Professor Marc Ruitenberg
Professor

Marc Ruitenberg

Email: 
Phone: 
+61 7 334 67602

Availability

Professor Marc Ruitenberg is:
Available for supervision
Media expert

Fields of research

Biological Sciences Clinical sciences Neurosciences

Qualifications

  • Doctor of Philosophy, Vrije Universiteit Amsterdam

Search Professor Marc Ruitenberg’s works on UQ eSpace

110 works between 1999 and 2024
All (110) Journal Article (85) Book Chapter (3) Conference Publication (21) Other Outputs (1)

41 - 60 of 110 works

2017

Journal Article

The alternative receptor for complement component 5a, C5aR2, conveys neuroprotection in traumatic spinal cord injury

Biggins, Patrick, Brennan, Faith, Taylor, Stephen, Woodruff, Trent and Ruitenberg, Marc (2017). The alternative receptor for complement component 5a, C5aR2, conveys neuroprotection in traumatic spinal cord injury. Journal of Neurotrauma, 34 (12), 2075-2085. doi: 10.1089/neu.2016.4701

The alternative receptor for complement component 5a, C5aR2, conveys neuroprotection in traumatic spinal cord injury

Featured

2017

Journal Article

Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

Lee, John D., Kumar, Vinod, Fung, Jenny N. T., Ruitenberg, Marc J., Noakes, Peter G. and Woodruff, Trent M. (2017). Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. British Journal of Pharmacology, 173 (8), 689-699. doi: 10.1111/bph.13730

Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

2017

Journal Article

Disease-modifying effect of intravenous immunoglobulin in an experimental model of epilepsy

Chen, Min, Arumugam, Thiruma V., Leanage, Gayeshika, Tieng, Quang M., Yadav, Ashwin, Ullmann, Jeremy F. P., She, David T., Truong, Vy, Ruitenberg, Marc J. and Reutens, David C. (2017). Disease-modifying effect of intravenous immunoglobulin in an experimental model of epilepsy. Scientific Reports, 7 (1) 40528, 40528. doi: 10.1038/srep40528

Disease-modifying effect of intravenous immunoglobulin in an experimental model of epilepsy

2017

Journal Article

It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function

Jung, Won-Cheol, Levesque, Jean-Pierre and Ruitenberg, Marc J. (2017). It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function. Seminars in Cell and Developmental Biology, 61, 60-70. doi: 10.1016/j.semcdb.2016.08.010

It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function

2016

Journal Article

An atypical role for the myeloid receptor Mincle in central nervous system injury

Arumugam, Thiruma V., Manzanero, Silvia, Furtado, Milena, Biggins, Patrick J., Hsieh, Yu Hsuan, Gelderblom, Mathias, MacDonald, Kelli P. A., Salimova, Ekaterina, Li, Yu I., Korn, Othmar, Dewar, Deborah, Macrae, I. Mhairi, Ashman, Robert B., Tang, Sung-Chun, Rosenthal, Nadia A., Ruitenberg, Marc J., Magnus, Tim and Wells, Christine A. (2016). An atypical role for the myeloid receptor Mincle in central nervous system injury. Journal of Cerebral Blood Flow and Metabolism, 37 (6), 2098-2111. doi: 10.1177/0271678X16661201

An atypical role for the myeloid receptor Mincle in central nervous system injury

2016

Journal Article

A case of mistaken identity: CD11c-eYFP+ cells in the normal mouse brain parenchyma and neural retina display the phenotype of microglia, not dendritic cells

Dando, Samantha J., Naranjo Golborne, Cecilia, Chinnery, Holly R., Ruitenberg, Marc J. and McMenamin, Paul G. (2016). A case of mistaken identity: CD11c-eYFP+ cells in the normal mouse brain parenchyma and neural retina display the phenotype of microglia, not dendritic cells. Glia, 64 (8), 1331-1349. doi: 10.1002/glia.23005

A case of mistaken identity: CD11c-eYFP+ cells in the normal mouse brain parenchyma and neural retina display the phenotype of microglia, not dendritic cells

2016

Journal Article

IVIg attenuates complement and improves spinal cord injury outcomes in mice

Brennan, Faith H., Kurniawan, Nyoman D., Vukovic, Jana, Bartlett, Perry F., Käsermann, Fabian, Arumugam, Thiruman V., Basta, Milan and Ruitenberg, Marc J. (2016). IVIg attenuates complement and improves spinal cord injury outcomes in mice. Annals of Clinical and Translational Neurology, 3 (7), 495-511. doi: 10.1002/acn3.318

IVIg attenuates complement and improves spinal cord injury outcomes in mice

2016

Conference Publication

Immune privilege in the central nervous system revisited: are there dendritic cells in the brain?

Dando, S., Chinnery, H., Ruitenberg, M. and McMenamin, P. (2016). Immune privilege in the central nervous system revisited: are there dendritic cells in the brain?. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August, 2016. Weinheim, Germany: Wiley.

Immune privilege in the central nervous system revisited: are there dendritic cells in the brain?

2016

Journal Article

Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions

Brennan, Faith H., Lee, John D., Ruitenberg, Marc J. and Woodruff, Trent M. (2016). Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions. Seminars in Immunology, 28 (3), 292-308. doi: 10.1016/j.smim.2016.03.015

Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions

2016

Conference Publication

Investigating the role of complement component C5a receptor 2 (C5aR2/C5L2) in spinal cord injury

Biggins, P. J. C., Brennan, F. H., Taylor, S. M., Woodruff, T. M. and Ruitenberg, M. J. (2016). Investigating the role of complement component C5a receptor 2 (C5aR2/C5L2) in spinal cord injury. The XXVI International Complement Workshop (ICW), Kanazawa, Japan, 4-8 September 2016. Muenchen, Germany: Elsevier. doi: 10.1016/j.imbio.2016.06.058

Investigating the role of complement component C5a receptor 2 (C5aR2/C5L2) in spinal cord injury

2016

Conference Publication

The rd8 mutation in the Crumbs1 gene upregulates activation markers on retinal and brain microglia and CD11c-eYFP(+) cells

Dando, Samantha, Naranjo-Golborne, Cecilia, Chinnery, Holly, Ruitenberg, Marc and McMenamin, Paul G. (2016). The rd8 mutation in the Crumbs1 gene upregulates activation markers on retinal and brain microglia and CD11c-eYFP(+) cells. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Seattle, WA USA, May 01-05, 2016. Rockville, MD USA: Association for Research in Vision and Ophthalmology.

The rd8 mutation in the Crumbs1 gene upregulates activation markers on retinal and brain microglia and CD11c-eYFP(+) cells

2016

Conference Publication

Dynamics of inflammatory immune response in a mouse model of traumatic spinal cord injury, potential therapeutic targets

Golakani, Hassanpour M., Mohammad, M., Li, H., Saxena, M., Breit, S., Ruitenberg, M. and Brown, D. (2016). Dynamics of inflammatory immune response in a mouse model of traumatic spinal cord injury, potential therapeutic targets. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. Germany: Wiley.

Dynamics of inflammatory immune response in a mouse model of traumatic spinal cord injury, potential therapeutic targets

2015

Journal Article

Targeting acute inflammation to complement spinal cord repair

Brennan, Faith H. and Ruitenberg, Marc J. (2015). Targeting acute inflammation to complement spinal cord repair. Neural Regeneration Research, 10 (10), 1596-1598. doi: 10.4103/1673-5374.165268

Targeting acute inflammation to complement spinal cord repair

2015

Journal Article

The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injury

Brennan, Faith H., Gordon, Richard, Lao, Hong W., Biggins, Patrick J., Taylor, Stephen M., Franklin, Robin J. M., Woodruff, Trent M. and Ruitenberg, Marc J. (2015). The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injury. Journal of Neuroscience, 35 (16), 6517-6531. doi: 10.1523/JNEUROSCI.5218-14.2015

The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injury

2015

Conference Publication

Characterization of YFP plus cells in the retina of CD11c-eYFP transgenic mice: the effects of breeding out the Crb1(rd8) mutation

Dando, Samantha, Chen, Xiangting, Ruitenberg, Marc and McMenamin, Paul G. (2015). Characterization of YFP plus cells in the retina of CD11c-eYFP transgenic mice: the effects of breeding out the Crb1(rd8) mutation. Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), Denver, CO United States, May 3-7, 2015. Rockville, MD United States: Association for Research in Vision and Ophthalmology.

Characterization of YFP plus cells in the retina of CD11c-eYFP transgenic mice: the effects of breeding out the Crb1(rd8) mutation

2014

Journal Article

PI3K delta inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model

Low, Pei Ching, Manzanero, Silvia, Mohannak, Nika, Narayana, Vinod K., Nguyen, Tam H., Kvaskoff, David, Brennan, Faith H., Ruitenberg, Marc J., Gelderblom, Mathias, Magnus, Tim, Kim, Hyun Ah, Broughton, Brad R. S., Sobey, Christopher G., Vanhaesebroeck, Bart, Stow, Jennifer L., Arumugam, Thiruma V. and Meunier, Frédéric A. (2014). PI3K delta inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model. Nature Communications, 5 (3450) 3450, 1-12. doi: 10.1038/ncomms4450

PI3K delta inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model

2014

Journal Article

Immune cell trafficking from the brain maintains CNS immune tolerance

Mohammad, Mohammad G., Tsai, Vicky W.W., Ruitenberg, Marc J., Hassanpour, Masoud, Li, Hui, Hart, Prue H., Breit, Samuel N., Sawchenko, Paul E. and Brown, David A. (2014). Immune cell trafficking from the brain maintains CNS immune tolerance. Journal of Clinical Investigation, 124 (3), 1228-1241. doi: 10.1172/JCI71544

Immune cell trafficking from the brain maintains CNS immune tolerance

2014

Conference Publication

Acute Antagonism of the Complement Anaphylatoxin Receptor C5Ar Improves the Outcome From Experimental Spinal Cord Injury

Ruitenberg, Marc J., Brennan, Faith H., Gordon, Richard, Blomster, Linda V., Lao, Hong Wa, Cowin, Gary J., Taylor, Stephen M. and Woodruff, Trent M. (2014). Acute Antagonism of the Complement Anaphylatoxin Receptor C5Ar Improves the Outcome From Experimental Spinal Cord Injury. 11th Symposium of the International-Neurotrauma-Society, Budapest, Hungary, 19-23 March 2014. New Rochelle, NY United States: Mary Ann Liebert.

Acute Antagonism of the Complement Anaphylatoxin Receptor C5Ar Improves the Outcome From Experimental Spinal Cord Injury

2014

Conference Publication

PI3K delta inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model

Low, Pei Ching (Regine), Manzanero, Silvia, Narayana, Vinod K., Nguyen, Tam H., Kvaskoff, David, Brennan, Faith H., Ruitenberg, Marc J., Gelderblom, Mathias, Magnus, Tim, Kim, Hyun Ah, Broughton, Brad R. S., Sobey, Christopher G., Vanhaesebroeck, Bart, Stow, Jennifer L., Arumugam, Thiruma V. and Meunier, Frederic A. (2014). PI3K delta inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne, Australia, 26-29 October 2014. London, United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.126

PI3K delta inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model

2014

Conference Publication

CNS DCs modulate peripheral anti-CNS immunity

Mohammad, Mohammad, Tsai, Vicky Wang Wei, Ruitenberg, Marc, Hassanpour, Masoud, Li, Hui, Hart, Prue, Breit, Samuel, Sawchenko, Paul and Brown, David (2014). CNS DCs modulate peripheral anti-CNS immunity. 12th International Congress of Neuroimmunology (ISNI), Mainz Germany, 9-13 November, 2014. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.jneuroim.2014.08.218

CNS DCs modulate peripheral anti-CNS immunity

Current funding

  • 2024 - 2026
    Development of a clinical hands-on score for predicting infections after acute SCI based on clinical information from admission to intensive / surgical care (Wings for Life administered by CUB)
    Charite - Universitätsmedizin Berlin
    Open grant
  • 2022 - 2025
    Development of live cell assay for the detection of anti-neuronal antibodies
    Metro South Hospital and Health Service
    Open grant
  • 2017 - 2025
    Spinal injury research
    Spinal Cure Australia
    Open grant

Past funding

  • 2021 - 2024
    Dissecting Inflammation and spinal cord lesion site development at single-cell resolution
    Wings for Life Project Grant
    Open grant
  • 2021 - 2024
    Identification of therapy-resistant cells driving relapse in Medulloblastoma from integrated spatial transcriptomics and tissue imaging
    NHMRC IDEAS Grants
    Open grant
  • 2019 - 2020
    Blocking ROCK2 to improve recovery from brain injury
    Brain Foundation Research Gift
    Open grant
  • 2019 - 2022
    Furthering understanding of autoimmune encephalitis through clinical and immunobiological correlation
    Metro South Hospital and Health Service
    Open grant
  • 2019
    Advanced Brightfield and Fluorescent High Speed and Throughput Slide Scanner for biological, medical, materials science, and agricultural applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019
    Dissolution DNP Hyperpolariser
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2019
    In vivo imaging system for tracking inflammation, infection, cancer, pain and bioactive molecules
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2022
    Understanding the mechanism of action for intravenous immunoglobulin (IVIG) therapy in spinal cord injury
    NHMRC Project Grant
    Open grant
  • 2018 - 2022
    Repairing the chronically injured spinal cord with induced pluripotent stem cell (iPSC)-derived propriospinal interneuron transplants
    Perry Cross Spinal Research Foundation Limited
    Open grant
  • 2018 - 2019
    The contribution of extracellular vesicles to the outcome from SCI
    University of Oxford
    Open grant
  • 2016 - 2020
    Intravenous immunoglobulin therapy for acute spinal cord injury
    CSL Behring
    Open grant
  • 2016 - 2018
    Why macrophages promote heterotopic ossifications following spinal cord injuries
    NHMRC Project Grant
    Open grant
  • 2015
    A state-of-the-art spinning disc confocal microscope for high speed imaging of live cells and super resolution microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2020
    Determining the contribution of peripheral immune complement signalling in the progression of motor neuron disease
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Intravenous immunoglobulin (IVIG) therapy to improve recovery from spinal cord injury
    Wings for Life
    Open grant
  • 2014 - 2016
    Central nervous system dendritic cells - guilty or not guilty? (NHMRC Project Grant administered by Monash University)
    Monash University
    Open grant
  • 2014
    Innate immune complement signalling in peripheral immune cells during the progression of motor neurone disease
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2014 - 2017
    Targeting the complement activation fragment C5a to improve the outcome from spinal cord injury
    NHMRC Project Grant
    Open grant
  • 2013
    Spinning disk confocal for advanced high-speed histocytometry and neuromorphology analysis
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2015
    Spinal Cure CDF Co-funded Partnership: Unravelling heterogeneity and function of blood-borne macrophages in spinal cord injury in relation to their monocyte precursor origins
    Spinal Cure Australia
    Open grant
  • 2012
    Unravelling the role of blood-borne macrophages in the pathology associated with spinal cord injury (SCI)
    UQ Early Career Researcher
    Open grant
  • 2011
    Building UQ's analytical capacity in biomedical sciences
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    Molecular Stereology Facility Upgrade
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2011
    Enabling grant support - Marc Ruitenberg
    UQ External Support Enabling Grant
    Open grant
  • 2010
    Establishment of a digital Scanscope system for virtual microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2009 - 2010
    Ageing of the nasal neuroepithelium: macrophages the major culprit?
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2009
    CX3C chemokine signalling in the olfactory epithelium and its role in the self regulation of the olfactory system
    ARC Discovery Projects
    Open grant

Availability

Professor Marc Ruitenberg is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

Contact Professor Marc Ruitenberg directly for media enquiries about:

  • Neuroimmunology
  • Neuroinflammation
  • Spinal cord injury
  • Traumatic brain injury

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