
Overview
Background
I am a passionate neuroscientist, working as a Postdoctoral Researcher at the School of Biomedical Sciences (SBMS, UQ).
I have always had a deep interest in Medicine and Biology, which brought me to first successfully complete a bachelor degree in Medicine and Surgery in 2013 (University of Insubria, Italy), and then a PhD in Neuroscience in 2019 (Queensland Brain Institute, QBI, UQ). My PhD investigated how the connections of the cerebral cortex develop and evolve in different animal species, with a specific focus on the plasticity of these connections in health and disease.
During my first Postdoctoral experience in the laboratories of Dr Opazo and A/Prof Anggono (QBI, UQ), I worked on a project involving cutting-edge live-cell imaging using a two-photon microscope to investigate how key molecules are distributed in the brain during neuronal plasticity, both in vitro and in vivo, followed by behavioural assays.
Thanks to this experience, I gained unique surgical, behavioural, and imaging expertise that I am now employing to answer questions of brain evolution and development in the laboratories of Dr Fenlon and A/Prof Suárez at SBMS. In my current position I am investigating how the different timing (heterochrony) of developmental processes in brain development can cause dramatic changes in the final brain structure, both in the context of evolution as well as disease.
Availability
- Dr Annalisa Paolino is:
- Available for supervision
Qualifications
- Bachelor (Honours) of Medicine Surgery, Università degli Studi dell'Insubria Varese e Como
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Annalisa Paolino’s works on UQ eSpace
2024
Journal Article
Learning-induced remodelling of inhibitory synapses in the motor cortex
Bhembre, Nishita, Paolino, Annalisa, Das, Sooraj S., Guntupalli, Sumasri, Fenlon, Laura R. and Anggono, Victor (2024). Learning-induced remodelling of inhibitory synapses in the motor cortex. Open Biology, 14 (11) 240109, 1-9. doi: 10.1098/rsob.240109
2023
Journal Article
Non-uniform temporal scaling of developmental processes in the mammalian cortex
Paolino, Annalisa, Haines, Elizabeth H., Bailey, Evan J., Black, Dylan A., Moey, Ching, García-Moreno, Fernando, Richards, Linda J., Suárez, Rodrigo and Fenlon, Laura R. (2023). Non-uniform temporal scaling of developmental processes in the mammalian cortex. Nature Communications, 14 (1) 5950, 1-17. doi: 10.1038/s41467-023-41652-5
2023
Journal Article
Cortical activity emerges in region-specific patterns during early brain development
Suárez, Rodrigo, Bluett, Tobias, McCullough, Michael H., Avitan, Lilach, Black, Dylan A., Paolino, Annalisa, Fenlon, Laura R., Goodhill, Geoffrey J. and Richards, Linda J. (2023). Cortical activity emerges in region-specific patterns during early brain development. Proceedings of the National Academy of Sciences, 120 (22) e2208654120, e2208654120. doi: 10.1073/pnas.2208654120
2023
Other Outputs
Raw data for "Cortical activity emerges in region-specific patterns during early brain development. Suárez et al., PNAS 2023"
Suarez, Rodrigo, Bluett, Tobias, McCullough, Michael, Avitan, Lilach, Paolino, Annalisa, Fenlon, Laura, Goodhill, Geoffrey and Richards, Linda (2023). Raw data for "Cortical activity emerges in region-specific patterns during early brain development. Suárez et al., PNAS 2023". The University of Queensland. (Dataset) doi: 10.48610/5ccfb47
2022
Journal Article
Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes
Kozulin, Peter, Suárez, Rodrigo, Zhao, Qiong-Yi, Paolino, Annalisa, Richards, Linda J. and Fenlon, Laura R. (2022). Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes. Development, 149 (3) dev200212. doi: 10.1242/dev.200212
2020
Journal Article
Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution
Paolino, Annalisa, Fenlon, Laura R., Kozulin, Peter, Haines, Elizabeth, Lim, Jonathan W. C., Richards, Linda J. and Suárez, Rodrigo (2020). Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution. Proceedings of the National Academy of Sciences, 117 (19), 201922422-10564. doi: 10.1073/pnas.1922422117
2019
Other Outputs
Conserved and divergent mechanisms of cortical development across mammalian brain evolution
Paolino, Annalisa (2019). Conserved and divergent mechanisms of cortical development across mammalian brain evolution. PhD Thesis, Queensland Brain Institute, The University of Queensland. doi: 10.14264/uql.2019.401
2018
Journal Article
Transcriptional control of long-range cortical projections
Paolino, Annalisa, Fenlon, Laura R., Suárez, Rodrigo and Richards, Linda J. (2018). Transcriptional control of long-range cortical projections. Current Opinion in Neurobiology, 53, 57-65. doi: 10.1016/j.conb.2018.05.005
2018
Journal Article
A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum
Suárez, Rodrigo, Paolino, Annalisa, Fenlon, Laura R., Morcom, Laura R., Kozulin, Peter, Kurniawan, Nyoman D. and Richards, Linda J. (2018). A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum. Proceedings of the National Academy of Sciences, 115 (38), 9622-9627. doi: 10.1073/pnas.1808262115
2018
Journal Article
Multiple events of gene manipulation via in pouch electroporation in a marsupial model of mammalian forebrain development
Paolino, Annalisa, Fenlon, Laura R., Kozulin, Peter, Richards, Linda J. and Suarez, Rodrigo (2018). Multiple events of gene manipulation via in pouch electroporation in a marsupial model of mammalian forebrain development. Journal of Neuroscience Methods, 293, 45-52. doi: 10.1016/j.jneumeth.2017.09.004
2017
Journal Article
Development of body, head and brain features in the Australian fat-tailed dunnart (Sminthopsis crassicaudata; Marsupialia: Dasyuridae); A postnatal model of forebrain formation
Suarez, Rodrigo, Paolino, Annalisa, Kozulin, Peter, Fenlon, Laura R., Morcom, Laura R., Englebright, Robert, O'Hara, Patricia J., Murray, Peter J. and Richards, Linda J. (2017). Development of body, head and brain features in the Australian fat-tailed dunnart (Sminthopsis crassicaudata; Marsupialia: Dasyuridae); A postnatal model of forebrain formation. Plos One, 12 (9) e0184450, 1-18. doi: 10.1371/journal.pone.0184450
2017
Journal Article
Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals
Gobius, Ilan, Suarez, Rodrigo, Morcom, Laura, Paolino, Annalisa, Edwards, Timothy J., Kozulin, Peter and Richards, Linda J. (2017). Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals. Neural Development, 12 (1) 9, 9. doi: 10.1186/s13064-017-0086-1
2017
Journal Article
Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance
Marsh, Ashley P. L., Heron, Delphine, Edwards, Timothy J., Quartier, Angelique, Galea, Charles, Nava, Caroline, Rastetter, Agnes, Moutard, Marie-Laure, Anderson, Vicki, Bitoun, Pierre, Bunt, Jens, Faudet, Anne, Garel, Catherine, Gillies, Greta, Gobius, Ilan, Guegan, Justine, Heide, Solveig, Keren, Boris, Lesne, Fabien, Lukic, Vesna, Mandelstam, Simone A., McGillivray, George, McIlroy, Alissandra, Meneret, Aurelie, Mignot, Cyril, Morcom, Laura R., Odent, Sylvie, Paolino, Annalisa, Pope, Kate ... Depienne, Christel (2017). Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance. Nature Genetics, 49 (4), 511-514. doi: 10.1038/ng.3794
2017
Journal Article
NT-proBNP as marker of ventricular dilatation and pulmonary regurgitation after surgical correction of Tetralogy of Fallot: a MRI validation study
Paolino, Annalisa, Hussain, Tarique, Pavon, Antonio, Velasco, Maria Nieves, Uribe, Sergio, Ordonez, Antonio and Valverde, Israel (2017). NT-proBNP as marker of ventricular dilatation and pulmonary regurgitation after surgical correction of Tetralogy of Fallot: a MRI validation study. Pediatric Cardiology, 38 (2), 324-331. doi: 10.1007/s00246-016-1516-2
2015
Conference Publication
Developmental scenarios for the evolutionary origin of the corpus callosum
Suarez, R., Paolino, A., Kozulin, P., Morcom, L., Fenlon, L. and Richards, L. (2015). Developmental scenarios for the evolutionary origin of the corpus callosum. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188
Supervision
Availability
- Dr Annalisa Paolino is:
- Available for supervision
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