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Dr Annalisa Paolino
Dr

Annalisa Paolino

Email: 

Overview

Background

I am a passionate neuroscientist, working as a Postdoctoral Researcher at the School of Biomedical Sciences (SBMS, UQ).

I have always had a deep interest in Medicine and Biology, which brought me to first successfully complete a bachelor degree in Medicine and Surgery in 2013 (University of Insubria, Italy), and then a PhD in Neuroscience in 2019 (Queensland Brain Institute, QBI, UQ). My PhD investigated how the connections of the cerebral cortex develop and evolve in different animal species, with a specific focus on the plasticity of these connections in health and disease.

During my first Postdoctoral experience in the laboratories of Dr Opazo and A/Prof Anggono (QBI, UQ), I worked on a project involving cutting-edge live-cell imaging using a two-photon microscope to investigate how key molecules are distributed in the brain during neuronal plasticity, both in vitro and in vivo, followed by behavioural assays.

Thanks to this experience, I gained unique surgical, behavioural, and imaging expertise that I am now employing to answer questions of brain evolution and development in the laboratories of Dr Fenlon and A/Prof Suárez at SBMS. In my current position I am investigating how the different timing (heterochrony) of developmental processes in brain development can cause dramatic changes in the final brain structure, both in the context of evolution as well as disease.

Availability

Dr Annalisa Paolino is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Medicine Surgery, Università degli Studi dell'Insubria Varese e Como
  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Annalisa Paolino’s works on UQ eSpace

15 works between 2015 and 2023

1 - 15 of 15 works

2023

Journal Article

Non-uniform temporal scaling of developmental processes in the mammalian cortex

Paolino, Annalisa, Haines, Elizabeth H., Bailey, Evan J., Black, Dylan A., Moey, Ching, García-Moreno, Fernando, Richards, Linda J., Suárez, Rodrigo and Fenlon, Laura R. (2023). Non-uniform temporal scaling of developmental processes in the mammalian cortex. Nature Communications, 14 (1) 5950, 1-17. doi: 10.1038/s41467-023-41652-5

Non-uniform temporal scaling of developmental processes in the mammalian cortex

2023

Journal Article

Cortical activity emerges in region-specific patterns during early brain development

Suárez, Rodrigo, Bluett, Tobias, McCullough, Michael, Avitan, Lilach, Paolino, Annalisa, Fenlon, Laura R., Goodhill, Geoffrey J. and Richards, Linda J. (2023). Cortical activity emerges in region-specific patterns during early brain development. Proceedings of the National Academy of Sciences.

Cortical activity emerges in region-specific patterns during early brain development

2023

Journal Article

Cortical activity emerges in region-specific patterns during early brain development

Suárez, Rodrigo, Bluett, Tobias, McCullough, Michael H., Avitan, Lilach, Black, Dylan A., Paolino, Annalisa, Fenlon, Laura R., Goodhill, Geoffrey J. and Richards, Linda J. (2023). Cortical activity emerges in region-specific patterns during early brain development. Proceedings of the National Academy of Sciences, 120 (22) e2208654120, e2208654120. doi: 10.1073/pnas.2208654120

Cortical activity emerges in region-specific patterns during early brain development

2023

Other Outputs

Raw data for "Cortical activity emerges in region-specific patterns during early brain development. Suárez et al., PNAS 2023"

Suarez, Rodrigo, Bluett, Tobias, McCullough, Michael, Avitan, Lilach, Paolino, Annalisa, Fenlon, Laura, Goodhill, Geoffrey and Richards, Linda (2023). Raw data for "Cortical activity emerges in region-specific patterns during early brain development. Suárez et al., PNAS 2023". The University of Queensland. (Dataset) doi: 10.48610/5ccfb47

Raw data for "Cortical activity emerges in region-specific patterns during early brain development. Suárez et al., PNAS 2023"

2022

Journal Article

Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes

Kozulin, Peter, Suárez, Rodrigo, Zhao, Qiong-Yi, Paolino, Annalisa, Richards, Linda J. and Fenlon, Laura R. (2022). Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes. Development, 149 (3) dev200212. doi: 10.1242/dev.200212

Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes

Featured

2020

Journal Article

Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution

Paolino, Annalisa, Fenlon, Laura R., Kozulin, Peter, Haines, Elizabeth, Lim, Jonathan W. C., Richards, Linda J. and Suárez, Rodrigo (2020). Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution. Proceedings of the National Academy of Sciences, 117 (19), 201922422-10564. doi: 10.1073/pnas.1922422117

Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution

2019

Other Outputs

Conserved and divergent mechanisms of cortical development across mammalian brain evolution

Paolino, Annalisa (2019). Conserved and divergent mechanisms of cortical development across mammalian brain evolution. PhD Thesis, Queensland Brain Institute, The University of Queensland. doi: 10.14264/uql.2019.401

Conserved and divergent mechanisms of cortical development across mammalian brain evolution

2018

Journal Article

Transcriptional control of long-range cortical projections

Paolino, Annalisa, Fenlon, Laura R., Suárez, Rodrigo and Richards, Linda J. (2018). Transcriptional control of long-range cortical projections. Current Opinion in Neurobiology, 53, 57-65. doi: 10.1016/j.conb.2018.05.005

Transcriptional control of long-range cortical projections

2018

Journal Article

A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum

Suárez, Rodrigo, Paolino, Annalisa, Fenlon, Laura R., Morcom, Laura R., Kozulin, Peter, Kurniawan, Nyoman D. and Richards, Linda J. (2018). A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum. Proceedings of the National Academy of Sciences, 115 (38), 9622-9627. doi: 10.1073/pnas.1808262115

A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum

2018

Journal Article

Multiple events of gene manipulation via in pouch electroporation in a marsupial model of mammalian forebrain development

Paolino, Annalisa, Fenlon, Laura R., Kozulin, Peter, Richards, Linda J. and Suarez, Rodrigo (2018). Multiple events of gene manipulation via in pouch electroporation in a marsupial model of mammalian forebrain development. Journal of Neuroscience Methods, 293, 45-52. doi: 10.1016/j.jneumeth.2017.09.004

Multiple events of gene manipulation via in pouch electroporation in a marsupial model of mammalian forebrain development

2017

Journal Article

Development of body, head and brain features in the Australian fat-tailed dunnart (Sminthopsis crassicaudata; Marsupialia: Dasyuridae); A postnatal model of forebrain formation

Suarez, Rodrigo, Paolino, Annalisa, Kozulin, Peter, Fenlon, Laura R., Morcom, Laura R., Englebright, Robert, O'Hara, Patricia J., Murray, Peter J. and Richards, Linda J. (2017). Development of body, head and brain features in the Australian fat-tailed dunnart (Sminthopsis crassicaudata; Marsupialia: Dasyuridae); A postnatal model of forebrain formation. Plos One, 12 (9) e0184450, 1-18. doi: 10.1371/journal.pone.0184450

Development of body, head and brain features in the Australian fat-tailed dunnart (Sminthopsis crassicaudata; Marsupialia: Dasyuridae); A postnatal model of forebrain formation

2017

Journal Article

Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals

Gobius, Ilan, Suarez, Rodrigo, Morcom, Laura, Paolino, Annalisa, Edwards, Timothy J., Kozulin, Peter and Richards, Linda J. (2017). Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals. Neural Development, 12 (1) 9, 9. doi: 10.1186/s13064-017-0086-1

Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals

2017

Journal Article

Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance

Marsh, Ashley P. L., Heron, Delphine, Edwards, Timothy J., Quartier, Angelique, Galea, Charles, Nava, Caroline, Rastetter, Agnes, Moutard, Marie-Laure, Anderson, Vicki, Bitoun, Pierre, Bunt, Jens, Faudet, Anne, Garel, Catherine, Gillies, Greta, Gobius, Ilan, Guegan, Justine, Heide, Solveig, Keren, Boris, Lesne, Fabien, Lukic, Vesna, Mandelstam, Simone A., McGillivray, George, McIlroy, Alissandra, Meneret, Aurelie, Mignot, Cyril, Morcom, Laura R., Odent, Sylvie, Paolino, Annalisa, Pope, Kate ... Depienne, Christel (2017). Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance. Nature Genetics, 49 (4), 511-514. doi: 10.1038/ng.3794

Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance

2017

Journal Article

NT-proBNP as marker of ventricular dilatation and pulmonary regurgitation after surgical correction of Tetralogy of Fallot: a MRI validation study

Paolino, Annalisa, Hussain, Tarique, Pavon, Antonio, Velasco, Maria Nieves, Uribe, Sergio, Ordonez, Antonio and Valverde, Israel (2017). NT-proBNP as marker of ventricular dilatation and pulmonary regurgitation after surgical correction of Tetralogy of Fallot: a MRI validation study. Pediatric Cardiology, 38 (2), 324-331. doi: 10.1007/s00246-016-1516-2

NT-proBNP as marker of ventricular dilatation and pulmonary regurgitation after surgical correction of Tetralogy of Fallot: a MRI validation study

2015

Conference Publication

Developmental scenarios for the evolutionary origin of the corpus callosum

Suarez, R., Paolino, A., Kozulin, P., Morcom, L., Fenlon, L. and Richards, L. (2015). Developmental scenarios for the evolutionary origin of the corpus callosum. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188

Developmental scenarios for the evolutionary origin of the corpus callosum

Funding

Current funding

  • 2024 - 2027
    How do developmental imbalances of neural activity lead to autism spectrum disorder?
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2021 - 2022
    Dr Annalisa Paolino - AQ WRAP
    Advance Queensland Women's Research Assistance Program
    Open grant

Supervision

Availability

Dr Annalisa Paolino is:
Available for supervision

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Media

Enquiries

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