Overview
Background
Dr Adam Irwin is a Principal Research Fellow in Paediatric Infectious Diseases at The University of Queensland and Queensland Children’s Hospital in Brisbane, Australia. His research focuses on the early recognition of invasive infections and sepsis, and the optimal use of antimicrobials in children. He is the medical co-chair of the Queensland Paediatric Sepsis Program which was awarded a Global Sepsis Alliance award in 2020, and Queensland Health Excellence awards in 2022 for Healthcare Delivery and Consumer Engagement, and a member of the Australian Group on Antimicrobial Resistance-Kids Steering Committee. He is a recipient of a National Health and Medical Research Council Emerging Leadership Fellowship to investigate the management of multi-drug resistant gram-negative infections in children.
Adam studied at the University of Birmingham Medical School and completed training in Paediatric Infectious Disease and Immunology in London. He was awarded his PhD by the University of Liverpool Institute of Infection and Global Health in 2016. Prior to relocating to Queensland, he was secretary of the British Paediatric Allergy, Immunity and Infection Group.
Availability
- Associate Professor Adam Irwin is:
- Available for supervision
- Media expert
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Birmingham
- Doctor of Philosophy, University of Liverpool
Works
Search Professor Adam Irwin’s works on UQ eSpace
2023
Journal Article
Application of the ViroKey® SQ FLEX assay for detection of cytomegalovirus antiviral resistance
Hume, Jocelyn, Lowry, Kym, Whiley, David M., Irwin, Adam D., Bletchly, Cheryl and Sweeney, Emma L. (2023). Application of the ViroKey® SQ FLEX assay for detection of cytomegalovirus antiviral resistance. Journal of Clinical Virology, 167 105556, 1-8. doi: 10.1016/j.jcv.2023.105556
2023
Journal Article
Cytomegalovirus in children undergoing haematopoietic stem cell transplantation: a diagnostic and therapeutic approach to antiviral resistance
Hume, Jocelyn, Sweeney, Emma L., Lowry, Kym, Fraser, Chris, Clark, Julia E., Whiley, David M. and Irwin, Adam D. (2023). Cytomegalovirus in children undergoing haematopoietic stem cell transplantation: a diagnostic and therapeutic approach to antiviral resistance. Frontiers in Pediatrics, 11 1180392, 1180392. doi: 10.3389/fped.2023.1180392
2023
Journal Article
A multicentre, retrospective audit of fosfomycin use for urinary tract infections in Australian children and adolescents
Purcell, Rachael, Yeoh, Daniel, Bowen, Asha, Britton, Philip N., Carr, Jeremy P., Chen, Ming, Cheung, Kaman, Clark, Julia, Irwin, Adam, Lai, Tony, Lorenzen, Ulrik, Steer, Andrew, Wen, Sophie, Williams, Phoebe, Yap, Natalie, Cooper, Celia and Gwee, Amanda (2023). A multicentre, retrospective audit of fosfomycin use for urinary tract infections in Australian children and adolescents. Journal of Antimicrobial Chemotherapy, 78 (7), 1-6. doi: 10.1093/jac/dkad131
2023
Journal Article
Rapid molecular detection of CMY-2, and CTX-M group 1 and 9 variants via recombinase polymerase amplification
Ertl, Nicole G., Irwin, Adam D., Macdonald, Joanne, Bauer, Michelle J., Wang, Claire Y. T., Harris, Patrick N. A., Heney, Claire, Zowawi, Hosam M. and Whiley, David M. (2023). Rapid molecular detection of CMY-2, and CTX-M group 1 and 9 variants via recombinase polymerase amplification. JAC - Antimicrobial Resistance, 5 (2) dlad023, dlad023. doi: 10.1093/jacamr/dlad023
2023
Journal Article
Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA
Davies, Mark R., Keller, Nadia, Brouwer, Stephan, Jespersen, Magnus G., Cork, Amanda J., Hayes, Andrew J., Pitt, Miranda E., De Oliveira, David M. P., Harbison-Price, Nichaela, Bertolla, Olivia M., Mediati, Daniel G., Curren, Bodie F., Taiaroa, George, Lacey, Jake A., Smith, Helen V., Fang, Ning-Xia, Coin, Lachlan J. M., Stevens, Kerrie, Tong, Steven Y. C., Sanderson-Smith, Martina, Tree, Jai J., Irwin, Adam D., Grimwood, Keith, Howden, Benjamin P., Jennison, Amy V. and Walker, Mark J. (2023). Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA. Nature Communications, 14 (1) 1051, 1-12. doi: 10.1038/s41467-023-36717-4
2023
Journal Article
Evolving insights into the epidemiology of Moraxella species bloodstream infection from two decades of surveillance in Queensland, Australia
Schults, Jessica, Edwards, Felicity, Charles, Karina, Irwin, Adam D., Rickard, Claire M., Harris, Patrick N. A., Paterson, David L. and Laupland, Kevin (2023). Evolving insights into the epidemiology of Moraxella species bloodstream infection from two decades of surveillance in Queensland, Australia. European Journal of Clinical Microbiology and Infectious Diseases, 42 (2), 209-216. doi: 10.1007/s10096-022-04540-2
2023
Journal Article
Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia
Gilholm, Patricia, Gibbons, Kristen, Lister, Paula, Harley, Amanda, Irwin, Adam, Raman, Sainath, Rice, Michael, Schlapbach, Luregn J. and Queensland Statewide Sepsis Collaborative (2023). Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia. BMJ Open, 13 (1) e061431, 1-25. doi: 10.1136/bmjopen-2022-061431
2023
Journal Article
Nystatin is commonly prescribed as prophylaxis in children beyond the neonatal age
Jayawardena-Thabrew, Harshani, Warris, Adilia, PASOAP Group , Irwin, Adam and Ferreras-Antolin, Laura (2023). Nystatin is commonly prescribed as prophylaxis in children beyond the neonatal age. Medical Mycology, 61 (1) myac097. doi: 10.1093/mmy/myac097
2022
Journal Article
Improving paediatric antimicrobial stewardship in remote and regional Queensland hospitals: development and qualitative evaluation of a tailored intervention for intravenous-to-oral antibiotic switching
Sharman, Leah S., Avent, Minyon L., Lyall, Vivian, Fejzic, Jasmina, Clark, Julia E., Irwin, Adam, Graham, Nicolette and van Driel, Mieke L. (2022). Improving paediatric antimicrobial stewardship in remote and regional Queensland hospitals: development and qualitative evaluation of a tailored intervention for intravenous-to-oral antibiotic switching. BMJ Open, 12 (12) e064888, 1-10. doi: 10.1136/bmjopen-2022-064888
2022
Conference Publication
Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department
Gilholm, P., Irwin, A., Lister, P., Harley, A., Raman, S., Schlapbach, L. J. and Gibbons, K. (2022). Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department. 11th Congress of the World Federation of Pediatric Intensive & Critical Care Societies, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899876.46317.ec
2022
Journal Article
Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility
Ayfan, Abdulrahman K. S., Macdonald, Joanne, Irwin, Adam D., Zowawi, Hosam M., Forde, Brian M., Paterson, David L., Lahra, Monica M. and Whiley, David M. (2022). Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility. Journal of Antimicrobial Chemotherapy, 77 (11), 2933-2936. doi: 10.1093/jac/dkac242
2022
Journal Article
Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia
Blythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6
2022
Journal Article
An innovative Antimicrobial Stewardship Program for children in remote and regional areas in Queensland, Australia: optimizing antibiotic use through timely intravenous-to-oral conversion
Avent, M.L., Lee, X.J., Irwin, A.D., Graham, N., Brain, D., Fejzic, J., van Driel, M. and Clark, J.E. (2022). An innovative Antimicrobial Stewardship Program for children in remote and regional areas in Queensland, Australia: optimizing antibiotic use through timely intravenous-to-oral conversion. Journal of Global Antimicrobial Resistance, 28, 53-58. doi: 10.1016/j.jgar.2021.11.014
2022
Journal Article
Neonatal vascular access practice and complications : An observational study of 1,375 catheter days
McIntyre, Colette, August, Deanne, Cobbald, Linda, Lack, Gill, Takashima, Mari, Foxcroft, Katie, Marsh, Nicole, Smith, Patricia, New, Karen, Koorts, Pieter, Irwin, Adam and Ullman, Amanda (2022). Neonatal vascular access practice and complications : An observational study of 1,375 catheter days. Journal of Perinatal and Neonatal Nursing, 37 (4), 332-339. doi: 10.1097/jpn.0000000000000589
2022
Journal Article
Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study
Parker, Suzanne L., Irwin, Adam D., Hosking, Francine, August, Deanne, Schoenmaker, Brittany, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Davies, Mark W. (2022). Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study. International Journal of Antimicrobial Agents, 59 (2) 106513, 1-2. doi: 10.1016/j.ijantimicag.2021.106513
2021
Journal Article
Treatment of cutaneous leishmaniasis in a nonendemic country: a case series of children in Australia
Hill, Nicholas, Irwin, Adam, Graham, Nicolette, Leung, Clare, Francis, Joshua R, Wall, Nerilee and Nourse, Clare (2021). Treatment of cutaneous leishmaniasis in a nonendemic country: a case series of children in Australia. The Pediatric Infectious Disease Journal, Publish Ahead of Print (4), e177-e181. doi: 10.1097/inf.0000000000003445
2021
Journal Article
The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions
Schults, Jessica, Charles, Karina, Long, Debbie, Brown, Georgia, Copnell, Beverley, Dargaville, Peter, Davies, Kylie, Erikson, Simon, Forrest, Kate, Harnischfeger, Jane, Irwin, Adam, Kendrik, Tina, Lake, Anna, Ntoumenopoulos, George, Waak, Michaela, Woodard, Mark, Tume, Lyvonne, Cooke, Marie, Mitchell, Marion, Hall, Lisa and Ullman, Amanda (2021). The Paediatric AirWay Suction (PAWS) appropriateness guide for endotracheal suction interventions. Australian Critical Care, 35 (6), 651-660. doi: 10.1016/j.aucc.2021.10.005
2021
Journal Article
Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program
Raman, Sainath, English, Alana, O'Keefe, Meagan, Harley, Amanda, Steele, Mary, Minogue, Jess, Weller, Kate, Long, Debbie, Irwin, Adam and Lister, Paula (2021). Designing support structures post sepsis in children: perspectives of the Queensland Paediatric Sepsis Program. Frontiers in Pediatrics, 9 759234, 759234. doi: 10.3389/fped.2021.759234
2021
Journal Article
Pediatric antifungal prescribing patterns identify significant opportunities to rationalize antifungal use in children
Ferreras-Antolín, Laura, Irwin, Adam, Atra, Ayad, Chapelle, Faye, Drysdale, Simon B., Emonts, Marieke, McMaster, Paddy, Paulus, Stephane, Patel, Sanjay, Rompola, Menie, Vergnano, Stefania, Whittaker, Elizabeth and Warris, Adilia (2021). Pediatric antifungal prescribing patterns identify significant opportunities to rationalize antifungal use in children. The Pediatric Infectious Disease Journal, Publish Ahead of Print (3), e69-e74. doi: 10.1097/INF.0000000000003402
2021
Conference Publication
Recommendations for endotracheal suction interventions in children with highly infectious respiratory disease: results from a RAND/UCLA binational appropriateness panel
Schults, Jessica, Charles, Karina, Long, Debbie, Erikson, Simon, Irwin, Adam, Waak, Michaela, Hall, Lisa and Ullman, Amanda (2021). Recommendations for endotracheal suction interventions in children with highly infectious respiratory disease: results from a RAND/UCLA binational appropriateness panel. 9th International Australasian College for Infection Prevention and Control (ACIPC) online conference, Online, 7-10 November 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.idh.2021.09.031
Funding
Current funding
Supervision
Availability
- Associate Professor Adam Irwin is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Gram-negative bloodstream infections in Australian children
Principal Advisor
Other advisors: Dr Geoff Spurling, Professor Colleen Lau, Mr Mark Chatfield
-
Doctor Philosophy
Accelerating pathogen detection and antibiotic resistance prediction in children with suspected sepsis.
Principal Advisor
Other advisors: Dr Patrick Harris
-
Doctor Philosophy
Rapid detection of AMR targets using isothermal technology
Associate Advisor
Other advisors: Associate Professor David Whiley
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Doctor Philosophy
Expanding Data Sets to Allow Improved Critical Care for Children - Outpatient Risk Prediction
Associate Advisor
Other advisors: Professor Shazia Sadiq, Associate Professor Sen Wang
-
Doctor Philosophy
The development of an integrated molecular diagnostic pathway to optimise the treatment of cytomegalovirus in children undergoing haematopoietic stem cell transplant
Associate Advisor
Other advisors: Dr Kym Lowry, Associate Professor David Whiley, Dr Emma Sweeney
-
Doctor Philosophy
Improving Sepsis Management through Better Data and Rapid Learning
Associate Advisor
Other advisors: Professor Andrew Burton-Jones, Dr Ida Asadi Someh, Professor Marta Indulska
-
Doctor Philosophy
The Burden of Extrapulmonary Tuberculosis in Africa
Associate Advisor
Other advisors: Associate Professor David Harley, Professor Clare Nourse, Associate Professor Judith Dean
Media
Enquiries
Contact Associate Professor Adam Irwin directly for media enquiries about:
- Antimicrobial resistance
- Childhood infections
- Sepsis
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