paediatric Allergy, Immunity and Infection Group.
Availability
- Associate Professor Adam Irwin is:
- Available for supervision
- Media expert
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Birmingham
- Doctor of Philosophy, University of Liverpool
Works
Search Professor Adam Irwin’s works on UQ eSpace
2022
Conference Publication
Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department
Gilholm, P., Irwin, A., Lister, P., Harley, A., Raman, S., Schlapbach, L. J. and Gibbons, K. (2022). Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department. 11th Congress of the World Federation of Pediatric Intensive & Critical Care Societies, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899876.46317.ec
2022
Journal Article
Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility
Ayfan, Abdulrahman K. S., Macdonald, Joanne, Irwin, Adam D., Zowawi, Hosam M., Forde, Brian M., Paterson, David L., Lahra, Monica M. and Whiley, David M. (2022). Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility. Journal of Antimicrobial Chemotherapy, 77 (11), 2933-2936. doi: 10.1093/jac/dkac242
2022
Journal Article
Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia
Blythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6
2022
Journal Article
An innovative Antimicrobial Stewardship Program for children in remote and regional areas in Queensland, Australia: optimizing antibiotic use through timely intravenous-to-oral conversion
Avent, M.L., Lee, X.J., Irwin, A.D., Graham, N., Brain, D., Fejzic, J., van Driel, M. and Clark, J.E. (2022). An innovative Antimicrobial Stewardship Program for children in remote and regional areas in Queensland, Australia: optimizing antibiotic use through timely intravenous-to-oral conversion. Journal of Global Antimicrobial Resistance, 28, 53-58. doi: 10.1016/j.jgar.2021.11.014
2022
Journal Article
Neonatal vascular access practice and complications : An observational study of 1,375 catheter days
McIntyre, Colette, August, Deanne, Cobbald, Linda, Lack, Gill, Takashima, Mari, Foxcroft, Katie, Marsh, Nicole, Smith, Patricia, New, Karen, Koorts, Pieter, Irwin, Adam and Ullman, Amanda (2022). Neonatal vascular access practice and complications : An observational study of 1,375 catheter days. Journal of Perinatal and Neonatal Nursing, 37 (4), 332-339. doi: 10.1097/jpn.0000000000000589
2022
Journal Article
Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study
Parker, Suzanne L., Irwin, Adam D., Hosking, Francine, August, Deanne, Schoenmaker, Brittany, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Davies, Mark W. (2022). Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study. International Journal of Antimicrobial Agents, 59 (2) 106513, 1-2. doi: 10.1016/j.ijantimicag.2021.106513
2021
Journal Article
Treatment of cutaneous leishmaniasis in a nonendemic country: a case series of children in Australia
Hill, Nicholas, Irwin, Adam, Graham, Nicolette, Leung, Clare, Francis, Joshua R., Wall, Nerilee and Nourse, Clare (2021). Treatment of cutaneous leishmaniasis in a nonendemic country: a case series of children in Australia. The Pediatric Infectious Disease Journal, 41 (4), e177-e181. doi: 10.1097/inf.0000000000003445
2021
Journal Article
The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions
Schults, Jessica, Charles, Karina, Long, Debbie, Brown, Georgia, Copnell, Beverley, Dargaville, Peter, Davies, Kylie, Erikson, Simon, Forrest, Kate, Harnischfeger, Jane, Irwin, Adam, Kendrik, Tina, Lake, Anna, Ntoumenopoulos, George, Waak, Michaela, Woodard, Mark, Tume, Lyvonne, Cooke, Marie, Mitchell, Marion, Hall, Lisa and Ullman, Amanda (2021). The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions. Australian Critical Care, 35 (6), 651-660. doi: 10.1016/j.aucc.2021.10.005
2021
Journal Article
Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program
Raman, Sainath, English, Alana, O'Keefe, Meagan, Harley, Amanda, Steele, Mary, Minogue, Jess, Weller, Kate, Long, Debbie, Irwin, Adam and Lister, Paula (2021). Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program. Frontiers in Pediatrics, 9 759234, 759234. doi: 10.3389/fped.2021.759234
2021
Journal Article
Pediatric antifungal prescribing patterns identify significant opportunities to rationalize antifungal use in children
Ferreras-Antolín, Laura, Irwin, Adam, Atra, Ayad, Chapelle, Faye, Drysdale, Simon B., Emonts, Marieke, McMaster, Paddy, Paulus, Stephane, Patel, Sanjay, Rompola, Menie, Vergnano, Stefania, Whittaker, Elizabeth and Warris, Adilia (2021). Pediatric antifungal prescribing patterns identify significant opportunities to rationalize antifungal use in children. The Pediatric Infectious Disease Journal, 41 (3), e69-e74. doi: 10.1097/INF.0000000000003402
2021
Conference Publication
Recommendations for endotracheal suction interventions in children with highly infectious respiratory disease: results from a RAND/UCLA binational appropriateness panel
Schults, Jessica, Charles, Karina, Long, Debbie, Erikson, Simon, Irwin, Adam, Waak, Michaela, Hall, Lisa and Ullman, Amanda (2021). Recommendations for endotracheal suction interventions in children with highly infectious respiratory disease: results from a RAND/UCLA binational appropriateness panel. 9th International Australasian College for Infection Prevention and Control (ACIPC) online conference, Online, 7-10 November 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.idh.2021.09.031
2021
Journal Article
Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department
Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573
2021
Journal Article
Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study
Venkatesh, Balasubramanian, Schlapbach, Luregn, Mason, Donna, Wilks, Kathryn, Seaton, Robert, Lister, Paula, Irwin, Adam, Lane, Paul, Redpath, Lyndell, Gibbons, Kristen, Ergetu, Endrias and Rice, Michael (2021). Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study. The Lancet Regional Health - Western Pacific, 18 100305, 100305. doi: 10.1016/j.lanwpc.2021.100305
2021
Journal Article
Paediatric Active Enhanced Disease Surveillance (PAEDS) 2019: Prospective hospital-based surveillance for serious paediatric conditions
Dinsmore, Nicole, McRae, Jocelynne E., Quinn, Helen E., Glover, Catherine, Dougherty, Sonia, McMinn, Allissa, Crawford, Nigel, Marshall, Helen, Carlson, Samantha J, Blyth, Christopher, Lucas, Ryan, Irwin, Adam, Macartney, Kristine, Britton, Philip N, Wood, Nicholas and The Paediatric Active Enhanced Disease Surveillance network (2021). Paediatric Active Enhanced Disease Surveillance (PAEDS) 2019: Prospective hospital-based surveillance for serious paediatric conditions. Communicable Diseases Intelligence, 45, 1-24. doi: 10.33321/cdi.2021.45.53
2021
Journal Article
MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction
Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction. BMC Genomics, 22 (1) 474, 474. doi: 10.1186/s12864-021-07767-z
2021
Journal Article
Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)
Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680
2021
Journal Article
New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care
Peri, Anna Maria, Stewart, Adam, Hume, Anna, Irwin, Adam and Harris, Patrick N A (2021). New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care. Current Infectious Disease Reports, 23 (8) 12, 12. doi: 10.1007/s11908-021-00755-0
2021
Journal Article
Role of C reactive protein and procalcitonin in the diagnosis of lower respiratory tract infection in children in the outpatient setting
Pérez-López, Andrés, Irwin, Adam, Rodrigo, Carlos and Prat-Aymerich, Cristina (2021). Role of C reactive protein and procalcitonin in the diagnosis of lower respiratory tract infection in children in the outpatient setting. BMJ, 373 (11) n1409, n1409. doi: 10.1136/bmj.n1409
2021
Journal Article
Normal saline and lung recruitment with paediatric endotracheal suction (NARES): a pilot, factorial, randomised controlled trial
Schults, Jessica A., Cooke, Marie, Long, Debbie, Schibler, Andreas, Ware, Robert S., Charles, Karina, Irwin, Adam and Mitchell, Marion L. (2021). Normal saline and lung recruitment with paediatric endotracheal suction (NARES): a pilot, factorial, randomised controlled trial. Australian Critical Care, 34 (6), 530-538. doi: 10.1016/j.aucc.2021.01.006
2021
Journal Article
Rapid detection of NDM and VIM carbapenemase encoding genes by recombinase polymerase amplification and lateral flow–based detection
Ayfan, Abdulrahman K. S., Macdonald, Joanne, Harris, Patrick N. A., Heney, Claire, Paterson, David L., Trembizki, Ella, Wang, Claire Y. T., Whiley, David M., Zowawi, Hosam M. and Irwin, Adam D. (2021). Rapid detection of NDM and VIM carbapenemase encoding genes by recombinase polymerase amplification and lateral flow–based detection. European Journal of Clinical Microbiology & Infectious Diseases, 40 (11), 2447-2453. doi: 10.1007/s10096-021-04267-6
Funding
Current funding
Supervision
Availability
- Associate Professor Adam Irwin is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Gram-negative bloodstream infections in Australian children
Principal Advisor
Other advisors: Dr Geoff Spurling, Professor Colleen Lau, Mr Mark Chatfield
-
Doctor Philosophy
Accelerating pathogen detection and antibiotic resistance prediction in children with suspected sepsis.
Principal Advisor
Other advisors: Associate Professor David Whiley, Dr Patrick Harris
-
Doctor Philosophy
The Burden of Extrapulmonary Tuberculosis in Africa
Associate Advisor
Other advisors: Associate Professor David Harley, Professor Clare Nourse, Associate Professor Judith Dean
-
Doctor Philosophy
Extra-Pulmonary Tuberculosis in Africa - Prevalence, Associated Country-level Variables, and Assessment of Country TB Guidelines and National Strategic Plans
Associate Advisor
Other advisors: Associate Professor David Harley, Associate Professor Judith Dean, Professor Clare Nourse
-
Doctor Philosophy
Rapid detection of AMR targets using isothermal technology
Associate Advisor
Other advisors: Associate Professor David Whiley
-
Doctor Philosophy
New diagnostic strategies for antibiotic-resistant infections
Associate Advisor
Other advisors: Dr Patrick Harris
-
Doctor Philosophy
Rapid detection of AMR targets using isothermal technology
Associate Advisor
Other advisors: Associate Professor David Whiley
-
Doctor Philosophy
The development of an integrated molecular diagnostic pathway to optimise the treatment of cytomegalovirus in children undergoing haematopoietic stem cell transplant
Associate Advisor
Other advisors: Dr Kym Lowry, Associate Professor David Whiley, Dr Emma Sweeney
-
Doctor Philosophy
Expanding Data Sets to Allow Improved Critical Care for Children - Outpatient Risk Prediction
Associate Advisor
Other advisors: Professor Shazia Sadiq, Associate Professor Sen Wang
-
Doctor Philosophy
Rapid detection of AMR targets using isothermal technology.
Associate Advisor
Other advisors: Associate Professor David Whiley, Dr Leah Roberts
-
Doctor Philosophy
The development of an integrated molecular diagnostic pathway to optimise the treatment of cytomegalovirus in children undergoing haematopoietic stem cell transplant
Associate Advisor
Other advisors: Dr Kym Lowry, Associate Professor David Whiley, Dr Emma Sweeney
-
Doctor Philosophy
Extra-Pulmonary Tuberculosis in Africa - Prevalence, Associated Country-level Variables, and Assessment of Country TB Guidelines and National Strategic Plans
Associate Advisor
Other advisors: Associate Professor David Harley, Associate Professor Judith Dean, Professor Clare Nourse
-
Doctor Philosophy
Improving Sepsis Management through Better Data and Rapid Learning
Associate Advisor
Other advisors: Professor Andrew Burton-Jones, Associate Professor Ida Asadi Someh, Professor Marta Indulska
Media
Enquiries
Contact Associate Professor Adam Irwin directly for media enquiries about:
- Antimicrobial resistance
- Childhood infections
- Sepsis
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