Professor Paul Young
Professor

Paul Young

Email: 
Phone: 
+61 7 336 59044

Background

Molecular virology.

My group's research interests encompass the molecular biology and immunopathology of medically important viral infections including Ebola. Current studies are focussed on two different viruses; dengue virus, a serious mosquito-borne disease in many tropical countries, and Respiratory Syncytial Virus (RSV), a major cause of hospitalization of children with respiratory infections.

The primary goals of our research are the development of vaccine and anti-viral strategies for the control of infections as well as a clearer understanding of the pathogenesis of severe disease.

Current projects in my laboratory include:

  • Structural biology based studies on the dengue virus proteins, NS3 (the viral protease) and E (a virion surface protein involved in cell binding and entry) and the RSV protein F (the viral fusion protein) as targets for antiviral drug design
  • Sub-unit and DNA based vaccines for the dengue viruses
  • Molecular pathogenesis of severe dengue disease (in particular, the consequences of dengue virus infection of host macrophages and the induction of mediators of vascular leak)
  • Design and delivery of ribozymes (catalytic RNAs) to the respiratory tract as an antiviral strategy for RSV infections

These projects involve the application of a range of techniques covering a number of disciplines including molecular biology, immunology, biotechnology, molecular cell biology, protein biochemistry and structural biology.

Availability

Professor Paul Young is:
Available for supervision

Fields of research

Medical microbiology Microbiology

Qualifications

  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy of Virology, London School of Hygiene & Tropical Medicine

Search Professor Paul Young’s works on UQ eSpace

301 works between 1978 and 2024
All (301) Journal Article (197) Book Chapter (9) Conference Publication (95)

1 - 20 of 301 works

2024

Journal Article

Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein

McMillan, Christopher L. D., Wijesundara, Danushka K., Choo, Jovin J. Y., Amarilla, Alberto A., Modhiran, Naphak, Fernando, Germain J. P., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R. and Muller, David A. (2024). Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein. Journal of General Virology, 105 (1) ARTN 001947, 1-6. doi: 10.1099/jgv.0.001947

Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein

2023

Journal Article

Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine

Wijesundara, Danushka K., Yeow, Arthur, McMillan, Christopher L. D., Choo, Jovin J. Y., Todorovic, Aleksandra, Mekonnen, Zelalem A., Masavuli, Makutiro G., Young, Paul R., Gowans, Eric J., Grubor-Bauk, Branka and Muller, David A. (2023). Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine. Molecular Therapy Nucleic Acids, 34 102056. doi: 10.1016/j.omtn.2023.102056

Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine

2023

Journal Article

The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant

Pegg, Cassandra L., Modhiran, Naphak, Parry, Rhys H., Liang, Benjamin, Amarilla, Alberto A., Khromykh, Alexander A., Burr, Lucy, Young, Paul R., Chappell, Keith, Schulz, Benjamin L. and Watterson, Daniel (2023). The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant. Glycobiology, 34 (2) cwad097, 1-13. doi: 10.1093/glycob/cwad097

The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant

2023

Journal Article

Safety, tolerability, and immunogenicity of measles and rubella vaccine delivered with a high-density microarray patch: results from a randomized, partially double-blinded, placebo-controlled phase I clinical trial

Baker, Ben, Bermingham, Imogen M., Leelasena, Indika, Hickling, Julian, Young, Paul R., Muller, David A. and Forster, Angus H. (2023). Safety, tolerability, and immunogenicity of measles and rubella vaccine delivered with a high-density microarray patch: results from a randomized, partially double-blinded, placebo-controlled phase I clinical trial. Vaccines, 11 (11) 1725, 1-17. doi: 10.3390/vaccines11111725

Safety, tolerability, and immunogenicity of measles and rubella vaccine delivered with a high-density microarray patch: results from a randomized, partially double-blinded, placebo-controlled phase I clinical trial

2023

Journal Article

Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial

Chappell, Keith J., Mordant, Francesca L., Amarilla, Alberto A., Modhiran, Naphak, Liang, Benjamin, Li, Zheyi, Wijesundara, Danushka K., Lackenby, Julia A., Griffin, Paul, Bennet, Jillian K., Hensen, Luca, Zhang, Wuji, Nguyen, Thi H.O., Tran, Mai H., Tapley, Peter, Barnes, James, Reading, Patrick C., Kedzierska, Katherine, Ranasinghe, Charani, Subbarao, Kanta, Watterson, Daniel, Young, Paul R. and Munro, Trent P. (2023). Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial. eBioMedicine, 97 104842. doi: 10.1016/j.ebiom.2023.104842

Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial

2023

Journal Article

Microarray patches: scratching the surface of vaccine delivery

Choo, Jovin J. Y., McMillan, Christopher L. D., Young, Paul R. and Muller, David A. (2023). Microarray patches: scratching the surface of vaccine delivery. Expert Review of Vaccines, 22 (1), 937-955. doi: 10.1080/14760584.2023.2270598

Microarray patches: scratching the surface of vaccine delivery

2023

Journal Article

A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants

Modhiran, Naphak, Lauer, Simon Malte, Amarilla, Alberto A., Hewins, Peter, Lopes van den Broek, Sara Irene, Low, Yu Shang, Thakur, Nazia, Liang, Benjamin, Nieto, Guillermo Valenzuela, Jung, James, Paramitha, Devina, Isaacs, Ariel, Sng, Julian D. J., Song, David, Jørgensen, Jesper Tranekjær, Cheuquemilla, Yorka, Bürger, Jörg, Andersen, Ida Vang, Himelreichs, Johanna, Jara, Ronald, MacLoughlin, Ronan, Miranda-Chacon, Zaray, Chana-Cuevas, Pedro, Kramer, Vasko, Spahn, Christian M. T., Mielke, Thorsten, Khromykh, Alexander A., Munro, Trent, Jones, Martina L. ... Watterson, Daniel (2023). A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants. iScience, 26 (7) 107085, 107085. doi: 10.1016/j.isci.2023.107085

A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants

2023

Journal Article

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. mBio, 14 (3), e0081523. doi: 10.1128/mbio.00815-23

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

2023

Journal Article

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. mSphere, 8 (3), e0016523. doi: 10.1128/msphere.00165-23

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

2023

Journal Article

Save the microbes to save the planet. A call to action of the International Union of the Microbiological Societies (IUMS)

Rappuoli, Rino, Young, Paul, Ron, Eliora, Pecetta, Simone and Pizza, Mariagrazia (2023). Save the microbes to save the planet. A call to action of the International Union of the Microbiological Societies (IUMS). One Health Outlook, 5 (1) 5, 5. doi: 10.1186/s42522-023-00077-2

Save the microbes to save the planet. A call to action of the International Union of the Microbiological Societies (IUMS)

2023

Journal Article

Erratum: Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions (Proc. Natl. Acad. Sci. U.S.A. (2022) 119 (e2122680119) DOI: 10.1073/pnas.2122680119)

Blyton, Michaela D. J., Young, Paul R., Moore, Ben D. and Chappell, Keith J. (2023). Erratum: Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions (Proc. Natl. Acad. Sci. U.S.A. (2022) 119 (e2122680119) DOI: 10.1073/pnas.2122680119). Proceedings of the National Academy of Sciences of the United States of America, 120 (1) e2220541120. doi: 10.1073/pnas.2220541120

Erratum: Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions (Proc. Natl. Acad. Sci. U.S.A. (2022) 119 (e2122680119) DOI: 10.1073/pnas.2122680119)

2023

Journal Article

Statement in Support of: “Virology under the Microscope-a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope-a Call for Rational Discourse”. Journal of Virology, 97 (5). doi: 10.1128/jvi.00451-23

Statement in Support of: “Virology under the Microscope-a Call for Rational Discourse”

2023

Journal Article

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J. ... Woodruff, Trent M. (2023). SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein. Molecular Psychiatry, 28 (7), 2878-2893. doi: 10.1038/s41380-022-01831-0

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

2023

Book Chapter

Arbovirus Infections

Young, Paul R. (2023). Arbovirus Infections. Manson's tropical diseases. (pp. 172-201) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-7020-7959-7.00020-8

Arbovirus Infections

2022

Journal Article

Diversity and transmission of koala retrovirus: a case study in three captive koala populations

Joyce, Briony A., Blyton, Michaela D. J., Johnston, Stephen D., Meikle, William D., Vinette Herrin, Kimberly, Madden, Claire, Young, Paul R. and Chappell, Keith J. (2022). Diversity and transmission of koala retrovirus: a case study in three captive koala populations. Scientific Reports, 12 (1) 15787, 1-8. doi: 10.1038/s41598-022-18939-6

Diversity and transmission of koala retrovirus: a case study in three captive koala populations

2022

Journal Article

Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine

O’Donnell, Jake S., Isaacs, Ariel, Jakob, Virginie, Lebas, Celia, Barnes, James B., Reading, Patrick C., Young, Paul R., Watterson, Daniel, Dubois, Patrice M., Collin, Nicolas and Chappell, Keith J. (2022). Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine. Frontiers in Immunology, 13 976968, 976968. doi: 10.3389/fimmu.2022.976968

Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine

2022

Journal Article

A platform technology for generating subunit vaccines against diverse viral pathogens

Young, Andrew, Isaacs, Ariel, Scott, Connor A. P., Modhiran, Naphak, McMillan, Christopher L. D., Cheung, Stacey T. M., Barr, Jennifer, Marsh, Glenn, Thakur, Nazia, Bailey, Dalan, Li, Kenneth S. M., Luk, Hayes K. H., Kok, Kin-Hang, Lau, Susanna K. P., Woo, Patrick C. Y., Furuyama, Wakako, Marzi, Andrea, Young, Paul R., Chappell, Keith J. and Watterson, Daniel (2022). A platform technology for generating subunit vaccines against diverse viral pathogens. Frontiers in Immunology, 13 963023, 1-16. doi: 10.3389/fimmu.2022.963023

A platform technology for generating subunit vaccines against diverse viral pathogens

2022

Journal Article

Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern

McMillan, Christopher L.D., Amarilla, Alberto A., Modhiran, Naphak, Choo, Jovin J.Y., Azuar, Armira, Honeyman, Kate E., Khromykh, Alexander A., Young, Paul R., Watterson, Daniel and Muller, David A. (2022). Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern. Vaccine, 40 (34), 4929-4932. doi: 10.1016/j.vaccine.2022.07.013

Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern

2022

Journal Article

Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions

Blyton, Michaela D. J., Young, Paul R., Moore, Ben D. and Chappell, Keith J. (2022). Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions. Proceedings of the National Academy of Sciences, 119 (33) e2122680119, 1-11. doi: 10.1073/pnas.2122680119

Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions

2022

Journal Article

Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants

Isaacs, Ariel, Amarilla, Alberto A., Aguado, Julio, Modhiran, Naphak, Albornoz, Eduardo A., Baradar, Alireza A., McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, McMillan, Nigel A. J., Muller, David A., Young, Paul R., Woodruff, Trent M., Wolvetang, Ernst J., Chappell, Keith J. and Watterson, Daniel (2022). Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants. Frontiers in Immunology, 13 926262, 926262. doi: 10.3389/fimmu.2022.926262

Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants

Current funding

  • 2023 - 2025
    Development of monovalent type 1 and trivalent poliovirus VLP patches
    Global Polio Eradication Initiative
    Open grant
  • 2023 - 2028
    Building the next mRNA vaccines and therapies
    MRFF - National Critical Infrastructure Initiative
    Open grant
  • 2023 - 2025
    Phase 2 clinical study for a next-generation, needle free COVID-19 vaccine CRC-P administered by Vaxxas Pty Ltd)
    Vaxxas Pty Ltd
    Open grant
  • 2023 - 2025
    CRACing the role of the Flavivirus NS1 protein
    NHMRC IDEAS Grants
    Open grant
  • 2020 - 2024
    Rapid Acceleration of the UQ COVID-19 vaccine in Conjunction Program
    Queensland Department of State Development, Tourism and Innovation
    Open grant

Past funding

  • 2022 - 2023
    An integrated analytical network for protein characterisation
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2021 - 2022
    Molecular Clamp Stabilised HTLV-1 Envelope Glycoprotein for Vaccination and Immunotherapy
    Australian Centre for HIV and Hepatitis Virology Research (ACH2)
    Open grant
  • 2020 - 2022
    Preclinical evaluation of Nanopatch-delivered poliovirus virus-like particles, and to explore co-formulation with dmLT
    Global Polio Eradication Initiative
    Open grant
  • 2020 - 2022
    Molecular Clamp Stabilized Spike Vaccine for Rapid Response
    NHMRC MRFF EPCDR - Novel Coronavirus Vaccine Development
    Open grant
  • 2020 - 2023
    Rapid Acceleration of the UQ COVID-19 Vaccine Program
    NHMRC MRFF Coronavirus Research Response
    Open grant
  • 2020 - 2023
    Chimeric insect-specific viruses as novel vaccines for mosquito-borne diseases
    NHMRC Development Grant
    Open grant
  • 2019
    A versatile accurate mass, high resolution QTOF mass spectrometer for chemistry and proteomic applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2021
    Clamp stabilized vaccines to provide broad spectrum protection against influenza
    NHMRC Development Grant
    Open grant
  • 2019
    Cyto-Mine to accelerate Cell Line Development for Vaccines and Biopharmaceuticals
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2021
    High resolution structural determination of pathogenic flaviviruses by cryo-EM using a chimeric platform
    NHMRC Project Grant
    Open grant
  • 2019 - 2020
    Replacement of Wet - lab machinery in the UQ Glassblowing Facility
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2019 - 2022
    Structural insights into the function and antigenicity of the flavivirus NS1 protein
    NHMRC Project Grant
    Open grant
  • 2018
    Cryoelectron Microscopy Platform for Cellular Structural Biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Epifluorescent and live-cell imaging microscopes for the investigation of host-pathogen interactions and for molecular and cellular biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2022
    Koala retrovirus epidemic: genetic diversity, genome invasion and disease
    ARC Discovery Projects
    Open grant
  • 2018 - 2021
    Needle free delivery of dengue and Zika vaccines to the skin
    NHMRC Development Grant
    Open grant
  • 2018 - 2019
    Replacement of glassworking lathe and wet-lab machinery in the UQ Glassblowing Facility
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2018 - 2021
    Virus vaccines that ensure preparedness against future public health emergencies
    NHMRC Project Grant
    Open grant
  • 2017 - 2022
    How a ubiquitous endosymbiont of insects protects against pathogens
    ARC Discovery Projects
    Open grant
  • 2017 - 2022
    The genetic basis of pathogen blocking: elucidating the contributions of the Wolbachia, dengue virus and mosquito genomes
    NHMRC Project Grant
    Open grant
  • 2017 - 2018
    Inactivation of Yellow Fever virus in plasma and in platelet concentrates following treatment with the THERAFLEX pathogen inactivation technologies
    UniQuest Pty Ltd
    Open grant
  • 2017 - 2018
    The role of asthma in the generation of influenza virus quasispecies
    UQ Development Fellowships
    Open grant
  • 2017 - 2019
    Preclinical development of a Nanopatch measles-rubella vaccine microarray patch (Bill & Melinda Gates Foundation grant administered by Vaxxas)
    Vaxxas Pty Ltd
    Open grant
  • 2017 - 2023
    ARC Training Centre for Biopharmaceutical Innovation
    ARC Industrial Transformation Training Centres
    Open grant
  • 2016 - 2017
    Atomo Dengue Fever Diagnostics (NS1 antibodies)
    UniQuest Pty Ltd
    Open grant
  • 2016 - 2017
    Implicit Biosciences: Toll-Like Receptor 4 antagonists as a Dengue Virus Therapeutic
    UniQuest Pty Ltd
    Open grant
  • 2016 - 2017
    Development of inactivated polio virus vaccine Nanopatch product
    Innovation Connections
    Open grant
  • 2016 - 2017
    Inactivation of Zika virus in plasma and in platelet concentrates following treatment with the THERAFLEX pathogen inactivation technologies
    UniQuest Pty Ltd
    Open grant
  • 2016 - 2019
    Dengue virus NS1 protein as a mediator of pathology
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    How a ubiquitous endosymbiont of insects protects against pathogens (ARC Discovery Project administered by Monash University)
    Monash University
    Open grant
  • 2016 - 2017
    The genetic basis of pathogen blocking: elucidating the contributions of the Wolbachia, dengue virus and mosquito genomes (NHMRC Project Grant administered by Monash University)
    Monash University
    Open grant
  • 2016 - 2017
    Upgrade to glasswork lathe
    UQ Major Research Facility Fund
    Open grant
  • 2015 - 2017
    Next-gen diagnostics for field-based surveillance of Wolbachia and arboviral infections in wild mosquitoes
    Bill & Melinda Gates Foundation
    Open grant
  • 2015 - 2016
    Reaching new heights in high-resolution electron microscopy
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2015 - 2016
    Effect of THERAFLEX MB plasma on the infectivity of Chikungunya and Dengue viruses
    UniQuest Pty Ltd
    Open grant
  • 2015 - 2017
    Host metabolism and responses contributing to flavivirus replication and pathogenesis (NHMRC Project administered by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2014 - 2015
    Dengue virus assay validation
    UniQuest Pty Ltd
    Open grant
  • 2014
    A confocal microscope for investigation of live bacterial and viral pathogens and for molecular cell biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014 - 2017
    Dengue virus vaccine production in the microalgae Chlamydomonas reinhardtii
    NHMRC Development Grant
    Open grant
  • 2014 - 2017
    Micropatch kits for extraction and detection of circulating biomarkers from skin
    NHMRC Development Grant
    Open grant
  • 2014 - 2017
    The dengue virus glycoprotein NS1 binds cholesterol and mediates cellular activation
    NHMRC Project Grant
    Open grant
  • 2013 - 2014
    Antiviral testing of synthetic compounds designed to inhibit the activity of the fusion protein of respiratory syncytial virus.
    UniQuest Pty Ltd
    Open grant
  • 2013 - 2018
    Determine the antiviral potential of synthetic compounds designed to inhibit the activity of the fusion protein of respiratory syncytial virus
    UniQuest Pty Ltd
    Open grant
  • 2013 - 2014
    Dengue virus inactivation III with Theraflex
    UniQuest Pty Ltd
    Open grant
  • 2013 - 2014
    Dengue virus inactivation with Mirasol II
    UniQuest Pty Ltd
    Open grant
  • 2013 - 2015
    Stealth liposomes and siRNA for the treatment of respiratory viral infections (NHMRC project grant led by Griffith University)
    Griffith University
    Open grant
  • 2012 - 2015
    The first integrated multimodal assay for the ultrasensitive detection of dengue contamination of blood
    ARC Linkage Projects
    Open grant
  • 2012
    Coaxing Dengue into Holding its Breath
    UQ - Purdue University Early Career Mobility Scheme
    Open grant
  • 2012 - 2015
    Activation of the Respiratory Syncytial virus fusion protein
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Flaviviral proteases as viable targets for antiinfective drugs
    NHMRC Project Grant
    Open grant
  • 2011 - 2012
    Antiviral activity of compounds against respiratory syncytial virus
    UniQuest Pty Ltd
    Open grant
  • 2011
    Cell culture facilities for studying host-pathogen interactions and immune function
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    Real time cell analysis for biological and drug discovery applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2013
    Retroviral invasion of the koala genome: prevalence, transmission and role in immunosuppressive disease
    ARC Linkage Projects
    Open grant
  • 2010 - 2012
    A functional interaction between domains of the flavivirus NS5 protein presents a new target for antiviral therapy
    NHMRC Project Grant
    Open grant
  • 2010
    An integrated high -throughput fluorescence imaging facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Resonant waveguide label-free plate sensor
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2013
    The role of subgenomic non-coding viral RNA in flavivirus pathogenicity
    NHMRC Project Grant
    Open grant
  • 2009 - 2012
    Koala disease research program - koala retrovirus (KoRV)
    Australia Zoo Wildlife Warriors Worldwide Ltd
    Open grant
  • 2009 - 2012
    Detection of imported exotic strains of West Nile virus for national biosecurity surveillance.
    ARC Discovery Projects
    Open grant
  • 2009
    Infrastructure for biochemistry and infectious disease resarch in molecualr biosciences
    UQ School/Centre Co-Funding
    Open grant
  • 2008 - 2010
    RNAi therapeutic intervention of human viral respiratory disease
    University of Canberra
    Open grant
  • 2008 - 2010
    Investigating A novel generic Approach to Anti-Infective Agents
    NHMRC Project Grant
    Open grant
  • 2008 - 2010
    Molecular characterization of dengue virus fusion and antiviral inhibitors
    NHMRC Project Grant
    Open grant
  • 2008
    Molecular Epidemiology and pathogenesis of mosquito-borne viruses
    NHMRC Equipment Grant
    Open grant
  • 2008 - 2010
    Retroviral invasion of the koala genome: Where did it come from and what is it doing now that its there?
    ARC Discovery Projects
    Open grant
  • 2007 - 2009
    Inhibitors Of West Nile Virus Protease As Antiviral Drugs
    NHMRC Project Grant
    Open grant
  • 2007
    Molecular characterization of dengue virus fusion and development of antiviral inhibitors
    UQ External Support Enabling Grant
    Open grant
  • 2007 - 2010
    Viral factors involved in flavivirus replication and virus-host interactions
    NHMRC Project Grant
    Open grant
  • 2006 - 2009
    Development and commercialization of novel diagnostic assays for the early detection of acute dengue virus infection
    ARC Linkage Projects
    Open grant
  • 2006
    Real time PCR and nanoparticle diagnostic facilities for high-throughput quantitative analysis of genomic structure and gene expression
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2005 - 2006
    ESEG_Structure-function studies of the respiratory syncytial virus fusion F protein
    NHMRC Project Grant
    Open grant
  • 2005 - 2006
    Development of dengue antigen detection assay based on NS1, for the early diagnosis of dengue infection
    PAN BIO PTY LTD
    Open grant
  • 2005
    Research into retrovirus in koalas
    Wildcare Australia
    Open grant
  • 2005
    The West Nile viral protease NS3: a target for antiviral drug and vaccine design
    NHMRC Project Grant
    Open grant
  • 2004 - 2006
    High resolution single particle analysis of biological macromolecules
    ARC Discovery Projects
    Open grant
  • 2004 - 2007
    Understanding the role of a newly recognised retrovirus in the induction of cancer and immunosuppressive disease in koalas
    ARC Linkage Projects
    Open grant
  • 2003 - 2005
    Molecular basis of Dengue Virus-induced fusion
    NHMRC Project Grant
    Open grant
  • 2003
    Monolayer crystallization of membrane proteins
    ARC Discovery Projects
    Open grant
  • 2000 - 2002
    RSV Fusion Project
    BIOTA Respiratory Research Pty Ltd
    Open grant
  • 2000
    Recombinant baculovirus and nucleic acid based dengue virus vaccines
    World Health Organisation
    Open grant
  • 2000
    DNA- and VLP- based vaccines for respiratory synctial virus infections
    Ramaciotti Foundation
    Open grant
  • 1996 - 1997
    A mass spectrometric facility for peptide and protein analysis at the University of Queensland
    Viertel Foundation (Sylvia and Charles Viertel)
    Open grant

Availability

Professor Paul Young is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

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